Ian Yu Lee MD

PubMed

• Laser Interstitial Thermal Therapy for Intra-Axial Brain Tumors: Everything the Neuroradiologist Should Know.
  Anneliese F Rademacher, Hassan A Fadel, Jacob A Pawloski, Mia Ma, Ken N Nkongchu
  AJNR. American Journal of Neuroradiology. 2025-04-02
• A multi-institutional phase 1 clinical trial exploring upfront multimodal standard of care and combined immunotherapies for newly diagnosed glioblastoma.
  Patrick Y Wen, Andrea Manzanera, Caroline Duault, Edgar Gonzalez-Kozlova, Lenika Lopez
  Neuro-Oncology. 2025-03-22
• The outcomes measured and reported in observational studies of incidental and untreated intracranial meningioma: A systematic review.
  Christopher P Millward, Abdurrahman I Islim, Terri S Armstrong, Heather Barrington, Sabrina Bell
  Neuro-Oncology Advances. 2024-03-19

Journal Articles

• Cerebral edema induced by laser interstitial thermal therapy and radiotherapy in close succession in patients with brain tumor  
  Maraka S, Asmaro K, Walbert T, Lee, I, Lasers in Surgery and Medicine, 1/25/2018
• The Use of Stereotactic Radiosurgery for Benign Spinal Tumors: Single Institution Experience  
  Boyce-Fappiano D, Elibe E, Ryu S, Siddiqui S, Lee I, Rock J, Siddiqui F, J Radiation Oncology, 1/1/2018
• Stereotactic Radiosurgery for Primary and Metastatic Sarcomas of the Spine  
  Elibe E, Boyce-Fappiano D, Ryu S, Siddiqui S, Lee I, Rock J, Siddiqui F, J Applied Radiation Oncology, 1/1/2018
• Re-Irradiation of the Spine with Stereotactic Radiosurgery: Efficacy & Toxicity  
  Boyce-Fappiano D, Elibe E, Zhao B, Siddiqui MS, Lee I, Rock JP, Ryu S, Siddiqui F, Practical Radiation Oncology, 1/24/2017
• Automated Whole Brain Tractography Affects Preoperative Surgical Decision Making  
  Zakaria H, Haider S, Lee I, Cureus, 1/6/2017
• Reproducibility and relative stability in magnetic resonance imaging indices of tumor vascular physiology over a period of 24 hours in a rat 9L gliosarcoma model  
  Nagaraja TN; Elmghirbi R; Brown SL; Shultz LR; Lee I; Keenan KA; Panda S; Cabral G; Mikkelsen T; Ewing JR, Magnetic Resonance Imaging, 1/5/2017
• Reoperation for Recurrent Glioblastoma Multiforme  
  Robin AM, Lee I, Kalkanis SN, Neurosurgery Clinics of North America, 1/1/2017
• Stereotactic radiosurgery for multiple myeloma of the spine  
  Elibe E, Boyce-Fappiano D, Ryu S, Siddiqui MS, Wen N, Lee I, Rock JP, Siddiqui F, J Radiat Oncol, 1/1/2017
• Spine Surgical site infections after the transoral versus posterior approaches to atlantoaxial fusions: A matched cohort study  
  Macki M, Basheer A, Lee I, Kather R, Rubinfeld I, Abdulhak M, J Neurosurg Spine, 1/1/2017
• Advances in surgical approaches in glioblastoma (GBM)  
  Lee I, Chin Clin Oncol, 1/1/2017
• Analysis of the Factors Contributing to Vertebral Compression Fractures After Spine Stereotactic Radiosurgery  
  Boyce-Fappiano D, Elibe E, Schultz L, Ryu S, Siddiqui MS, Chetty I, Lee I, Rock JP, Movsas B, Siddiqui F, Int J Radiation Oncol Biol Phys, 1/1/2017
• A case of symptomatic spinal dural arteriovenous fistula after high-volume lumbar puncture  
  Noh T; Chandra R; Kim J, Lee I, Surg Neurol Int, 1/1/2017
• Surgical Technique for Repair of Complex Skull Base Defects  
  Reinard KA, Basheer A, Jones L, Standring R, Lee IY, Rock JP, Surgical Neurology International, 1/1/2015
• Through the patient�s eyes: the value of a comprehensive brain tumor center  
  Robin AM, Walbert T, Mikkelsen T, Kalkanis SN, Rock J, Lee I, Rosenblum ML, J Neurooncol, 1/16/2014
• Stereotactic radiosurgery for high-grade metastatic epidural cord compression  
  Lee, IY, Omodon M, Rock JP, Shultz L, Ryu S, Journal of Radiosurgery and SBRT, 1/1/2014
• Malignant Gliomas: Current Concepts  
  Lee, I, Kalkanis SN, Rosenblum ML, Neurosurgery Quarterly, 1/1/2010
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Books/Book Chapters

• Spine Radiosurgery. 
  Chapter: Treatment of Spinal Canal Compromise. Chapter 14. 
  Richard Rammo MD, Ian Lee MD, Jack Rock MD and Samuel Ryu MDEditors: Peter Gerszten, MD and Samuel Ryu, MD.Thieme, New York, NYEdition 2nd,2015
• Brain Tumor Imaging. 
  Chapter: Image Guided Surgery. Chapter 15. 
  Victor Chang, MD and Ian Lee, MDEditors: Rajan Jain, MD.Thieme, New York, NY2015
• Controversies in Stereotactic Radiosurgery. 
  Chapter: Spinal Cord Decompression with Spinal Radiosurgery. Chapter 34 
  Samuel Ryu, MD, Ian Lee, MD, and Jack Rock, MDEditors: Jason Sheehan and Peter Gerszten.Thieme, New York, NY2014
• Handbook of Bleeding and Coagulation for Neurosurgeons. 
  Chapter: Intraoperative Non-Hematologic Adjuvant Methods for Preventing Blood Loss. Chapter 17 
  Ian Lee, MD, Raymond Sawaya, MD and Nicholas Levine, MDEditors: Mark G. Hamilton, MD, William T. Couldwell, MD, Graham F. Pineo, MD, and John G. Golfinos, MD.Thieme, New York, NY2014
• Surgical Techniques in Otolaryngology - Head & Neck Surgery: Head & Neck Surgery. 
  Chapter: Anterior Craniofacial Resection. Chapter 4 
  Francis Hall, MD, Ian Lee, MD and Liat Shama, MDJP Brothers2014
• Youmans Neurological Surgery. 
  Chapter: Invasion in Malignant Glioma. 
  Page 1141 - 1150Ian Lee, MD and Mark Rosenblum, MDEditors: Richard Winn.Elsevier, Philadelphia, PA2011
• Spine Radiosurgery. 
  Chapter: Treatment of Spinal Canal Compromise. 
  Page 96 - 103Jack Rock, MD, Samuel Ryu, MD and Ian Lee, MDEditors: Peter Gerszten, MD and Samuel Ryu, MD.Thieme, New York, NY2008
• Neuro-Oncology: The Essentials. 
  Chapter: Pilocytic Astrocytoma and Other Indolent Tumors. 
  Page 266 - 276Jack Rock, MD and Ian Lee, MDEditors: Mark Bernstein, MD and Mitchel S. Berger, MD.Thieme, New York, NY2008
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Abstracts/Posters

• Morphometrics Predicts Overall Survival in Patients with Glioblastoma
  Zakaria H, Rammo R, Massie L, Schultz L, Chang V, Lee I, AANS Annual Meeting, 1/1/2018
• Predicting Survival in Patients with Spinal Metastasis
  Hesham Zakaria MD, Azam Basheer MD, David Boyce-Fappiano, Erinma Ellibe, Ian Lee MD, Farzan Siddiqui MD PhD, Victor Chang MD, CNS Annual Meeting, 1/1/2017
• MR-Guided Laser Interstitial Thermal Therapy in the Treatment of Recurrent Intracranial Meningiomas
  Richard Rammo MD, Hesham Zakaria MD, Lisa Scarpace MS, Ian Lee MD, AANS Annual Meeting Resident Research Symposium, 1/1/2017
• Safety and Efficacy of MR-guided Laser Interstitial Thermal Therapy for Recurrent High Grade Gliomas
  Richard Rammo MD, Azam Basheer MD, David Gold BS, Lisa Scarpace MS, Steven Kalkanis MD, Ian Lee MD, AANS Annual Meeting Resident Research Symposium, 1/1/2017
• Morbidity and Mortality Associated with Laser-Interstitial Thermal Therapy for Unresectable High Grade Gliomas
  Jessin K John MD PhD, Richard Rammo MD, James Snyder DO, Tobias Walbert MD, and Ian Lee MD, AANS Annual Meeting, 1/1/2017
• Stereotactic Radiosurgery for Malignant Intradural and Intramedullary Tumors of the Spine
  Elibe E, Boyce-Fappiano D, Siddiqui S, Lee I, Rock J, Siddiqui F, Int J Radiat Oncol Biol Phys, 1/1/2017
• Repeat Courses of Spine Stereotactic Radiosurgery (SRS): Efficacy & Toxicity
  Elibe E, Boyce-Fappiano D, Siddiqui S, Lee I, Rock J, Siddiqui F, Int J Radiat Oncol Biol Phys, 1/1/2017
• Contouring Guidelines for Post-Operative Spine Stereotactic Radiosurgery
  Boyce-Fappiano D, Elibe E, Siddiqui S, Lee I, Rock J, Siddiqui F, Int J Radiat Oncol Biol Phys, 1/1/2017
• A revisit of the devastating outcome of leptomeningeal disease.
  Ahmad Mattour, Tobias Walbert, Ian Lee, Ding Wang, ASCO Annual Meeting, 1/1/2016
• Combined Stereotactic Radiosurgery and Percutaneous Vertebral Augmentation for Pain Control in Pathological Vertebral Compression Fractures
  Boyce-Fappiano D, Elibe E, Siddiqui S, Lee I, Rock J, Siddiqui F, Int J Radiat Oncol Biol Phys, 1/1/2016
• Single Fraction Stereotactic Radiosurgery for Hepatocellular Carcinoma Spine Metastasis
  Boyce-Fappiano D, Elibe E, Siddiqui S, Lee I, Rock J, Siddiqui F, Int J Radiat Oncol Biol Phys, 1/1/2016
• Single Fraction Stereotactic Radiosurgery for Renal Cell Carcinoma Spine Metastasis
  Boyce-Fappiano D, Elibe E, Siddiqui S, Lee I, Rock J, Siddiqui F, Int J Radiat Oncol Biol Phys, 1/1/2016
• Significance of Hormone Therapy & Bisphosphonate Use on Vertebral Compression Fracture (VCF) Incidence Following Spine Stereotactic Body Radiation Therapy (SBRT) for B...
  Elibe E, Boyce-Fappiano D, Walker E, Siddiqui S, Lee I, Rock J, Siddiqui MSU, Siddiqui F, Int J Radiat Oncol Biol Phys, 1/1/2016
• The Toca 7 study: Phase Ib study of Toca511, a live gamma retrovirus, and Toca FC, an extended release formulation of 5-fluorocytosine combined with standard of care ...
  Michael Vogelbaum, MD PhD, Andrew Lassman MD, Ian Lee MD, Linda Liau MD PhD, Adam Sonabend MD, Tobias Walbert MD PhD, Liqiang Yang, Asha Das MD, Timothy Cloughesy MD, Society for Neuro-Oncology Annual Meeting, 1/1/2016
• Laser interstitial thermal therapy with adjuvant radiotherapy induced cerebral edema in patients with brain tumor
  Stefania Maraka MD, Karam Asmaro MD, Tobias Walbert MD PhD, Ian Yu Lee MD, Society for Neuro-Oncology Annual Meeting, 1/1/2016
• Intra-class correlations of laser-treated high grade gliomas
  Thomas Noh MD, Ian Yu Lee MD, Society for Neuro-Oncology Annual Meeting, 1/1/2016
• Gene Expression Analysis of Pseudoprogression and True Progression in Newly Diagnosed GBM
  Adam Robin MD MS, Laila Poisson PhD, Aditya Raghunathan MD, Lisa Scarpace MS, Charlotte Burmeister MS, Tobias Walbert MD, Denise Leung MD MS, Tim Mikkelsen MD, Ian Lee MD, CNS Annual Meeting - Scientific Session, 1/1/2015
• Spine Surgery for Tumors - Neurosurgeon's Perspective
  Lee I, Practical START Radiosurgery Course, 1/1/2015
• Treating Multiple Brain Tumors: Surgery, Radiosurgery or Both From Tumor Board to Treatment: The HFHS Clinical Experience
  Lee I, International Stereotactic Radiosurgery Society Luncheon Seminar, 1/1/2015
• Laser Ablation for Brain Tumors � Visualase Experience
  Lee I, CNS Annual Meeting Practical Session, 1/1/2015
• Treating Multiple Brain Tumors: Surgery, Radiosurgery or Both. From Tumor Board to Treatment: The HFHS Clinical Experience
  Lee I, CNS Annual Meeting Luncheon Seminar, 1/1/2015
• Somatostatin Receptor mRNA Analysis for Atypical and Anaplastic Meningiomas
  Richard Rammo MD, Laila Poisson PhD, Adam Robin MD MS, Neema Sadry BS, Aditya Raghunathan MD, Ian Lee MD, Jack Rock, MD, CNS Annual Meeting - Scientific Session, 1/1/2015
• Survival Outcomes Associated with Visualase Ablation of Unresectable Tumors
  Jessin John MD PhD, Adam Robin MD MS, Lisa Scarpace MS, Steven Kalkanis MD, Jason Schwalb MD, Ian Lee MD, CNS Annual Meeting - Scientific Session, 1/1/2015
• Intraventricular Glioblastoma: Case Report and Review of Literature
  Aqueel Pabaney MD, Kevin Reinard MD, Ian Lee MD, Jack Rock, MD, CNS Annual Meeting - Scientific Session, 1/1/2015
• A Case Series of 37 Consecutive Laser Ablations for Brain Tumor
  Adam Robin MS MD, Jessin John MD PhD, Steven Kalkanis MD, Jason Schwalb MD, Lisa Scarpace MS, Ian Lee MD, CNS Annual Meeting - Scientific Session, 1/1/2015
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Lectures

• Morphometrics Predicts Overall Survival in Patients with Lung, Breast, Prostate or Myeloma Spine Metastases, Independent of Histology 
  1/1/2018
• Toca 511 & Toca FC: Evaluation of Durable Response Rate in the Post-Resection Setting and Association with Survival in Patients with Recurrent High Grade Glioma. 
  1/1/2018
• New Applications for Laser Ablation in Neuro-Oncology 
  1/1/2018
• Laser Ablation induced BBB Disruption in High Grade Glioma 
  1/1/2018
• Morphometrics Predicts Overall Survival in Patients with Lung, Breast, Prostate, or Myeloma Spine Metastases, Independent of Cancer Histology or Spine Metastatic Burden 
  1/1/2018
• Spine Surgery for Tumors � Neurosurgeon�s Perspective 
  1/1/2018
• Liquid Biopsy for Identification of Newly Diagnosed Glioma 
  1/1/2018
• Genomic Enhancer Methylation is Associated with Biological and Clinical Features of Pituitary Macroadenomas 
  1/1/2018
• Functional genomic elements defined by DNA methylation can distinguish meningioma subgroups 
  1/1/2018
• Genomic functional enhancers defines potential tumorigenesis of G-CIMP-low (IDH-mutant Astrocytoma) tumors independent of promoter methylation 
  1/1/2018
• Using Laser Interstitial Thermal Ablation Induced Blood-Barrier Barrier Disruption to Enhance Drug Delivery in High Grade Glioma 
  1/1/2017
• Intra-class correlations of measured MRI volumes of LITT-treated high grade gliomas 
  1/1/2017
• Laser Interstitial Thermal Therapy for Recurrent Meningioma 
  1/1/2017
• Safety and Efficacy of MR-guided Laser Interstitial Thermal Therapy for Recurrent High Grade Gliomas 
  1/1/2017
• Blood-Brain Barrier and Drug Delivery in Brain Tumors 
  Henry Ford Hospital - 1/1/2017
• LITT for Low Grade Gliomas and in Combination with Other Treatments 
  1/1/2017
• Durable complete responses observed in IDH1 mutated high grade glioma at first recurrence undergoing treatment with Toca 511 and Toca FC. 
  1/1/2017
• A Study of the Safety of Magnetic Resonance Imaging-Guided Laser Interstitial Thermal Therapy Treatment for Cerebral Radiation Necrosis 
  1/1/2017
• Emerging Surgical Technologies for Brain Tumor Surgery 
  Henry Ford Hospital - 1/1/2016
• Psoas Size Predicts Survival in Patients with Lung Cancer Metastasis to the Spine 
  1/1/2016
• Laser Ablation for Brain Tumors 
  1/1/2015
• Volumetric Analysis of 26 Consecutive Laser Ablations 
  1/1/2015
• Laser Interstitial Thermal Ablation for Brain Tumors 
  1/1/2014
• Leptomeningeal Carcinomatosis: A Primer on Pathophysiology and Treatment 
  Henry Ford Hospital - 1/1/2014
• Laser Interstitial Thermal Therapy for Brain Lesions 
  Henry Ford Hospital - 1/1/2014
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