GraceAMccomseyMD

Infectious Disease • Cleveland, OH

HIV/AIDS Medicine, Transplant/Immunocompromised States

Professor, Pediatrics and Medicine, Case Western Reserve University School of Medicine

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Office
UH Rainbow Babies and Children's Hospital
2061 Cornell Rd Department of Pediatrics-Infectious Diseases
Cleveland, OH 44106
Phone+1 216-844-7892

Fax+1 216-844-5356
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Education & Training

Case Western Reserve University/University Hospitals Cleveland Medical CenterFellowship, Infectious Disease, 1994 - 1997
The MetroHealth System/Case Western Reserve UniversityResidency, Internal Medicine, 1991 - 1994
St Joseph's University Medical SchoolClass of 1989

Certifications & Licensure

OH State Medical License 1993 - 2026
American Board of Internal Medicine Infectious Disease
American Board of Pediatrics Pediatric Infectious Diseases

Awards, Honors, & Recognition

America's Top Doctor 2015-2023
America's Top Doctors Castle Connolly, 2012-2014

Clinical Trials

Use of Muscle Spectroscopy to Evaluate Mitochondrial Dysfunction in HIV-Infected Patients
Withdrawn
A Study to See if Certain Antioxidants and Vitamins Will Keep Lactate Levels Down in Patients Taking Anti-HIV Drugs
Withdrawn
Not Applicable
The Effect of Alendronate, Calcium, and Vitamin D on Bone Mineral Density in HIV Infected Patients
Completed
Phase 2
Effectiveness of Nucleoside Supplementation or Switch to Tenofovir in Reversing Fat Loss in HIV Infected Adults Start of enrollment: 2005 Apr 01
Completed
Phase 2
Observational Study of Fat Loss in HIV Infected Adults Taking Nucleoside Reverse Transcriptase Inhibitors (NRTIs) Start of enrollment: 2005 Apr 01
Completed
Effects of a Uridine Supplement on HIV Infected Adults With Lipoatrophy Start of enrollment: 2006 Sep 01
Completed
Phase 2, Phase 3
Rosiglitazone Effect on Mitochondria and Lipoatrophy Start of enrollment: 2006 Jul 01
Completed
Phase 2
Metabolic Effects of Non-Thymidine Analogue Anti-HIV Medications Start of enrollment: 2006 Apr 01
Completed
Antiretrovirals and Rate of Progression in Carotid Artery Intima-medial Thickness in HIV Start of enrollment: 2007 Nov 01
Completed
Raltegravir Therapy for Women With HIV and Fat Accumulation Start of enrollment: 2008 Sep 01
Completed
Phase 2
Comparative Study of Three NNRTI-Sparing HAART Regimens Start of enrollment: 2009 May 01
Completed
Phase 3
Pilot Placebo Controlled Study With Lovaza in Cardiovascular Disease Start of enrollment: 2009 Apr 01
Completed
Phase 2
Safety and Efficacy of Salsalate to Treat Endothelial Dysfunction in HIV-infected Adults Start of enrollment: 2009 Jan 01
Completed
Phase 2
Use of Rosuvastatin in HIV-Infected Subjects to Modulate Cardiovascular Risks Start of enrollment: 2011 Feb 01
Completed
Phase 2
Vitamin D and HIV-Cardiovascular Disease in Children and Young Adults Start of enrollment: 2011 Sep 01
Completed
Vitamin D Supplementation in HIV Youth Start of enrollment: 2011 Dec 01
Completed
Phase 2, Phase 3
The Cleveland Cardiometabolic Cohort Start of enrollment: 2016 Sep 01
Recruiting
Effect of Heroin Use on Immune Activation and Cardiovascular Risk in HIV Start of enrollment: 2017 Jul 14
Completed
Effects of Semaglutide in HIV-Associated Lipohypertrophy Start of enrollment: 2019 May 16
Active, not recruiting
Phase 2
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Publications & Presentations

PubMed

400 citations
Weight Gain Following Initiation of Antiretroviral Therapy: Risk Factors in Randomized Comparative Clinical Trials
Paul E. Sax, Kristine M. Erlandson, Jordan E. Lake, Grace A. McComsey, Chloe Orkin
Clinical Infectious Diseases. 2020-09-12
119 citations
Weight gain and integrase inhibitors.
Allison Ross Eckard, Grace A. McComsey
Current Opinion in Infectious Diseases. 2020-02-01
171 citations
Association between systemic inflammation and incident diabetes in HIV-infected patients after initiation of antiretroviral therapy
Todd T. Brown, Katherine Tassiopoulos, Ronald J. Bosch, Cecilia M. Shikuma, Grace A. McComsey
Diabetes Care. 2010-10-01

Press Mentions

“Long COVID” Evades Common SARS-CoV-2 Clinical Lab TestsAugust 13th, 2024
There's No Good Lab Test to Spot Long COVIDAugust 13th, 2024
Largest Study of Its Kind Finds Common Lab Tests Aren’t Reliable for Diagnosing Long COVIDAugust 12th, 2024
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Grant Support

Vitamin D, Drug Metabolism, And Cardiovascular Complications In Pediatric HIVEunice Kennedy Shriver National Institute Of Child Health &Human Development2011
Inflammation, Heart And BoneNational Institute Of Nursing Research2010–2011
Research Training In Pediatric Infectious DiseasesNational Institute Of Allergy And Infectious Diseases2008–2011
Metabolic Consequences Of Thymidine Sparing RegimensNational Institute Of Allergy And Infectious Diseases2006–2010
Role Of Mitochondria In HIV LipoatrophyNational Institute Of Allergy And Infectious Diseases2005–2009
Uridine Supplementation For HIV LipoatrophyNational Center For Complementary &Alternative Medicine2005–2007
Training Program In Pediatric Infectious DiseasesNational Institute Of Allergy And Infectious Diseases2004–2006
Role Of Mitochondria In HIV LipoatrophyNational Institute Of Allergy And Infectious Diseases2004
Longitudinal Assessment Of Mtdna Kinetics In PTS On Nrti-Containing HaartNational Center For Research Resources2004