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Office
The Kirklin Clinic of UAB Hospital
2000 6th Avenue South
Birmingham, AL 35233Phone+1 205-934-7170Fax+1 205-934-6507
Summary
- I am a fellowship-trained neuro-oncology surgeon, specialized in the surgical care of brain tumors. I lead the Neuro-Oncology Program in the Comprehensive Cancer Center at UAB as co-Leader. I also contribute to various clinical trials for brain tumors.
Education & Training
Ohio State University HospitalFellowship, Neurosurgical Oncology, 2009 - 2012
Ronald Reagan UCLA Medical CenterPost-Doctoral Fellowship, 2006 - 2009
Faculty of Medicine Kyoto UniversityClass of 1993
Certifications & Licensure
CA State Medical License Current
OH State Medical License 2012 - 2026
AL State Medical License 2015 - 2020
Awards, Honors, & Recognition
- Young Investigator Award American Association of Neurological Surgeons, 2006-2007
Clinical Trials
- AXL Inhibitor BGB324 in Treating Participants With Recurrent Glioblastoma Undergoing Surgery Start of enrollment: 2020 Jan 02
Publications & Presentations
PubMed
- 1 citations5-Aminolevulinic acid increases boronophenylalanine uptake into glioma stem cells and may sensitize malignant glioma to boron neutron capture therapy.Masao Fukumura, Naosuke Nonoguchi, Shinji Kawabata, Ryo Hiramatsu, Gen Futamura
Scientific Reports. 2023-06-22 - 4 citationsAblation efficacy of 5-aminolevulinic acid-mediated photodynamic therapy on human glioma stem cells.Naoki Omura, Naosuke Nonoguchi, Takahiro Fujishiro, Yangtae Park, Naokado Ikeda
Photodiagnosis and Photodynamic Therapy. 2023-03-01 - 33 citationsAlternative RNA splicing modulates ribosomal composition and determines the spatial phenotype of glioblastoma cells.Tatyana D Larionova, Soniya Bastola, Tatiana E Aksinina, Ksenia S Anufrieva, Jia Wang
Nature Cell Biology. 2022-10-01
Journal Articles
- Article Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma via Intercellular Transfer of Splicing FactorsAhmed Mohyeldin, Ichiro Nakano, L James Lee, ScienceDirect
- Combined c-met/Trk Inhibition Overcomes Resistance to CDK4/6 Inhibitors in GlioblastomaIchiro Nakano, Benjamin Purow, Clinical Cancer Research
Authored Content
- On-Chip Clonal Analysis of Glioma-Stem-Cell Motility and Therapy ResistanceJuly 2016
Press Mentions
- Sustained NF-κB-STAT3 Signaling Promotes Resistance to Smac Mimetics in Glioma Stem-like Cells but Creates a Vulnerability to EZH2 InhibitionMarch 4th, 2019
Dying Cancer Cells Make Remaining Glioblastoma Cells More Aggressive and Therapy-ResistantJune 22nd, 2018
Dying Cancer Cells Make Remaining Glioblastoma Cells More Aggressive and Therapy-ResistantJune 21st, 2018- Join now to see all
Grant Support
- National Institute for HealthNational Cancer InstitutePresent
Research History
- ProfessorTherapy development and clinical trials for malignant brain tumors2015 - Present
- Associate ProfessorTherapy development and clinical trials for brain tumors2009 - 2015
Professional Memberships
- Member
- Society for Neuro-oncologyMember
Other Languages
- Japanese
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