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Goutham Narla, MD, Medical Genetics, Ann Arbor, MI

GouthamNarlaMDPHD

Medical Genetics Ann Arbor, MI

Clinical Genetics

Assistant Professor

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  • Office

    1500 E Medical Center Dr
    Rogel Cancer Center, Rm 3215
    Ann Arbor, MI 48109
    Phone+1 734-615-2411

Summary

  • I am physician scientist who specializes in the care of high risk cancer genetics patients. I run a translational cancer research laboratory focused on identifying and characterizing the genetic regulators of cancer development and progression and developing targeted molecular therapies to these alterations.

Education & Training

  • Mt Sinai SOM
    Mt Sinai SOM2008 - 2012
  • Mount Sinai Hospital
    Mount Sinai Hospital2008 - 2011
  • Icahn School of Medicine at Mount Sinai/Mount Sinai Hospital
    Icahn School of Medicine at Mount Sinai/Mount Sinai HospitalInternship, Internal Medicine, 2006 - 2008
  • Mount Sinai School of Medicine
    Mount Sinai School of MedicinePh.D, Cancer Biology/Genetics, 2001 - 2006
  • Icahn School of Medicine at Mount Sinai
    Icahn School of Medicine at Mount SinaiClass of 2006, MD
  • Santa Clara University
    Santa Clara UniversityBS, Biology/Economics, 1993 - 1997

Certifications & Licensure

  • MI State Medical License
    MI State Medical License 2018 - 2025
  • OH State Medical License
    OH State Medical License 2012 - 2021
  • NY State Medical License
    NY State Medical License 2008 - 2013

Awards, Honors, & Recognition

  • Harrington Scholarship 2012
  • Saul Horowitz, Jr. Memorial Award 2010
  • Humanism and Excellence in Teaching, Arnold P. Gold Foundation 2008
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Publications & Presentations

PubMed

Journal Articles

  • Increased alternative splicing of the KLF6 tumor suppressor gene correlates with prognosis and tumor grade in patients with pancreatic cancer.  
    Hartel M, Narla G, Wente MN, Giese NA, Martignoni ME, Martignetti JA, Friess H, Friedman SL, Eur J Cancer; 44:1895-903
  • RAS/PI3-K/AKT promotes cellular growth by enhancing alternative splicing-mediated inactivation of the KLF6 tumor suppressor in human hepatocellular carcinoma.  
    Yea S, Narla G, Zhao X, Villanueva A, Martignetti JA, Llovet JM, Friedman SL, Hepatology ;46:303A-4A
  • Drosophila Sin3a mediates cancer-like invasion through multiple pathways.  
    Das TK, Sangodkar J, Negre N, Narla G, and Cagan RL, Cancer Cell
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Books/Book Chapters

Abstracts/Posters

  • PP2A Activators Enhance Efficacy of FLT3 Inhibitors in FLT3-ITD Acute Myeloid Leukemia Cells through AKT Inactivation-Dependent Pim-1 and c-Myc Proteasomal Degradation
    Goutham Narla, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
  • Divergent roles of matrix metalloproteinase-2 in hepatic stellate cell activation and liver fibrosis.
    Radbill B, Gupta R, Alvarez C, Narla G, Martignetti J, Friedman SL, Bansal MB, Hepatology ;40:546A-A
  • KLF6 Deficiency Promotes Hepatocellular Carcinoma in Mice and Humans by Increasing Mdm2 Expression and Accelerating P53 Degradation.
    21. Tarocchi M, Lee UE, Hannivoort R, Loke JC, Narla G, Villanueva A, Llovet JM, Friedman SL, Hepatology ;50:366A-7A
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Lectures

  • Cancer Genetics: Past, Present, and Future. 
    Grand Rounds Seminar, Department of Medicine, Mount Sinai School of Medicine, New York, NY
  • The Role of Alternative Splicing in the Regulation of the KLF6 Tumor Suppressor Gene. 
    Fred Hutchinson Cancer Research Center, Seattle, WA
  • Personalized Medicine and Lung Cancer Treatment. 
    Charles R. Bronfman Institute for Personalized Medicine, Mount Sinai School of Medicine, New York
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Press Mentions

  • Researchers Zero in on Therapeutic Target for Aggressive Uterine Cancer
    Researchers Zero in on Therapeutic Target for Aggressive Uterine CancerDecember 17th, 2021
  • Rappta Therapeutics Appoints Sunjeet Sawhney as Chief Executive Officer
    Rappta Therapeutics Appoints Sunjeet Sawhney as Chief Executive OfficerSeptember 15th, 2021
  • Case Western Reserve School of Medicine Awarded $1.6 Million for Undergraduate Research
    Case Western Reserve School of Medicine Awarded $1.6 Million for Undergraduate ResearchNovember 6th, 2018
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Professional Memberships

  • AACR
    Member

Other Languages

  • Spanish, French