Hyo Sook Han MD

Oncology•Tampa, FL

Breast Cancer

Senior member, Research Director

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12902 Usf Magnolia DrTampa, FL 33612
Book by Phone+1(563) 362-9232

Education & Training

University of Miami/Jackson Health SystemFellowship, Hematology and Medical Oncology, 2005 - 2008
Cleveland Clinic FoundationResidency, Internal Medicine, 2002 - 2005
Seoul National University College of MedicineClass of 1999

Certifications & Licensure

FL State Medical License 2008 - 2026
CA State Medical License 2004 - 2022
OH State Medical License 2002 - 2005
American Board of Internal Medicine Medical Oncology

Clinical Trials

A Study of the Experimental Drug BKM120 With Paclitaxel in Patients With HER2 Negative, Locally Advanced or Metastatic Breast Cancer, With or Without PI3K Activation Start of enrollment: 2012 Aug 01
Completed
Phase 2, Phase 3
A Phase III Study of BKM120 With Fulvestrant in Patients With HR+,HER2-, AI Treated, Locally Advanced or Metastatic Breast Cancer Who Progressed on or After mTORi Start of enrollment: 2012 Oct 03
Terminated
Phase 3
A Phase I Dose Escalation Study of Eribulin Plus Weekly Carboplatin for Metastatic Breast Patients Start of enrollment: 2013 Feb 06
Completed
Phase 1
COGNUTRIN in Breast Cancer Survivors Start of enrollment: 2014 Jul 30
Completed
Early Phase 1
Yoga for Aromatase Inhibitor-associated Joint Pain Start of enrollment: 2013 Sep 01
Completed
Not Applicable
Phase I/IIa Trial of Gemcitabine Plus Trastuzumab and Pertuzumab in Previously Treated Metastatic HER2+ Breast Cancer Start of enrollment: 2014 Sep 05
Completed
Phase 1, Phase 2
Fractionated Stereotactic Radiotherapy (FSRT) in Treatment of Brain Metastases Start of enrollment: 2014 Oct 09
Terminated
Phase 1
Trilaciclib (G1T28), a CDK 4/6 Inhibitor, in Combination With Gemcitabine and Carboplatin in Metastatic Triple Negative Breast Cancer (mTNBC) Start of enrollment: 2017 Feb 02
Terminated
Phase 2
Vaccine to Prevent Recurrence in Patients With HER-2 Positive Breast Cancer Start of enrollment: 2018 Feb 19
ACTIVE_NOT_RECRUITING
PHASE2
Phase 2 Trial of Selinexor (KPT-330) for Metastatic Triple Negative Breast Cancer (TNBC) Start of enrollment: 2015 Jul 08
Completed
Phase 2
Phase I-II Study of Interferon-gamma in Patients With HER-2 Positive Breast Cancer Start of enrollment: 2017 Jun 23
Completed
Phase 1, Phase 2
Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation Start of enrollment: 2021 Sep 08
Recruiting
Phase 1
I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer Start of enrollment: 2010 Mar 01
RECRUITING
PHASE2
Stereotactic Radiation & Abemaciclib in the Management of HR+/HER2- Breast Cancer Brain Metastases Start of enrollment: 2021 Nov 30
RECRUITING
PHASE1, PHASE2
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Publications & Presentations

PubMed

A pilot study incorporating HER2-directed dendritic cells into neoadjuvant therapy of early stage HER2+ER- breast cancer.
Hatem Soliman, Amy Aldrich, Neveen Abdo, Hyo Han, Aixa Soyano
NPJ Breast Cancer. 2025-03-17
Alteration of the Tumor Microenvironment With Intratumoral Dendritic Cells Before Chemotherapy in ERBB2 Breast Cancer: A Nonrandomized Clinical Trial.
Hyo S Han, Amy L Aldrich, Saurabh K Garg, R Jared Weinfurtner, Jonathan V Nguyen
JAMA Oncology. 2025-02-01
Pexidartinib and standard neoadjuvant therapy in the adaptively randomized I-SPY2 trial for early breast cancer.
Hope S Rugo, Mike Campbell, Christina Yau, A Jo Chien, Anne M Wallace
Breast Cancer Research and Treatment. 2025-02-01

Lectures

SGNLVA-002: Single-arm, open label phase Ib/II study of ladiratuzumab vedotin (LV) in combination with pembrolizumab for first-line treatment of patients with unresect...
ASCO Annual Meeting 2019 - Chicago, IL - 6/2/2019

Press Mentions

Intratumoral Dendritic Cell Therapy Shows Promise in Early-Stage ERBB2-Positive Breast CancerDecember 9th, 2024
Vaccinex and Its Collaborators Present Two Abstracts Related to Pepinemab Combination Immunotherapy Trials at 37th Annual Meeting of Society for Immunotherapy of CancerNovember 10th, 2022