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Office
11100 Euclid Ave
Cleveland, OH 44106Phone+1 216-844-3800Fax+1 216-286-6341
Summary
- I am Emeritus Professor of Medicine at Case Western Reserve University and Emeritus Director of the William T Dahms MD Clinical Research Unit and Clinical Hypertension Program at University Hospitals Case Medical Center. I received both my MD and PhD (Pharmacology) from the University of Pittsburgh and Internal Medicine residency at the University of Michigan. I have over 300 publications and served on many national and international advisory panels.
My research experience includes having had a major or leadership role in nearly all of the major clinical outcome trials conducted in Black populations over the past three decades. These include Vice Chair of the Steering Committee for the NIH-sponsored African American Study of Kidney Disease in Hypertensives Trial (AASK) and serving as first author of its primary results paper. I also served as Chair of the Executive Committee and Vice Chair of the Steering Committee for the largest study of hypertension treatment ever completed, (ALLHAT with more than 42,000 participants and more than 15,000 Blacks) and lead author on the primary results paper. In addition to identifying the most effect medications to prevent the complications of hypertension, this study demonstrated the feasibility and importance of recruiting and retaining large numbers of minorities into clinical trials. Most recently, I led the NEJM paper reporting the results of the SPRINT trial with over 9,200 participants) documenting the benefit of treating patients to a SBP of < 120 mmHg compared treatment to the usually recommended < 140 mmHg in reducing cardiovascular events and mortality. I was selected as an author on the last four US national hypertension guidelines including the most recent guideline which redefined the blood pressure level for the diagnosis and treatment of hypertension.
Education & Training
- University of MichiganResidency, Internal Medicine, 1977 - 1980
- University of Pittsburgh School of MedicinePhD, Pharmacology, 1971 - 1977
- University of Pittsburgh School of MedicineClass of 1976
Certifications & Licensure
- OH State Medical License 1990 - 2025
- American Board of Internal Medicine Internal Medicine
Clinical Trials
- Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) Start of enrollment: 1993 Aug 01
- African American Study of Kidney Disease and Hypertension ABPM Pilot Study Start of enrollment: 2007 Nov 01
- Systolic Blood Pressure Intervention Trial Start of enrollment: 2010 Oct 01
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Publications & Presentations
PubMed
- Assessing Priorities in a Statewide Cardiovascular and Diabetes Health Collaborative Based on the Results of a Needs Assessment: Cross-Sectional Survey Study.Elizabeth A Beverly, Sarah Koopman-Gonzalez, Jackson Wright, Kathleen Dungan, Harini Pallerla
JMIR Formative Research. 2024-04-12 - 1 citationsAmbient Air Pollution and Pulse Wave Velocity in Patients With Hypertension Treated With Intensive Versus Standard Blood Pressure Control.Sadeer G Al-Kindi, Robert D Brook, Mirela Dobre, Mahboob Rahman, Jackson T Wright
Hypertension. 2022-12-01 - 1 citationsIntensive Versus Standard Blood Pressure Lowering and Days Free of Cardiovascular Events and Serious Adverse Events: a Post Hoc Analysis of Systolic Blood Pressure Int...Dae Hyun Kim, Curtis Tatsuoka, Zhengyi Chen, Jackson T Wright Jr, Michelle C Odden
Journal of General Internal Medicine. 2022-11-01
Press Mentions
- Excess BP Lowering down CV Risk in Pollution Exposed PatientsFebruary 1st, 2021
- Recruiting Black Clevelanders for COVID-19 Trials Is an Uphill BattleOctober 29th, 2020
- Black Physicians Help Build Trust After Decades of Community SkepticismOctober 28th, 2020
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Grant Support
- Research CoreNational Center On Minority Health And Health Disparities2007–2011
- AASK Colhort StudyNational Institute Of Diabetes And Digestive And Kidney Diseases2003–2007
- Genetics Of SALT Sensitive HypertensionNational Center For Research Resources2004–2006
- African American Study Of Kidney Disease And Hypertension CohortNational Center For Research Resources2004–2006
- Genetics Of SALT Sensitivity In African AmericansNational Center For Research Resources2004–2005
- Genetics Of SALT Sensitivity In African AmericansNational Heart, Lung, And Blood Institute2002–2004
- Cohort Study Of Chronic Renal InsufficiencyNational Institute Of Diabetes And Digestive And Kidney Diseases2001–2002
- African American Study Of Kidney Disease In HypertensionNational Institute Of Diabetes And Digestive And Kidney Diseases1994–2002
- Minortity Initiative In Medical Science TrainingNational Center For Research Resources1994
- Trial Of Antihypertensive Therapy On RenoprotectionNational Institute Of Diabetes And Digestive And Kidney Diseases1992–1994
- Genetics In Hypertension In African AmericansNational Center For Research Resources1993
- Cs-622 Duration Of Action In Mild To Moderate Essential HypertensionNational Center For Research Resources1992
- Minority Hypertension Research Development Summer PrograNational Heart, Lung, And Blood Institute1985–1986
Professional Memberships
- Fellow
- Fellow
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