Gregory J Gores MD

PubMed

• Deep learning analysis of magnetic resonance imaging accurately detects early-stage perihilar cholangiocarcinoma in patients with primary sclerosing cholangitis.
  Yashbir Singh, John E Eaton, Sudhakar K Venkatesh, Christopher L Welle, Byron Smith
  Hepatology. 2025-03-20
• The dynamic landscape of cholestatic liver disease.
  Gregory J Gores, Harmeet Malhi
  Hepatology. 2025-03-07
• Aptamer-directed, nanovesicle-mediated targeting of undruggable molecules in preclinical cholangiocarcinoma models.
  Mincheng Yu, Jack W Sample, Irene K Yan, Shohei Takaichi, Jennifer L Tomlinson
  Hepatology. 2025-02-10

Journal Articles

• Intrahepatic Cholangiocarcinoma: Continuing Challenges and Translational Advances  
  Mario Strazzabosco, Florin M Selaru, Gregory J Gores, Xin Wei Wang, Hepatology
• Biliary repair and carcinogenesis are mediated by IL-33-dependent cholangiocyte proliferation  
  Li J, Razumilava N, Gores GJ, Walters S, Mizuochi T, Mourya R, Bessho K, Wang YH, Glaser SS, Shivakumar P, Bezerra JA, J Clin Invest, 1/1/2014
• Hepatocellular carcinoma: Clinical frontiers and perspectives  
  Bruix J, Gores GJ, Mazzaferro V, Gut, 1/1/2014
• Gall bladder polyps in primary sclerosing cholangitis: Adhere to the guidelines  
  Gores G , Lindor KD, Razumilava N, Hepatology, 1/1/2012
• Reply  
  Breuhahn K, Gores G , Schirmacher P, Hepatology, 8/1/2011
• A klotho beta variant mediates protein stability and associates with colon transit in irritable bowel syndrome with diarrhea  
  Wong BS, Camilleri M, Carlson PJ, Guicciardi ME, Burton D, McKinzie S, Rao AS, Zinsmeister AR, Gores GJ, Gastroenterology, 1/1/2011
• Practical management of hepatocellular carcinoma  
  Gores GJ, Gut and Liver, 1/1/2011
• Liver transplantation for non-hepatocellular carcinoma malignancies  
  Gores GJ, Heimbach JK, Rosen CB, Liver Transpl, 10/1/2010
• Reply: Diagnostic Utility of Chromosome 17 and p16 Abnormalities in Fluorescence In Situ Hybridization Tests in Primary Sclerosing Cholangitis  
  Bangarulingam SY, Bjornsson E, Enders F, Fritcher EG, Gores G , Halling KC, Lindor KD, Hepatology, 5/1/2010
• Obatoclax triggers bax mediated apoptosis in cholangiocarcinoma cells  
  Smoot R, Blechacz B, Bronk S, Werneburg N, Sirica A, Gores G, J Surg Res, 2/1/2010
• Current Opinion in Gastroenterology: Editorial introductions  
  Rockey D, Gores GJ, Curr Opin Gastroenterol, 1/1/2010
• Report of the Multisociety Task Force on GI Training  
  Friedman LS, Gores GJ, Vargo JJ, Brandt LJ, Katz PO, Stolar MH, Elta GH, Kuemmerle JF, Fitz JG, Pardi DS, Am J Gastroenterol, 11/1/2009
• Re: design and endpoints of clinical trials in hepatocellular carcinoma  
  Llovet JM, Gores GJ, J Natl Cancer Inst, 11/1/2008
• Editorial introductions  
  Pratt DS, Gores GJ, Curr Opin Gastroenterol, 1/1/2008
• Current status of liver transplantation for hilar cholangiocarcinoma  
  Rosen CB, Heimbach JK, Gores GJ, Current Opinion in Organ Transplantation, 6/1/2007
• Pathogenesis of liver injury  
  Gores GJ, Semin Liver Dis, 1/1/2007
• Death by association: BH3 domain-only proteins and liver injury  
  Baskin-Bey ES, Gores GJ, Am J Physiol Gastrointest Liver Physiol, 12/1/2005
• Prognostic analysis for survival in adult solid organ transplant recipients with post-transplantation lymphoproliferative disorders  
  Ghobrial IM, Habermann TM, Maurer MJ, Geyer SM, Ristow KM, Larson TS, Walker RC, Ansell SM, Macon WR, Gores GG , Stegall MD, McGregor CG, J Clin Oncol, 10/1/2005
• Idiopathic benign biliary strictures in surgically resected patients with presumed cholangiocarcinoma  
  Baskin-Bey ES, Devarbhavi HC, Nagorney DM, Farnell MB, Donohue JH, Sanderson SO, Stadheim LM, Gores GJ, HPB, 1/1/2005
• The death receptor TRAIL in cancer cell apoptosis  
  Ishimura N, Gores GJ, Ann. Cancer Res Ther, 1/1/2005
• Cholangiocarcinoma: Pathogenesis, diagnosis, and management - Foreword  
  Gores GJ, Semin Liver Dis, 5/1/2004
• Differential gene expression patterns in HCV-infected allografts during acute cellular rejection  
  Sreekumar R, Wiessner RH, Gores GJ, Rosen CB, Charlton MR, Liver Transpl, 1/1/2003
• The role of cell-based bioartificial liver therapy in the treatment of fulminant hepatic failure  
  Nyberg SL, Matsushita T, Gores GJ, Hay JE, Wiesner RH, Pineda AA, Gastineau DA, Moore SB, Plevak DJ, Wijdicks EF, Piepgras DG, Platt JL, Rosen CB, Graft, 10/1/2002
• Cholangiocarcinoma  
  Torok N, Gores GJ, Semin Gastrointest, 4/1/2001
• Seminars in liver disease: foreword  
  Lindor KD, Gores GJ, Semin Liver Dis, 1/1/2001
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Books/Book Chapters

• Shackelford's surgery of the alimentary tract. 
  Chapter: Primary sclerosing cholangitis. 
  Page 1405 - 1416Lazaridis KN, Gores GJEditors: Yeo CJ.Saunders Elsevier, Philadelphia, PAEdition 7th,2013
• Zakim and Boyer's hepatology: a textbook of liver disease. 
  Chapter: Cholangiocarcinoma. 
  Page 1032 - 1044Lazaridis KN, Gores GJEditors: Boyer TD; Manns MP; Sanyal AJ.Saunders Elsevier, Philadelphia, PAEdition 6th,2012
• Textbook of clinical gastroenterology and hepatology. 
  Chapter: Cholangiocarcinoma. 
  Page 580 - 585Lazaridis KN, Gores GJEditors: Hawkey CJ; et al.Wiley-Blackwell, Chichester; MaldenEdition 2nd,2012
• Surgery of the Liver Biliary Tract, and Pancreas 
  Chapter: Liver transplantation for cholangiocarcinoma and other neoplastic diseases. 
  Burns JM, Rosen CB, Heimbach JK, Gores GJEdition 5th,2012
• Medical care of the liver transplant patient. 
  Chapter: Cholangiocarcinoma. 
  Page 133 - 144Masuoka HC, Gores GJ, Rosen CBEditors: Clavien PA; Trotter JF; Mullhaupt B.Wiley-Blackwell, Chichester; HobokenEdition 4th,2012
• Molecular pathology of liver diseases. Molecular Pathology Library Series. 
  Chapter: Liver cell death. 
  Page 373 - 387Malhi H, Gores GJEditors: Monga SPS.Springer, New York2011
• Schiff's diseases of the liver. 
  Chapter: Mechanisms of liver injury. 
  Page 216 - 231Malhi H, Gores GJ2011
• Sleisenger and Fordtran's gastrointestinal and liver disease: pathophysiology, diagnosis, management. 
  Chapter: Tumors of the bile ducts, gallbladder, and ampulla. 
  Page 1171 - 1184Blechacz B, Gores GJEditors: Feldman M; Friedman LS; Brandt LJ.Saunders Elsevier, Philadelphia, PAEdition 9th,2010
• Signaling pathways in liver diseases. 
  Chapter: Fas/FasL. 
  Page 179 - 188Guicciardi ME, Gores GJ.Editors: Dufour JF; Clavien PA.Springer, New YorkEdition 2nd,2010
• Textbook of gastroenterology. Volume 2 
  Chapter: Hepatocellular carcinoma. 
  Page 2386 - 2411Roberts LR, Gores GJEditors: Yamada T, et al.Wiley Blackwell Publishing, Chichester; HobokenEdition 5th,2009
• Shackelford's surgery of the alimentary tract. Volume 2 
  Chapter: Primary sclerosing cholangitis. 
  Page 1560 - 1572Lazaridis KN, Gores GJEditors: Yeo CJ.Saunders, Philadelphia, PAEdition 6th,2007
• Schiff's diseases of the liver. 
  Chapter: of liver injury. 
  Page 313 - 328Malhi H, Gores GJEditors: Schiff ER, Sorrell MF, Maddrey WC.Lippincott Williams & Wilkins, Philadelphia, PAEdition 10th,2007
• Cell death during HIV infection. 
  Chapter: Regulation of apoptosis. 
  Page 21 - 33Guicciardi ME, Gores GJEditors: Badley AD.CRC/ Taylor & Francis, Boca Raton2006
• Oncology: an evidence-based approach. 
  Chapter: Cancer of the liver and bile ducts. 
  Page 745 - 763Kendrick ML, Grambihler A, Gores GJ, Alberts S, Nagorney DMEditors: Chang AE, et al.Springer, New York2006
• Therapy of digestive disorders. 
  Chapter: Cholangiocarcinoma and other biliary tumors. 
  Page 459 - 456Grambihler A, Gores GJEditors: Wolfe MM, et al.Saunders Elsevier, Philadelphia, PAEdition 2nd,2006
• Mayo Clinic gastroenterology and hepatology board review. 
  Chapter: Liver mass lesions. 
  Page 281 - 288Gores GJEditors: Hauser SC.Mayo Clinic Scientific Press, Rochester, MNEdition 2nd,2006
• Fas signaling. 
  Chapter: FasL and Fas in liver homeostasis and hepatic injuries. 
  Page 103 - 117Guicciardi ME, Gores GJEditors: Wajant H.Landes Bioscience/ Eurekah.com, Georgetown2006
• Apoptosis 2005. 
  Chapter: The lysolsomal pathway of apoptosis. 
  Page 57 - 76Guicciardi ME, Gores GJEditors: Scovassi AI.Research Signpost, Kerala2005
• Advanced therapy in gastroenterology and liver disease. 
  Chapter: Primary sclerosing cholangitis and cholangiocarcinoma. 
  Page 715 - 719Angulo P, Gores GJEditors: Bayless TM, Diehl AM.CRC/ Taylor & Francis, HamiltonEdition 5th,2005
• Clinical gastroenterology and hepatology. 
  Chapter: Cholangiocarcinoma. 
  Page 569 - 573Lazaridis KN, Gores GJ.Editors: Weinstein WM, Hawkey CJ, Bosch J.Elsevier Mosby, Edinburgh2005
• Signaling pathways in liver diseases. 
  Chapter: The Fas/FasL signaling pathway. 
  Page 129 - 138Guicciardi ME, Gores GJEditors: Dufour JF, Clavien PA.Springer, Berlin2005
• The pathophysiology of biliary epithelia. 
  Chapter: Apoptosis of biliary epithelial cells. 
  Page 219 - 226Torok NJ, Gores GJEditors: Alpini G, et al.Landes Bioscience/ Eurekah.com, Georgetown2004
• Encyclopedia of gastroenterology. Vol. 2 
  Chapter: Liver abscess. 
  Page 507 - 509Torok NJ, Gores GJEditors: Johnson LR.Elsevier Academic Press, Amsterdam2004
• Molecular pathogenesis of cholestasis. 
  Chapter: Bile acid-mediated apoptosis in cholestasis. 
  Page 126 - 134Higuchi H, Gores GJEditors: Trauner M, Jansen PLM.Landes Bioscience/ Eurekah.com, Georgetown2004
• Atlas of gastroenterology. 
  Chapter: Hepatocellular carcinoma. 
  Page 704 - 712Roberts LR, Gores GJEditors: Yamada T.Lippincott Williams & Wilkins, Philadelphia, PAEdition 3rd,2003
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Abstracts/Posters

• Bloodstream infections (bsi) in patients undergoing liver transplantation (lt) for hilar cholangiocarcinoma (cca).
  Ramanan P, Cummins N, Wilhelm M, Heimbach J, Dierkhising R, Kremers W, Rosen C, Gores G , Razonable R, Transplantation, 7/1/2014
• Intra-abdominal infections in patients undergoing liver transplantation (lt) for hilar cholangiocarcinoma (cca).
  Ramanan P, Cummins N, Wilhelm M, Heimbach J, Dierkhising R, Kremers W, Rosen C, Gores G , Razonable R, Transplantation, 7/1/2014
• Risk factors for infections in patients undergoing liver transplantation (lt) for hilar cholangiocarcinoma (cca).
  Ramanan P, Cummins N, Wilhelm M, Heimbach J, Dierkhising R, Kremers W, Rosen C, Gores G , Razonable R, Transplantation, 7/1/2014
• Caspase activation as a target for alcohol induced hepatic inflammation.
  Verma VK, Kamath PS, Gores GJ, Shah VH, Alcohol Clin Exp Res, 6/1/2014
• Bloodstream infections (bsi) in patients undergoing liver transplantation (lt) for hilar cholangiocarcinoma (cca).
  Ramanan P, Cummins N, Wilhelm M, Heimbach J, Dierkhising R, Kremers W, Rosen C, Gores G , Razonable R, Am J Transplant, 6/1/2014
• Intra-abdominal infections in patients undergoing liver transplantation (lt) for hilar cholangiocarcinoma (cca).
  Ramanan P, Cummins N, Wilhelm M, Heimbach J, Dierkhising R, Kremers W, Rosen C, Gores G , Razonable R, Am J Transplant, 6/1/2014
• Risk factors for infections in patients undergoing liver transplantation (lt) for hilar cholangiocarcinoma (cca).
  Ramanan P, Cummins N, Wilhelm M, Heimbach J, Dierkhising R, Kremers W, Rosen C, Gores G , Razonable R, Am J Transplant, 6/1/2014
• The development of a tailored pancreatobiliary fluorescence in situ hybridization (fish) assay to improve detection of malignancy in pancreatobiliary brushings.
  Barr Fritcher EG, Kipp BR, Voss JS, Brankley SM, Keeney ME, Campion MB, Pestova EV, Sokolova IA, Song M, Roberts LR, Gores G , Clayton AC, Halling KC, J Mol Diagn, 11/1/2013
• Ring-domain dependent degradation of ciap-1 contributes to hepatocyte lipoapoptosis.
  Akazawa Y, Guicciardi ME, Bronk S, Werneburg N, Nakao K, Charlton MR, Gores GJ, Hepatology, 10/1/2013
• Presence of portal vein encasement predicts efficacy of radiation therapy in the liver transplantation for perihilar cholangiocarcinoma protocol.
  Bhat M, Hathcock M, Kremers WK, Murad SD, Martenson J, Alberts S, Rosen CB, Gores GJ, Heimbach J, Hepatology, 10/1/2013
• Validation of immunohistochemistry-based classification of hepatic adenomas: different subtype distribution in a large US experience.
  Dhanasekaran R, Kang YN, Smoot R, Moser CD, Gores GJ, Wu TT, Mounajjed T, Roberts LR, Hepatology, 10/1/2013
• Serum immunoglobulin g4 levels in primary sclerosing cholangitis.
  Imam M, Lindor KD, Gores GJ, LaRusso NF, Chari S, Lazaridis K, Talwalkar JA, Hepatology, 10/1/2013
• Novel genetic model of cholangiocarcinoma in mice.
  Razumilava N, Yamada D, Bronk S, Li J, Bezerra JA, Chen X, Gores GJ, Hepatology, 10/1/2013
• Pdgf-bb induces apoptotic priming of cancer-associated fibroblasts in cholangiocarcinoma.
  Rizvi S, Mertens JC, Bronk SF, Werneburg NW, Dai HM, Roberts LR, Kaufmann SH, Gores GJ, Hepatology, 10/1/2013
• Canonical tgf-beta signaling drives tumor-progression via jak/stat3-signaling in advanced hcc.
  Rojas A, Cromheecke J, Xiao LC, Lee MH, Hung MC, Gores GJ, Blechacz B, Hepatology, 10/1/2013
• Long term patient and graft-related outcomes after liver transplantation for primary sclerosing cholangitis.
  Singh S, Talwalkar JA, Hay JE, Poterucha JJ, Gores GJ, Charlton MR, Rosen CB, Heimbach J, Wiesner RH, Hepatology, 10/1/2013
• Impact of highly effective antiviral therapy on the burden of hepatocellular carcinoma in hepatitis c cirrhosis.
  Kim WR, Congley SE, Roberts LR, Gores GJ, J Hepatol, 4/1/2013
• Hedgehog signaling contributes to chemotaxis in cholangiocarcinoma cells.
  Razumilava N, Smoot RL, Mertens JC, Gradilone SA, Bronk SF, Sirica AE, Gores GJ, J Hepatol, 4/1/2013
• Outcome of transplant fallout patients with unresectable cholangiocarcinoma.
  Sio TT, Martenson JA, Haddock MG, Gores GJ, Alberts SR, Heimbach JK, Rosen CB, Int J Radiat Oncol Biol Phys, 11/1/2012
• Proctocolectomy is associated with development of cholangiocarcinoma among patients with primary sclerosing cholangitis and ulcerative colitis.
  Lammert C, Tabibian JH, Adebajo CO, Imam M, Talwalkar J, Gores GJ, Hepatology, 10/1/2012
• Therapeutic targeting of cancer-associated fibroblasts in cholangiocarcinoma.
  Mertens JC, Fingas CD, Christensen JD, Kakisaka K, Smoot R, Bronk SF, Mott JL, Gustafson MP, Dietz AB, Roberts LR, Sirica AE, Gores GJ, Hepatology, 10/1/2012
• An autocrine requirement for hedgehog signaling in cholangiocarcinogenesis.
  Razumilava N, Smoot R, Mertens JC, Bronk SF, Sirica AE, Gores GJ, Hepatology, 10/1/2012
• The impact of multiple tace treatments on hcc for patients awaiting liver transplantation.
  Terzi E, Kim WR, Sanchez W, Charlton M, Gores GJ, Heimbach J, Hepatology, 10/1/2012
• IDH1 and IDH2 mutations detected by pyrosequencing in cholangiocarcinoma.
  Voss JS, Kerr SE, Barr Fritcher EG, Highsmith WE, Zhang J, Roberts LR, Gores GJ, Halling KC, Kipp BR, Lab Invest, 2/1/2012
• IDH1 and IDH2 mutations detected by pyrosequencing in cholangiocarcinoma.
  Voss JS, Kerr SE, Barr Fritcher EG, Highsmith WE, Zhang J, Roberts LR, Gores GJ, Halling KC, Kipp BR, Mod Pathol, 2/1/2012
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Lectures

• PG Course 
  Boston, MA - 1/1/2010
• Monothematic Conference 
  Oslo, Norway - 1/1/2009
• Academic Skills Workshop 
  Phoenix, AZ - 1/1/2009
• Transplant Hepatology 
  Chicago, IL - 1/1/2008
• Future Trends Workshop 
  Washington, DC - 1/1/2008
• Future Trends 
  Washington, DC - 1/1/2008
• Endpoints Conference on PBC 
  Atlanta, GA - 1/1/2008
• Therapy in Liver Disease 
  Barcelona, Spain - 1/1/2007
• Liver Fibrosis Update 
  Essen, Germany - 1/1/2007
• Human Genome Sciences 
  Gaithersburg, MD - 1/1/2007
• CAQ Board Review Course 
  Chicago, IL - 1/1/2006
• Fibrosis 
  Warrington, VA - 1/1/2006
• Celera 
  San Francisco, CA - 1/1/2003
• Therapy in Liver Diseases 
  Rome, Italy - 1/1/2003
• Experimental Biology 
  Orlando, FL - 1/1/2001
• Hepatology 2000 
  Munich, Germany - 1/1/2000
• Liver Transplantation 
  Dallas, TX - 1/1/2000
• Hepatoxicity 
  1/1/2000
• Hepatocellular Carcinoma 
  St. Louis, MO - 1/1/1998
• Cell Biology of Hypoxia 
  Gaithersburg, MD - 1/1/1996
• Bile Acids and the Future 
  Desert Springs, CA - 1/1/1993
• Study of Acute Hepatic Failure 
  Tokyo, Japan - 1/1/1992
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Other

• Cell Death: Suicide vs. Murder. Postgraduate Course of the American Association for the Study of Liver Diseases. 
  Gores GJ, SLACK/SPN Interactive
  1/1/1997
• Hot Topics in Gastroenterology: Mass in the liver. 
  Gores GJ, Prime Practive: A CD-ROM series for Primary Care Practitioners, Vol. 2, No. 2
  1/1/1996
• Neoplastic cholangiopathies. 1996 Postgraduate Course of the Ameican Association for the Study of Liver Diseases. 
  Gores GJ, SLACK/SPN Interactive
  1/1/1996
• Apoptosis. The Best of the AASLD. 
  Gores GJ, Slack/Cd-Stat
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