HenryDClarkeMD

Orthopaedic Surgery • Phoenix, AZ

Chair, Department of Orthopedic Surgery; Professor of Orthopedics, Mayo Clinic College of Science & Medicine

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Office
5777 E Mayo Blvd
Phoenix, AZ 85054
Phone+1 480-342-2407

Fax+1 480-342-2696

Summary

Dr Henry D. Clarke completed his orthopedic surgery residency at Mayo Clinic, and a fellowship in Knee Surgery, with Dr John Insall, at the Insall Scott Kelly Institute in New York. He has lectured extensively about knee surgery, and has authored more than 100 articles and book chapters. Dr Clarke is the Deputy Editor for Hip & Knee for JAAOS. Dr Clarke also serves as the Chair of Continuing Medical Education for the American Association of Orthopedic Surgeons and Chair of the International Committee for ICJR. Dr Clarke is the Chair of Orthopedic Surgery at the Mayo Clinic in Phoenix, USA where he specializes in robotic and custom knee replacement.

Education & Training

Mayo Clinic College of Medicine and Science (Rochester)Residency, Orthopaedic Surgery, 1993 - 1998
Rutgers Robert Wood Johnson Medical SchoolClass of 1993
Princeton UniversityB.A., Economics, Cum Laude, 1985 - 1989

Certifications & Licensure

AZ State Medical License 2004 - 2026
MN State Medical License 1994 - 2025
NY State Medical License 1998 - 2025
American Board of Orthopaedic Surgery Orthopaedic Surgery

Awards, Honors, & Recognition

Chitranjan Ranawat Award for Surgical Technique Knee Society, 2014
Top Doctors:Arizona State Castle Connolly, 2013
Achievement Award American Academy of Orthopedic Surgeons, 2010
Knee Society Scholar Award Association of Bone & Joint Surgeons, 2008
John N. Insall Traveling Fellowship Knee Society, 2004
Faculty Research Award Mayo Clinic, Department of Orthopaedic Surgery, 1996
Alpha Omega Alpha Medical Honor Society UMDNJ: Robert Wood Johnson Medical School, 1993
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Clinical Trials

Regional Prophylactic Vancomycin in Revision Total Knee Replacement Start of enrollment: 2013 Dec 01
Completed
Phase 2, Phase 3

Publications & Presentations

PubMed

Multicenter Randomized Clinical Trial of Highly Cross-Linked Polyethylene Versus Conventional Polyethylene in 518 Primary TKAs at 10 Years.
Harold I Salmons, Dirk R Larson, Cedric J Ortiguera, Henry D Clarke, Mark J Spangehl
The Journal of Bone and Joint Surgery. American Volume. 2024-11-06
Risk Factors in Patients Who Had Prior Renal or Liver Transplant Undergoing Primary Total Knee Arthroplasty.
Elie Mansour, Sayi P Boddu, Vikram S Gill, Bassam G Abu Jawdeh, Alyssa K McGary
The Journal of Arthroplasty. 2024-09-01
Clostridium difficile Infection Prior to Total Hip Arthroplasty Independently Increases the Risk of Periprosthetic Joint Infection.
David G Deckey, Sayi P Boddu, Jens T Verhey, Stephen A Doxey, Mark J Spangehl
The Journal of Arthroplasty. 2024-09-01

Journal Articles

Knee Society Award Papers Are Highly Cited Works
Mroz TP, Clarke HD, Chang YH, Scuderi GR, Clinical Orthopedics and Related Research, 1/27/2015
Higher Rate of Revision in PFC Sigma Primary Total Knee Arthroplasty With Mismatch of Femoro-Tibial Component Sizes
Young SW, Clarke HD, Graves SE, Liu YL, de Steiger RN, Journal of Arthroplasty, 1/1/2015
Periarticular Injections and Femoral & Sciatic Blocks Provide Similar Pain Relief After TKA: A Randomized Clinical Trial
Spangehl MJ, Clarke HD, Hentz JG, Misra L, Blocher JL, Seamans DP. The Chitranjan Ranawat Award, Clinical Orthopedics and Related Research, 1/1/2015
Tibial component rotation: The inveterate problem
Clarke HD, Clarke HD, 1/1/2014
The Alpha Defensin-1 Biomarker Assay can be Used to Evaluate the Potentially Infected Total Joint Arthroplasty
Bingham J, Clarke H, Spangehl M, Schwartz A, Beauchamp C, Goldberg B, Clin Orthop Relat Res, 1/1/2014
Gender optimized patellar component designs are needed to better match female patellar anatomy
Clarke HD, Spangehl MJ, The Knee, 1/1/2014
Letter to the Editor
Ries M, Donell S, Clarke HD, The Knee, 1/1/2013
Voriconazole is delivered from antifungal-loaded bone cement
Miller RB; McLaren AC; Pauken C; Clarke HD; McLemore R, Clinical Orthopedics and Related Research, 1/1/2013
Effect of body mass index on limb alignment after total knee arthroplasty
Estes CS, Schmidt KJ, McLemore R, Spangehl MJ, Clarke HD, Journal of Arthroplasty, 1/1/2013
Preoperative patient education reduces in-hospital falls after total knee arthroplasty
Clarke HD, Timm VL, Goldberg BR, Hattrup SJ, Clinical Orthopedics and Related Research, 1/1/2012
Changes in Posterior Condylar offset after total knee arthroplasty can not be determined by radiographic measurements alone
Clarke HD, Journal of Arthroplasty, 1/1/2012
Analysis of Total Arthroplasty Costs in Chinese Patients
Zhang Y, Zhang H, Clarke HD, Hattrup SJ, Journal of Arthroplasty, 1/1/2012
Full disclosure is only the first step in managing potential conflicts of interest: Commentary on an article by Young-Kyun Lee, MD, et al: "Conflict of interest in the...
Clarke HD, Journal of Bone and Joint Surgery-American, 1/1/2012
Limb Alignment Improves with Computer-Assisted Navigation in Total Knee Replacement, But Questions Remain Commentary on an article by Guo-qiang Zhang, MD, et al: “Comp...
Clarke HD, Journal of Bone and Joint Surgery-American, 1/1/2011
Case Report- Five cases of failure of the tibial polyethylene insert locking mechanism in one design of constrained knee replacement
Rapuri VR, Clarke HD, Spangehl MJ, Beauchamp CP, Journal of Arthroplasty, 1/1/2011
Prophylactic flap reconstruction of the knee prior to total knee arthroplasty in high risk patients
Casey III WJ, Rebecca AM, Krochmal DJ, Kim HY, Hemminger BJ, Clarke HD, Spangehl, MJ, Smith AA, Annals of Plastic Surgery, 1/1/2011
Clinical outcomes in patients who require surgical evacuation of an acute hematoma following total knee arthroplasty
Clarke HD, European Musculoskeletal Review, 1/1/2011
A two-stage retention debridement protocol for acute periprosthetic joint infections
Estes CS, Beauchamp CP, Clarke HD, Spangehl MJ, Clinical Orthopedics and Related Research, 1/1/2010
Iron supplementation for anemia after hip fracture surgery
Clarke HD. Commentary on an article by Martyn J. Parker, MD, Journal of Bone and Joint Surgery- American, 1/1/2010
Primary total knee arthroplasty
Lombardi AV Jr. Nett MP. Scott WN. Clarke HD. Berend KR. O'Connor MI, Journal of Bone & Joint Surgery - American, 1/1/2009
Surgical Treatment of Early Wound Complications Following Primary Total Knee Arthroplasty
Galat DD, McGovern SC, Larson DR, Harrington JR, Hanssen AD, Clarke HD, Journal of Bone and Joint Surgery-American, 1/1/2009
Blood management in total knee arthroplasty
Sinclair KC, Clarke HD, Noble BN, A comparison of techniques, Orthopedics, 1/1/2009
Techniques in soft tissue coverage around the knee
Andres LA, Casey III WJ, Clarke HD, Techniques in Knee Surgery, 1/1/2009
Primary total knee arthroplasty: the impact of technique
Mahoney OM. Clarke HD. Mont MA. McGrath MS. Zywiel MG. Dennis DA. Kim RH. Carothers J, Journal of Bone & Joint Surgery - American, 1/1/2009
Venous thromboembolism debate in joint arthroplasty
Lieberman JR. Barnes CL. Lachiewicz PF. Hanssen AD. Clarke HD. Pellegrini VD Jr, Journal of Bone & Joint Surgery – American, 1/1/2009
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Books/Book Chapters

Atlas of Revision Hip and Knee Arthroplasty
Chapter: Debridement with Component Retention for Acute Periprosthetic Total Knee Infections
Estes CS, Spangehl MJ, Clarke HDEditors: Scuderi GR, Tria AJ, Kang M, Long W.Elsevier, Philadelphia, PA2015
Atlas of Revision Hip and Knee Arthroplasty
Chapter: Soft Tissue Coverage
Clarke HD, Rebecca AM, Casey WJ IIIEditors: Scuderi GR, Tria AJ, Kang M, Long W.Elsevier, Philadelphia, PA2015
Atlas of Revision Hip and Knee Arthroplasty
Chapter: Wound Management
Clarke HD, Casey WJ III, Rebecca AMEditors: Scuderi GR, Tria AJ, Kang M, Long W.Elsevier, Philadelphia, PA2015
Atlas of Revision Hip and Knee Arthroplasty
Chapter: Manipulation
Clarke HD, Spangehl MJEditors: Scuderi GR, Tria AJ, Kang M, Long W.Elsevier, Philadelphia, PA2015
Fundamentals of Revision Knee Arthroplasty: Diagnosis, Evaluation and Treatment
Chapter: Periprosthetic Fractures
Schwartz AJ, Clarke HDEditors: Jacofsky D, Hedley A.SLACK Incorporated, Thorofare, NJ2013
Selective Exposures in Orthopedic Exposures: The Knee
Clarke HD, Bush-Joseph CA, Wolf BRAmerican Academy of Orthopaedic Surgeons, Rosemont, ILEdition 2nd,2012
Revision total hip and knee arthroplasty
Chapter: Wound complications
Clarke HD, Scott SC, Scott WNEditors: Berry DJ; Trousdale RT, Dennis DA, Paprosky WG.Wolters Kluwer Health/Lippincott Williams & Wilkins, Philadelphia, PA2012
Joint Replacement Arthroplasty
Chapter: High Flexion, Gender optimized and guided motion knee prostheses; Rationale and available results
Sagherian BH, Clarke HDEditors: Morrey BF, Berry DJ.Churchill Livingstone/Elsevier, Philadelphia, PAEdition 4th,2011
Surgery of the Knee
Chapter: Revision TKA- Hinged implants
Clarke HD, Scott WN, Insall JN, Pedersen HB, Math KR, Vigorita VJ, Cushner FDEditors: Scott WN.Churchill Livingstone/Elsevier, Philadelphia, PAEdition 5th,2011
Joint Replacement Arthroplasty
Clarke HD. Valgus TKREditors: Morrey BF, Berry DJ.Churchill Livingstone/Elsevier, Philadelphia, PA2011
Advanced Reconstruction: Knee
Chapter: Revision Total Knee Arthroplasty: Hinged Implants
Clarke HDEditors: Lieberman JR, Berry DJ, Azar FM.AAOS, Rosemont, IL2011
Advanced Knee Reconstruction
Chapter: Revision TKA- Hinged implants
Clarke HDAmerican Academy of Orthopaedic Surgeons, Rosemont, IL2010
Master Techniques in Orthopaedic Surgery: Knee Arthoplasty
Chapter: Managing bone loss with metal augments
Clarke HD, Hanssen ADEditors: Lonner JH. Lotke PA.Lippincott Williams & Wilkins, Philadelphia, PAEdition 3rd,2009
Total Knee Replacement
Chapter: Monoblock total knee arthroplasty
Long WJ, Cushner FD, Clarke HDEditors: Hanssen AD, Scott, WN.Saunders Elsevier, Philadelphia, PA2009
Total Knee Replacement
Chapter: Valgus total knee replacement
Clarke HDEditors: Hanssen AD, Scott, WN.Saunders Elsevier, Philadelphia, PA2009
Master Techniques in Orthopaedic Surgery: Soft Tissue
Chapter: Revision and infected total knee arthroplasty
Clarke HD, Casey WJ III, Spangehl MJEditors: Cooney WP, Moran SL.Lippincott Williams & Wilkins, Philadelphia, PA2008
Adult Reconstruction
Chapter: Total knee arthroplasty
Clarke HDEditors: Berry DJ, Steinmann S.Lippincott Williams & Wilkins, Philadelphia, PA2007
Instructional Course Lectures: Knee
Chapter: Alternatives to Total Knee Arthroplasty: Commentary
Clarke HDEditors: Pagnano MW.American Academy of Orthopaedic Surgeons, Rosemont, IL2007
Knee Arthroplasty Handbook
Chapter: Two stage reimplantation for infection
Scuderi GR, Clarke HDEditors: Scuderi GR, Tria AJ.Springer-Verlag, New York, NY2006
OKU: Hip and Knee Reconstruction 3
Chapter: Alternatives in knee arthritis: arthroscopy and cartilage restoration
Clarke HD, Scott WNEditors: Barrack RL, Booth RE, Jr, Lonner JH, McCarthy JC, Mont MA, Rubash HE.American Academy of Orthopaedic Surgeons, Rosemont, IL2006
Surgery of the Knee
Chapter: Historic development, classification, and characteristics of knee prostheses
Insall JN, Clarke HDEditors: Scott WN.Churchill Livingstone/Elsevier, Philadelphia, PAEdition 4th,2006
Surgery of the Knee
Chapter: Clinical algorithm for treatment of chondral injuries
Clarke HD, Cushner FD, Scott WNEditors: Scott WN.Churchill Livingstone/Elsevier, Philadelphia, PAEdition 4th,2006
Surgery of the Knee
Chapter: Arthroscopic treatment of degenerative arthritis of the knee
Clarke HD, Scott WNEditors: Scott WN.Churchill Livingstone/Elsevier, Philadelphia, PAEdition 4th,2006
Surgery of the Knee
Chapter: Anatomic aberrations
Clarke HD, Scott WN, Insall JNEditors: Scott WN.Churchill Livingstone/Elsevier, Philadelphia, PA2006
Surgical Techniques for the Knee
Chapter: Total knee replacement:pearls of posterior cruciate ligament substitution
Clarke HD, Scuderi GR, Insall JNEditors: Cushner FD, Scott WN, Scuderi GR.Thieme, New York, NY2005
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Lectures

Management of Common Complications of TKA
Las Vegas, NV - 1/28/2015
Managing the Scary Knee
Las Vegas, NV - 1/28/2015
Sports Participation after TKA
Paris, France - 1/18/2015
Tibial Tuberosity Osteotomy
Paris, France - 1/18/2015
Managing the Valgus Knee
Beijing, China - 1/15/2015
Higher Rate of Revision in Primary TKA with Tibio-Femoral Size Mismatch: Analysis form a National Joint Registry
Telford, UK - 1/11/2015
Alignment: Classic Goals and New Concepts
Beijing, China - 1/8/2015
The Diagnosis of Infection
Beijing, China - 1/8/2015
Debridement for Acute Infection
Beijing, China - 1/8/2015
Peri-operative Pain Management
Beijing, China - 1/8/2015
Is there a Role for Debridement?
Beijing, China - 1/21/2014
Alignment in TKA: Does Accuracy Count if We Don’t Know the Target?
Los Angeles, CA - 1/19/2014
Soft Tissue Management in TKA
Los Angeles, CA - 1/19/2014
Higher Revision Rates with Component Size Mismatch
Charlotte, NC - 1/18/2014
The Selection of Knee Society Award Papers are Based on Merit
Charlotte, NC - 1/18/2014
Computer Assisted Surgery: Finally Ready for Prime Time
New Orleans, LA - 1/15/2014
Accurate Tibial Cutting and Rotational Axis are Important to Post-operative Results in TKA
Beijing, China - 1/12/2014
Perioperative Pain Control
Beijing, China - 1/12/2014
One Stage versus Two Stage Revision for Infection
Beijing, China - 1/12/2014
Options for Extensor Mechanism: Dealing with the Loss
Chicago, IL - 1/11/2014
Peri-articular Injections for Post-operative Pain Management in TKA
Norwich, UK - 1/9/2014
Peri-operative Patient Optimization
San Diego, CA - 1/6/2014
Why a TKA Wins over Uni: Evidence Based Medicine
San Diego, CA - 1/6/2014
Multi-Modal Pain Management
New York, NY - 1/5/2014
2013 ICJR West
International Congress for Joint Replacement, Napa, California - 6/6/2013
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