IftikharJKulloMD

Journal Articles

• Return of Genomic Results in the Genomic Medicine Projects of the EMERGE Network  
  Kullo IJ, Haddad R, Prows, CA, Holm I, Sanderson SC, Garrison NA, Sharp RR, Smith ME, Kuivaniemi H, Bottinger EP, Connolly J, Keating BJ, McCarty CA, Williams MS, Jarv..., Front Genet, 1/26/2014
• The ATXN2-SH2B3 Locus Is Associated with Peripheral Arterial Disease: An Electronic Medical Record-based Genome-wide Association  
  Kullo IJ, Pathak J, Savova GK, Ali Z, Chute CG, Front Genet, 1/25/2014
• Family History as a Risk Factor for Peripheral Arterial Disease  
  Khaleghi M, Isseh IN, Bailey KR, Kullo IJ, Am J Cardiol, 1/15/2014
• Whole Exome Sequencing Implicates an INO80D Mutation in a Syndrome of Aortic Hypoplasia, Premature Atherosclerosis, and Arterial Stiffness  
  Shameer K, Klee EW, Dalenberg AK, Kullo IJ, Circ Cardiovasc Genet, 1/13/2014
• Return of Genomic Results to Research Participants: The Floor, the Ceiling, and the Choices In Between  
  Jarvik GP, Amendola LM, Berg JS, Brothers K, Clayton EW, Chung W, Evans BJ, Evans JP, Fullerton SM, Gallego CJ, Garrison NA, Gray SW, Holm IA, Kullo IJ, Lehmann LS, Mc..., Am J Hum Genet, 1/5/2014
• Inactivating Mutations in NPC1L1 and Protection from Coronary Heart Disease  
  The Myocardial Infarction Genetics Consortium Investigators, N. Engl. J. Med, 1/1/2014
• The Association of 9p21 -3 Locus with Coronary Atherosclerosis: A Systematic Review and Metaanalysis  
  Munir MS, Wang Z, Alahdab F, Steffen MW, Erwin PJ, Kullo IJ, Murad MH, BMC Med Genet, 1/1/2014
• A Summary and Critical Assessment of the 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Disease Risk in Adults: ...  
  Lopez-Jimenez F, Simha V, Thomas RJ, Allison TG, Basu A, Fernandes R, Hurst RT, Kopecky SL, Kullo IJ, Mulvagh SL, Thompson WG, Trejo-Gutierrez JF, Wright RS, Mayo Clin Proc, 1/1/2014
• A Perspective on the New American College of Cardiology/American Heart Association Guidelines for Cardiovascular Risk Assessment  
  Kullo IJ, Trejo-Gutierrez JF, Lopez-Jimenez F, Thomas RJ, Allison TG, Mulvagh SL, Arruda-Olson AM, Hayes SN, Pollak AW, Kopecky SL, Hurst RT, Mayo Clin Proc, 1/1/2014
• Family History as a Risk Factor for Carotid Artery Stenosis  
  Khaleghi M, Isseh IN, Jouni H, Sohn S, Bailey KR, Kullo IJ, Stroke, 1/1/2014
• Predicting Long-term Cardiovascular Risk Using the Mayo Clinic Cardiovascular Risk Score in a Referral Population  
  Dhoble A, Lahr BD, Allison TG, Bailey KR, Thomas RJ, Lopez-Jimenez F, Kullo IJ, Gupta B, Kopecky SL, Am J Cardiol, 1/1/2014
• Preemptive Genotyping for Personalized Medicine: Design of the Right Drug, Right Dose, Right Time - Using Genomic Data to Individualize Treatment Protocol  
  Bielinski SJ, Olson JE, Jyotishman P, Weinshilboum RM, Wang L, Lyke KJ, Ryu E, Targonski PV, Van Norstrand MD, Hathcock MA, Takahashi PY, McCormick JB, Johnson KJ, Mas..., Mayo Clin Proc, 1/1/2014
• A Genome- and Phenome-wide Association Study to Identify Genetic Variants Influencing Platelet Count and Volume and Their Pleiotropic Effects  
  Shameer K, Denny JC, Ding K, Jouni H, Crosslin DR de Andrade M, Chute CG, Peissig P, Pacheco JA, Li R, Bastarche L, Kho AN, Ritchie MD, Masys DR, Chisholm RL, Larson E..., Hum Genet, 1/1/2014
• Genetic Variants That Confer Resistance to Malaria Are Associated with Red Blood Cell Traits in African Americans: An Electronic Medical Record-based Genome Wide Assoc...  
  Ding K, de Andrade M, Manolio T, Crawford DC, Rasmussen-Torvik LJ, Ritchie MD, Denny JC, Masys DR, Jouni H, Pachecho JA, Kho AN, Roden DM, Chisholm R, Kullo IJ, G3, 1/1/2013
• Hypertension in Pregnancy Is Associated with Elevated C-reactive Protein Levels Later in Life  
  Brown CM, Turner ST, Bailey KR, Mosley TH Jr, Kardia SL, Wiste HJ, Kullo IJ, Garovic VD, J Hypertens, 1/1/2013
• The Electronic Medical Records and Genomics (EMERGE) Network: Past, Present and Future  
  Gottesman O, Kuivaniemi H, Tromp G, Faucett WA, Li R, Manolio TA, Sanderson SC, Kannry J, Zinberg R, Basford MA, Brilliant M, Carey DJ, Chisholm RL, Chute CG, Connolly..., Gen Med, 1/1/2013
• Ethical, Legal and Social Implications of Incorporating Genomic Information into Electronic Health Records  
  Hazin R, Brothers K, Malin BA, Koenig BA, Sanderson S, Rothstein M, Williams MS, Clayton EW, Kullo IJ, Genet Med, 1/1/2013
• Hypertension in Pregnancy Is Associated with Elevated Homocysteine Levels Later in Life  
  White WM, Turner ST, Bailey KR, Mosley TH Jr, Kardia SL, Wiste HJ, Kullo IJ, Garovic VD, Am J Obstet Gynecol, 1/1/2013
• An Information Extraction Framework for Cohort Identification Using Electronic Health Records  
  Liu H, Bielinski SJ, Sohn S, Murphy S, Wagholikar KB, Jonnalagadda SR, Ravikumar KE, Wu ST, Kullo IJ, Chute CG, AMIA Summits Transl Sci Proc, 1/1/2013
• Validation of Electronic Medical Record-based Phenotyping Algorithms: Results and Lessons Learned from the EMERGE Network  
  Newton KM, Peissig PL, Kho AN, Bielinski SJ, Berg RL, Choudhary V, Basford M, Chute CG, Kullo IJ, Li R, Pacheco JA, Rasmussen LV, Spangler L, Denny JC, J Am Med Inform Assoc, 1/1/2013
• A Sequence Variant Associated with Sortilin-1 (SORT1) On 1p133 Is Independently Associated with Abdominal Aortic Aneurysm  
  Jones GT, Bown MJ, Gretarsdottir S, Romaine SPR, Helgadottir A, Yu G, Tromp G, Norman PE, Jin C, Baas AF, Blankensteijn JD, Kullo IJ, …… Kuivaniemi H, Samani NJ, Stefa..., Hum Mol Genet, 1/1/2013
• Genome- and Phenome-wide Analysis of Cardiacconduction Identifies Markers of Arrhythmia Risk  
  Ritchie MD, Denny JC, Zuvich RL, Crawford DC, Schildcrout JS, Bastarache L, Ramirez AH, Mosely JD, Pulley JM, Basford MA, Bradford Y, Rasmussen LV, Pathak J, Chute CG,..., Circulation, 1/1/2013
• Ethnic Differences in Ankle Brachial Index Are Present in Middleaged Individuals without Peripheral Arterial Disease  
  Singh S, Bailey KR, Kullo IJ, Int J Cardiol, 1/1/2013
• Associations of Candidate Biomarkers of Vascular Disease with the Ankle-brachial Index and Peripheral Arterial Disease  
  Ye Z, Ali Z, Klee GG, Mosley Jr TH, Kullo IJ, Am J Hypertens, 1/1/2013
• Enhancing the Power of Genetic Association Studies through the Use of Silver Standard Cases Derived from Electronic Medical Records  
  McDavid A, Crane PK, Newton KM, Crosslin DR, McCormick W, …, Kullo I, Li R, Mirel D, Crenshaw A, Bowen JD, Li G, Tsuang D, McCurry S, Teri L, Larson EB, Jarvik GP, Car..., PLoS ONE, 1/1/2013
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Books/Book Chapters

• Strandness's Duplex Scanning in Vascular Disorders 
  Chapter: Cardiovascular Risk Assessment in the Vascular Laboratory 
  Coutinho T, Kullo IJ2014
• Mayo Clinic Cardiology: Concise Textbook 
  Chapter: Novel Biomarkers for Coronary Artery Disease Risk 
  Page 571 - 573Kullo IJEditors: Murphy JG; et al.Mayo Clinic Scientific PressEdition 4th,2013
• Curr Protoc Hum Genet 
  Chapter: Quality Control Procedures for Genome-wide Association Studies 
  Page 1 - 18Turner S, Armstrong LL, Bradford Y, Carlson CS, Crawford DC, Crenshaw AT, de Andrade M, Doheny KF, Haines JL, Hayes G, Jarvik G, Jiang L, Kullo IJ, et al.Wiley Online Library2011
• Asymptomatic Atherosclerosis: Pathophysiology, Detection and Treatment 
  Chapter: Ultrasound Assessment of Brachial Artery Reactivity 
  Page 395 - 410Malik AR, Kullo IJEditors: Naghavi M.Humana Press. (Contemporary Cardiology.), New York2010
• Advances in Clinical Chemistry 
  Chapter: Atherogenic Lipoprotein Subprofiling 
  Page 295 - 317Ellington A, Kullo IJEditors: Makowski G.Elsevier, Oxford, UK2008
• The Year in Hypertension 
  Chapter: Systolic and Pulse Pressure in Hypertension: What Have We Learnt? 
  Page 211 - 226Safar ME, Amar J, Blacher J, Bots M, Willum-Hansen T, Kullo I, et al.Editors: Townsend R.Clinical Publishing, Oxford2008
• Encyclopedia of Life Sciences (ELS) 
  Chapter: Molecular Genetics of Susceptibility to Coronary Heart Disease 
  Kullo IJ, Ding KJohn Wiley & Sons, Ltd, Chichester2008
• The Echo Manual 
  Chapter: Vascular Imaging and Tonometry 
  Page 383 - 389Malik AR, Kullo IJEditors: Oh JK, Seward JB, Tajik AJ.Lippincott Williams & Wilkins, Philadelphia, PAEdition 3rd,2007
• Mayo Clinic Cardiology: Concise Textbook 
  Chapter: Novel Risk Markers for Atherosclerosis 
  Page 725 - 733Kullo IJEditors: Murphy JG, Lloyd MA.Mayo Clinic Scientific Press: Informa Healthcare, RochesterEdition 3rd,2007
• Interventional Cardiology 
  Chapter: Nontraditional Risk Factors for Atherosclerosis 
  Page 723 - 731Kullo IJEditors: King SB III, Yeung AC.McGraw-Hill Medical, New York2007
• Mayo Clinic Cardiology Review 
  Chapter: Novel Risk Markers for Atherosclerosis 
  Kullo IJEditors: Murphy JG.2006
• Mayo Clinic Cardiology Review 
  Chapter: Pathogenesis of Atherosclerosis 
  Schwartz RS, Kullo IJ, Edwards WDEditors: Murphy JG.Futura2001
• Heart Physiology and Pathophysiology 
  Chapter: Gene Transfer in Cardiovascular Therapy 
  Page 1233 - 1243Kullo IJ, Simari RSEditors: Sperelakis N.Academic Press2000
• Current Reviews in Interventional Cardiology 
  Chapter: Clinical and Experimental Studies with Newer Antithrombins 
  Page 201 - 214Kullo IJ, Holmes DR Jr., Schwartz RSEditors: Holmes DR, Serruys, P.Current Medicine1997
• Endocrinology: Endocrinology of the Cardiovascular System 
  Chapter: C-type Natriuretic Peptide: The Vascular Component of the Natriuretic Peptide System 
  Kullo IJ, Burnett JC JrEditors: Sowers J.1996
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Abstracts/Posters

• Inflammation in African Americans with Heightened Vascular Risk and Cognitive Decline
  Simpson BN, Griswold ME, Litrette S, Bridges JM, Bielak LF, Peyser PA, Turner ST, Kullo I, Mosley TH, Windham B, J Am Geriatr Soc, 1/1/2014
• Inflammation and Physical Function in African Americans and European Americans with Cardiovascular Risk Factors
  Wilkening SR, Lirette S, Kullo IJ, Turner ST, Griswold ME, Mosley TH, Windham B, J Am Geriatr Soc, 1/1/2014
• Family History of Peripheral Arterial Disease: Number of Affected Relatives and Younger Age Are Associated with Greater Odds of Peripheral Arterial Disease
  Isseh IN, Khaleghi M, Bailey KR, Kullo IJ, American Heart Association Scientific Sessions, Dallas, TX, 1/17/2013
• Ventricular-arterial Coupling Is Altered in Patients with Peripheral Arterial Disease and Associated with Mortality
  Ye Z, Smith CY, Pellikka PA, Borlaugh BA, Kullo IJ, American Heart Association Scientific Sessions, Dallas, TX, 1/17/2013
• Arterial Stiffness Is Associated with Increase in Blood Pressure and Hypertension Severity over Time in Treated Hypertensives
  Coutinho T, Kullo I, J Am Coll Cardiol, 1/1/2013
• Family History as a Risk Factor for Peripheral Arterial Disease
  Khaleghi M, Bailey K, Kullo I, J Am Coll Cardiol, 1/1/2013
• An Information Extraction Framework for Cohort Identification Using Electronic Health Records.
  Liu H, Bielinski S, Sohn S, Murphy S, Wagholikar K, Jonnalagadda S, Ravikumar KE, Kullo IJ, Chute C, AMIA Summits Transl Sci Proc, 1/1/2013
• Identifying Abdominal Aortic Aneurysm Cases and Controls Using National Language Processing of Radiology Reports
  Sohn S, Ye Z, Liu H, Chute CG, Kullo IJ, AMIA Summits Transl Sci Proc, 1/1/2013
• The Qatar Cardiovascular Biorepository (QCBio): Design and Progress to Date
  Kullo IJ, Qatar Foundation Annual Research Forum Proceedings, 1/1/2013
• Novel Coronary Heart Disease Markers Many Years after Hypertensive Pregnancy
  Asad R, Weissgerber TL, Turner S, Bailey K, Mosely T, Kardia S, Wiste H, Kullo I, Garovic V, Eur Heart J, 1/1/2013
• Sex Differences in the Associations of Arterial Hemodynamic Load with Left Ventricular Hypertrophy and Remodeling
  Coutinho T, Pellikka PA, Kullo IJ, Eur Heart J, 1/1/2013
• Family History of Peripheral Arterial Disease: Number of Affected Relatives and Younger Age Are Associated with Greater Odds of Peripheral Arterial Disease
  Isseh IN, Khaleghi M, Bailey KR, Kullo I, Circulation, 1/1/2013
• Ventricular-arterial Coupling in Altered in Patients with Peripheral Arterial Disease and Associated with Mortality
  Ye Z, Smith C, Pellikka PA, Borlaug BA, Kullo I, Circulation, 1/1/2013
• Admixture Analysis of Lipoprotein (A)
  de Andrade M, Matsumoto MM, Lesnick T, Kardia S, Kullo IJ, Ann Hum Genet, 1/1/2012
• Merging Genomic Data for Research in the Electronic Medical Records and Genomics Network: Lessons Learned in EMERGE
  Ritchie MD, Setia SZ, Armstrong GD, Armstrong L, Bradford Y, Crawford DC, Crosslin DR, de Andrade M, Doheny KF, Hayes MG, Jarvik GP, Kullo I, Li RL, McCarty CA, Mirel ..., Genet Epidemiol, 1/1/2012
• Sex Differences in Arterial Stiffness and Arterial-ventricular Interactions
  Coutinho T, Pellikka PA, Kullo IJ, J Am Coll Cardiol, 1/1/2012
• Proximal Aortic Stiffness and Pulsatile Hemodynamic Load Are Associated with Impaired Left Ventricular Longitudinal Deformation in Patients with Preserved Ejection Fra...
  Coutinho T, Ye Z, Pellikka PA, Borlaug BA, Khan MB, Villarraga HR, Kullo IJ, Circulation, 1/1/2012
• Genetic Loci Implicated in Erythroid Differentiation and Cell Cycle Regulation Are Associated with Red Blood Cell Traits
  Ding K, Shameer K, Jouni H, Masys DR, Jarvik GP, Kho AN, Ritchie MD, McCarty CA and Kullo IJ, Am Soc Hum Genet 61 st Annual Meeting, Montreal, Canada, 1/11/2011
• Mutation Spectrum of Aortic Hypoplasia-vascular Calcification Syndrome by Whole Exome Sequencing
  Kullo IJ, Ding K, Shameer K, Am Soc Hum Genet 61 st Annual Meeting, Montreal, Canada, 1/11/2011
• The Association of Leptin with Left Ventricular Mass in African American Adults with Hypertension
  Al-Omari MA, Mosley TH, Kullo IJ, J Am Coll Cardiol, 1/1/2011
• Associations of 47 Candidate Biomarkers in Etiologic Pathways of Arteriosclerosis with Pulse Pressure in African Americans and Non-Hispanic Whites
  Coutinho TA, Turner S, Mosley TH, Kullo IJ, J Am Coll Cardiol, 1/1/2011
• Association of a Polymorphism in Slco1b1 with Statininduced Myalgias, Myositis and Myopathy: An Electronic Medical Record Based Pharmacogenetic Study
  Khan AA, Ding K, Khader S, Kullo IJ, J Am Coll Cardiol, 1/1/2011
• Admixture Analyses of Lipoprotein (A) Levels.
  De Andrade M, Matsumoto M, Lesnick T, Boerwinkle E, Kardia S, Kullo I, Circulation, 1/1/2011
• Complement Receptor 1 Gene Variants Are Associated with Erythrocyte Sedimentation Rate
  Kullo I, Ding K, Khader S, McCarty CA, Jarvik G, Denny JC, Ritchie MD, Ye Z, Crosslin DR, Chisholm RL, Manolio TA, Chute CG, Am J Hum Gen, 1/1/2011
• Genetic Interactions with Serum Homocysteine Levels Predicts Coronary Artery Calcification in GENOA, with Replication in the Framingham Heart Study
  Kim DS, Wu CY, Smith J, Bielak LF, Peyser PA, Sun YV, Sheedy II PF, Kullo IJ, Turner ST, Kardia S, Circulation, 1/1/2011
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Lectures

• EHR-based Genomic Discovery and Implementation 
  Cedars Sinai Medical Center, Los Angeles CA - 1/1/2015
• Can We Use Genomic Data to Individualize CHD Risk? 
  Sedona AZ - 1/31/2014
• New Guidelines for Assessing Cardiovascular Risk 
  1/25/2014
• Arterial Stiffness in Peripheral Arterial Disease 
  1/17/2014
• Coronary Heart Disease: Can Genetics Identify the High Risk Patient? 
  Hyatt Regency McCormick Place, Chicago, IL - 1/16/2014
• Genetic Testing for CVD Risk Assessment and Prevention: Fact or Fiction? 
  Trendy Topics in Preventive Cardiology - 1/15/2014
• Peripheral Arterial Disease: Natural History, Epidemiology and Medical Therapy 
  Rochester, MN - 1/12/2014
• Diseases of the Peripheral Arteries and Vasculitides 
  Rochester, MN - 1/8/2014
• Novel Risk Factors and Arterial Health 
  Miami FL - 1/7/2014
• Genetic Screening, Fact or Fiction 
  Miami FL - 1/7/2014
• Genetic Testing for Coronary Heart Disease Risk 
  Rochester Minnesota - 1/6/2014
• Fibromuscular Dysplasia 
  Cleveland OH - 1/1/2014
• Diseases of the Aorta and Peripheral Arteries 
  Rochester, MN - 1/25/2013
• Coronary Artery Disease in a Young Patient 
  Washington, DC - 1/25/2013
• Genomics in the Clinic 
  George Washington University Hospital, Washington, DC - 1/25/2013
• Mayo Genomic Medicine Pilot Project Update 
  Bethesda, MD - 1/25/2013
• EMR-based Genomic Studies 
  University of Illinois-Urbana, IL - 1/23/2013
• An Information Extraction Framework for Cohort Identification Using Electronic Health Records 
  San Francisco, CA - 1/21/2013
• Identifying Abdominal Aortic Aneurysm Cases and Controls Using Natural Language Processing of Radiology Reports 
  San Francisco, CA - 1/21/2013
• Beyond Blood Pressure: The Case for Measuring Arterial Function 
  Boca Raton, FL - 1/13/2013
• EMR-based Genomics: Discovery and Implementation 
  Institute of Personalized Medicine, Mount Sinai Medical Center, New York - 1/10/2013
• Myocardial Infarction Genes (MI-GENES) Study 
  Bethesda, MD - 1/7/2013
• Genetic Variants Influencing Cardiorespiratory Fitness: Phenotyping Challenges and Preliminary Results 
  Bethesda, MD - 1/7/2013
• Return of Results Working Group Update 
  Bethesda, MD - 1/7/2013
• eMERGE, eMERGE PGx and the RIGHT Protocol 
  1/4/2013
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Other

• Mayo Task Force Challenges Heart of National Recommendations 
  Post Bulletin
  Rochester MN - 1/31/2014
• De nouvelles responsabilites pour le medecin et la societe 
  Isabelle Trocheris, Le Quotidien du Medecin
  1/30/2013
• How Mayo Clinic is Identifying Cases of One Disease Using Billing Codes, Becker's Hospital Review 
  Helen Gregg
  http://www.beckershospitalreview.com/healthcareinformation-technology/how-mayo-clinic-is-identifying-cases-of-one-disease-using-billingcodes.html
  1/18/2013
• Fibromuscular Dysplasia 
  Robert McBane, MD, Sanjay Misra MD and Thom Rooke MD
  http://Heart.org
  1/5/2013
• Peripheral Artery Disease: Shining Light on a Neglected Condition 
  Kate Ledger, Minnesota Medicine
  1/1/2013
• How the EMERGE Project Grant Affects Patients 
  This Week at Mayo
  1/23/2011
• American Health Association Scientific Sessions: Reclassification of 10-y Coronary Heart Disease Risk Probability by Incorporating Genetic Markers; Insights from the M... 
  
  Chicago, IL - 1/16/2010
• Vascular Age 
  ACCEL Interview. Scientific Sessions ACC
  1/31/2008
• Novel Biomarkers 
  ACCEL Interview. Scientific Sessions AHA
  1/6/2007
• Aortic Pulse Wave Velocity Associated with Presence and Quantity of Coronary Artery Calcium 
  
  http://wwww.heart.org
  1/22/2006
• Simple Test to Indicate Heart Disease 
  Mayo Clinic Health Newsletter
  1/1/2006
• Ten-minute Test Predicts Heart Disease 
  
  1/1/2006
• Should You Track Your Plaque? 
  Better Homes and Gardens: Heart-Healthy Living
  1/1/2006
• Aortic Pulse Wave Velocity Predictive of Coronary Calcium 
  Today in Cardiology
  1/1/2006
• New Noninvasive Test Detects Heart Attack Risk 
  Bottom Line Health Newsletter.
  1/1/2006
• A New Test for Heart Disease Risk 
  KTTC TV
  1/1/2006
• Unmasking Hearts at Risk 
  Health & Science
  1/1/2006
• Early Atherosclerosis Clinic 
  Hometown Health Letter, Mayo Clinical Update, Mayo Clinic Cardiovascular Update, Medical Edge
  1/1/2004
• CRP: A New Adjunct to Predicting Cardiovascular Risk 
  Mayo Clinic Cardiovascular Update
  1/1/2003
• CRP: A New Cardiovascular Risk Factor 
  WCCO TV
  1/1/2003
• Cardiology Today and Tomorrow: New Approaches to Risk Reduction 
  
  Mayo Clinic. Rochester, MN - 1/1/2001
• More Attention Being Paid to High Homocysteine Levels as a Risk Factor in Heart Disease. 
  
  http://www.theheart.org
  1/1/2000
• Cardiology Today and Tomorrow: New Approaches to Atherosclerosis 
  
  Mayo Clinic. Rochester, MN - 1/1/2000
• Cardiology Today and Tomorrow: Managing the Vascular Bed 
  
  Mayo Clinic. Rochester, MN - 1/21/1999
• Newer Risk Factors for Atherosclerosis. Emerging Paradigms in Atherosclerosis, Joint Cardiovascular Diseases and Mayo 
  Medical Laboratory Symposium
  1/7/1999
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