InesPiaKoernerMD

PubMed

• 61 citations
  Soluble epoxide hydrolase: regulation by estrogen and role in the inflammatory response to cerebral ischemia.
  Ines P. Koerner, Wenri Zhang, Jian Cheng, Susan M. Parker, Patricia D. Hurn
  Frontiers in Bioscience. 2008-01-01
• 208 citations
  Microglia in ischemic brain injury.
  Jonathan R. Weinstein, Ines P. Koerner, Thomas Möller
  Future Neurology. 2010-03-01
• 110 citations
  Sex, sex steroids, and brain injury.
  Paco S. Herson, Ines P. Koerner, Patricia D. Hurn
  Seminars in Reproductive Medicine. 2009-05-01

Journal Articles

• Peroxisomal translocation of soluble epoxide hydrolase protects against ischemic stroke injury  
  Nelson JW, Zhang W, Alkayed NJ, Journal of Cerebral Blood Flow and Metabolism, 1/1/2015
• Extracranial hypothermia during cardiac arrest and cardiopulmonary resuscitation is neuroprotective in vivo  
  Hutchens MP, Fujiyoshi T, Herson PS, Therapeutic Hypothermia and Temperature Management, 1/1/2014
• Inhibition of Soluble Epoxide Hydrolase after Cardiac Arrest/Cardiopulmonary Resuscitation Induces a Neuroprotective Phenotype in Activated Microglia and Improves Neur...  
  Wang JM, Fujiyoshi T, Kosaka Y, Raybuck JD, Lattal KM, Ikeda M, Herson PS, Journal of Cerebral Blood Flow and Metabolism, 1/1/2013
• Mechanism of the Sex Difference in Neuronal Ischemic Cell Death  
  Fairbanks SL, Young JM, Nelson JW, Davis C, Alkayed NJ, Neuroscience, 1/1/2012
• Microglia in ischemic brain injury  
  Weinstein JR, Möller T, Future Neurology, 1/1/2010
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  Sheldahl LC, Shapiro RA, Briant DN, Dorsa DM, Neuroscience, 1/1/2008
• Soluble epoxide hydrolase: regulation by estrogen and role in the inflammatory response to cerebral ischemia  
  Zhang W, Cheng J, Parker S, Hurn PD, Alkayed NJ, Frontiers in Bioscience, 1/1/2008
• Gender and the injured brain  
  Vagnerova K, Hurn PD, Anesthesia & Analgesia, 1/1/2008
• Polymorphisms in the human soluble epoxide hydrolase gene EPHX2 linked to neuronal survival after ischemic injury  
  Jacks R, Grant DF, DeBarber AE, Koop D, Alkayed NJ, Journal of Neuroscience, 1/1/2007
• Soluble epoxide hydrolase inhibition is protective against ischemic brain injury through blood flow-independent mechanism  
  Zhang W, Noppens R, Graf M, Morriseau C, Hammock B, Falck J, Alkayed NJ, Journal of Cerebral Blood Flow and Metabolism, 1/1/2007
• Induction of cerebral ischemic tolerance by erythromycin preconditioning re-programs the transcriptional response to ischemia and suppresses inflammation  
  Gatting M, Noppens RR, Kempski O, Brambrink AM, Anesthesiology, 1/1/2007
• Mechanism of progesterone neuroprotection of rat cerebellar Purkinje cells following oxygen-glucose deprivation  
  Ardeshiri A, Kelley MH, Hurn PD, Herson PS, European Journal of Neuroscience, 1/1/2006
• Brain protection by anesthetic agents  
  Koerner IP and Brambrink AM, Current Opinion in Anesthesiology, 1/1/2006
• Antibiotic erythromycin induces tolerance against transient global cerebral ischemia in rats (pharmacological preconditioning)  
  Brambrink AM, Diehl K, Strobel G, Kempski O, Anesthesiology, 1/1/2006
• Role of cocaine- and amphetamine-regulated transcript in estradiol-mediated neuroprotection  
  Xu Y, Zhang W, Klaus J, Young J, Sheldahl LC, Hurn PD, Martinez-Murillo F, Alkayed NJ, Proc Natl Acad Sci, 1/1/2006
• Fiberoptic techniques  
  Koerner IP and Brambrink AM, Best Practice & Research Clinical Anesthesiology, 1/1/2005
• Tolerance-inducing dose of 3-Nitropropionic acid modulates bcl-2 and bax balance in the rat brain: a potential mechanism of chemical preconditioning  
  Brambrink AM, Schneider A, Noga H, Astheimer A, Götz B, Heimann A, Welschof M, Kempski O, J Cereb Blood Flow Metab, 1/1/2000
• Analgosedation (Monitored Anesthesia Care) using propofol and piritramide for controlled cyclophoto­coagulation of the eye  
  Scherhag A, Preußner PR, Anesthesiol Reanim, 1/1/2000
• Analysis of a regulatory element in the 5’- untranslated region of the bcl-2 gene  
  Weber-Nordt R, Pfaff P, Finke J, FEBS Letters, 1/1/1997
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Books/Book Chapters

• Perioperative Drug-Drug Interactions 
  Chapter: Two is not always better than one – warfarin, ciprofloxacin and metronidazole 
  Norvelle H, Koerner IPEditors: Marcucci C, Hutchens M, Sandson N, Kirsch J.Springer, Inc2013
• Perioperative Drug-Drug Interactions 
  Chapter: St. John: not such a saint – St. John’s wort and cyclosporine 
  Norvelle H, Koerner IPEditors: Marcucci C, Hutchens M, Sandson N, Kirsch J.Springer, Inc2013
• Handbook of Clinical Neurology 
  Chapter: Chapter 8 Effects of gender and sex steroids on ischemic injury 
  McCullough LD, Hurn PDEditors: Fisher M.Elsevier PublishingEdition 3rd,2008
• Decision Making in Anesthesiology 
  Chapter: Parkinson’s disease 
  Brambrink AM, Koerner IPEditors: Bready L, Noorily S, Dillmann D.Lippincott Williams & WilkinsEdition 4th,2007
• Acute Stroke: Bench to Bedside 
  Chapter: Ischemic preconditioning 
  Koerner IP and Alkayed NJEditors: Bhardwaj A.Marcel Dekker New York2006
• Acute Ischemic Injury and Repair in the Nervous System, Handbook of Neurochemistry and Molecular Neurobiology 
  Chapter: Gender, Sex Steroids, and Cerebral Ischemic Pathobiology 
  Murphy SJ, Hurn PDEditors: Chan P.Kluwer Academic/Plenum PublishingEdition 3rd,2005
• Yearbook of Intensive Care and Emergency Medicine 2004 
  Chapter: Altered genomic response to ischemia: A means of ischemic tolerance induction in the brain? 
  Koerner IP and Brambrink AMEditors: Vincent J-L.Springer-Verlag Berlin Heidelberg2004
• Yearbook of Intensive Care and Emergency Medicine 2003 
  Chapter: Induction of ischemic tolerance in the brain: a novel neuroprotective strategy? 
  Koerner IP and Brambrink AMEditors: Vincent J-L.Springer-Verlag Berlin Heidelberg2003
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Abstracts/Posters

• Deletion of CD36 induces M2 response to injury and supports ischemic tolerance
  Shimizu T, Chen Y, Mader S, 45th Annual Meeting of the American Society of Neurochemistry 2014, Long Beach, CA, 1/1/2014
• Peroxiredoxin-1 and Toll-like receptor 2 pathway contributes to neurotoxic microglial activation after cardiac arrest
  Ikeda M, Fujiyoshi T, Mader S, “Best Abstracts: Basic Science” Session at the ASA Annual Meeting 2014; SNACC Annual Meeting 2014, New Orleans, LA, 2014; New Orleans, LA, 2014, 1/1/2014
• Microglia are activated and contribute to delayed neuronal death after cardiac arrest/cardiopulmonary resuscitation
  Fujiyoshi T, Mader S, SNACC Annual Meeting 2013, San Francisco, CA, 1/1/2013
• Microglia Transplantation Reduces Stroke Injury
  Shimizu T, Mader S, International Stroke Conference 2013, Honolulu, HI, 1/1/2013
• Activated Microglia Contribute to Delayed Neuronal Death After Cardiac Arrest
  Fujiyoshi T, Mader S, 24th Biennial Meeting of the International Society for Neurochemistry and the American Society for Neurochemistry 2013, Cancun, Mexico, 1/1/2013
• Switching Microglia to a Neuroprotective Phenotype Improves Neuronal Survival After Cardiac Arrest
  Fujiyoshi T, Wang J, Raybuck J, Lattal K, SNACC Annual Meeting 2012, Washington, DC, 1/1/2012
• Inhibition of Soluble Epoxide Hydrolase Improves Neuronal Survival after Cardiac Arrest and Alters Microglial Activation towards a Neuroprotective Phenotype
  Wang JM, Fujiyoshi T, Kosaka Y, Herson PS, International Stroke Conference 2012, New Orleans, LA, 1/1/2012
• Inhibition of Soluble Epoxide Hydrolase After Cardiac Arrest/Cardiopulmonary Resuscitation Induces a Neuroprotective Phenotype in Activated Microglia and Reduces Neuro...
  Wang JM, Fujoyoshi T, Kosaka Y, Herson PS, Neurocritical Care Society 9th Annual Meeting 2011, Montreal, Canada, 1/1/2011
• Lasarzik I, Wang J, Kosaka Y, Herson PS, SNACC Annual Meeting 2010, San Diego, CA, 1/1/2010
• Wang J, Koerner IP, International Stroke Conference 2010, San Antonio, TX, 1/1/2010
• Differential Expression of Soluble Epoxide Hydrolase Contributes to Sex Differences in Neuronal Death
  Fairbanks S, Alkayed NJ, SNACC Annual Meeting 2009, 1/1/2009
• Lasarzik I, Wang J, SNACC Annual Meeting 2009, New Orleans, LA, 1/1/2009
• Effects of Inhibition of Soluble Epoxide Hydrolase on Microglia Activation
  Nakayama K, Young J, Campbell C, Wang J, SNACC Annual Meeting 2008, 1/1/2008
• Gene Deletion, but not Pharmacological Inhibition of Soluble Epoxide Hydrolase Suppresses Brain Inflammation after Stroke
  Zhang W, Cheng J, Alkayed NJ, SNACC Annual Meeting 2007, San Francisco, CA, 1/1/2007
• Effects of Genetic Polymorphisms in Human Soluble Epoxide Hydrolase on Neuronal Susceptibility to Ischemic Injury
  Jacks R, Grant DF, Alkayed NJ, International Stroke Conference 2006, Orlando, FL, 1/1/2006
• Polymorphisms in the Human Soluble Epoxide Hydrolase Gene (EPHX2) Linked to Neuronal Survival After Ischemic Injury
  Jacks R, Grant D, Koop D, Alkayed NJ, Annual Meeting of the Society of Neurosurgical Anesthesia and Critical Care 2006, Chicago, IL, 1/1/2006
• Neuroprotective Effect of 14,15-Epoxyeicosatrienoic Acid
  Zhang W, Hurn PD, Alkayed NJ, Society for Neuroscience Annual Meeting 2005, Washington, DC, 1/1/2005
• Soluble Epoxide Hydrolase Gene Deletion Reduces Inflammation after Stroke
  Zhang W, Hurn PD, Koop D, Alkayed NJ, Brain05, Meeting of the Society for Cerebral Blood Flow and Metabolism, Amsterdam, Holland, 1/1/2005
• 14, 15-Epoxyeicosatrienoic Acid Decreases Neuronal Cell Death and Brain Damage After Ischemia
  Zhang W, Hurn PD, Alkayed NJ, SNACC Annual Meeting 2005, Atlanta, GA, 1/1/2005
• Estradiol Replacement Alters Expression of Inflammatory Cytokines after Stroke
  Hurn PD, Parker SM, Alkayed NJ, 32nd Annual Meeting of the Society of Neurosurgical Anesthesia and Critical Care (SNACC), Las Vegas, NV, 1/1/2004
• Effect of Estradiol on Inflammatory Cytokine Expression after Stroke
  Hurn PD, Parker SM, Alkayed NJ, ASA Annual Meeting 2004, Las Vegas, NV, 1/1/2004
• Pharmacological Preconditioning using Erythromycin Reduces Cerebral mRNA Expression of Superoxyd-Dismutases after Transient Global Ischemia
  Noppens, R, Kempski, O, Brambrink, AM, SNACC Annual Meeting 2003, San Francisco, CA, 1/1/2003
• Effects of a single bolus of hypertonic / hyperoncotic solution (HHS) on cortical microcirculation after global cerebral ischemia in rats
  Noppens, R, Christ, M, Kempski, O, Brambrink, AM, SNACC Annual Meeting 2003, San Francisco, CA, 1/1/2003
• Increase of tumor necrosis factor alpha and interleukin 6 mRNA in rat brain after transient global cerebral ischemia is reduced by pharmacological preconditioning
  Gatting, M, Noppens, R, Kempski, O, Brambrink, AM, ASA Annual Meeting 2003, San Francisco, CA, 1/1/2003
• Pharmacological preconditioning using erythromycin differentally regulates cerebral expression of several members of important gene classes after global cerebral ische...
  Gatting, M, Noppens, R, Kempski, O, Brambrink, AM, Brain03, Meeting of the Society for Cerebral Blood Flow and Metabolism 2003, Calgary, Canada, 1/1/2003
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Lectures

• Microglia are activated to a neurotoxic phenotype and exacerbate delayed neuronal death after cardiac arrest 
  Cairns, Australia - 1/26/2015
• Peroxiredoxin-1: A Novel Danger Signal after Cardiac Arrest 
  Oregon Health & Science University, Portland, OR - 1/1/2015
• Peroxiredoxin-1 is a Novel Danger Signal after Cardiac Arrest 
  Oregon Health & Science University, Portland, OR - 1/1/2015
• Postoperative Challenges in Neurocritical Care 
  Seattle, WA - 1/12/2014
• Emergency Neurological Life Support (ENLS) Workshop 
  Orleans, LA - 1/9/2014
• Neuron-microglia communications in cerebral injury after cardiac arrest 
  Stanford University, Palo Alto, CA - 1/1/2014
• Systemic Complications after Acute Brain Injury: Sympathetics on Overdrive? 
  Oregon Health & Science University, Portland, OR - 1/1/2014
• Hemodynamic Management after Subarachnoid Hemorrhage 
  Oregon Health & Science University, Portland, OR - 1/1/2014
• Microglia-Neuronal Communication after Cardiac Arrest – Good Intentions Gone Wrong 
  Oregon Health & Science University, Portland, OR - 1/1/2014
• CD36 Deletion Allows M2 Response to Brain Injury and Supports Ischemic Tolerance 
  Oregon Health & Science University, Portland, OR - 1/1/2014
• Cardiomyopathy & Neurogenic Pulmonary Edema: Sympathetics on Overdrive? 
  Philadelphia, PA - 1/3/2013
• Weathering the Storm: Brain Injury and the Autonomic Nervous System 
  Philadelphia, PA - 1/3/2013
• Doctor, Your PACU Patient just Blew a Pupil – Managing Perioperative Neurologic Emergencies 
  San Francisco, CA - 1/1/2013
• Microglia-Neuronal Crosstalk after Cardiac Arrest – Up to No Good 
  Oregon Health & Science University, Portland, OR - 1/1/2013
• Brain Code – Resuscitation of a Patient with Acutely Blown Pupils in the PACU 
  Washington, DC - 1/12/2012
• Epoxyeicosatrienoic acids (EETs) modulate neuroinflammation and protect the brain after ischemia 
  Baltimore, MD - 1/1/2012
• Critical Care After Subarachnoid Hemorrhage 
  Oregon Health & Science University, Portland, OR - 1/1/2012
• Epoxyeicosatrienoic Acids Modulate Microglial Activation and Protect the Brain After Ischemia 
  Oregon Health & Science University, Portland, OR - 1/1/2012
• Microglia after brain ischemia – friend of foe? 
  Medical College of Wisconsin, Milwaukee, WI - 1/1/2012
• Early Decompressive Hemicraniectomy in Malignant Ischemic Stroke 
  Portland, OR - 1/1/2011
• Systemic Complications of Subarachnoid Hemorrhage 
  Oregon Health & Science University, Portland, OR - 1/1/2011
• European Health Care Systems 
  Oregon Health & Science University, Portland, OR - 1/1/2011
• Hemodynamic Monitoring in the Neurosciences Intensive Care Unit 
  Portland, OR - 1/1/2010
• Towards Individualized Treatment: The Role of Soluble Epoxide Hydrolase in Ischemic Neuronal Injury 
  Massachusetts General Hospital, Boston, MA - 1/1/2008
• Arachidonic Acid Metabolism in Cerebral Ischemia and Neuroprotection 
  Oregon Health & Science University, Portland, OR - 1/1/2007
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