IssamA.AwadMD

PubMed

• 261 citations
  Thrombolytic removal of intraventricular haemorrhage in treatment of severe stroke: results of the randomised, multicentre, multiregion, placebo-controlled CLEAR III t...
  Daniel F. Hanley, Karen Lane, Nichol McBee, Wendy C. Ziai, Stanley Tuhrim
  Lancet. 2017-02-11
• 22 citations
  A Brain-Targeted Orally Available ROCK2 Inhibitor Benefits Mild and Aggressive Cavernous Angioma Disease.
  Lisa McKerracher, Robert Shenkar, Matthew D. Abbinanti, Ying Cao, Amy Peiper
  Translational Stroke Research. 2020-06-01
• 257 citations
  Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity.
  Rebecca A. Stockton, Robert Shenkar, Issam A. Awad, Mark H. Ginsberg
  The Journal of Experimental Medicine. 2010-04-12

Journal Articles

• Atorvastatin Treatment of Cavernous Angiomas with Symptomatic Hemorrhage Exploratory Proof of Concept (AT CASH EPOC) Trial  
  Amy L Akers, Kevin J Whitehead, Gregory A Christoforidis, Daniel F Hanley, Kelly D Flemming, Sean P Polster, James K Liao, Matthew Sorrentino, Cornelia Lee, Issam A Aw..., Neurosurgery
• Cerebral Cavernous Malformations Form an Anticoagulant Vascular Domain  
  Angela Pham, Mark H Ginsberg, Sean Polster, Issam A Awad, Blood
• Dynamic permeability and quantitative susceptibility: Related imaging biomarkers in cerebral cavernous malformations  
  Mikati AG, Tan H, Shenkar R, Li L, Zhang L, Guo X, Larsson HB, Shi C, Liu T, Wang Y, Shah A, Edelman RR, Christoforidis G, Awad IA, Stroke, 1/1/2014
• Evaluation of Iron Content in Human Cerebral Cavernous Malformation using Quantitative Susceptibility Mapping  
  Tan H, Liu T, Wu Y, Thacker J, Shenkar R, Mikati AG, Dykstra C, Wang Y, Prasad PV, Edelman RR*, Awad IA* (*=equal contributions), Investigative Radiology, 1/1/2014
• Lesions from patients with sporadic cerebral cavernous malformations harbor somatic mutations in the CCM genes: evidence for a common biochemical pathway for CCM Patho...  
  McDonald DA, Shi C, Shenkar R, Gallione CJ, Akers AL, Li S, De Castro N, Berg MJ, Corcoran DL, Awad IA, Marchuk DA, Hum Mol Genet, 1/1/2014
• Immune complex formation and in situ B-cell clonal expansion in human cerebral cavernous malformations  
  Shi C, Shenkar R, Kinloch A, Henderson SG, Shaaya M, Chong AS, Clark MR, Awad IA, J Neuroimmunol, 1/1/2014
• Spontaneous intracerebral and intraventricular hemorrhage: Advances in minimally invasive surgery and thrombolytic evacuation, and lessons learned from recent trials  
  Dey M, Stadnik A, Awad IA, Neurosurgery, 1/1/2014
• Guidelines for the prevention of stroke in women: a statement for healthcare professionals from the American Heart Association/American Stroke Asscociation  
  Bushnell C, McCullough LD, Awad IA, Chireau MV, Fedder WN, Furie KL, Howard VJ, Lichtman JH, Lisabeth LD, Piña IL, Reeves MJ, Rexrode KM, Saposnik G, Singh V, Towfighi..., Stroke, 1/1/2014
• Intensive care after elective craniotomy: “All politics is local” Invited “Perspective”  
  Awad IA, World Neurosurgery, 1/1/2014
• Minimally invasive surgery plus recombinant tissue-type plasminogen activator for intracerebral hemorrhage evacuation decreases perihematomal edema  
  Mould WA, Carhuapoma JR, Muschelli J, Lane K, Morgan TC, McBee NA, Bistran-Hall AJ, Ullman NL, Vespa P, Martin NA, Awad I, Zuccarello M, Hanley DF; MISTIE Investigators, Stroke, 1/1/2013
• The Modified Graeb Score: an enhanced tool for intraventricular hemorrhage measurement and prediction of functional outcome  
  Morgan TC, Dawson J, Spengler D, Lees KR, Aldrich C, Mishra NK, Lane K, Quinn TJ, Diener-West M, Weir CJ, Higgins P, Rafferty M, Kinsley K, Ziai W, Awad I, Walters MR,..., Stroke, 1/1/2013
• Hemorrhagic Stroke: Introduction  
  DF, Awad IA, Vespa PM, Martin NA. Zuccarello MA, Stroke, 1/1/2013
• Surgical trials in intracerebral hemorrhage  
  Vespa PM, Martin N, Zuccarello M, Awad I, Hanley DF, Stroke, 1/1/2013
• When blood tickles the brain: Where is the argument? Invited “Perspective” on seizures after subarachnoid hemorrhage  
  Awad IA, World Neurosurgery, 1/1/2013
• Drainage efficiency of dual versus single catheters in severe intraventricular hemorrhage  
  Hinson HE, Melnychuk E, Muschelli J, Hanley DD, Awad IA, Ziai WC, Neurocrit Care, 1/1/2012
• Occurrence and impact of intracranial pressure elevation during treatment of severe intraventricular hemorrhage  
  Ziai WC, Melnychuk E, Thompson CB, Awad IA, Lane K, Hanley DF, Crit Care Med, 1/1/2012
• Resolution of intraventricular hemorrhage varies by ventricular region and dose of intraventricular thrombolytic: the Clot Lysis: Evaluating Accelerated Resolution of ...  
  Webb AJ, Ullman NL, Mann S, Muschelli J, Awad IA, Hanley DF, Stroke, 1/1/2012
• External Ventricular Drainage for Intraventricular Hemorrhage  
  Dey M, Jaffe J, Stadnik A, Awad IA, Curr Neurol Neurosci Reports, 1/1/2012
• Thrombolytic evacuation of intracerebral and intraventricular hemorrhage  
  Dey M, Stadnik A, Awad IA, Curr Cardiol Reports, 1/1/2012
• Cavernous Malfromations: Editorial on Cerebral Cavernous Malformation Biology  
  Awad IA, J Neurosurg, 1/1/2012
• Conus medullaris spinal arteriovenous malformations Commentary  
  Awad IA, Bacon AD, Neurosurgery, 1/1/2012
• The riddle of association, causation and the prevention of subarachnoid haemorrhage  
  Awad IA, J Neurol Neurosurg Psychiatry, 1/1/2012
• Mean arterial pressure for maintaining patency of extracranial-to-intracranial bypass Commentary  
  Awad IA, Neurosurgery, 1/1/2012
• A novel mouse model of cerebral cavernous malformations based on the two-hit mutation hypothesis recapitulates the human disease  
  McDonald DA, Sehnkar R, Shi C, Stockton RA, Ackers AL, Kucherlapati MH, Kucherlapati R, Brainer J, Ginsberg MH, Awad IA*, Marchuk DA* (*=equal contributions), Hum Mol Genet, 1/1/2011
• MRI evaluation of cerebral cavernous malformations with susceptibility-weighted imaging  
  De Champfleur NM, Langoilois C, Ankenbrandt WJ, Le Bars E, Leroy MA, Duffau H, Bonafé A, Jaffe J, Awad IA*, Labauge P* (*=equal contributions), Neurosurgery, 1/1/2011
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Books/Book Chapters

• Neurovascular Surgical Techniques 
  Chapter: Future Microsurgical Technical Advances. Chapter 21 
  Page 373 - 379Dey M, Awad IAEditors: Jabbour PM.Jaypee Publisher2013
• Cavernous Malfromations of the Nervous System 
  Chapter: Surgical treatment of cavernous malformations associated with epilepsy. Chapter 12 
  Page 115 - 125Dey M and Awad IAEditors: Rigamonti D.Cambridge University Press2011
• Stroke: Pathophysiology, Diagnosis and Management 
  Chapter: Cerebral cavernous malformations and venous anomalies: Diagnosis, natural history and clinical management. Chapter 74 
  Page 1388 - 1397Eddelman CS, Batjer HH, Awad IAEditors: Mohr, Wolff, Grotta, Moskewitz, Mayberg, and von Kummer.ElsevierEdition 5th,2011
• Core Techniques in OPERATIVE NEUROSURGERY 
  Chapter: Open evacuation of intracerebral hematoma. 
  Page 239 - 243Awad IA, Dey M, Jaffe JEditors: Jandial, McCormick and Black.Elsevier2011
• Tumors of the Central Nervous system, Volume 3. 
  Chapter: Cerebral cavernous malformations: Advanced Magnetic Resonance Imaging. Chapter 15 
  Page 143 - 154Shenkar R, Ansari SA, Awad IAEditors: Hayat MA.Springer Publisher2011
• Core Techniques in OPERATIVE NEUROSURGERY 
  Chapter: Image-guided catheter evacuation and thrombolysis for intracerebral hematoma. 
  Page 244 - 252Awad IA, Dey M, Jaffe JEditors: Jandial, McCormick and Black.Elsevier2011
• Textbook of Epilepsy Surgery 
  Chapter: Epilepsy and Vascular Lesions. Chapter 118 
  Page 1098 - 1109Jabbour P, Awad IAEditors: Bingaman W, Najm I, Luders HO.Taylor and Francis Medical Books2008
• Neurosurgery Clinics of North America 
  Chapter: Current updates on perioperative management of intracerebral hemorrhage. 
  Page 401 - 414Hsieh P, Awad IA, Getch CC, Bendok BR, Rosenblatt SS, Batjer HB2008
• Cavernous Malformations of the Brain and Spinal Cord 
  Chapter: Molecular biology of cerebral cavernous malformations. 
  Page 11 - 21Jabbour P, Gault J, Shenkar R and Awad IAEditors: Lanzino G.Thieme, Inc.2007
• Intracranial Arteriovenous Malformations 
  Chapter: Pathology and Genetic Factors. 
  Page 21 - 30Moussa RF, Wong JH, Awad IAEditors: Stieg PE, Batjer HH and Samson DS.Informa Healthcare, Inc.2006
• Intracranial Arteriovenous Malformations 
  Chapter: Molecular Biology. 
  Page 469 - 481Gunel M, Awad IAEditors: Stieg PE, Batjer HH and Samson DS.Informa Healthcare, Inc.2006
• Complex Tumors and Vascular Lesions and Tumors 
  Chapter: Combined Endovascular and Surgical Treatment of Large Basilar Trunk Aneurysm in a Child. Chapter 18. 
  Jabbour P, Handler M, Huddle D, Awad IAEditors: Kobayashi S.Thieme (Publishers)2005
• Principles of Neurosurgery 
  Chapter: Cerebrovascular Occlusive Disease. Chapter 13. 
  Page 197 - 213Awad IAEditors: SS Rengashari and RG Ellenbogen.Elsevier MosbyEdition Seco,2004
• Textbook of Neurointensive Care 
  Chapter: Hemorrhagic Cerebrovascular Disease. 
  Page 155 - 181Jabbour P, Awad IA, Huddle DEditors: Layon AJ, Gabrielli A and Freidman WA.Saunders Publishers2004
• “Youman’s Neurological Surgery" 
  Chapter: Surgical Management of Supratentorial Cavernous Malformations. 
  Page 2305 - 2319Vives KP, Gunel M, Awad IAEditors: Winn HR.W.B. Saunders Publishers2004
• Management of Cerebral Aneurysms 
  Chapter: History of Aneurysm Management and Surgery. Chapter 1. 
  Page 1 - 9DiLuna ML, Lee S, Awad IA, Gunel MEditors: Le Roux PD, Winn HR, Newell DW.Saunders2003
• Walter E. Dandy: The Personal Side of a Premier Neurosurgeon 
  Editors: Marmaduke ME, Awad IA, and Laws EJ Jr..Lippincott Williams and Wilkins Publishers, New York, NY2002
• Neurosurgery Clinics of North America 
  Chapter: Carotid Endarterectomy Prevention Strategies and Complications Management. 
  Page 351 - 364Gunel M, Awad IAEditors: (Extracranial Cerebrovascular Disease, Harbaugh R ed).W.B. Saunders Publishers2000
• Fifty Years of Neurosurgery: The Golden Anniversary of the Congress of Neurological Surgeons 
  Chapter: Cerebrovascular Disease. 
  Page 141 - 165Lee S, Awad IAEditors: Barrow DL and Oyesiku N.Williams and Wilkins Publishers2000
• Vascular Malformations of the Central Nervous System 
  Editors: Awad IA, Jafar JJ, Rosenwasser R.Raven Press, Publishers, Philadelphia, PA1999
• Spinal Vascular Malformations 
  Chapter: Clinical Spectrum and Natural History of Spinal Vascular Malformations. 
  Page 45 - 55Keynar MY, Wecht DA and Awad IAEditors: Barrow DL and Awad IA.AANS Publishers1999
• Arteriovenous Malformations in Functional Areas of the Brain 
  Chapter: Vasculogenesis and Angiogenesis in Relation to Arteriovenous Malformations of the Brain. 
  Page 241 - 248Baev N, Wong J and Awad IAEditors: Yamada S..Futura Publishers1999
• Clinical Neurosurgery 
  Chapter: Protocols and Critical Pathways for Stroke Care. 
  Page 86 - 100Awad IA, Fayad PB, Abdulrauf SIWilliams and Wilkins, Publishers1999
• Principles of Neurosurgery 
  Chapter: Subarachnoid Hemorrhage. 
  Page 293 - 305Wecht DA and Awad IAEditors: Loftus C and Grossman R.Raven Press, PublishersEdition 2nd,1999
• Spinal Vascular Malformations 
  Chapter: Pathological Features of Spinal Vascular Malformations. 
  Page 9 - 21Wong JH, Kim J and Awad IAEditors: Barrow DL and Awad IA.AANS Publishers1999
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Abstracts/Posters

• “Permeability as a Biomarker of Cavernous Malformation.”
  Awad IA (senior author); Mikati, et al., Poster: Scientific presentations by Awad Lab Team, International Stroke Conference, San Diego, CA, 2/12/2014
• “Exceptional Aggressiveness of the CCM3 Phenotype.”
  Awad IA (senior author); Rebeiz, et al., Oral presentation: Scientific presentations by Awad Lab Team, International Stroke Conference, San Diego, CA, 2/12/2014
• “In Situ B-cell Clonal Expansion and Recombinant Antibody Construction in Human Cerebral Cavernous Malformations”
  Awad IA (senior author); Shi, et al., Poster: Scientific presentations by Awad Lab Team, International Stroke Conference, San Diego, CA, 2/12/2014
• “Characterizing Cerebral Cavernous Malformation with Quantitative Susceptbility Mapping”
  Awad IA (senior author); Tan, et al., Poster: Scientific presentations by Awad Lab Team, International Stroke Conference, San Diego, CA, 2/12/2014
• “Stabilizing Bleeding Prior to Acute Therapies for Spontaneous Intracerebral Hemorrhage”
  Awad IA-Senior co-aurthor (Principal Investigator); Ziai, et al.), Oral presentation: Scientific presentations by MISTIE and CLEAR Trial Teams, International Stroke Conference, San Diego, CA, 2/12/2014
• “MRI Demonstrates Sustained effect of Early Surgery on Peri-Hematomal Edema”
  Awad IA-Senior co-aurthor (Principal Investigator); Mould, et al., Poster: Scientific presentations by MISTIE and CLEAR Trial Teams, International Stroke Conference, San Diego, CA, 2/12/2014
• “Bleeding and Infection risk with External Ventricular Drainage and Thrombolysis for Intraventricular Hemorrhage”
  Awad IA-Senior co-aurthor (Principal Investigator); Dey, et al.), Poster: Scientific presentations by MISTIE and CLEAR Trial Teams, International Stroke Conference, San Diego, CA, 2/12/2014
• “Safety Endpoints and Thromboembolic Events for the First 250 Patients Enrolled in the Clot Lysis Evaluation of Accelerated Resolution of Intraventricular Hemorrhage T...
  Awad IA-Senior co-aurthor (Principal Investigator); Ziai, et al., Late-breaking oral abstract: Scientific presentations by MISTIE and CLEAR Trial Teams, International Stroke Conference, San Diego, CA, 2/12/2014
• Catheter placement and surgical training in the Minimally Invasive surgery Plus rt-PA for Intracerebral Hemorrhage Evacuation Trial.
  Ullman NL, Muscelli J, Li M, Morgan TC, Awad IA, Zuccarello M, Hanley DF (For the MISTIE Trial Investigators), International Stroke Conference, Honolulu, HI, 2/6/2013
• Novel model of cerebral cavernous malformation based on two hit hypothesis recapitulates human disease.
  McDonald R, Shenkar R, Shi C, Marchuk D and Awad IA, Annual Investigators Workshop of the Angioma Alliance, Washington, DC, 11/1/2010
• “Improving magnetic resonance imaging of cerebral cavernous malformations in men and mice”.
  Awad IA, Labauge P, Shenkar R, Wyrwicz A, Marchuk D, Annual Investigators Workshop of the Angioma Alliance, Santa Fe, NM, 11/12/2009
• “Double hits and the pathobiology of cerebral cavernous malformations”.
  Awad IA, Marchuk D, Ginsberg M, Annual Meeting of the American Academy of Neurological Surgeons, Palm Beach, FL, 11/4/2009
• “Immune response in Human Cerebral Cavernous Malformations: Oligoclonality and correlation with Clinical Manifestations”.
  Shenkar R, Shi C, Awad IA, Annual Meeting, Congress of Neurological Surgeons, Orlando, FL, 9/20/2008
• Genomics of Human Intracranial Aneurysm: A Gene Chip Study”.
  Shi C, Awad IA, Jafari N, Lin S, Du P, Hage ZA, Shenkar R, Getch CC, Bredel M, Batjer HH, Bendok BB, Annual Meeting, Congress of Neurological Surgeons, Orlando, FL, 9/20/2008
• “Science Versus Engineering Approach to Neurosurgical Research: Case Study and Implications for Team assembly and Program Development”.
  Awad IA, Batjer HB, Glucksberg M, Annual Meeting, American Academy of Neurological Surgery, Sedona, AZ, 9/10/2008
• Genetic profile of human intracranial aneurysms: A study using microarray.
  Bendok B, Shi C, Shenkar R, Hage ZA, Jafari N, Lin S, Du P, Getch CC, Batjer HH, and Awad IA, International Stroke Conference, New Orleans, LA, 2/20/2008
• Inflammatory cell infiltration in cerebral cavernous malformations and lesion phenotype and clinical manifestations.
  Shenkar R, Raja H, Du H, Shi C, Batjer HH and Awad IA, International Stroke Conference, New Orleans, LA, 2/20/2008
• Biallelic somatic and germ line KRIT1 mutations in the vascular endothelial cells of cerebral cavernous malformations.
  Gault J, Awad IA, Recksiek P, et al., International Stroke Conference, San Francisco, CA, 2/7/2007
• Advanced imaging in cerebral cavernous malformations: A platform for molecular imaging technology development and validation.
  Shenkar R, Venkatsubramanian P, Zhao J-C, Kohlmeier E, Cilliers R, Kung M, Marchuk D, Kung H, Wyrwicz A, Meade T, Awad IA, Fifth Annual Meeting of the Scoiety of Molecular Imaging, Waikoloa Village, HI, 8/30/2006
• Molecular biology and genetics of Krit1, the gene mutated in cerebral cavernous malformations 1.
  Gunel M, Diluna M, Shin D, et al., Awad IA, Lifton R, 70th Annual Meeting of the American Association of Neurological Surgeons, Toronto, Ontario, Canada, 4/21/2001
• Patterns of functional MR activation: A classification of plasticity.
  Carpentier AC, Constable RT, Schlosser MJ, Piepmeier JM, Spencer DD and Awad IA, 50th Annual meeting of the Congress of Neurological Surgeons, San Antonio, TX, 9/23/2000
• Endovascular Adjunct in Microsurgical Treatment of Paraclinoid Aneurysms.
  Ng PY, Huddle D, Gunel M, Awad IA, Annual Joint Meeting of the Cerebrovascular Section of the AANS and CNS and The American Society of Therapeutic and Interventional Neuroradiology, New Orleans, LA, 2/6/2000
• “Stereotactic CT Guided Aspiration and Thrombolysis of Intracerebral Hematoma: Protocol and Preliminary Experience”.
  Wong J, Montes J, Fayad PB, Awad IA, The 49th Annual Meeting of the Congress of Neurological Surgeons, Boston, MA, 10/29/1999
• “Does ASA Physical Status Predict Outcome and Resource Utilization in Treatment of Intracranial Aneurysms?”
  Sturaitis M, Rinne J, Lin Z, Awad IA, The 49th Annual Meeting of the Congress of Neurological Surgeons, Boston, MA, 10/29/1999
• “Etiologic Spectrum of Hemorrhagic Stroke in Young Patients: A Cohort Analysis in a Population Based Study”.
  Moussa R, Rinne J, Kernan W, Brass LM, Awad IA, The 49th Annual Meeting of the Congress of Neurological Surgeons, Boston, MA, 10/29/1999
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Lectures

• Surgical Trianing and Oversight for MISTIE Trial. 
  The George Institute for Global Health, Sydney, Australia - 9/18/2014
• “Virtue and Passion in Doctoring”. 
  Lebanese American University Chagoury School of Medicine- Rizk University Hospital, Beirut, Lebanon - 6/27/2014
• “Cavernous Angioma: Fundamentals of Clinical Care and Latest Research Advances”. 
  Toronto, Ontario, Canada - 6/7/2014
• Advances in Acute Stroke Care. 
  Munster, IN, Mar 5, 2014; Anslip, IL - 5/28/2014
• “Novel Treatments for Hemorrhagic Stroke” and “Deconstructing a Neurosurgical Disease: Cavernous Angioma as a Paradigm”. 
  University of Calgary, Calgary and Banff, Alberta, Canada - 3/13/2014
• “Progress Update on Clinical trials: MISTIE III”. 
  San Diego, CA - 2/11/2014
• “The CCM3 Phenotype in Endothelial Cells and Mouse”, “Rock Activation as Therapy for CCM”, “Permeability, Lesion Counts and QSM as Putative Biomarkers of CCM Disease i... 
  Universite de Paris, Faculte De Medecine Denis Diderot, Paris, France - 1/6/2014
• “Dural Arteriovenous Malformations”, “Novel Treatments for Intracerebral Hemorrhage”, “Deconstructing a Neurosurgical Disease: Cerebral Cavernous Malformations”, and “... 
  Pinamar, Argentina - 11/27/2013
• The Role of the Surgical Center and Surgical Matters that Matter. 
  Baltimore, MD - 11/8/2013
• “Exceptional Aggressiveness of CCM3/PDCD10 Disease”, and Strategies for Clinical Trials (clinical outcomes versus biomarkers)”. 
  Washington, DC - 11/7/2013
• “Scientific Method in Neurosurgery: History and Philosophy” and “Translational and Integrational Research: The Cavernous Malformations as a Disease Model”. 
  Marine Biology Laboratory, Woods Hole, MA - 10/26/2013
• “Historian Presentation” 
  San Francisco, CA - 10/19/2013
• “Innovations in the Management of Intracerebral Hemorrhage” and “Hematology and Coagulation for Neurosurgeons: Dangers and Solutions”. 
  San Francisco, CA - 10/19/2013
• How to Manage a MISTIE Patient (Trial Prototol and surgical Matters that Matter). 
  Chicago, IL - 10/16/2013
• “The Road to MISTIE III”: Lessons From Phase II Trial of Novel Surgical Therapy and Plans for Definitive Trial. 
  Newport Beach, CA - 9/26/2013
• Surgical Matters that Matter and Lessons Learned from Phase II Trial of Thrombolysis for ICH. 
  Chicago, IL - 9/10/2013
• Invited lectured on “Acute Neurologic Evaluation” and “Emergency Cranial Imaging” and Hands-on Decision-Making Examiner. 
  Chicago, IL - 7/12/2013
• Biology of the Cavernous Angioma. 
  University of Iowa, Iowa City, IA - 5/2/2013
• Mainstream and Boundaries: Reflections on Expertise and the Philosophy of Neurovascular Surgery. 
  The Gordon Center for the Sciences, University of Chicago, Chicago, IL - 4/25/2013
• “Developing new Treatments for Intracerebral and Intraventricular Hemorrhage." 
  Philadelphia, PA - 3/7/2013
• “Intracranial Vascular Malformations”. 
  Honolulu, HI - 2/6/2013
• ”Biomarkers of CCM Disease in Man”, “Constructing Recombinant Antibodies Against the Antigenic Trigger in Human CCM”, and “Results of Long Term Fasudil Therapy in CCM1... 
  Washington, DC - 11/15/2012
• “Clinical Trials Roadmap” and “Genetics and Clinical Aspects”. 
  Washington, DC - 11/15/2012
• “Scientific Method in Neurosurgery: History and Philosophy” and “From Genes to Treating Disease: The Cavernous Malformations as a Disease Model”. 
  Marine Biology Laboratory, Woods Hole, MA - 10/28/2012
• Quantitative iron burden as a biomarker of cumulative hemorrhages in cerebral cavernous malformation: Studies in mouse and man. 
  Chatham, MA - 10/19/2012
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