HauDLeMD

PubMed

• Prophylactic surgical drain placement with irrigation reduces abscess formation in patients with severe, uncontained, perforated appendicitis.
  Michael A Stellon, Devashish S Joshi, Russell Herberg, Brittany Walker, Jessica Hellner
  Pediatric Surgery International. 2024-11-28
• Modeling high-risk Wilms tumors enables the discovery of therapeutic vulnerability.
  Gui Ma, Ang Gao, Jiani Chen, Peng Liu, Rakesh Sarda
  Cell Reports. Medicine. 2024-10-15
• Roles of pediatric surgeons in palliative pediatric oncology.
  Hau D Le, Sarah Braungart, Jaime Shalkow-Klincovstein, Nelson Piché
  Pediatric Blood & Cancer. 2024-10-04

Journal Articles

• Docosahexaenoic acid, G protein-coupled receptors, and melanoma: is G-protein-coupled receptor 40 a potential therapeutic target?  
  Nehra D, Pan AH, Le HD, Fallon EM, Carlson SJ, Kalish BT, Puder M, J Surg Res, 1/1/2014
• A Combined Richter’s and De Garengeot’s Hernia  
  Le HD, Odom SR, Hsu A, Gupta A, Hauser CJ, Inter J of Surg Case Report, 1/1/2014
• Epoxy-eicosanoids Promote Tissue and Organ Regeneration  
  Panigrahy D, Kalish B, Huang S, Bielenberg DR, Le HD,Yang J, Edin ML, Lee CR, Benny O, Mudge DK, Butterfield CE, Mammoto A, Mammoto T, Inceoglu B, Lih FB, Tomer KB, In..., Proc Natl Acad Sci, 1/1/2013
• A metabolomics analysis of two intravenous emulsion in a murine model  
  Kalish BT, Le HD, Gura KM, Bistrian BR, Puder M, PLoS One, 1/1/2013
• Intravenous fish oil lipid emulsion promotes a shift toward anti-inflammatory proresolving lipid mediators  
  Kalish BT, Le HD, Fitzgerald JM, Wang S, Seamon K, Gura KM, Gronert K, Puder M, Am J Physiol Gastrointest Liver Physiol, 1/1/2013
• Prolonging the Female Reproductive Lifespan and Improving Egg Quality with Dieaty Omega-3 Fatty Acids  
  Nehra D, Le HD, Fallon EM, Carlson SJ, Woods D, Brown YA, Pan AH, Guo L, Rodig SJ, Tilly JL, Rueda BR, Puder M, Aging Cell, 1/1/2012
• Combination of highly enriched omega-3 fatty acid diet and Sunitinib for the treatment of a murine orthotopic model of human neuroblastoma  
  Barnes CM, Prox D, Christison-Lagay EA, Le HD, Short S, Cassiola F, Panigrahy D, Chaponis D, Butterfield C, Kieran M, Fishman S, Folkman J, Puder M, Pediatr Res, 1/1/2012
• The Effects of Varying Ratios of Docosahexaenoic Acid and Arachidonic Acid Ratios in the Prevention and Reversal of Biochemical Essential Fatty Acid Deficiency in a Mu...  
  Le HD, Fallon EM, Kalish B, de Meijer VE, Meisel JA, Gura KM, Nose V, Bistrian BR, Puder M, Metabolism, 1/1/2012
• Docosahexaenoic acid and arachidonic acid prevent essential fatty acid deficiency and hepatic steatosis  
  Le HD, Meisel JA, de Meijer VE, Fallon EM, Gura KM, Nose V, Bistrian BR, Puder M, J Parenter Enteral Nutr, 1/1/2012
• Dietary Fish Oil Aggravates Paracetamol-Induced Liver Injury in Mice  
  de Meijer VE, Kalish BT, Meisel JA, Le HD, Puder M, J Parenter Enteral Nutr, 1/1/2012
• The Effect of Sunitinib on Functional Reproductive Outcome in a Rabbit Model  
  Fallon EM, Nehra D, Le HD, Nedder AP, Guo L, Mitchell PD, Rueda BR, Puder M, Fertility and Sterility, 1/1/2012
• Tumor necrosis factor alpha-converting enzyme inhibition reverses steatosis and insulin resistance and improved surgical outcome in mice  
  de Meijer VE, Le HD, Meisel JA, Sharma AK, Popov, Puder M, PloS ONE, 1/1/2011
• Parenteral fish-oil-based lipid emulsion improves fatty acid profiles and lipids in parenteral nutrition-depedent children  
  Le HD, de Meijer VE, Robinson EM, Zurakowski D, Potemkin AK, Arsenault DA, Falon EM, Malkan A, Bistrian BR, Gura KM, Puder M, Am J Clin Nutr, 1/1/2011
• Effects of Matrix Metalloproteinase Inhibition in a Murine Model of Renal Ischemia Reperfusion Injury  
  Novak KB, Le HD, Christison-Lagay ER, Nose V, Doiron RJ, Moses M, Puder M, Ped Res, 1/1/2010
• Dietary fat intake promotes the development of hepatic steatosis independent from excess caloric consumption in a murine model  
  de Meijer VE, Le HD, Meisel JA, Sharif MRA, Nose V, Puder M, Metabolism, 1/1/2010
• Comparison of 5 intravenous lipid emulsions and their effects on heptic steatosis in a murine model  
  Meisel JA, Le HD, de Meijer VE, Nose V, Gura KM, Mulkern RV, Sharif MR, Puder M, J Pediatr Surg, 1/1/2010
• Parenteral fish oil as monotherapy prevents essential fatty acid deficiency in parenteral nutrition dependent patients  
  de Meijer VE, Le HD, Meisel JA, Gura KM, Puder M, J Pediatr Gastroenterol Nutr, 1/1/2010
• Parenteral Fish Oil as Monotherapy Improves Lipid Profiles in Patients With Parenteral Nutrition-Associated Cholestasis  
  Le HD, de Meijer VE, Meisel JA, Gura KM, Puder M. Le HD, de Meijer VE, Meisel JA, Puder M, J Parenter Enteral Nutr, 1/1/2010
• Prevention of parenteral nutrition-associated liver disease: the role of omega-3 fish oil  
  Fallon EM, Le HD, Puder M, Curr Opin Organ Transplant, 1/1/2010
• Fish oil-based lipid emulsions prevent and reverse parenteral nutrition-associated liver disease: the Boston experience  
  de Meijer VE, Gura KM, Le HD, Meisel JA, Puder M, J Parenter Enteral Nutr, 1/1/2009
• The Impact of Fish Oil-Based Lipid Emulsion on Serum Triglyceride, Bilirubin, and Albumin Levels in Children with Parenteral Nutrition-Associated Liver Disease  
  Lee SI, Valim C, Johnston P, Le HD, Meisel J, Arsenault DA, Gura KM, Puder M, Pediatr Res, 1/1/2009
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Books/Book Chapters

• Nutrition, Diet Therapy, and the Liver 
  Chapter: Using Parenteral Fish Oil in NASH 
  Page 81 - 90Meisel JA, Le HD, de Meijer VE, Gura KM, Puder MEditors: Preedy VR, Lakshman R, Srirajaskanthan R, Watson RR.CRC Press, Boca Raton, FL2010

Abstracts/Posters

• Diffuse Pulmonary Lymphagiomatosis With Extensive Mediastinal Involvement – A Case Report.
  Le HD, Brahmamdam P, Manson DE, Connely B, Amaral J, Taylor G, Chiu P, Canadian Association of Peadiatric Surgery, Montreal, Quebec, Canada, 1/1/2014
• A Diet of Docosahexaenoic Acid and Arachidonic Acid Maintains Normal Growth and Reproductive Function over Multiple Generations in a Mouse Model.
  Nehra D, Le HD, Fallon EM, Carlson S, Pan A, Rodig S, Puder M, American Society of Parenteral and Enteral Nutrition (ASPEN) – Clinical Nutrition Week, Orlando, FL, 1/1/2012
• A Combined Richter’s and De Garengeot’s Hernias: Case Report and Review of the Modern Literature.
  Le HD, Odom SR, Hsu A, Gupta A, Hauser CJ, Hernia Congress, New York, NY, 1/1/2012
• Omega-3 Fatty Acids Inhibit the Growth of Neuroblastoma Tumor and Induce a Tumor Specific Essential Fatty Acid Deficiency in a Murine Xenograft Tumor Model.
  Nehra D, Fallon EM, Le HD, de Meijer VE, Pan AH, Mitchell P, Puder M, American Pediatric Surgical Association 42nd Annual Meeting, Palm Desert, CA, 1/1/2011
• The Efficacy and Safety of Sunitinib in the Prevention of Pelvic Adhesion Formation in a Rabbit Model.
  Fallon EM, Nehra D, Potemkin AK, Le HD, Brown DW, Nedder AP, Puder M, New England Surgical Society Resident and Fellow Research Presentation Day, Boston, MA, 1/1/2011
• Omega-3 Fatty Acids Inhibit the Growth of Neuroblastoma Tumor and Induce a Tumor Specific Essential Fatty Acid Deficiency in a Murine Xenograft Tumor Model.
  Nehra D, Fallon EM, Le HD, de Meijer VE, Pan AH, Mitchell P, Puder M, New England Surgical Society Research Day, Boston, MA, 1/1/2011
• Effect of Anti-Angiogenic Therapy on Adhesion Formation and Functional Outcome in a Leporine Model.
  Fallon EM, Le HD, de Meijer VE, Puder M, American College of Surgeons, Annual Meeting, Washington, DC, 1/1/2010
• Endothelial-derived epoxyeicosatrienoic acids promote compensatory lung growth after unilateral pneumonectomy in transgenic mice.
  Le HD, Zeldin DC, Kieran MW, de Meijer VE, Edin ME, Lee CR, Vergilio J, Hammock BD, Puder M, Panigrahy D, American Pediatric Surgical Association 41st Annual Meeting, Orlando, FL, 1/1/2010
• Parenteral Fish Oil-Based Lipid Emulsion Improved Lipid and Fatty Acid Profiles in Parenteral Nutrition-Dependent Patients.
  Le HD, de Meijer VE, Robinson EM, Arsenault DA, Potemkin AK, Zurakowski D, Malkan A, Fallon E, Gura KM, Puder M, American Society of Parenteral and Enteral Nutrition (ASPEN) – Clinical Nutrition Week, Las Vegas, NV, 1/1/2010
• Endothelial-derived epoxyeicosatrienoic acids promote organ regeneration.
  Le HD, Kieran MW, Zeldin DC, Kalish B, de Meijer ME, Edin ML, Lee CR, Vergilio J, Hammock BD, Puder M, Panigrahy M, Dr. M. Judah Folkman Research Day, Boston, MA, 1/1/2010
• Endothelial-derived epoxyeicosatrienoic acids promote organ regeneration.
  Le HD, Kieran MW, Zeldin DC, Kalish B, de Meijer ME, Edin ML, Lee CR, Vergilio J, Hammock BD, Puder M, Panigrahy M, New England Surgery Society Research Day, Boston, MA, 1/1/2010
• The Effect of Sunitinib Therapy on Adhesion Formation and Functional Outcome in a Leporine Model.
  Fallon EM, Nehra D, Le HD, Meisel JA, de Meijer VE, Puder M, Massachusetts Chapter of the American College of Surgeons, Annual Meeting, Boston, MA, 1/1/2010
• Biomemetic Spleen for Clinical Therapeutic and Diagnostic Applications.
  Yung CW, Cooper RM, Le HD, de Meijer VE, Tsai S, Stone H, Puder M, Ingber ED, Wyss Institute Retreat, 1/1/2009
• Inhibition of Intra-abdominal Adhesion Formation in a Rabbit Model with the Angiogenesis Inhibitor Sunitinib.
  Meisel JA, Le HD, de Meijer VE, Puder M, 40th Annual Meeting of the American Pediatric Surgical Association, Fajardo, Puerto Rico, 1/1/2009
• Docosahexaenoic acid and Arachidonic Acid Prevent Essential Fatty Acid Deficiency and Hepatic Steatosis.
  Le HD, Meisel JA, de Meijer VE, Gura KM, Nose V, Bistrian BR, Puder M, 40th Annual Meeting of the American Pediatric Surgical Association, Fajardo, Puerto Rico, 1/1/2009
• Parenteral Fish Oil as Monotherapy Prevents Essential Fatty Acid Deficiency in Parenteral Nutrition Dependent Patients.
  de Meijer VE, Le HD, Meisel JA, Gura KM, Puder M, 40th Annual Meeting of the American Pediatric Surgical Association, Fajardo, Puerto Rico, 1/1/2009
• Biomimetic Spleen (BioSpleen) for Sepsis Therapy.
  Cooper RM, Yung CW, Le HD, de Meijer VE, Puder M, Ingber DE, CIMIT Congress, Boston, MA, 1/1/2009
• Parenteral Fish Oil as Monotherapy Improves Lipid Profiles in Patients With Parenteral Nutrition-Associated Liver Disease.
  Le HD, de Meijer VE, Meisel JA, Puder M, 60th Annual Meeting of the American Association for the Study of Liver Diseases, Boston, MA, 1/1/2009
• Broad-Spectrum Matrix Metalloproteinase Inhibition Curbs Inflammation but Aggravates Fibrosis in a Murine Model of chronic carbon tetrachloride induced injury.
  de Meijer VE, Sverdlov DY, Popov Y, Meisel JA, Le HD, Nose V, Schuppan D, Puder M, 60th Annual Meeting of the American Association for the Study of Liver Diseases, Boston, MA, 1/1/2009
• Dietary omega-3 fatty acid supplementation aggravates hepatic injury and fibrosis in acute and chronic carbon tetrachloride administration in mice.
  de Meijer VE, Popov Y, Sverdlov DY, Le HD, Meisel JA, Schuppan D, Puder M, 60th Annual Meeting of the American Association for the Study of Liver Diseases, Boston, MA, 1/1/2009
• Broad-spectrum matrix metalloproteinase inhibition reverses hepatic steatosis and insulin resistance in murine models of diet-induced obesity and leptin deficiency.
  de Meijer VE, Le HD, Meisel JA, Puder M, 60th Annual Meeting of the American Association for the Study of Liver Diseases, Boston, MA, 1/1/2009
• Towards An Ideal Lipid Emulsion Using Only The True Essential Fatty Acids Docosahexaenoic Acid and Arachidonic Acid.
  Le HD, De Meijer VE, Meisel JA, Gura KM, Nose V, Puder M, Dr. M. Judah Folkman Research Day, Boston, MA, 1/1/2009
• Parenteral Fish Oil as The Sole Source of Fat Prevents Essential Fatty Acid Deficiency in Parenteral Nutrition Dependent Patients.
  de Meijer VE, Le HD, Meisel JA, Gura KM, Puder M, Dr. M. Judah Folkman Research Day, Boston, MA, 1/1/2009
• Micromagnetic-Microfluidic Blood Cleansing System for Sepsis Therapy.
  Yung C, Meisel J, Le HD, de Meijer VE, Fiering J, Puder M, Borenstein J, Ingber D, CIMIT Innovation Congress, Boston, MA, 1/1/2008
• Dietary Fat Intake Promotes the Development of Hepatic Steatosis in Absence of Excess Caloric Consumption.
  de Meijer VE, Le HD, Meisel J, Puder M, 4th Metabolic Diseases World Summit, Boston, MA, 1/1/2008
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Lectures

• Role of pediatric surgeons in pediatric oncology. 
  Rockford, IL - 1/20/2015
• Diffuse Pulmonary Lymphagiomatosis With Extensive Mediastinal Involvement – A Case Report. 
  Montreal, Quebec, Canada - 1/1/2014
• Repair of Paraeasophageal Hernia. 
  Beth Israel Deaconess Medical Center, Boston, MA - 1/1/2013
• Epoxy-eicosanoids Promote Tissue and Organ Regeneration. 
  Beth Israel Deaconess Medical Center, Boston, MA - 1/1/2012
• Surgical Boot Camp 
  Beth Israel Deaconess Medical Center, Harvard Medical School - 1/1/2012
• Chief Resident in Education 
  Beth Israel Deaconess Medical Center, Harvard Medical School - 1/1/2012
• Principle Clinical Experience 
  Harvard Medical School - 1/1/2012
• Endothelial-derived epoxyeicosatrienoic acids promote organ regeneration 
  Boston, MA - 1/1/2010
• Not All Fats Are Created Equal. 
  Children’s Hospital Boston, Boston, MA - 1/1/2010
• Endothelial-derived epoxyeicosatrienoic acids promote organ regeneration. 
  Children’s Hospital Boston, Boston, MA - 1/1/2010
• Essential Fatty Acids and Their Role in Organ Regeneration and Cancer. 
  Children’s Hospital Boston, Boston, MA - 1/1/2010
• Parenteral Fish Oil-Based Lipid Emulsion Improved Lipid and Fatty Acid Profiles in Parenteral Nutrition-Dependent Patients. 
  Las Vegas, NV - 1/1/2010
• Endothelial-derived epoxyeicosatrienoic acids promote compensatory lung growth after unilateral pneumonectomy in transgenic mice. 
  Orlando, FL - 1/1/2010
• Understanding Parenteral Nutrition-Associated Liver Disease and Redefining Essential Fatty Acids. 
  Children’s Hospital Boston, Boston, MA - 1/1/2009
• Docosahexaenoic acid and Arachidonic Acid Prevent Essential Fatty Acid Deficiency and Hepatic Steatosis. 
  Fajardo, Puerto Rico - 1/1/2009
• Introduction to Vertebrate Surgery 
  Harvard Medical School - 1/1/2009
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