Hugo E.VargasMD

PubMed

• Antivirals in Preventing Perinatal Transmission of Hepatitis B: Start and Stop Times are Shifting.
  Norah A Terrault, Hugo E Vargas
  The American Journal of Gastroenterology. 2024-12-10
• Cardiorespiratory Fitness From Cardiopulmonary Exercise Testing Is a Comprehensive Risk-stratifying Tool in Liver Transplant Candidates.
  Dempsey L Hughes, Blanca Lizaola-Mayo, Courtney M Wheatley-Guy, Hugo E Vargas, Pamela M Bloomer
  Transplantation Direct. 2024-12-01
• Fazirsiran for Adults With Alpha-1 Antitrypsin Deficiency Liver Disease: A Phase 2 Placebo Controlled Trial (SEQUOIA).
  Virginia C Clark, Charlie Strange, Pavel Strnad, Antonio J Sanchez, Paul Kwo
  Gastroenterology. 2024-10-01

Journal Articles

• Hepatitis c guidance: aasld-idsa recommendations for testing, managing, and treating adults infected with hepatitis c virus  
  Chung RT, Davis GL, Jensen DM, Masur H, Saag MS, Thomas DL, Aronsohn AI, Charlton MR, Feld JJ, Fontana RJ, Ghany MG, Godofsky EW, Graham CS, Kim AY, Kiser JJ, Kottilil..., Hepatology, 1/1/2015
• Safety profile of boceprevir and telaprevir in chronic hepatitis C: Real world experience from HCV-TARGET  
  Gordon SC, Muir AJ, Lim JK, Pearlman B, Argo CK, Ramani A, Maliakkal B, Alam I, Stewart TG, Vainorius M, Peter J, Nelson DR, Fried MW, Reddy KR, on behalf of the HCV-T..., Journal of Hepatology, 1/1/2015
• Care of the patient with cirrhosis  
  Yadav A, Vargas HE, Clinical Liver Disease, 1/1/2015
• Belatacept-based immunosuppression in de novo liver transplant recipients: 1-year experience from a phase II randomized study  
  Klintmalm GB, Feng S, Lake JR, Wekerle T, Agnes S, Brown KA, Nashan B, Rostaing L, Meadows-Shropshire S, Agarwal M, Harler MB, García-Valdecasas JC, Am J Transplant, 1/1/2014
• The Combination of MK-5172, Peginterferon, and Ribavirin is Effective in Treatment-Naive Patients with Hepatitis C Virus Genotype 1 Infection without Cirrhosis  
  Manns MP, Vierling JM, Bacon BR, Bruno S, Shibolet O, Baruch Y, Marcellin P, Caro L, Howe AYM, Fandozzi C, Gress J, Gilbert CL, Shaw PM, Cooreman MP, Robertson MN, Hwa..., Gastroenterology, 1/1/2014
• Colonoscopy in liver disease  
  Ratuapli SK, Vargas HE, Clin Liver Disease, 1/1/2014
• Short-term monotherapy with IDX184, a liver-targeted nucleotide polymerase inhibitor, in patients with chronic hepatitis C virus infection  
  Lalezari J, Asmuth D, Casiro A, Lawrence S, Dubuc-Patrick G, Chen J, McCarville J, Pietropaolo K, Zhou XJ, Sullivan-Bolyai J, Mayerse D, Antimicrob Agents Chemother, 1/1/2012
• Factors that predict response of patients with hepatitis C virus infection to boceprevir  
  Poordad F, Bronowicki JP, Gordon SC, Zeuzem S, Jacobson IM, Sulkowski MS, Poynard T, Morgan TR, Molony C, Pedicone LD, Sings HL, Burroughs MH, Sniukiene V, Boparai N, ..., Gastroenterology, 1/1/2012
• Boceprevir for untreated chronic HCV genotype 1 infection  
  Poordad F, McCone J Jr, Bacon BR, Bruno S, Manns MP, Sulkowski MS, Jacobson IM, Reddy KR, Goodman ZD, Boparai N, DiNubile MJ, Sniukiene V, Brass CA, Albrecht JK, Brono..., N Engl J Med, 1/1/2011
• PHOENIX: A randomized controlled trial of peginterferon alfa-2a plus ribavirin as a prophylactic treatment after liver transplantation for hepatitis C virus  
  Bzowej N, Nelson DR, Terrault NA, Everson GT, Teng LL, Prabhakar A, Charlton MR, PHOENIX Study Group, Liver Transpl, 1/1/2011
• Telaprevir for previously untreated chronic hepatitis C virus infection  
  Jacobson IM, McHutchison JG, Dusheiko G, Di Bisceglie AM, Reddy KR, Bzowej NH, Marcellin P, Muir AJ, Ferenci P, Flisiak R, George J, Rizzetto M, Shouval D, Sola R, Ter..., N Engl J Med, 1/1/2011
• Response-guided telaprevir combination treatment for hepatitis C virus infection  
  Sherman KE, Flamm SL, Afdhal NH, Nelson DR, Sulkowski MS, Everson GT, Fried MW, Adler M, Reesink HW, Martin M, Sankoh AJ, Adda N, Kauffman RS, George S, Wright CI, Poo..., N Engl J Med, 1/1/2011
• Liver transplant case report: Transgenderism and liver transplantation  
  Martin KA, Bostwick JM, International Journal of Transgenderism, 1/1/2011
• Peginterferon alfa-2a and ribavirin in Latino and non-Latino whites with hepatitis C  
  Rodriguez-Torres M, Jeffers LJ, Sheikh MY, Rossaro L, Ankoma-Sey V, Hamzeh FM, Martin P, Latino Study Group, N Engl J Med, 1/1/2009
• Telaprevir with peginterferon and ribavirin for chronic HCV genotype 1 infection  
  McHutchison JG, Everson GT, Gordon SC, Jacobson IM, Sulkowski M, Kauffman R, McNair L, Alam J, Muir AJ, PROVE1 Study Team, N Engl J Med, 1/1/2009
• A randomized, prospective, double-blind, placebo-controlled trial of terlipressin for type 1 hepatorenal syndrome  
  Sanyal AJ, Boyer T, Garcia-Tsao G, Regenstein F, Rossaro L, Appenrodt B, Blei A, Gulberg V, Sigal S, Teuber P, Terlipressin Study Group, Gastroenterology, 1/1/2008
• Introducing THE corner  
  Vargas HE, Liver Transpl, 1/1/2007
• Portal vein thrombosis  
  Rodriguez-Luna H, Vargas HE, Current Treatment Options in Gastroenterology, 1/1/2007
• Distal splenorenal shunt versus transjugular intrahepatic portal systematic shunt for variceal bleeding: a randomized trial  
  Henderson JM, Boyer TD, Kutner MH, Galloway JR, Rikkers LF, Jeffers LJ, Abu-Elmagd K, Connor J, DIVERT Study Group, Gastroenterology, 1/1/2006
• Recurrent hepatitis C virus after liver transplantation: The role of quasispecies complexity and diversity  
  Gallegos-Orozco JF, Vargas HE, Curr Opin Organ Transplant, 1/1/2004
• Analysis Of 5’UTR And E2 Region Quasispecies In Liver Transplantation  
  Arenas JI Fasola CG Rakela J Wilkinson JK, Laskus T, Klintmalm G, Gastroenterology, 1/1/2002
• Is D-penicillamine useful in fulminat Wilson's disease?  
  Rakela J, Arenas J, Liver Transpl, 1/1/2002
• Clinical and virological response of hepatitis B and C viral co-infection after liver transplantation: effect of viral hepatitis D  
  Taniguchi M, Shakil AO, Laskus T, Demetris AJ, Gayowski T, Dodson SF, Fung JJ, Rakela J, Liver Transpl Surg, 1/1/2000
• Progression of liver fibrosis in patients with chronic hepatitis C after orthotopic liver transplantation: a final report  
  Chopra K, Demetris A, Blakolmer K, Dvorchick I, Laskus T, Wang LF, Araya V, Dodson F, Fung J, Rakela J, Hepatology, 1/1/1999
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Books/Book Chapters

• Gastroenterology and hepatology board review 
  Chapter: Drug-induced, granulomatous, and other inflammatory hepatic diseases 
  Page 389 - 398Gallegos-Orozco JF, Vargas HEEditors: DiBaise JK.McGraw-Hill Medical, New YorkEdition 3rd,2012
• Practical gastroenterology and hepatology. Liver and biliary disease 
  Talley NJ, Lindor KDWiley-Blackwell, Chichester; Hoboken2010
• Practical gastroenterology and hepatology. Liver and biliary disease 
  Chapter: Hepatic complications of bone marrow transplantation 
  Page 275 - 287Curtis KK, Slack JLEditors: Talley NJ; Lindor KD; Vargas HE.Wiley-Blackwell, Chichester; Hoboken2010
• Practical gastroenterology and hepatology. Liver and biliary disease 
  Chapter: Assessment of abnormal liver injury tests 
  Page 32 - 37Batheja MJ, Vargas HEEditors: Talley NJ; Lindor KD; Vargas HE.Wiley-Blackwell, Chichester; Hoboken2010
• Practical gastroenterology and hepatology. Liver and biliary disease 
  Chapter: Endoscopic techniques in management of the liver and biliary tree: upper gastrointestinal endoscopy 
  Page 55 - 60Vargas HEEditors: Talley NJ; Lindor KD; Vargas HE.Wiley-Blackwell, Chichester; Hoboken2010
• The interface of neurology & internal medicine 
  Chapter: Neurological problems seen during the management of the patient with viral hepatitis 
  Page 265 - 273Mai A, Vargas HEEditors: Biller J.Wolters Kluwer Health/Lippincott Wiliams & Wilkins, Philadelphia2008
• Transplante Hepático 
  Chapter: Métodos de Apoyo a la Función Hepática 
  Rodriguez-Luna H, Vargas HEEditors: Berenguer & Parrilla.Elsevier, Barcelona SpainEdition 2nd,2007
• Zakim and Boyer's Hepatology: A textbook of liver disease 
  Chapter: Portal and splenic vein thrombosis 
  Page 905 - 914Rodriguez-Luna H, Vargas HEEditors: Boyer TC, Wright TL, Manns MP.Elsevier Saunders, PhiladelphiaEdition 5th,2006
• Hepatology: A Textbook of Liver Disease 
  Chapter: Portal Vein Thrombosis 
  Rodriguez-Luna H, Vargas HEEditors: Boyer TD, Wright T, Mans M.Saunders, Philadelphia, PAEdition 4th,2005
• Portal hypertension: pathobiology, evaluation, and treatment 
  Chapter: Hepatic venous outflow obstruction: Budd-Chiari syndrome and veno-occlusive disease 
  Page 433 - 453Vargas HE, Boyer TDEditors: Sanyal AJ, Shah VH.Humana Press, Totowa2005
• Transplantation of the liver 
  Chapter: Monitoring and care of the patient before liver transplantation 
  Page 473 - 489Sharma P, Rakela JEditors: Busuttil RW, Klintmalm GB.Elsevier Saunders, PhiladelphiaEdition 2nd,2005
• Schiff's Diseases of the Liver 
  Chapter: Transjugular intrahepatic portasystemic shunts 
  Boyer TD, Vargas HEEditors: Schiff ER, Sorrell MF, Madrey WC.Lippincott Williams and Wilkins, Philadelphia, PAEdition 9th,2002
• In Hematopoietic Stem Cell Therapy 
  Chapter: Oral Mucositis And Gastrointestinal Complications 
  Vargas H, Silverman WPhiladelphia2000
• Surgical Technology International 
  Chapter: Intestinal Transplantation: Current Status and Latest Developments 
  Doria C, Giraldo M, Bueno J, Mazariegos G, Kocoshis S, Marino I, Demetris A, Fung JJ, Starzl TE, Reyes J, Abu-Elmagd1999
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Abstracts/Posters

• Changes in Tacrolimus Metabolism in Post-LT Recurrent HCV Treatment with DAA Regimens
  Vargas HE, Special Conference on Hepatitis C, American Association for the Study of Liver Diseases (AASLD)/European Association for the Study of the Liver (EASL), New York, NY, 1/1/2014
• Advances in HCV Therapy
  Vargas HE, Mayo Infection and Immunity Research Club, Rochester, MN, 1/1/2014
• The Child-Turcotte-Pugh (CTP) score is best at predicting 6-week mortality in patients with acute variceal hemorrhage (avh): analysis of a US multi-center prospective ...
  Fortune BE, Garcia-Tsao G, Ciarleglio M, Deng YH, Fallon MB, Sigal S, Chalasani NP, Lim JK, Reuben A, Abrams G, Lewis MB, Hassanein T, Trotter JF, Sanyal AJ, Beavers K..., Hepatology, 1/1/2014
• Multicenter experience using sofosbuvir and simeprevir with/without ribavirin to treat hcv genotype 1 after liver transplantation
  Pungpapong S, Werner KT, Aqel B, Leise MD, Murphy JL, Henry TM, Ryland K, Chervenak AE, Watt KD, Keaveny A, Hepatology, 1/1/2014
• The use of simeprevir and sofosbuvir to treat hcv g1 in the liver transplant setting: the experience in 3 US centers
  Aqel B, Pungpapong S, Werner KT, Chervenak AE, Rakela J, Watt KD, Leise MD, Murphy JL, Henry TM, Ryland K, Keaveny A, Hepatology, 1/1/2014
• High sustained virologic response rates in liver transplant recipients with recurrent hcv genotype 1 infection receiving abt-450/r/ombitasvir plus dasabuvir plus ribav...
  Mantry PS, Kwo PY, Coakley E, Te HS, Brown RS, Gordon FD, Levitsky J, Terrault N, Burton JR, Xie WG, Setze C, Badri P, Vilchez RA, Forns X, Hepatology, 1/1/2014
• Reversal of hepatorenal syndrome type 1 (hrs-1) with terlipressin plus albumin versus placebo plus albumin - not all responses are created equal - an analysis of the r...
  Sanyal AJ, Boyer TD, Frederick RT, Regenstein F, Rossaro L, Araya V, Reddy KR, Jamil K, Pappas SC, Hepatology, 1/1/2014
• Validation of the hepatitis aggressiveness score in a liver transplant population with recurrent hepatitis C
  Unzueta A, Moreira RK, DePetris G, Smith ML, Chang YHH, Cheng MR, Eyshou A, Gallegos-Orozco JF, Aqel B, Hepatology, 1/1/2014
• Safety and efficacy of sofosbuvir (sof) in combination with simeprevir (sim) plus ribavirin (rbv) in patients with genotype 1: interim results of a prospective, observ...
  Sulkowski MS, Di Bisceglie AM, Kuo A, Reddy KR, Lim JK, Morelli G, Feld JJ, Brown RS, Frazier LM, Fried MW, Nelson DR, Jacobson IM, Hepatology, 1/1/2014
• Treatment of hcv in the sof era: experience in difficult to treat patients in a US liver transplant center
  Werner KT, Chervenak AE, Hartel LA, Aqel B, Balan V, Byrne TJ, Carey EJ, Rakela J, Hepatology, 1/1/2014
• Prospective assessment of the abundance of drug metabolizing enzymes in the p450 pathway in patients with non alcoholic fatty liver disease (nafld)
  Aqel B, Langlais P, Carey EJ, Leonard M, Mandarino LJ, Hepatology, 1/1/2014
• Impact of electronic reminder to improve hepatitis C screening in age-appropriate patients: results of a pilot quality improvement intervention
  Byrne TJ, Carey EJ, Aqel B, Douglas DD, Timm V, Dosmann M, Whitten P, White MR, Rakela J, Hepatology, 1/1/2014
• M12-999:abt-450/r/abt-267+abt-333+ribavirin in liver transplant recipients with recurrent hcv genotype 1 infection
  Mantry P, Kwo P, Coakley E, Te H, Brown R Jr, Gordon F, Levitsky J, Terrault N, Burton J Jr, Xie W, Setze C, Badri P, Vilchez R, Forns X, Am J Transplant, 1/1/2014
• Prospective analysis of predictors of new onset diabetes after liver transplantation
  Reynolds J, Chang Y, Chakkera H, Aqel B, Byrne T, Douglas D, Moss A, Carey E, Am J Transplant, 1/1/2014
• M12-999:abt-450/r/abt-267+abt-333+ribavirin in liver transplant recipients with recurrent hcv genotype 1 infection
  Mantry P, Kwo P, Coakley E, Te H, Brown R Jr, Gordon F, Levitsky J, Terrault N, Burton J Jr, Xie W, Setze C, Badri P, Vilchez R, Forns X, Transplantation, 1/1/2014
• Prospective analysis of predictors of new onset diabetes after liver transplantation
  Reynolds J, Chang Y, Chakkera H, Aqel B, Byrne T, Douglas D, Moss A, Carey E, Transplantation, 1/1/2014
• Safety and efficacy of new DAA-based therapy for hepatitis C post-transplant: interval results from the HCV-TARGET longitudinal, observational study
  Brown RS, Reddy KR, O'Leary JG, Kuo A, Morelli G, Stravitz RT, Durand CM, Di Bisceglie AM, et al., AASLD, Boston, MA, 1/1/2014
• Preliminary experience utilizing boceprevir with pegylated interferon and ribavirin for treatment of recurrent hepatitis C genotype 1 after liver transplantation
  Aqel B, Carey E, Douglas D, Byrne T, Rakela J, Susan W, Am J Transplant, 1/1/2013
• Twice daily telaprevir in combination with peginterferon alfa-2a/ribavirin in hcv genotype 1 liver transplant recipients: interim safety/efficacy of the refresh study
  Brown R, Russo M, Levitsky J, Brown K, Fontana R, Yoshida E, Bsharat M, Rubin R, Am J Transplant, 1/1/2013
• Twice daily telaprevir in combination with peginterferon alfa-2a/ribavirin in hcv genotype 1 liver transplant recipients: interim pharmacokinetics of the refresh study
  Dai Y, Brown K, Russo M, Yoshida E, Fontana R, Levitsky J, Rubin R, Garg V, Brown R, Am J Transplant, 1/1/2013
• Six minute walk distance enhances pre-operative evaluation in candidates for liver transplantation
  Yadav A, Chang Y, Carpenter S, Silva A, Aqel B, Byrne T, Douglas D, Carey E, Liver Transpl, 1/1/2013
• Vitamin d deficiency and six minute walk distance in candidates listed for liver transplantation
  Yadav A, Chang Y, Carpenter S, Silva A, Aqel B, Byrne T, Douglas D, Carey E, Liver Transpl, 1/1/2013
• Six minute walk distance predicts waitlist mortality more accurately than sarcopenia in liver transplant candidates
  Yadav A, Chang YHH, Silva AC, Aqel B, Byrne TJ, Douglas DD, Carey EJ, Hepatology, 1/1/2013
• Twice-daily telaprevir in combination with peginterferon alfa-2a/ribavirin in genotype 1 hcv liver transplant recipients: interim week 16 calcineurin inhibitor, telapr...
  Fontana RJ, Qiu RL, Russo MW, Yoshida EM, Brown KA, Levitsky J, Rubin RA, Garg V, Brown RS, Hepatology, 1/1/2013
• Morbidity and mortality following radiofrequency- and microwave ablation in patients with hepatocellular carcinoma
  Boyle SS, Aqel B, Carey EJ, Douglas DD, Rakela J, Byrne TJ, Hepatology, 1/1/2013
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Lectures

• Current and Future Management of Prior Difficult-to-Treat HCV Patients 
  Houston, TX - 1/1/2015
• Debate: Treat All Stages of Fibrosis of Chronic-HCV Now! 
  Houston, TX - 1/1/2015
• 2014: The Year HCV Treatment Came of Age: Implications for the LT Population 
  Mayo Clinic, Phoenix, AZ - 1/1/2014
• Difficult to Treat Patients in 2014: Opportunities 
  University of Utah, Salt Lake City, UT - 1/1/2014
• HCV Treatment for 2014: The New Direct Anti-virals 
  Scottsdale, AZ - 1/1/2014
• General Hepatology 
  Orlando, FL - 1/1/2014
• Hepatitis C Management 
  Orlando, FL - 1/1/2014
• General Hepatology Q & A 
  Orlando, FL - 1/1/2014
• Challenges in Hepatitis B and C 
  Orlando, FL - 1/1/2014
• Lo Mejor of DDW en Español 
  Chicago, IL - 1/1/2014
• How to Treat the Patient with Hepatitis C in 2014 
  Mayo Clinic, Phoenix, AZ - 1/1/2014
• Acute Hepatitis C 
  Monterrey, Mexico - 1/1/2014
• Hepatitis C: Therapy without Interferon 
  Monterrey, Mexico - 1/1/2014
• Hepatitis: Question and Answer Session 
  Monterrey, Mexico - 1/1/2014
• Presentation of Clinical Cases 
  Monterrey, Mexico - 1/1/2014
• Preparation of the Cirrhotic Patient for Gastrointestinal Endoscopy, Session I: Endoscopy in Patients with Advanced Liver Disease 
  Boston, MA - 1/1/2014
• Multicenter Experience using Sofosbuvir and Simeprevir with/without Ribavirin to Treat HCV Genotype 1 after Liver Transplantation 
  Boston, MA - 1/1/2014
• The Use of Simeprevir and Sofosbuvir to Treat HCV G1 in the Liver Transplant Setting: The Experience in 3 U.S. Centers, Parallel 2: Antivirals, Acute Liver Failure in ... 
  Boston, MA - 1/1/2014
• Parallel 12: Hepatitis C: New Agents - Part 1 
  Boston, MA - 1/1/2014
• High Sustained Virologic Response Rates in Liver Transplant Recipients with Recurrent HCV Genotype 1 Infection Receiving ABT-450/r/Ombitasvir+Dasabuvir Plus Ribavirin 
  Boston, MA - 1/1/2014
• Hepatitis C Update 
  Mayo Clinic, Phoenix, AZ - 1/1/2013
• Difficult Decisions in the Treatment of Viral Hepatitis C 
  Veracruz, Mexico - 1/1/2013
• Hepatitis C: What to Do When the Treatment Fails 
  Las Vegas, NV - 1/1/2011
• Sindrome Metabolico y Trasplante 
  Medellin, Colombia - 1/1/2011
• HCV Que Hacer para Facilitar Requesta Viral Sostenida 
  Medellin, Colombia - 1/1/2011
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