IraHarryPastanMD

PubMed

• 16 citations
  Diphthamide affects selenoprotein expression: Diphthamide deficiency reduces selenocysteine incorporation, decreases selenite sensitivity and pre-disposes to oxidative...
  Klaus Mayer, Olaf Mundigl, Hubert Kettenberger, Fabian Birzele, Sebastian Stahl
  Redox Biology. 2019-01-01
• 39 citations
  Loss of diphthamide pre-activates NF-κB and death receptor pathways and renders MCF7 cells hypersensitive to tumor necrosis factor.
  Sebastian Stahl, Ana Rita Da Silva Mateus Seidl, Axel Ducret, Sabine Kux van Geijtenbeek, Sven Michel
  Proceedings of the National Academy of Sciences of the United States of America. 2015-08-25
• 36 citations
  Tolerogenic nanoparticles restore the antitumor activity of recombinant immunotoxins by mitigating immunogenicity.
  Ronit Mazor, Emily M. King, Masanori Onda, Nicolas Çuburu, Selamawit Addissie
  Proceedings of the National Academy of Sciences of the United States of America. 2018-01-23

Abstracts/Posters

• Moxetumomab Pasudotox-Tdfk in Heavily Pretreated Patients with Relapsed/Refractory Hairy Cell Leukemia (HCL): Long-Term Follow-up from the Pivotal Phase 3 Trial
  Ira Pastan, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019

Lectures

• Molecular Remissions with Anti-CD22 Recombinant Immunotoxin Moxetumomab Pasudotox Are Associated with Improved Complete Remission Durations during Phase I and III Testing 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Molecular Remissions with Anti-CD22 Recombinant Immunotoxin Moxetumomab Pasudotox Are Associated with Improved Complete Remission Durations during Phase I and III Testing 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Biologic Therapeutics Seminar Series - Systems Approaches to Antibody-based Immunotherapy of Cancer 
  Washington University School of Medicine, Saint Louis, Missouri - 5/16/2012