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Office
3601 21st Ave S
Nashville, TN 37232Phone+1 615-322-3000
Summary
- Since I became a breast cancer clinical researcher, my mission and goal have always been to mitigate breast cancer, which still remains the most common cancer in women in the world. After 20 years in academia and clinical practice, my current role at AstraZeneca allows me to impact breast cancer care in a much larger scale, to promote paradigm-shifting and practice-changing treatments to decrease breast cancer mortality, morbidity, and health disparities in a way that is responsive to patients’ needs and addresses the most important knowledge gaps in the breast cancer medical field. My overarching vision is to pioneer and expand novel translational global research and innovative clinical trial development that accelerate the approval of established and novel drugs in the key areas of excellence at AstraZeneca: tumor resistance/ targeted therapies, DNA damage response, antibody-drug conjugates, and immune-oncology.
Prior to joining AstraZeneca, I was a Professor of Medicine and Ingram Professor of Cancer Research at Vanderbilt University Medical Center (VUMC)/ Vanderbilt-Ingram Cancer Center (VICC) for 18 years, and a breast medical oncologist by training. My translational research endeavors were focused on the identification of targetable pathways in breast cancer and mechanisms of resistance to breast cancer therapies, and have been funded by the NCI, SU2C/ AACR, Susan G. Komen Foundation and the Breast Cancer Research Foundation. I have been PI on more than 90 clinical trials, with more than 20 investigator-initiated trials (IITs). I also have had a successful track record of mentoring fellows and junior faculty throughout my career. Nationally, aside from having been an active member of the ECOG-ACRIN Breast Core Committee and the VICC representative of the National Comprehensive Cancer Network (NCCN) Breast Cancer Panel of Experts, I was highly involved with the Translational Breast Cancer Research Consortium (TBCRC).
Education & Training
- Vanderbilt University School of MedicineM.Sc., Clinical Investigation, 2004 - 2006
- University of Illinois College of Medicine at ChicagoFellowship, Hematology and Medical Oncology, 1998 - 2001
- University of Illinois College of Medicine at ChicagoResidency, Internal Medicine, 1994 - 1998
- Paulista School of MedicineClass of 1993, MD
Certifications & Licensure
- TN State Medical License 2003 - 2026
- AL State Medical License 2020 - 2020
- IL State Medical License 1994 - 1997
Awards, Honors, & Recognition
- Komen Scholar Susan G Komen Foundation
- Five Star Awards in the Excellence in Healthcare Awards 2010-2021
- Regional Top Doctor Castle Connolly, 2010-2021
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Clinical Trials
- Trastuzumab Plus Docetaxel in Treating Women With Recurrent or Metastatic Breast Cancer Start of enrollment: 1998 Sep 01
- Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial) Start of enrollment: 2006 Apr 07
- Bevacizumab in Treating Patients With Metastatic Breast Cancer That Overexpresses HER-2/NEU Start of enrollment: 2007 Nov 01
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Publications & Presentations
PubMed
- 1697 citationsTriple-negative breast cancer: challenges and opportunities of a heterogeneous diseaseGiampaolo Bianchini, Justin M. Balko, Ingrid A. Mayer, Melinda E. Sanders, Luca Gianni
Nature Reviews. Clinical Oncology. 2016-11-01 - 147 citationsSacituzumab govitecan (IMMU-132), an anti-Trop-2-SN-38 antibody-drug conjugate for the treatment of diverse epithelial cancers: Safety and pharmacokineticsAllyson J. Ocean, Alexander Starodub, Aditya Bardia, Linda T. Vahdat, Steven J. Isakoff
Cancer. 2017-10-01 - 1318 citationsAdjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast CancerJoseph A. Sparano, Robert Gray, Della F. Makower, Kathleen I. Pritchard, Kathy S. Albain
The New England Journal of Medicine. 2018-06-03
Journal Articles
- Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast CancerMatthew P Goetz, Thomas J Saphner, Joseph A Sparano, Lynne I Wagner, Peter M Ravdin, Daniel F Hayes, Adam M Brufsky, Della F Makower, Sunil S Badve, Robert J Gray, Wil..., The New England Journal of Medicine
- Statistical comparison of dynamic contrast-enhanced MRI pharmacokinetic models in human breast cancerLi X, Welch EB, Chakravarthy AB, Xu L, Arlinghaus LR, Farley J, Mayer IA, Kelley MC, Meszoely IM, Means-Powell J, Abramson VG, Grau AM, Gore JC, Yankeelov TE, Magn Reson Med, 1/1/2012
- Engagement of the CrkL adaptor in interferon alpha signalling in BCR-ABL expressing cellsGrumbach IM, Mayer IA, Uddin S, Lekmine F, Majchrzak B, Yamauchi H, Fujita S, Druker B, Fish EN, Platanias LC, Br J Haematol, 2/1/2001
Press Mentions
- Ingrid Mayer, MD, on the Disappointing Results of the EA1131 TNBC TrialJanuary 4th, 2022
- VICC’s Mayer Departing to Take New Role with AstraZenecaOctober 28th, 2021
- Vanderbilt Joins Worldwide Fight Against COVID-19May 14th, 2020
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Committees
- Steering Committee Member, Translational Breast Cancer Research Consortium (TBCRC) 2018 - Present
- Member, Expert Panel, American Society of Clinical Oncology (ASCO) 2015 - Present
- Expert Panel Member, National Comprehensive Cancer Network (NCCN) 2005 - Present
Professional Memberships
- Member
- Member
- Member
- European Society of Medical Oncology - ESMOMember
Other Languages
- Portuguese, Romanian, French, Spanish
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