HaroldA.ChapmanMD

Pulmonology • San Francisco, CA

Infectious Disease, Pleural Disease

Professor, Medicine, UCSF School of Medicine

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Office
505 Parnassus Ave
San Francisco, CA 94143
Phone+1 415-443-4283

Fax+1 415-476-4150

Education & Training

University of Utah HealthFellowship, Infectious Disease, 1975 - 1978
University of Utah HealthResidency, Internal Medicine, 1972 - 1975
University of Alabama School of MedicineClass of 1972

Certifications & Licensure

CA State Medical License 2000 - 2026
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Pulmonary Disease

Awards, Honors, & Recognition

Elected Member The American Society for Clinical Investigation, 1987
Super Doctor SuperDoctors.com

Clinical Trials

Study of Oral Epigallocatechin-3-gallate (EGCG) in IPF Patients Start of enrollment: 2023 Aug 24
RECRUITING
PHASE1
Roles: Principal Investigator, Contact
Collagen-targeted Positron Emission Tomography (PET) Imaging for Assessment of EGCG Effect Start of enrollment: 2024 Feb 07
RECRUITING
PHASE1
Roles: Contact

Publications & Presentations

PubMed

7 citations
A fibroblast-dependent TGF-β1/sFRP2 noncanonical Wnt signaling axis promotes epithelial metaplasia in idiopathic pulmonary fibrosis.
Max L Cohen, Alexis N Brumwell, Tsung Che Ho, Kiana Garakani, Genevieve Montas
The Journal of Clinical Investigation. 2024-07-09
2 citations
BCL-2 Modulates IRE1α Activation to Attenuate Endoplasmic Reticulum Stress and Pulmonary Fibrosis.
Claude Jourdan Le Saux, Tsung Che Ho, Alexis M Brumwell, Jaymin J Kathiriya, Ying Wei
American Journal of Respiratory Cell and Molecular Biology. 2024-04-01
A fibroblast-dependent TGFβ1/sFRP2 noncanonical Wnt signaling axis underlies epithelial metaplasia in idiopathic pulmonary fibrosis.
Max L Cohen, Alexis N Brumwell, Tsung Che Ho, Genevieve Montas, Jeffrey A Golden
Biorxiv. 2023-08-04

Press Mentions

Could Green Tea Extract Help Fight Pulmonary Fibrosis?April 13th, 2020
Startup Science: How the Idea for Synthetic Cells Took Silicon Valley by StormJune 12th, 2018
New Compounds May Inhibit Driver of Collagen Deposits in PF, Study ShowsOctober 9th, 2017

Grant Support

Program to promote lung regeneration and block fibrosisUNIVERSITY OF CALIFORNIA, SAN FRANCISCO2020–2027
Phase 1 study of oral epigallocatechin-3-gallate (EGCG) in IPF patientsUNIV OF MASSACHUSETTS MED SCH WORCESTER2024–2026
Phase 1 study of oral epigallocatechin-3-gallate (EGCG) in IPF patientsUNIV OF MASSACHUSETTS MED SCH WORCESTER2024–2026
Phase 1 study of oral epigallocatechin-3-gallate (EGCG) in IPF patientsUNIV OF MASSACHUSETTS MED SCH WORCESTER2024–2026
Phase 1 study of oral epigallocatechin-3-gallate (EGCG) in IPF patientsUNIV OF MASSACHUSETTS MED SCH WORCESTER2024–2026
Phase 1 study of oral epigallocatechin-3-gallate (EGCG) in IPF patientsWEILL MEDICAL COLL OF CORNELL UNIV2022–2026
Phase 1 study of oral epigallocatechin-3-gallate (EGCG) in IPF patientsWEILL MEDICAL COLL OF CORNELL UNIV2022–2026
Epithelial stem/progenitor cells as repair agents in diffuse alveolar damageUNIVERSITY OF CALIFORNIA, SAN FRANCISCO2016–2025
Epithelial Progenitor Cells In Lung Repair And RegenerationNational Heart, Lung, And Blood Institute2012
Epithelial Mesenchymal Transition In Pulmonary FibrosisNational Heart, Lung, And Blood Institute2010–2012
Urokinase Receptor Integrin Interactions In Lung CancerNational Cancer Institute2007–2011
Role Of Elastolytic Cathepsins In EmphysemaNational Heart, Lung, And Blood Institute2001–2010
Identification, Isolation, And Reprogramming Alveolar Epithelial Progenitor CellsNational Heart, Lung, And Blood Institute2009
Regulation Of Integrin FunctionNational Heart, Lung, And Blood Institute2000–2009
Cysteine Proteases In MHC Class II Antigen PresentationNational Heart, Lung, And Blood Institute2000–2007
Cysteine Proteases In MHC Class II Antigen PresentationNational Heart, Lung, And Blood Institute1998–1999
Alveolar Macrophage Serine Proteinases In Lung BiologyNational Heart, Lung, And Blood Institute1991–1999
Cathepsin S And Alzheimers DiseaseNational Institute On Aging1995–1997
Human Alveolar Macrophage Elastases In EmphysemaNational Heart, Lung, And Blood Institute1993–1997
Role Of Human Alveolar Macrophages In EmphysemaNational Heart, Lung, And Blood Institute1985–1987
Interaction Of Human Alveolar Macrophages Wih FibrinNational Heart, Lung, And Blood Institute1985–1987
Role Of Human Alveolar Macrophages In EmphysemaNational Heart, Lung, And Blood Institute1985