Harold A. Chapman MD
Infectious Disease, Pleural Disease
Professor, Medicine, UCSF School of Medicine
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505 Parnassus AveSan Francisco, CA 94143
Phone+1 415-443-4283
Fax+1 415-476-4150
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Education & Training
University of Utah HealthFellowship, Infectious Disease, 1975 - 1978- University of Utah HealthResidency, Internal Medicine, 1972 - 1975
University of Alabama School of MedicineClass of 1972
Certifications & Licensure
CA State Medical License 2000 - 2026
American Board of Internal Medicine Internal Medicine- American Board of Internal Medicine Pulmonary Disease
Awards, Honors, & Recognition
- Elected Member The American Society for Clinical Investigation, 1987
- Super Doctor SuperDoctors.com
Clinical Trials
- Study of Oral Epigallocatechin-3-gallate (EGCG) in IPF Patients Start of enrollment: 2023 Aug 24
Roles: Principal Investigator, Contact
- Collagen-targeted Positron Emission Tomography (PET) Imaging for Assessment of EGCG Effect Start of enrollment: 2024 Feb 07
Roles: Contact
Publications & Presentations
PubMed
- 7 citationsA fibroblast-dependent TGF-β1/sFRP2 noncanonical Wnt signaling axis promotes epithelial metaplasia in idiopathic pulmonary fibrosis.Max L Cohen, Alexis N Brumwell, Tsung Che Ho, Kiana Garakani, Genevieve Montas
The Journal of Clinical Investigation. 2024-07-09 - 2 citationsBCL-2 Modulates IRE1α Activation to Attenuate Endoplasmic Reticulum Stress and Pulmonary Fibrosis.Claude Jourdan Le Saux, Tsung Che Ho, Alexis M Brumwell, Jaymin J Kathiriya, Ying Wei
American Journal of Respiratory Cell and Molecular Biology. 2024-04-01 - A fibroblast-dependent TGFβ1/sFRP2 noncanonical Wnt signaling axis underlies epithelial metaplasia in idiopathic pulmonary fibrosis.Max L Cohen, Alexis N Brumwell, Tsung Che Ho, Genevieve Montas, Jeffrey A Golden
Biorxiv. 2023-08-04
Press Mentions
Could Green Tea Extract Help Fight Pulmonary Fibrosis?April 13th, 2020
Startup Science: How the Idea for Synthetic Cells Took Silicon Valley by StormJune 12th, 2018
New Compounds May Inhibit Driver of Collagen Deposits in PF, Study ShowsOctober 9th, 2017
Grant Support
- Program to promote lung regeneration and block fibrosisUNIVERSITY OF CALIFORNIA, SAN FRANCISCO2020–2027
- Phase 1 study of oral epigallocatechin-3-gallate (EGCG) in IPF patientsUNIV OF MASSACHUSETTS MED SCH WORCESTER2024–2026
- Phase 1 study of oral epigallocatechin-3-gallate (EGCG) in IPF patientsUNIV OF MASSACHUSETTS MED SCH WORCESTER2024–2026
- Phase 1 study of oral epigallocatechin-3-gallate (EGCG) in IPF patientsUNIV OF MASSACHUSETTS MED SCH WORCESTER2024–2026
- Phase 1 study of oral epigallocatechin-3-gallate (EGCG) in IPF patientsUNIV OF MASSACHUSETTS MED SCH WORCESTER2024–2026
- Phase 1 study of oral epigallocatechin-3-gallate (EGCG) in IPF patientsUNIV OF MASSACHUSETTS MED SCH WORCESTER2024–2026
- Phase 1 study of oral epigallocatechin-3-gallate (EGCG) in IPF patientsUNIV OF MASSACHUSETTS MED SCH WORCESTER2024–2026
- Epithelial stem/progenitor cells as repair agents in diffuse alveolar damageUNIVERSITY OF CALIFORNIA, SAN FRANCISCO2016–2025
- Epithelial Progenitor Cells In Lung Repair And RegenerationNational Heart, Lung, And Blood Institute2012
- Epithelial Mesenchymal Transition In Pulmonary FibrosisNational Heart, Lung, And Blood Institute2010–2012
- Urokinase Receptor Integrin Interactions In Lung CancerNational Cancer Institute2007–2011
- Role Of Elastolytic Cathepsins In EmphysemaNational Heart, Lung, And Blood Institute2001–2010
- Identification, Isolation, And Reprogramming Alveolar Epithelial Progenitor CellsNational Heart, Lung, And Blood Institute2009
- Regulation Of Integrin FunctionNational Heart, Lung, And Blood Institute2000–2009
- Cysteine Proteases In MHC Class II Antigen PresentationNational Heart, Lung, And Blood Institute2000–2007
- Cysteine Proteases In MHC Class II Antigen PresentationNational Heart, Lung, And Blood Institute1998–1999
- Alveolar Macrophage Serine Proteinases In Lung BiologyNational Heart, Lung, And Blood Institute1991–1999
- Cathepsin S And Alzheimers DiseaseNational Institute On Aging1995–1997
- Human Alveolar Macrophage Elastases In EmphysemaNational Heart, Lung, And Blood Institute1993–1997
- Role Of Human Alveolar Macrophages In EmphysemaNational Heart, Lung, And Blood Institute1985–1987
- Interaction Of Human Alveolar Macrophages Wih FibrinNational Heart, Lung, And Blood Institute1985–1987
- Role Of Human Alveolar Macrophages In EmphysemaNational Heart, Lung, And Blood Institute1985
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