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Office
600 Highland Ave
H4414 CSC
Madison, WI 53792Phone+1 608-262-1603Fax+1 608-263-0440
Education & Training
- University of Iowa Hospitals and ClinicsFellowship, Pediatric Cardiology, 2000 - 2003
- University of Iowa Hospitals and ClinicsResidency, Pediatrics, 1997 - 2000
- State University of New York Downstate Medical Center College of MedicineClass of 1997
Certifications & Licensure
- IL State Medical License 2013 - 2026
- MI State Medical License 2010 - 2026
- WI State Medical License 2007 - 2025
- IA State Medical License 1997 - 2016
- PA State Medical License 2004 - 2008
- American Board of Pediatrics Pediatric Cardiology
Publications & Presentations
PubMed
- 22 citationsTranscriptome Analysis of Cardiac Hypertrophic Growth in MYBPC3-Null Mice Suggests Early Responders in Hypertrophic RemodelingEmily F. Farrell, Annie E. Armstrong, Adrian C. Grimes, Francisco J. Naya, Willem J. de Lange
Frontiers in Physiology. 2018-10-25 - 58 citationsDistinct hypertrophic cardiomyopathy genotypes result in convergent sarcomeric proteoform profiles revealed by top-down proteomics.Trisha Tucholski, Wenxuan Cai, Zachery R. Gregorich, Elizabeth F. Bayne, Stanford D. Mitchell
Proceedings of the National Academy of Sciences of the United States of America. 2020-10-06 - 25 citationsE258K HCM-causing mutation in cardiac MyBP-C reduces contractile force and accelerates twitch kinetics by disrupting the cMyBP-C and myosin S2 interaction.Willem J. de Lange, Adrian C. Grimes, Laura F. Hegge, Alexander M. Spring, Taylor M. Brost
The Journal of General Physiology. 2013-09-01
Grant Support
- Modeling cMyBP-C Hypertrophic CardiomyopathyNational Heart, Lung, and Blood Institute2011–2015
Professional Memberships
- Member
- Fellow
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