Hong Wu MD

PubMed

• 4 citations
  A Retrospective, Observational Analysis of Tumor Infiltrating Lymphocytes and Tumor Regression in Melanoma.
  Angela Zaladonis, Jeffrey M. Farma, Maureen V. Hill, Meghan Hotz, Karli Meller
  The Journal of Surgical Research. 2021-06-18
• 2 citations
  Impact of Sun Exposure and Tanning Patterns on Next-Generation Sequencing Mutations in Melanoma.
  Kimberly Loo, Iman Soliman, Madelyn Renzetti, Tianyu Li, Hong Wu
  The Journal of Surgical Research. 2020-10-01
• 5 citations
  Primary tumor characteristics and next-generation sequencing mutations as biomarkers for melanoma immunotherapy response.
  Kimberly Loo, Gabrielle Gauvin, Iman Soliman, Madelyn Renzetti, Mengying Deng
  Pigment Cell & Melanoma Research. 2020-07-07

Journal Articles

• Human Tumor Genomics and Zebrafish Modeling Identify SPRED1 Loss as a Driver of Mucosal Melanoma  
  Hong Wu, Richard C Jordan, Boris C Bastian, Leonard I Zon, Iwei Yeh, Science Magazine
• ATG5 Mediates a Positive Feedback Loop between Wnt Signaling and Autophagy in Melanoma  
  Ndoye A, Budina-Kolomets A, Kugel CH 3rd, Webster MR, Kaur A, Behera R, Rebecca VW, Li L, Brafford PA, Liu Q, Gopal YNV, Davies MA, Mills GB, Xu X, Wu H, Herlyn M, Nic..., Cancer Res, 1/1/2017
• Oncogene-Expressing Senescent Melanocytes Up-Regulate MHC Class II, a Candidate Melanoma Suppressor Function  
  van Tuyn J, Jaber-Hijazi F, MacKenzie D, Cole JJ, Mann E, Pawlikowski JS, Rai TS, Nelson DM, McBryan T, Ivanov A, Blyth K, Wu H, Milling S, Adams PD, J Invest Dermatol, 1/1/2017
• Acute Inhibition of MEK Suppresses Congenital Melanocytic Nevus Syndrome in a Murine Model Driven by Activated NRAS and Wnt Signaling  
  Pawlikowski JS, Brock C, Chen SC, Al-Olabi L, Nixon C, McGregor F, Paine S, Chanudet E, Lambie W, Holmes WM, Mullin JM, Richmond A, Wu H, Blyth K, King A, Kinsler VA, ..., J Invest Dermatol, 1/1/2015
• The utility of MYC and FLT4 in the diagnosis and treatment of postradiation atypical vascular lesion and angiosarcoma of the breast  
  Cornejo KM, Deng A, Wu H, Cosar EF, Khan A, St Cyr M,Tomaszewicz K, Dresser K, O'Donnell P, Hutchinson L, Hum Pathol, 1/1/2015
• Mitotic Stress Is an Integral Part of the Oncogene-Induced Senescence Program that Promotes Multinucleation and Cell Cycle Arrest  
  Dikovskaya D, Cole JJ, Mason SM, Nixon C, Karim SA, McGarry L, Clark W, Hewitt RN, Sammons MA, Zhu J, Athineos D, Leach JD, Marchesi F, van Tuyn J, Tait SW, Brock C, M..., Cell Rep, 1/1/2015
• Surgery and Adjuvant Radiation for High-risk Skin Adnexal Carcinoma of the Head and Neck  
  Wang LS, Handorf EA, Wu H, Liu JC, Perlis CS, Galloway TJ, Am J Clin Oncol, 1/1/2015
• Bilateral granulosa cell tumors: a novel malignant manifestation of multiple endocrine neoplasia 1 syndrome found in a patient with a rare menin in-frame deletion  
  Hall MJ, Innocent J, Rybak C, Veloski C, Scott WJ, Wu H, Ridge JA, Hoffman JP, Borghaei H, Turaka A, Daly MB, Application of Clinical Genetics, 1/1/2015
• Inhibitor of DNA Binding 4 (ID4) is Highly Expressed in Human Melanoma Tissues and May Function to Restrict Normal Differentiation of Melanoma Cells  
  Y Peretz, H Wu, S Patel, A Bellacosa and RA Katz, PLoS One, 1/1/2015
• Tumor Infiltrating Lymphocytes and their Role as a Prognostic Indicator for Melanoma  
  Reddy, SS, S Boukovalas, V Barnica, F Zhu, H Wu and JM. Farma, J Surg, 1/1/2014
• Absolute lymphocyte count: a potential prognostic factor for Merkel cell carcinoma  
  Johnson ME, Zhu F, Li T, Wu H, Galloway TJ, Farma JM, Perlis CS, Turaka A, J Am Acad Dermatol, 1/1/2014
• Antitumor response of an ERBB2 amplified inflammatory breast carcinoma with EGFR mutation to the EGFR-TKI erlotinib  
  Ali SM, Alpaugh RK, Buell JK, Stephens PJ, Yu JQ, Wu H, Hiemstra CN, Miller VA, Lipson D, Palmer GA, Ross JS, Cristofanilli M, Clin Breast Cancer, 1/1/2014
• Response of an ERBB2 mutated Inflammatory Breast Carcinoma to HER2-targeted Therapy  
  Ali SM, Alpaugh RK, Downing SR, Stephens PJ, Yu JQ, Wu H, Buell JK, Miller VA, Lipson D, Palmer GA, Ross JS & M Cristofanilli, J Clin Oncology, 1/1/2014
• Whole exome sequence analysis of serous borderline tumors of the ovary  
  Boyd J, Biao L, Suraj P, Wirchansky B, Hughes L, Forsythe C, and H Wu, Gyn Onc, 1/1/2013
• Lysosome-mediated processing of chromatin in senescence  
  Ivanov A, Pawlikowski J, Manoharan I, Rai TS, Nelson DM, Shah P, Wu H, Berger S, and Adams PD, Journal Cell Biology, 1/1/2013
• A Better Prognosis for Merkel Cell Carcinoma of Unknown Primary Origin  
  Chen KT, Papavasiliou P, Edwards K, Zhu F, Perlis C, Wu H, Turaka A, Berger A, JM Farma, Am J Surg, 1/1/2013
• Topical Chemotherapy in Cutaneous T-cell Lymphoma: Positive Results of a Randomized, Controlled, Multi-center Trial Testing the Efficacy and Safety of a Novel 002% Mec...  
  SR. Lessin, M Duvic, J Guitart, AG. Pandya, BE. Strober, EA. Olsen, CM. Hull, EH. Knobler, AH. Rook, EJ. Kim, MF. Naylor, DM. Adelson, AB. Kimball, GS. Wood, U Sundram..., Arch Derm, 1/1/2013
• Suppression of Nucleotide Metabolism Underlies the Establishment and Maintenance of Oncogene-Induced Senescence  
  Aird KM, Zhang G, Li H, Tu ZG, Bitler BG, Garipov A, Wu H, Wei Z, Wagner SN, Herlyn M and RG Zhang, Cell Reports, 1/1/2013
• Multicolor microRNA FISH effectively differentiates tumor types  
  Renwick N, Cekan P, Masry PA, McGeary SE, Miller JB, Hafner M, Li Z, Mihailovic A, Morozov P, Brown M, Gogakos T, Mobin MB, Snorrason EL, Feilotter HE, Zhang X, Perli..., J Clin Investigation, 1/1/2013
• The Specificity and Patterns of Staining in Human Cells and Tissues of p16INK4a Antibodies Demonstrate Variant Antigen Binding  
  Sawicka M, Pawlikowski J, Wilson S, Ferdinando D, Wu H, Adams PD, Gunn DA, Parish W, PLoS One, 1/1/2013
• Wnt signaling potentiates nevogenesis  
  Pawlikowski J, McBryan T, King A, Maier AB, Blyth K, Wu H, and Adams PD, PNAS, 1/1/2013
• SUZ12 promotes human epithelial ovarian cancer by suppressing apoptosis via silencing HRK  
  H Li, Q Cai, H Wu, V Vathipadiekal, ZC Dobbin, T Li, X Hua, CN Landen , MJ. Birrer, M Sanchez-Beato, R Zhang, Mol Cancer Res, 1/1/2012
• Carcinosarcoma of female urethra with melanocytic differentiation  
  Liu, J & H Wu, Int J Clin Exp Pathol, 1/1/2011
• Wnt5a Suppresses Epithelial Ovarian Cancer by Promoting Cellular Senescence  
  Bitler BG, Nicodemus JP, Li H, Cai Q, Wu H, Hua X, Li T, Birrer MJ, Godwin AK, Cairns P & R Zhang, Cancer Research, 1/1/2011
• Cytoskeleton alterations in melanoma: Aberrant expression of cortactin, an actin-binding adapter protein, correlates with melanocytic tumor progression (cover illustra...  
  Xu X-Z, Garcia MV, Li T-Y, Khor L-Y, Gajapathy, RS, Spittle C, Weed S, Lessin SR, H Wu, Mod Path, 1/1/2010
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Books/Book Chapters

• Dermatology 
  Chapter: Cutaneous Metastases. 
  Zook, MB, Wu H and SR LessinBologniaEdition 3rd,2012
• Sternberg�s Diagnostic Surgical Pathology. 
  Chapter: Localized Diseases of the Bronchi and Lung. 
  Patchefksy A, Ehya H., and H WuLippocott2005
• Endocrine Pathology. 
  Chapter: Merkel cell carcinoma. Chapter 11 
  Wu H, Elenistsas R, Zhang P, and DE ElderEditors: LiVolsi & Asa.Churchill Livingston, Philadelphia, PA2002

Lectures

• History of Blistering Sunburn and Molecular Profile in Melanoma. 
  Jacksonville, FL - 1/30/2018
• Molecular Profiling in Patients with Nodular verus Superficial Spreading Melanoma 
  Jacksonville, FL - 1/30/2018
• Smoking and Next Generation Sequencing Mutation Signature in Melanoma. 
  Jacksonville, FL - 1/30/2018
• Molecular Profiling in Melanoma: Does Age Make a Difference. 
  Las Vegas, NV - 1/1/2017
• Comparing Pathological T Stage with Next Generation Sequencing in Melanoma. 
  Las Vegas, NV - 1/1/2017
• Evaluation of Molecular Profile in High Risk Class 2 MelanomaDx Melanoma Patients. 
  Las Vegas, NV - 1/1/2017
• Molecular Profiling and Primary Location of Melanoma: Experience at an NCI-Designated Cancer Center. 
  Las Vegas, NV - 1/1/2017
• Skin Adnexal Carcinoma Arising in a Poroid Hidradenoma (Hidradenocarcinoma): A case Report. 
  Harrisburg, PA - 1/1/2017
• A Prospective, Multi-Institutional Assessment of Four Assays for PD-L1 Expression in NSCLC by Immunohistochemistry. 
  1/1/2016
• Molecular Profiling in Malignant Melanoma: initial experience at an NCI-designated cancer center. 
  Houston, TX - 1/1/2015
• Molecular markers in malignant melanoma: experience at an NCI-designated cancer center. 
  New York, NY - 1/1/2015
• Lymph Node Staging for Mucosal Melanoma. 
  1/1/2014
• Presence and Clinical Significance of Polyomavirus in Merkel Cell Carcinoma of Unknown vs. Known Primary Cutaneous Origin. 
  San Diego, CA - 1/1/2014
• Surgery and Adjuvant Radiation Provides Excellent Control Of Advanced, High Grade Skin Adnexal Carcinoma Of The Head And Neck. 
  Scottsdale, AZ - 1/1/2014
• Malignant melanoma with concordant loss of s100 and melanoma differentiation antigens. 
  1/1/2013
• MYC and FLT4 Expression in Post-Radiation Atypical Vascular Lesion and Angiosarcoma of the Breast. 
  Orlando, FL - 1/1/2013
• High Mitotic Rates in Patients with Cutaneous Melanoma. 
  1/1/2013
• Role of chemotherapy for Merkel cell carcinoma: a single institution experience. 
  1/1/2012
• Distinct modes of in vivo cellular senescence linked to tissue aging and development of melanocytic nevi. Mechanisms & Models of Cancer. 
  1/1/2012
• Merkel Cell Carcinoma and Sentinel Lymph Node Evaluation: Outcomes from a Single Institution. 
  1/1/2011
• The Role of Adjuvant Radiotherapy in Merkel Cell Carcinoma: A 20-year Experience at Fox Chase Cancer Center. 
  1/1/2011
• Distinct modes of in vivo cellular senescence linked to tissue aging and development of melanocytic nevi. 
  1/1/2011
• Prognostic significance of host immune factors in melanoma. 
  1/1/2011
• A Randomized, Pivotal Trial to Evaluate the Safety and Efficacy of 0.02% Nitrogen Mustard (NM) Formulations in Patients with Stage I or IIa Mycosis Fungoides (MF). 
  1/1/2010
• Utilization of flow cytometry in skin lymphoid lesions. 
  1/1/2010
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Other

• Dissertation: Characterization of cortactin (p80/85), an actin-binding pp60src substrate. 
  Wu H
  University of Virginia, Charlottesville, VA - 1/1/1992