JamesCCusackMD

PubMed

• ASO Visual Abstract: Trends and Determinants of Location of Death Due to Colorectal Cancer in the USA: A Nationwide Study.
  Swati Sonal, Bhav Jain, Simar S Bajaj, Edward Christopher Dee, Chloe Boudreau
  Annals of Surgical Oncology. 2024-03-01
• 2 citations
  Trends and Determinants of Location of Death Due to Colorectal Cancer in the United States : A Nationwide Study.
  Swati Sonal, Bhav Jain, Simar S Bajaj, Edward Christopher Dee, Chloe Boudreau
  Annals of Surgical Oncology. 2024-03-01
• 9 citations
  The Impact of the Gut Microbiome, Environment, and Diet in Early-Onset Colorectal Cancer Development.
  Rui Dai, Bridget N Kelly, Amarachi Ike, David Berger, Andrew Chan
  Cancers. 2024-02-05

Journal Articles

• Prognostic and Predictive Biomarkers in Colorectal Cancer: Implications for the Clinical Surgeon  
  Erstad DJ, Tumusiime G, Cusack JC, Ann Surg Oncol, 1/1/2015
• A critical look at local-regional management of peritoneal metastasis  
  Chan CHF, Cusack, JC, Ryan DP, Hem Onc Clinics N Am, 1/1/2015
• Mutational Analysis of Merkel Cell Carcinoma  
  Erstad D, Cusack JC, Cancers, 1/1/2014
• Current Status of Imaging and Emerging Techniques to Evaluate Liver Metastases from Colorectal Cancer  
  Sahani DV, Bajwa MA, Andrabi Y, Bajpai S, Cusack JC, Ann Surg, 1/1/2014
• Phase I/II Study of Neoadjuvant Bevacizumab, Erlotinib and 5-fluorouracil with Concurrent External Beam Radiation Therapy in Locally Advanced Rectal Cancer  
  Blaszkowsky LS, Ryan DP, Szymonifka J, Borger DR, Zhu AX, Kwak EL, Mamon HJ, Allen JN, Vasudev E, Shellito PC, Cusack JC, Berger DL, Hong TS, Ann Oncol, 1/1/2014
• Mutational and clinical predictors of pathologic complete response in the treatment of locally advanced rectal cancer  
  Russo AL, Ryan DP, Borger DR, Wo JY, Szymonifka J, Liang W-Y, Kwak EL, Blaszkowsky LS, Clark JW, Allen JN, Zhu AX, Berger DL, Cusack JC, Haigis KM, Hong TS, Journal of Gastrointest Cancer, 1/1/2014
• Merkel Cell Carcinoma: 30-Year Experience from a Single Institution  
  Santamaria-Barria JA, Boland GM, Yeap BY, Nardi V, Dias-Santagata D, Cusack JC, Ann Surg Onc, 1/1/2013
• Targeting NF-kappaB Signaling in Cancer Therapy  
  Erstad D, Cusack JC, Surg Oncol Clin N Am, 1/1/2013
• XPO1 and BRAF inhibition synergize and induce melanoma regression  
  Salas Fragomeni RA, Chung HW, Landesman Y, Senapedis W, Saint-Martin J-R, Tsao H, Flaherty K, Shacham S, Kauffman M, Cusack JC, Molecular Cancer Therapeutics, 1/1/2013
• Inhibition of Herpes simplex virus 1 oncolysis by chemotherapy  
  Kawasaki H, Kulu Y, Donahue JM, Kasuya H, Cusack JC, Choi EW, Kuruppu DK, Fuchs BC, and Tanabe KT, Cancer Gene Ther, 1/1/2013
• Hereditary Breast and Ovarian Cancer and Other Hereditary Syndromes: Using Technology to Identify Carriers  
  Drohan B, Roche CA, Cusack JC, Hughes KS, Ann Surg Oncol, 1/1/2012
• Antiproteasomal agents in rectal cancer  
  Conrad C, Podolsky MJ, Cusack JC, Anti-Cancer Drugs, 1/1/2011
• Marizomib, a proteasome inhibitor for all seasons: preclinical profile and a framework for clinical trials  
  Potts B, Albitar MX, Anderson KC, Baritaki S, Berkers C, Bonavida B, Chandra J, Chauhan D, Cusack JC, Fenical W, Ghobrial IM, Groll M, Jensen PR, Lam KS, Lloyd GK, McB..., Current Cancer Drug Targets, 1/1/2011
• A 58-Year-Old Woman with a Mass in the Liver  
  Cusack JC, Clark JW, Curley SA, Sahani DV, Zuckerberg LR, N Engl J Med, 1/1/2011
• Effects of neo-adjuvant chemoradiation therapy on the diagnostic value of lymph nodes after rectal cancer surgery  
  Klos CL, Shellito PC, Rattner DW, Hodin RA, Cusack JC, Bordeianou L, Sylla P, Hong TS, Blaszkowsky L, Ryan DP, Lauwers GY, Chang Y Berger DL, American Journal of Surgery, 1/1/2010
• Extra-adrenal pheochromocytoma occurring at the organ of Zuckerkandl  
  Donahue J, Sahani D, Tso L, Cusack JC, Surgery, 1/1/2008
• Membrane-bound heparin-binding epidermal growth factor-like growth factor (HB-EGF) regulates E-cadherin expression in pancreatic carcinoma cells  
  Wang F, Sloss C, Zhang X, Lee SW, Cusack JC, Cancer Res, 1/1/2007
• NPI-0052 enhances the tumoricidal response to conventional cancer therapy in a colon cancer model  
  Cusack JC, Liu R, Xia L, Chao TH, Pien C, Niu W, Palombella VJ, Neuteboom ST, Palladino MA, Clin Cancer Res, 1/1/2006
• A Phase 1 study of bortezomib plus irinotecan in patients with advanced solid tumors  
  Ryan DP, O'Neil BH, Supko JG, Rocha Lima CM, Dees EC, Appleman LJ, Clark J, Fidias P, Orlowski RZ, Kashala O, Eder JP, Cusack JC, Cancer, 1/1/2006
• Successful minimally invasive parathyroidectomy without using intra-operative parathyroid hormone assays  
  Ollila DW, Caudle AS, Cance WG, Kim HJ, Cusack JC, Swasey JE, Calvo BF, Am J Surg, 1/1/2006
• Overcoming anti-apoptotic responses to promote chemosensitivity in metastatic colorectal cancer to the liver  
  Cusack J, Ann Surg Oncol, 1/1/2003
• Doxorubicin-induced NF-kappaB activation in breast cancer is overcome by proteasome inhibition, resulting in enhanced tumoricidal response to treatment  
  Thornton JD, Liu R, Orlowski RZ, Elliot P, Adams J, Baldwin AS, Cusack JC, Surg Forum, 1/1/2001
• Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: Implications for systemic NF-kappaB Inhibition  
  Cusack JC, Liu R, Houston MA, Abendroth K, Elliott PJ, Adams J, Baldwin AS, Cancer Res, 1/1/2001
• Inducible chemoresistance to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin (CPT-11) in colorectal cancer cells and a xenograft model is overcome b...  
  Cusack JC, Liu R, Baldwin AS, Cancer Res, 1/1/2000
• Fas and Fas ligand interactions in malignant disease (review)  
  Owen-Schaub L, Chan H, Cusack JC, Roth J, Hill LL, Int J Oncl, 1/1/2000
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Books/Book Chapters

• Current Surgical Therapy 
  Chapter: The Management of Pheochromocytoma 
  Page 636.0 - 642.0Cusack JC, Phitayakorn REditors: Cameron JL and Cameron AM.Elsevier, New YorkEdition 11th,2014
• UpToDate online 
  Chapter: Diagnosis and staging of small bowel neoplasms 
  Cusack JC, Overman MJ, Wolff RAEditors: Canellos GP, Schnipper L.UpToDate, Waltham, MA2010
• UpToDate online 
  Chapter: Treatment of small bowel neoplasms-II 
  Cusack JC, Overman MJ, Wolff RAEditors: Canellos GP, Schnipper L.UpToDate, Waltham, MA2010
• UpToDate online 
  Chapter: Epidemiology, clinical features, and types of small bowel neoplasms-I 
  Cusack JC, Overman MJ, Wolff RAEditors: Canellos GP, Schnipper L.UpToDate, Waltham, MA2009
• UpToDate online 
  Chapter: Treatment of small bowel neoplasms-I 
  Cusack JC, Overman MJ, Wolff RAEditors: Canellos GP, Schnipper L.UpToDate, Waltham, MA2009
• Therapeutic approaches to localized rectal cancer: current colorectal cancer reports 
  Chapter: Advances in the surgical technique for primary rectal cancer 
  Page 43.0 - 50.0Regenbogen S, Cusack JCEditors: Ajani J.Current Science, Bangalore, India2005
• Cancer drug discovery and development: the oncogenomics handbook 
  Chapter: Targeting inducible chemotherapy resistance mechanisms in colon cancer 
  Ljungman D, Cusack JCEditors: Shimkets RA, LaRochelle WJ.Humana Press, Totowa, NJ2005
• Unbound surgery 
  Chapter: Gallbladder cancer 
  Flannery J, Cusack JCEditors: Pappas TN, Purcell GP.Unbound Medicine, Charlottesville, VA2004
• Cancer drug discovery and development: proteasome inhibitors in cancer therapy 
  Chapter: Proteasome-dependent regulation of NF-kappaB activation: molecular targeting of chemotherapy resistance 
  Page 131.0 - 143.0Cusack JCEditors: Adams J.Humana Press, Totowa, NJ2004
• UpToDate online 
  Chapter: Epidemiology, clinical features, and types of small bowel neoplasms 
  Cusack JCEditors: Canellos GP, Schnipper L.UpToDate, Waltham, MA2003
• UpToDate online 
  Chapter: Diagnosis and management of small bowel neoplasms 
  Cusack JCEditors: Canellos GP, Schnipper L.UpToDate, Waltham, MA2003
• Surgery: scientific basis and current practice 
  Chapter: Gene therapy 
  Tanabe K, Cusack JCEditors: Norton, Bollinger, Chang, Lowry, Mulvihill, Pass, Thompson.Springer Verlag, New York2000
• Surgical research 
  Chapter: Cancer gene therapy 
  Page 457.0 - 490.0Tanabe K, Cusack JCEditors: Wilmore D, Souba C.Academic Press, New York2000
• The M. D. Anderson surgical oncology handbook 
  Chapter: Small bowel malignancies and carcinoid tumors 
  Robinson EK, Cusack JC, Tyler DSEditors: Feig B.Lippincott Williams and Wilkins, New YorkEdition 2nd,1999
• Malignant liver tumors: current and emerging therapies 
  Chapter: Induction of apoptosis in primary and secondary hepatic tumors 
  Cusack JCEditors: Clavien, P-A.Blackwell Science, Malden, MA1999
• The M. D. Anderson handbook of surgical oncology 
  Chapter: Small bowel malignancies and carcinoid tumors 
  Cusack JC, Tyler DEditors: Berger D, Feig B, Fuhrman G.Little Brown, Boston1995
• The M. D. Anderson handbook of surgical oncology 
  Chapter: Periampullary malignancies 
  Cusack JCEditors: Berger D, Feig B, Fuhrman G.Little Brown, Boston1995
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Abstracts/Posters

• Current Referral Patterns for Cytoreductive Surgery and HIPEC in the Management of Appendiceal Neoplasms
  Cintolo-Gonzalez J, Williams R, Chan C, DePeralta D, Haynes, AB, Cusack J, International Symposium on Regional Cancer Therapies, 1/1/2017
• Comparison of Surgical Outcomes Between Commission on Cancer-Accredited vs. Non-Accredited Hospitals in Gastrointestinal Surgical Oncology
  Fong ZV, Chang DC, Stapleton SS, Jin G, Haynes AB, Mullen JT, Cusack JC, Boland GM, Lillemoe KD, Tanabe KK, Qadan M, SSO, 1/1/2017
• Long Term Outcomes and Toxicity of Large Cohort of Anal Cancer Pts treated Per RTOG 0529
  Mitra D, Hong T, Rose B, Drapek L, Blaszkowsky L, Allen J, Kwak E, Murphy J, Ryan D, Cusack J, Wo J, ASTRO, 1/1/2016
• Detecting peritoneal surface malignancies with cathepsin-based fluorescent imaging system
  Chan CHF, Liesenfeld Lukas, Ferreiro-Neira I, Cusack JC, SSO, 1/1/2016
• Treatment of Peritoneal Carcinomatosis of Colorectal Origin: the Role of Debulking Surgery
  Cusack JC, ASCO, Chicago, IL, 1/1/2015
• Principles of Surgical Oncology
  Cusack JC, Mbarara University of Science and Technology, Mbarara, Uganda, 1/1/2015
• IDH1 Mutation in Small Bowel Adenocarcinoma
  Chan CHF, Williams RT, Dias-Santagata D, Iafrate AJ, Murphy JE, Ryan DP, Cusack JC, SSO, 1/1/2015
• Increase of nuclear survivin by CRM1 inhibition enhances radiation response in preclinical models of rectal cancer
  Ferreiro-Neira I, Torres N, Landesman Y, Senapedis W, Shachac S, Cusack JC, MGH, 1/1/2015
• Optimal sequencing schedules for combining BRAF inhibition with BCL2 inhibition
  Schalck A, Frederick DT, Hammond M, Ferreiro-Neira, I, Cooper ZA, Cusack J, Lawrence DP, Flaherty KT, Wargo JA, Sullivan RJ, AACR/EORTC/NCI Molecular Targets and Cancer Therapeutics Meeting, 1/1/2014
• Principles of Surgical Oncology – Operating in a Multi-Disciplinary Cancer Program
  Cusack JC, Meeting the Challenge of Cancer in Botswana, Gaborone, Botswana, 1/1/2014
• Surgery within the Context of a Multi-Disciplinary Cancer Program
  Cusack JC, Global Cancer Care: Challenges and Opportunities, Students for GO! and the Global Oncology (GO!) Initiative, Boston, MA, 1/1/2014
• Preoperative Ureteral stenting For patients undergoing cytoreductive surgery and heated intraperitoneal chemotherapy
  Chan CHF, Fong ZV, McGovern FJ, Cusack JC, 9th International Symposium on Regional Cancer Therapies, 1/1/2014
• Surgical resection and intraoperative radiation therapy for locally recurrent rectal carcinoma
  Furfaro D, Fong ZV, Shellito PC, Berger DL, Szymonifka J, Wo JY, Hong TS, Cusack JC, ASCO, 1/1/2014
• Outcomes with Full Dose Re-irradiation with Curative Intent for Secondary Anorectal Cancers following Prostatic Radiotherapy
  Tanguturi ST, Wo JY, Zietman AL, Blaszkowsky L, Kwak E, Berger D, Cusack J, Hong T, ASTRO, 1/1/2014
• Clinical and Treatment Factors Associated with Vaginal Stenosis after Definitive Chemoradiation for Anal Cancer
  Mirabeau-Beale KL, Hong TS, Ancukiewicz M, Ryan DP, Blaszkowsky L, Drapek L, Cusack JC, Kachnic LA, Wo JY, ASTRO, 1/1/2013
• Selective inhibition of nuclear export (SINE) using a CRM1/XPO1 antagonist overcomes resistance to CPT-11 in colon cancer in preclinical model
  Chung HW, Salas Fragomeni,RA, Shacham S, Kauffman M, Cusack JC, ASCO GI, 1/1/2013
• Mutational Analysis of Locally Advanced Rectal Cancer and Response to Neoadjuvant Chemoradiation
  Russo AL, Ryan DP, Borger DR, Wo JY, Szymonifka J, Kwak EL, Blaszkowsky LS, Clark JW, Allen JN, Zhu AX, Berger DL, Cusack JC, Haigis KM, Hong TS, ASCO GI, 1/1/2013
• Providing Multidisciplinary Cancer Care in Rwanda: What is the Standard of Care?
  Cusack JC, 6th Annual Meeting of the Alliance for Surgery and Anesthesia Presence (ASAP), Durham, NC, 1/1/2013
• Current and Emerging Strategies for Locally Recurrent Rectal Cancer
  Cusack JC, Tufts Medical Center, Surgery Grand Rounds, Boston, MA, 1/1/2013
• XPO1 and BRAF inhibition synergize and modulate pRb, Survivin and ERK in Melanoma
  Salas Fragomeni RA, Chung H-W, Shacham S, Kauffman M, Cusack JC, SSO, 1/1/2013
• Management of Locally Advanced Rectal Cancer
  Cusack JC, Hospital Grand Rounds, Butaro Hospital, Rwanda, 1/1/2013
• Emerging Trends in Management of Locally Advanced Rectal Cancer after Neoadjuvant Treatment
  Cusack JC, 4th International Symposium on Cancer: Emerging Trends in the Management of Pelvic Malignancies, St. Luke’s Cancer Institute, Manila, Philippines, 1/1/2012
• Current and Emerging Strategies for Locally Recurrent Rectal Cancer
  Cusack JC, 4th International Symposium on Cancer: Emerging Trends in the Management of Pelvic Malignancies, St. Luke’s Cancer Institute, Manila, Philippines, 1/1/2012
• Potent anticancer activity against both BRAF-mutant and BRAF wild-type melanoma cell lines using a novel CRM1 nuclear export inhibitor
  Salas Fragomeni RA, Chung H-W, Shacham S, Kauffman M, Cusack JC, AACR, 1/1/2012
• Merkel Cell Carcinoma: the 30-Year Experience from a Single Institution
  Santamaria, JA, Boland, GM, Yeap, BY, Nardi, V, Dias-Santagata D, Cusack JC, SSO, 1/1/2012
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Lectures

• Appendiceal Cancer:Should a non-HIPEC surgeon ever tackle it and how? 
  Boston, MA - 1/1/2016
• Rectal cancer: what is the minimum acceptable distal margin? 
  Boston, MA - 1/1/2016
• Does my patient truly need a palliative colectomy for cancer? 
  Boston, MA - 1/1/2016
• Ruptured appendiceal neoplasm: now what? 
  Boston, MA - 1/1/2016
• What is involved in setting up a HIPEC program? 
  Boston, MA - 1/1/2016
• Preclinical Evaluation of Cathepsin-based Fluorescent Imaging System for Cytoreductive Surgery 
  Chandler, AZ - 1/1/2016
• Intrauterine Metastases of Appendiceal Tumors Impact Cytoreduction 
  Chandler, AZ - 1/1/2016
• MGH Global Surgery Initiative-Working together to improve surgical care in resource-limited settings 
  Boston, MA - 1/1/2015
• CRS/HIPEC for Mucinous tumors 
  Boston, MA - 1/1/2015
• Total mesocolic excision for colon cancer: should we do it? 
  Boston, MA - 1/1/2015
• Desmoplastic Small Round Cell Tumor of the Peritoneal Cavity in a 32-Year Old Man 
  Clearwater Beach, Florida - 1/1/2015
• The Role of Cytoreductive Surgery and HIPEC in Managing Peritoneal Carcinomatosis from Colorectal Cancer 
  Boston, MA, 2014; Danvers, MA, 2014 - 1/1/2014
• Hereditary Colon Cancer 
  1/1/2014
• Cytoreduction and HIPEC for Ovarian Cancer 
  Boston, MA - 1/1/2014
• MGH Global Surgery Initiative (GSI) Expanding Global Surgery Opportunities (Research, Education, Patient Care) for Residents and Faculty 
  Boston, MA - 1/1/2014
• Combined systemic and regional therapy in a young adult with peritoneal carcinomatosis from small bowel adenocarcinoma 
  1/1/2014
• The Role of Cytoreduction and HIPEC in the Management of Peritoneal Carcinomatosis from Colorectal Cancer 
  Boston, MA - 1/1/2013
• Anal Condyloma and Dysplasia: Why should we screen high-risk patients and how? 
  Boston, MA - 1/1/2013
• High Resolution Anoscopy to Evaluate Anal Fissure or Condyloma in a HIV Male: Yes, You Can Do It Too! 
  Boston, MA - 1/1/2013
• Extrasphincteric Abdominoperineal Resection: Should We Do This More? 
  Boston, MA - 1/1/2013
• Surgical Debulking and HIPEC for the Treatment of Appendiceal and Colorectal Neoplasms 
  1/1/2013
• Status of Surgical Oncology in Rwanda 
  Boston, MA - 1/1/2013
• Role of Cytoreductive Surgery and HIPEC in Managing Peritoneal Carcinomatosis from Colorectal Cancer 
  Boston, MA - 1/1/2013
• High Risk Behaviors that Lead to Malignancy Later in Life 
  Danvers, MA - 1/1/2012
• Treatment of Anal Condyloma and Dysplasia: Why Every Surgeon Must Learn How to Do High Resolution Anoscopy 
  Boston, MA - 1/1/2012
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Other

• The multidisciplinary gastrointestinal oncology program at the University of North Carolina at Chapel Hill 
  Cusack JC, Brochure, gastrointestinal cancer program
  1/1/1999
• Update on the 1998 American College of Surgeons’ young surgeon representatives meeting 
  Cusack JC, Newsletter, American College of Surgeons North Carolina Chapter
  1/1/1998
• Unsuspected tumor invasion during pancreaticoduodenectomy 
  Cusack JC, Evans DB, Clinical communication, Chirurgia International
  1/1/1995
• Epidemiology, clinical features, and types of small bowel neoplasms 
  Cusack JC, Overman MJ
  http://www.uptodate.com/contents/epidemiology-clinical-features-and-types-of-small-bowel-neoplasms
  UpToDate, Wolters Kluwer Health - 2012-07-27
• Diagnosis and staging of small bowel neoplasms 
  Cusack JC, Overman MJ
  http://www.uptodate.com/contents/diagnosis-and-staging-of-small-bowel-neoplasms
  UpToDate, Wolters Kluwer Health - 2013-01-16
• Treatment of small bowel neoplasms 
  Cusack JC, Overman MJ
  http://www.uptodate.com/contents/treatment-of-small-bowel-neoplasms
  UpToDate, Wolters Kluwer Health - 2012-11-01
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