Overview of Dr. Worman
Dr. Howard Worman is a physician-scientist in New York, NY. He is Professor of Medicine and Pathology and Cell Biology at Columbia University and an Attending Physician at NewYork-Presbyterian Hospital/Columbia University Irving Medical Center. He received his BA from Cornell University and MD from University of Chicago Division of the Biological Sciences The Pritzker School of Medicine. Dr. Worman is an internist who specializes in hepatology. His research is focused on genetic disorders caused by mutations in genes encoding nuclear envelope proteins and liver diseases including nonalcoholic steatohepatitis and primary biliary cirrhosis.
Office
161 Fort Washington Avenue
New York, NY 10032
Education & Training
- Icahn School of Medicine at Mount SinaiPost-Doctoral Fellowship, Transplant Hepatology, 1990 - 1991
- The Rockeller UniversityPost-Doctoral Fellowship, 1987 - 1990
- New York Presbyterian Hospital (Cornell Campus)Residency, Internal Medicine, 1985 - 1987
- University of Chicago Division of the Biological Sciences The Pritzker School of MedicineClass of 1985
- Cornell UniversityBA, Chemistry and Biology, Cum Laude, 1977 - 1981
Certifications & Licensure
- NY State Medical License 1986 - 2025
- IL State Medical License 2003 - 2005
- American Board of Internal Medicine Internal Medicine
Awards, Honors, & Recognition
- Elected Member Association of American Physicians, 2010
- Elected Member The American Society for Clinical Investigation, 1998
- Silberberg Award Columbia University College of Physicians and Surgeons, 1995
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Publications & Presentations
PubMed
- 50 citationsDefective Lamin A-Rb Signaling in Hutchinson-Gilford Progeria Syndrome and Reversal by Farnesyltransferase InhibitionJackleen Marji, Seán I. O'Donoghue, Dayle McClintock, Venkata P. Satagopam, Reinhard Schneider
Plos One. 2010-06-15 - 49 citationsTorsinA controls TAN line assembly and the retrograde flow of dorsal perinuclear actin cables during rearward nuclear movementCosmo A. Saunders, Nathan J. Harris, Patrick T. Willey, Brian M. Woolums, Yuexia Wang
The Journal of Cell Biology. 2017-03-06 - 96 citationsTAN lines: a novel nuclear envelope structure involved in nuclear positioning.G. W. Gant Luxton, Edgar R. Gomes, Eric S. Folker, Howard J. Worman, Gregg G. Gundersen
Nucleus. 2011-05-01
Journal Articles
- Cell signaling abnormalities in cardiomyopathy caused by lamin A/C gene mutationsWorman, H. J., Biochem. Soc. Trans., 1/1/2018
- Gunter Blobel: Pioneer of molecular cell biology (1936�2018)Blobel Laboratory Trainees (authors in footnote), J. Cell Biol., 1/1/2018
- Permanently farnesylated prelamin A, progeria and atherosclerosisWorman, H. J. and Michaelis, S., Circulation, 1/1/2018
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Books/Book Chapters
Lectures
- Entertaining Science: From Nuclear Membranes to Aging�What a Long, Strange Trip It�s BeenThe Cornelia Street Cafe, New York, NY - 1/1/2018
- Biomedical Research in the Next DecadeNew York, NY - 1/1/2018
- A Precision Medicine Approach to the LaminopathiesMultiple locations, 2016, 2017 - 1/1/2017
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Other
- Computers and technology: creating a websiteWorman, H. J., AGA News
1/1/1997 - Electronic prescription services offer potential savings and improvements in efficienciesWeinstein, D. R. and Worman, H. J., AGA News
1/1/1997 - Military AIDS tests can't be conclusive (letter)Worman, H. J., The New York Times
1/28/1985 - Join now to see all
Press Mentions
- Kids with Rare Rapid-Aging Disease Get Hope from Study DrugApril 24th, 2018
- Unorthodox Study Claims Drug Prolongs Lives of Children with Premature Aging DiseaseMay 8th, 2014
- Progeria Drug Prospect FoundMay 2nd, 2014
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Grant Support
- The Nucleocytoskeleton In Progeria And AgingEunice Kennedy Shriver National Institute Of Child Health &Human Development2011–2012
- Nucleocytoplasmic Interactions And Dynamics In Emery-Dreifuss Muscular DystrophyNational Institute Of Neurological Disorders And Stroke2007–2011
- Pathogenesis Of Emery-Dreifuss Muscular DystrophyNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2003–2011
- Lamin A Mutation And Hutchinson-Gilford ProgeriaNational Institute On Aging2006–2008
- Dux4 And Facioscapulohumeral Muscular DystrophyNational Institute Of Neurological Disorders And Stroke2003–2004
- Lamin A In Adipocyte Differentation And SurvivalNational Institute Of Diabetes And Digestive And Kidney Diseases2003–2004
- Ribavirin PLUS Interferon Alpha-2b In Treatment Of Chronic Hepatitis CNational Center For Research Resources1998–2002
- Pathobiology Of The Nuclear Envelope In CancerNational Cancer Institute1996–2000
- Characterization Of Nuclear Pore Complex ProteinsNational Institute Of Diabetes And Digestive And Kidney Diseases1990–1991
- Characterization Of Nuclear Pore Complex ProteinsNational Institute Of Diabetes And Digestive And Kidney Diseases1987–1989
Research History
- ProfessorDepartment of Medicine and Department of Pathology and Cell Biology, Columbia University, New York, NY2007 - Present
- Associate Professor (Tenured 2001)Department of Medicine and Department of Anatomy and Cell Biology, Columbia University, New York, NY1998 - 2007
- Assistant ProfessorDepartment of Medicine and Department of Anatomy and Cell Biology, Columbia University, New York, NY1995 - 1998
- Assistant ProfessorDepartment of Medicine and Department of Molecular Biology, Mount Sinai School of Medicine, New York, NY1990 - 1994
- Postdoctoral FellowLaboratory of Cell Biology (Günter Blobel, Lab Head), Rockefeller University, New York, NY1987 - 1990
Professional Memberships
- Member
- American Association for the Study of Liver DiseasesMember
- American Society for Cell BiologyMember
- American Society for Clinical InvestigationMember
- Association of American PhysiciansMember
Industry Relationships
- Scientific Advisory Board, AlloMek Therapeutics2015 - Present
- Board of Directors, Epiphany Biosciences, Inc.2009 - Present
- Scientific Advisory Board, Epiphany Biosciences, Inc2007 - Present
- Scientific Advisory Board, MNG Laboratories2017 - 2018
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