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Office
University of Virginia-Endocrine Division
415 Ray C. Hunt Drive
Charlottesville, VA 22903Phone+1 434-924-5629Fax+1 434-244-7593
Summary
- Helmy Siragy, M.D., FACP, FAHA, (pronouns: he/him) is the Harrison Distinguished Chair of Excellence in Medical Education and Professor of Medicine and Endocrinology. An international expert on subjects related to hypertension, Dr. Siragy was the first to discover that stimulation of angiotensin AT2 receptor leads to generation of nitric oxide. Siragy has authored more than 300 medical journal articles and abstracts, and numerous medical textbook chapters, including a chapter on the kidney and the renin angiotensin system in the Braunwald Atlas of Heart Diseases; a chapter on angiotensin and diabetic nephropathy in Harrison's on-line textbook of Medicine; and a chapter on the angiotensin receptor in Hypertension: A Companion to Brenner. Dr Siragy's primary research interests are in the areas of the renin-angiotensin system, cardiac ischemia and diabetic nephropathy. Dr. Siragy is a member of numerous national and international endocrine and hypertension societies. He serves as a reviewer for the National Institutes of Health and the American Heart Association, and is on the editorial boards of Nature Research Group, several journals in the areas of hypertension, endocrinology, and vascular biology. He edits the section on Antihypertensive Agents: Mechanisms of Drug Action for the journals Current Hypertension Reports and Current Hypertension Reviews.
Education & Training
- University of Virginia Medical CenterFellowship, Endocrinology, Diabetes, and Metabolism, 1984 - 1987
- University of Texas Medical Branch HospitalsResidency, Internal Medicine, 1982 - 1984
- University of Texas Health Science Center San Antonio Joe and Teresa Lozano Long School of MedicineFellowship, Endocrinology, Diabetes, and Metabolism, 1980 - 1982
- Tanta University Faculty of MedicineClass of 1976
Certifications & Licensure
- VA State Medical License 1984 - 2026
- NC State Medical License 1986 - 1999
- American Board of Internal Medicine Internal Medicine
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013
Publications & Presentations
PubMed
- Nephron specific ATP6AP2 knockout increases urinary excretion of fatty acids and decreases renal cortical megalin expression.Silas A Culver, Stefan R Hargett, Jamie L L Q Balugo, John J Gildea, Thurl E Harris
Scientific Reports. 2024-08-12 - Renal Hypokalemia: An Endocrine Perspective.Silas A Culver, Nawar Suleman, Varun Kavuru, Helmy M Siragy
The Journal of Clinical Endocrinology and Metabolism. 2024-06-17 - Basal cortisol levels do not predict adrenal responsiveness in acute decompensated cirrhosis.Brian J Wentworth, Matthew Schliep, Wendy M Novicoff, Zachary H Henry, Helmy M Siragy
European Journal of Gastroenterology & Hepatology. 2024-02-01
Press Mentions
- Former Dean, Failed Retiree, Redefines High Blood Pressure, Impacting MillionsMarch 8th, 2018
Grant Support
- (Pro)Renin Receptor And Renovascular HypertensionNational Institute Of Diabetes And Digestive And Kidney Diseases2012
- Prorenin Receptors Mediate Hypertension And Kidney Disease In DiabetesNational Heart, Lung, And Blood Institute2008–2012
- Renin Receptor Provoked Renal InflammationNational Institute Of Diabetes And Digestive And Kidney Diseases2007–2011
- Angiotensin II Mediates Early Changes In Diabetic KidneyNational Institute Of Diabetes And Digestive And Kidney Diseases2003–2007
- AT2 Receptor Modulates Renal Angiotensin II LevelsNational Heart, Lung, And Blood Institute2002–2005
- Inhibition Of Cytochrome P450 On Therapy Effects Of Angiotensin Recept BlockerNational Center For Research Resources1999–2002
- Study Of Valsartan In Patients W/ HypertensionNational Center For Research Resources1999–2000
- OPC 41061 In Patients W/ HyponatremiaNational Center For Research Resources1999–2000
- NO And Eicosanoid Mediate Renal Effects Of AT2 ReceptorsNational Heart, Lung, And Blood Institute1997–2000
- Rhythmic And Pulsatile Release Of AldosteroneNational Center For Research Resources1990–2000
- Paracrine Mechanisms Of Renal KininsNational Heart, Lung, And Blood Institute1994–1998
- Renal Effects Of Kinins Mediated By EDRF And EicosanoidsNational Heart, Lung, And Blood Institute1992–1997
Professional Memberships
- Member
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