ItaloBiaggioniMD

Internal Medicine • Nashville, TN

Clinical Pharmacology

Professor, Medicine, Vanderbilt University School of Medicine

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Office
3601 21st Ave S
Nashville, TN 37232
Phone+1 615-936-2000

Education & Training

Cayetano Heredia UniversityClass of 1980

Certifications & Licensure

TN State Medical License 1987 - 2026
AL State Medical License 2020 - 2020

Clinical Trials

Nitric Oxide and the Autonomic Nervous System Start of enrollment: 2002 Aug 01
Completed
Not Applicable
AMP as a Better Delivery System of Adenosine Start of enrollment: 2003 Oct 01
Terminated
Phase 1
The Autonomic Nervous System and Obesity Start of enrollment: 2003 Apr 01
Completed
Phase 1
Treatment of Orthostatic Hypotension in Autonomic Failure Start of enrollment: 2002 Mar 01
Completed
Phase 1
Treatment of Supine Hypertension in Autonomic Failure Start of enrollment: 2001 Jan 01
Completed
Phase 1
Autonomic Nervous System and Chronic Fatigue Syndrome Start of enrollment: 2007 Apr 01
Completed
Phase 1
Role of Adenosine in the Release of VEGF and Cytokines Start of enrollment: 2007 Jun 01
Terminated
Phase 1
The Autonomic Nervous System and the Metabolic Syndrome Start of enrollment: 2008 Aug 01
Completed
Not Applicable
Treatment of Orthostatic Hypotension Start of enrollment: 2004 Jan 01
Terminated
Phase 2, Phase 3
Pathophysiology of Orthostatic Intolerance Start of enrollment: 1996 Dec 01
Recruiting
Not Applicable
Nebivolol in the Supine Hypertension of Autonomic Failure Start of enrollment: 2010 Jan 01
Completed
Not Applicable
The Role of Endothelin in the Supine Hypertension of Autonomic Failure Start of enrollment: 2010 May 01
Withdrawn
Phase 1
Pathophysiology of Cardiometabolic Risk Factors in African Americans Start of enrollment: 2010 Jan 01
Completed
Phase 1
Autonomic Nervous System and Nitric Oxide Interactions Start of enrollment: 2010 Jun 01
Completed
Phase 1
Contribution of Angiotensin II to Supine Hypertension in Autonomic Failure Start of enrollment: 2011 Mar 01
Terminated
Phase 1
Norepinephrine Transporter Blockade as a Pathological Biomarker in Neurogenic Orthostatic Hypotension Start of enrollment: 2011 Mar 01
Completed
Magnetic Resonance Spectroscopy in Autonomic Failure Start of enrollment: 2012 Jul 01
Terminated
Effect of Ticagrelor vs. Dipyridamole on Adenosine Uptake Start of enrollment: 2012 Aug 01
Completed
Phase 1
High Sodium Diet and External Abdominal Compression in POTS Start of enrollment: 2012 Dec 01
Terminated
Phase 1
Modafinil and Cognitive Function in POTS Start of enrollment: 2014 Oct 01
Active, not recruiting
Early Phase 1
Cardiovascular Effects of Angiotensin (1-7) in Essential Hypertension Start of enrollment: 2015 Jan 01
Terminated
Phase 1
Local Heat Stress in Autonomic Failure Patients With Supine Hypertension Start of enrollment: 2015 Apr 01
Completed
Not Applicable
Role of Sympathetic Activity and Splanchnic Capacitance in Hypertension Start of enrollment: 2015 Apr 01
Active, not recruiting
Phase 1
Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic Failure Start of enrollment: 2015 Apr 01
Recruiting
Phase 1
TD-9855 Phase 2 in Neurogenic Orthostatic Hypotension (nOH) Start of enrollment: 2017 Sep 09
Completed
Phase 2
Reduction in Splanchnic Capacitance Contributes to Sympathetically Dependent Hypertension in Autonomic Start of enrollment: 2016 Apr 01
Active, not recruiting
Phase 1
Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure Start of enrollment: 2016 Sep 01
Recruiting
Phase 1
Autonomic Blockade and Endogenous Glucose Production Start of enrollment: 2017 Apr 17
Withdrawn
Phase 1
Overnight Trials With Heat Stress in Autonomic Failure Patients With Supine Hypertension Start of enrollment: 2017 Jan 30
Recruiting
Not Applicable
Vagal Stimulation in POTS Start of enrollment: 2017 Sep 30
Active, not recruiting
Phase 1
Treatment of Supine Hypertension in Autonomic Failure (CPAP) Start of enrollment: 2017 Sep 21
Recruiting
Not Applicable
Role of Sympathetic Vasoconstriction on Insulin-Mediated Microvascular Recruitment and Glucose Uptake in Obesity Start of enrollment: 2017 Oct 24
Active, not recruiting
Phase 1
Sympathetic Mechanisms in the Cardiovascular and Metabolic Alterations of Obesity Start of enrollment: 2021 Feb 23
Suspended
Phase 1
Effect of Raised Head of the Bed on Lying Blood Pressure in Autonomic Failure Start of enrollment: 2020 Aug 21
Recruiting
Not Applicable
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Publications & Presentations

PubMed

Atomoxetine on neurogenic orthostatic hypotension: a randomized, double-blind, placebo-controlled crossover trial.
Naome Mwesigwa, Patricio Millar Vernetti, Annet Kirabo, Bonnie Black, Tan Ding
Clinical Autonomic Research. 2024-12-01
Blood volume deficit in postural orthostatic tachycardia syndrome assessed by semiautomated carbon monoxide rebreathing.
Surat Kulapatana, Vasile Urechie, Stefano Rigo, Abigail Mohr, Yuliya A Vance
Clinical Autonomic Research. 2024-11-30
Disentangling the phenotypic patterns of hypertension and chronic hypotension.
William W Stead, Adam Lewis, Nunzia B Giuse, Annette M Williams, Italo Biaggioni
Journal of Biomedical Informatics. 2024-11-01

Press Mentions

Protect Your Blood Pressure: Balancing Sitting and Standing at WorkDecember 10th, 2024
Standing All Day at Work May Be Bad for Blood Pressure, Study SaysDecember 9th, 2024
Long-Term Effects of COVID-19 on Heart, Cardiovascular System Under Study After AHA GrantApril 16th, 2022
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Grant Support

Cardiovascular Regulations Autonomic/Metabolic MechanismsNational Heart, Lung, And Blood Institute2012
Clinical CoreNational Heart, Lung, And Blood Institute2007–2012
Cardiovascular Reguations: Autonomic/Metbolic MechanismsNational Heart, Lung, And Blood Institute2010–2011
Project 2 - Autonomic RARE Diseases Clinical Research ConsortiumNational Institute Of Neurological Disorders And Stroke2009–2011
Autonomic Nervous System In Chronic Fatigue SyndromeNational Institute Of Neurological Disorders And Stroke2006–2009
Oxide And Autonomic MechanismsNational Center For Research Resources2005–2008
The Autonomic Nervous System And ObesityNational Center For Research Resources2004–2008
Adenosine And Nitric Oxide Interaction In Vascular RegulationNational Center For Research Resources2004–2008
Etiology And Pathophysiology Of Autonomic FailureNational Center For Research Resources1993–2008
Cardiovascular Regulations: Autonomic/Metabolic MechanismsNational Heart, Lung, And Blood Institute2007
Role Of Adenosine And Nitric Oxide On The Mechanism Of Action Of AggrenoxNational Center For Research Resources2004
Oxide And Autonomic Mechanisms .National Center For Research Resources2004
Adenosine And Nitric Oxide DeficiencyNational Heart, Lung, And Blood Institute2001–2004
Pharmacologic Probes In Neurally-Mediated SyncopeNational Heart, Lung, And Blood Institute2002–2003
Nitric Oxide In Autonomic FailureNational Center For Research Resources2000–2002
Renal Denervation In Orthostatic IntoleranceNational Center For Research Resources1999–2002
Adenosine In Exercise Pressor ReflexNational Center For Research Resources1998–2002
Adenosine A2B Receptors In Human MAST CellsNational Center For Research Resources1998–2002
Core--AnalyticalNational Heart, Lung, And Blood Institute1997–2002
Cardiovascular Regulation--Autonomic/Metabolic MechanismsNational Heart, Lung, And Blood Institute1997–2002
Cardiovascular Effects Of CocaineNational Center For Research Resources1993–1995
Adenosine And Neural Mechanisms Of Cardiovascular ControlNational Heart, Lung, And Blood Institute1991–1994
Effect Of ACE Inhibition On Sympathetic ActivityNational Center For Research Resources1992
Circulatory Control In Chronic Hypotensive StatesNational Center For Research Resources1992
Autonomic Dysfuntion--Taxonomy And TherapyNational Center For Research Resources1990–1991
DOPA As An Endogenous NeurohormoneNational Center For Research Resources1990
Adenosine And MAST Cell ActivationNational Center For Research Resources1989
Determinants Of The Hemodynamic Effects Of AdenosineNational Center For Research Resources1987–1989