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Office
4100 John R St
Detroit, MI 48201Phone+1 313-576-8709
Summary
- Dr. Hirva Mamdani is a medical oncologist specializing in treatment of thoracic malignancies, including lung cancer, mesothelioma, and esophageal cancer. She is affiliated with Karmanos Cancer Institute - an NCI designated comprehensive cancer center. Dr. Mamdani received her medical degree from M.P. Shah Medical College in India. She completed her residency from Wayne State University, Detroit MI and fellowship training from Indiana University, Indianapolis IN. Dr. Mamdani is involved in a large number of national and global clinical trials evaluating novel therapeutic agents for the treatment of thoracic cancers. Her areas of research interest include immunotherapy and DNA repair pathways.
Education & Training
- Indiana University School of MedicineFellowship, Hematology and Medical Oncology, 2014 - 2017
- Detroit Medical Center/Wayne State UniversityResidency, Internal Medicine, 2011 - 2014
- M.P. Shah Medical CollegeClass of 2009
Certifications & Licensure
- MI State Medical License 2016 - 2026
- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Hematology
- American Board of Internal Medicine Medical Oncology
Awards, Honors, & Recognition
- Young Investigator Award Immunooncology Young Investigators’ Forum, 2019
- Young Investigator Award Young Investigators’ Forum in Lung Cancer, 2019
Clinical Trials
- A Study of Sapanisertib in Relapsed/Refractory NFE2L2-Mutated and Wild-Type Squamous Non-Small Cell Lung Cancer Start of enrollment: 2022 Apr 15
Roles: Principal Investigator, Contact
- NT-I7 (Efineptakin Alfa) in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Start of enrollment: 2020 Jun 10
Roles: Contact
- Chiauranib for Advanced Solid Malignant Tumors and Relapsed/Refractory SCLC. Start of enrollment: 2022 Aug 26
Roles: Contact, Principal Investigator
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Publications & Presentations
PubMed
- 131 citationsImmunotherapy in Lung Cancer: Current Landscape and Future Directions.Hirva Mamdani, Sandro Matosevic, Ahmed Bilal Khalid, Gregory Durm, Shadia I Jalal
Frontiers in Immunology. 2022-01-01 - 2 citationsRacial and socioeconomic disparities in survival among patients with metastatic non-small cell lung cancer.Dipesh Uprety, Randell Seaton, Tarik Hadid, Hirva Mamdani, Ammar Sukari
Journal of the National Cancer Institute. 2024-10-01 - 14 citationsTherapy for Stage IV Non-Small-Cell Lung Cancer Without Driver Alterations: ASCO Living Guideline, Version 2023.1.Navneet Singh, Ishmael A Jaiyesimi, Nofisat Ismaila, Natasha B Leighl, Hirva Mamdani
Journal of Clinical Oncology. 2023-05-20
Lectures
- Safety and efficacy of durvalumab following multimodality therapy for locally advanced esophageal and GEJ adenocarcinoma: Two-year follow-up results from Big Ten Cance...ASCO Gastrointestinal Cancers Symposium - San Francisco, CA - 1/23/2020
- A phase II study evaluating safety and efficacy of niraparib in patients with previously treated homologous recombination (HR) defective or loss of heterozygosity (LOH...ASCO Gastrointestinal Cancers Symposium - San Francisco, CA - 1/23/2020
- Safety and efficacy of durvalumab following multimodality therapy for locally advanced esophageal and GEJ adenocarcinoma: Results from big ten cancer research consorti...ASCO Annual Meeting 2019 - Chicago, IL - 6/3/2019
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Press Mentions
- Karmanos Cancer Institute Recognizes Lung Cancer Awareness Month, Encourages ScreeningsNovember 4th, 2024
- Early Detection Is Key for This Common Form of CancerNovember 21st, 2022
- Karmanos Cancer Institute Partners with Nation's Top Cancer Organizations to Endorse Initiative to Increase Lung Cancer Screening in the United StatesNovember 1st, 2022
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Professional Memberships
- Member
- Member
- Member
Other Languages
- Hindi, Gujarati
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