Howard J Aizenstein MD
Professor of Psychiatry and Associate Professor of Bioengineering, and Clinical and Translational Science, University of Pittsburgh.
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3811 O'Hara StreetSuite 274Pittsburgh, PA 15213
Phone+1 412-246-5325
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Education & Training
UPMC Medical EducationFellowship, Geriatric Psychiatry, 1999 - 2000- UPMC Medical EducationResidency, Psychiatry, 1995 - 1999
University of Illinois College of MedicineClass of 1995
Certifications & Licensure
PA State Medical License 1996 - 2026
American Board of Psychiatry and Neurology Psychiatry- American Board of Psychiatry and Neurology Geriatric Psychiatry
Clinical Trials
- Determining Changes in Brain Structure Associated With Symptoms of Late-life Depression Start of enrollment: 2005 Aug 01
- Enhancing Rehabilitation After Stroke Start of enrollment: 2009 Mar 01
- Neural Mechanisms of Monoaminergic Engagement in Late-life Depression Treatment Response (NEMO) Start of enrollment: 2017 May 24
Publications & Presentations
PubMed
- Correlating hippocampal and amygdala volumes with neuropathological burden in Down syndrome and Alzheimer's disease and related neurodegenerative pathologies using 7T ...Jr-Jiun Liou, Jinghang Li, Jacob Berardinelli, Hecheng Jin, Tales Santini
Journal of Neuropathology and Experimental Neurology. 2025-03-10 - Altered triple network model connectivity is associated with cognitive function and depressive symptoms in older adults.Antonija Kolobaric, Carmen Andreescu, Andrew R Gerlach, Eldin Jašarević, Howard Aizenstein
Alzheimer's & Dementia. 2025-03-01 - Beyond Traditional Statistical Methods: Considerations for Developing and Evaluating Machine Learning-Based Clinical Prediction Models.Adam Ciarleglio, Howard Aizenstein
The American Journal of Geriatric Psychiatry. 2025-03-01
Journal Articles
- Genome-Wide Association Study of Brain Amyloid Deposition as Measured by Pittsburgh Compound-B (PiB)-PET ImagingOscar L Lopez, Andrew J Saykin, Howard J Aizenstein, William E Klunk, Beth E Snitz, Nature
Lectures
- The Relationship of Current Cognitive Activity to Brain Amyloid-Beta Burden and Glucose MetabolismPittsburgh, PA - 6/16/2014
- The Relationship of Current Cognitive Activity to Brain Amyloid-Beta Burden and Glucose MetabolismPittsburgh, PA - 6/16/2014
- The Relationship of Current Cognitive Activity to Brain Amyloid-Beta Burden and Glucose MetabolismPittsburgh, PA - 6/14/2014
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Authored Content
- Association of Hippocampal Substructure Resting-State Functional Connectivity with Memory Performance in Older AdultsMarch 2018
Press Mentions
New Pitt Bioengineering in Psychiatry Training Program Receives ~$1.1M from NIH T32July 10th, 2019
Preventive Neuroradiology: Brain Imaging Bolsters Efforts to Lower Alzheimer's RiskJune 4th, 2015- Predicting Alzheimer’s Dementia in Oldest of the OldDecember 24th, 2023
Grant Support
- 7T Vascular and Molecular Imaging of SVD: Sex, Equol, and Risk of Alzheimer’s DiseaseUNIVERSITY OF PITTSBURGH AT PITTSBURGH2024–2029
- 7T Vascular and Molecular Imaging of SVD: Sex, Equol, and Risk of Alzheimer’s DiseaseUNIVERSITY OF PITTSBURGH AT PITTSBURGH2024–2029
- 7T Vascular and Molecular Imaging of SVD: Sex, Equol, and Risk of Alzheimer’s DiseaseUNIVERSITY OF PITTSBURGH AT PITTSBURGH2024–2029
- 7T Vascular and Molecular Imaging of SVD: Sex, Equol, and Risk of Alzheimer’s DiseaseUNIVERSITY OF PITTSBURGH AT PITTSBURGH2024–2029
- 7T Vascular and Molecular Imaging of SVD: Sex, Equol, and Risk of Alzheimer’s DiseaseUNIVERSITY OF PITTSBURGH AT PITTSBURGH2024–2029
- 7T Vascular and Molecular Imaging of SVD: Sex, Equol, and Risk of Alzheimer’s DiseaseUNIVERSITY OF PITTSBURGH AT PITTSBURGH2024–2029
- Advanced Research Institute (ARI) in Mental Health and AgingUNIVERSITY OF PITTSBURGH AT PITTSBURGH2019–2029
- Advanced Research Institute (ARI) in Mental Health and AgingUNIVERSITY OF PITTSBURGH AT PITTSBURGH2019–2029
- Advanced Research Institute (ARI) in Mental Health and AgingUNIVERSITY OF PITTSBURGH AT PITTSBURGH2019–2029
- Advanced Research Institute (ARI) in Mental Health and AgingUNIVERSITY OF PITTSBURGH AT PITTSBURGH2019–2029
- Advanced Research Institute (ARI) in Mental Health and AgingUNIVERSITY OF PITTSBURGH AT PITTSBURGH2019–2029
- Advanced Research Institute (ARI) in Mental Health and AgingUNIVERSITY OF PITTSBURGH AT PITTSBURGH2019–2029
- Brain mitochondrial PET imaging and 31P-MR spectroscopy to dissect the role of mitochondrial dysfunction in bioenergetic dysregulation in Dementia with Lewy Bodies pathogenesisUNIVERSITY OF PITTSBURGH AT PITTSBURGH2023–2028
- The role of astrogliosis in aging and the pathological and clinical progression of Alzheimer's DiseaseUNIVERSITY OF PITTSBURGH AT PITTSBURGH2004–2027
- Clinical and Translational Research Training in Geriatric Mental HealthUNIVERSITY OF PITTSBURGH AT PITTSBURGH1997–2027
- Clinical and Translational Research Training in Geriatric Mental HealthUNIVERSITY OF PITTSBURGH AT PITTSBURGH1997–2027
- Clinical and Translational Research Training in Geriatric Mental HealthUNIVERSITY OF PITTSBURGH AT PITTSBURGH1997–2027
- Clinical and Translational Research Training in Geriatric Mental HealthUNIVERSITY OF PITTSBURGH AT PITTSBURGH1997–2027
- Clinical and Translational Research Training in Geriatric Mental HealthUNIVERSITY OF PITTSBURGH AT PITTSBURGH1997–2027
- Clinical and Translational Research Training in Geriatric Mental HealthUNIVERSITY OF PITTSBURGH AT PITTSBURGH1997–2027
- Roles of Gray Matter Brain Aging and Small Vessel Disease in AD PathophysiologyUNIVERSITY OF PITTSBURGH AT PITTSBURGH2005–2026
- Imaging Advancements in Small Vessel and CSF Flow Pathophysiology of Pre-clinical Alzheimer's DiseaseUNIVERSITY OF PITTSBURGH AT PITTSBURGH2019–2025
- Bioengineering in Psychiatry Training ProgramUNIVERSITY OF PITTSBURGH AT PITTSBURGH2019–2025
- Resilience To Mobility Impairment: Neural Correlates And Protective FactorsNational Institute On Aging2011–2012
- Pharmacologic MRI Predictors Of Treatment Response In Late-Life DepressionNational Institute Of Mental Health2011
- Altered Functioning Of Cognitive And Affective Circuits In Late-Life DepressionNational Institute Of Mental Health2007–2010
- Cognitive And Affective Circuits In Late-Life DepressionNational Institute Of Mental Health2006
- Predictors Of Treatment Response In Late-Life DepressionNational Institute Of Mental Health2002–2006
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