GordonHaroldWilliamsMD

PubMed

• 251 citations
  Mineralocorticoid receptor blockade reverses obesity-related changes in expression of adiponectin, peroxisome proliferator-activated receptor-gamma, and proinflammator...
  Christine Guo, Vincent Ricchiuti, Bill Q. Lian, Tham M. Yao, Patricia Coutinho
  Circulation. 2008-04-29
• 4 citations
  Combined Salt and Caloric Restrictions: Potential Adverse Outcomes.
  Tsuyoshi Homma, Mika Homma, Yuefei Huang, Korapat Mayurasakorn, Nurul Mahamad Rodi
  Journal of the American Heart Association. 2017-10-11
• 11 citations
  Caloric restriction improves glucose homeostasis, yet increases cardiometabolic risk in caveolin-1-deficient mice.
  Korapat Mayurasakorn, Nurul Hasanah, Tsuyoshi Homma, Mika Homma, Isis Katayama Rangel
  Metabolism. 2018-06-01

Journal Articles

• Inner Ear Pathologies Impair Sodium-Regulated Ion Transport in Meniere’s Disease  
  Gordon H Williams, Steven D Rauch, Acta Neuropathologica
• Caveolin 1 Modulates Aldosterone-Mediated Pathways of Glucose and Lipid Homeostasis  
  Baudrand R, Gupta N, Garza AE, Vaidya A, Leopold JA, Hopkins PN, Jeunemaitre X, Ferri C, Romero JR, Williams J, Loscalzo J, Adler GK, Williams GH, Pojoga LH, J Am Heart Assoc, 1/28/2016
• Treatment with patiromer decreases aldosterone in�patients with chronic kidney disease and hyperkalemia on renin-angiotensin system inhibitors  
  Weir MR, Bakris GL, Gross C, Mayo MR, Garza D, Stasiv Y, Yuan J, Berman L, Williams GH, Kidney Int, 1/1/2016
• A prevalent caveolin-1 gene variant is associated with the metabolic syndrome in Caucasians and Hispanics  
  Baudrand R, Goodarzi MO, Vaidya A, Underwood PC, Williams JS, Jeunemaitre X, Hopkins PN, Brown N, Raby BA, Lasky-Su J, Adler GK, Cui J, Guo X, Taylor KD, Chen YD, Xian..., Metabolism, 1/1/2015
• Patiromer induces rapid and sustained potassium lowering in patients with chronic kidney disease and hyperkalemia  
  Bushinsky DA, Williams GH, Pitt B, Weir MR, Freeman MW, Garza D, Stasiv Y, Li E, Berman L, Bakris GL, Kidney Int, 1/1/2015
• Cooperative Role of Mineralocorticoid Receptor and Caveolin-1 in Regulating the Vascular Response to Low Nitric Oxide-High Angiotensin II-Induced Cardiovascular Injury  
  Pojoga LH, Yao TM, Opsasnick LA, Siddiqui WT, Reslan OM, Adler GK, Williams GH, Khalil RA, J Pharmacol Exp Ther, 1/1/2015
• Critical Role of Striatin in Blood Pressure and Vascular Responses to Dietary Sodium Intake  
  Garza AE, Pojoga LH, Moize B, Hafiz WM, Opsasnick LA, Siddiqui WT, Horenstein M, Adler GK, Williams GH, Khalil RA, Hypertension, 1/1/2015
• Statins and muschloskeletal adverse events  
  Baudrand R and Williams GH, JAMA Intern Med, 1/1/2014
• No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels  
  Scott RA, Chu AY, Grarup N, Manning AK, Hivert MF, Shungin D, Tonjes A, Yesupriya A, Barnes D, Bouatia-Naji N, Glazer NL, Jackson AU, Kutalik Z, Lagou V, Marek D, Rasm..., Diabetes, 1/1/2012
• Altered systemic hemodynamic and baroreflex response to angiotensin II in postural tachycardia syndrome  
  Mustafa HI, Raj SR, Diedrich A, Black BK, Paranjape SY, Dupont WD, Williams GH, Biaggioni I, Robertson D, Circ Arrhythm Electrophysiol, 1/1/2012
• Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women  
  Fox CS, Liu Y, White CC, Feitosa M, Smith AV, Heard-Costa N, Lohman K; GIANT Consortium; MAGIC Consortium; GLGC Consortium, Johnson AD, Foster MC, Greenawalt DM, Griff..., PLoS Genet, 1/1/2012
• The association of plasma resistin with dietary sodium manipulation, the renin-angiotensin-aldosterone system, and 25-hydroxyvitamin D3 in human hypertension  
  Vaidya A, Pojoga L, Underwood PC, Forman JP, Hopkins PN, Williams GH, Williams JS, Clin Endocrinol, 1/1/2011
• Dietary sodium intake regulates angiotensin II type 1, mineralocorticoid receptor, and associated signaling proteins in heart  
  Ricchiuti V, Lapointe N, Pojoga L, Yao T, Tran L, Williams GH, Adler GK, J Endocrinol, 1/1/2011
• Mineralocorticoid receptor expression in human venous smooth muscle cells: a potential role for aldosterone signaling in vein graft arterialization  
  Bafford R, Sui XX, Park M, Miyahara T, Newfell BG, Jaffe IZ, Romero JR, Adler GK, Williams GH, Khalil RA, Conte MS, Am J Physiol Heart Circ Physiol, 1/1/2011
• A double-blind, randomized study comparing the antihypertensive effect of eplerenone and spironolactone in patients with hypertension and evicence of primary aldostero...  
  Parthasarathy HK, Menard J, White WB, Young WF Jr, Williams GH, Williams B, Ruilope LM, McInnes GT, Connell JM, MacDonald TM, J Hypertens, 1/1/2011
• Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits  
  Speliotes EK et. al. (MAGIC investigators), PLoS Genet, 1/1/2011
• Histone demethylase LSD1 deficiency during high-salt diet is associated with enhanced vascular contraction, altered NO-cGMP relaxation pathway, and hypertension  
  Pojoga LH, Williams JS, Yao TM, Kumar A, Raffetto JD, do Nascimento GR, Reslan OM, Adler GK, Williams GH, Shi Y, Khalil RA, Am J Physiol Heart Circ Physiol, 1/1/2011
• Mineralocorticoid receptor expression in human venous smooth muscle cells: Mineralocorticoid receptor expression in human venous smooth muscle cells: a potential role ...  
  Bafford R, Sui XX, Park M, Miyahara T, Newfell BG, Jaffe IZ, Romero JR, Adler GK, Williams GH, Khalil RA, Conte MS, Am J Physiol Heart Circ Physiol, 1/1/2011
• The Fok1 vitamin D receptor gene polymorphism is associated with plasma renin activity in Caucasians  
  Vaidya A, Sun B, Forman JP, Hopkins PN, Brown NJ, Kolatkar NS, Williams GH, Williams JS, Clin Endocrinol (Oxf), 1/1/2011
• A double-blind, randomized study comparing the antihypertensive effect of eplerenone and spironolactone in patients with hypertension and evidence of primary aldostero...  
  Parthasarathy HK, Menard J, White WB, Young WF Jr, Williams GH, Williams B, Ruilope LM, McInnes GT, Connell JM, MacDonald TM, J Hypertens, 1/1/2011
• The influence of body mass index and renin-angiotensin-aldosterone system activity on the relationship between 25-hydroxyvitamin D and adiponectin in Caucasian men  
  Vaidya A, Forman JP, Underwood PC, Hopkins PN, Williams GH, Pojoga LH, Williams JS, Eur J Endocrinol, 1/1/2011
• The association of plasma resistin with dietary sodium manipulation, the renin-angiotensin-aldosterone system, and 25-hydroxyvitamin D3 in human hypertension  
  Vaidya A, Pojoga L, Underwood PC, Forman JP, Hopkins PN, Williams GH, Williams JS, Clin Endocrinol (Oxf), 1/1/2011
• Cell membrane-associated mineralocorticoid receptors? New evidence  
  Krug AW, Pojoga LH, Williams GH, Adler GK, Hypertension, 1/1/2011
• A mechanism for salt-sensitive hypertension: abnormal dietary sodium-mediated vascular response to angiotensin-II  
  Chamarthi B, Williams JS, Williams GH, J Hypertens, 1/1/2010
• Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans  
  Ingelsson E et. al. MAGIC investigators, Diabetes, 1/1/2010
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Books/Book Chapters

• The Teaching Hospital, Brigham and Women's Hospital and the Evolution of Academic Medicine 
  Chapter: George Widmer Thorn 
  Page 24 - 25Williams GHEditors: Tishler PV, Wenc C and Loscalzo J.McGraw Hill, New York2014
• Primer on the Autonomic Nervous System 
  Chapter: Altered Adrenal Function and the Autonomic Nervous System. 
  Page 571 - 574Trikudanathan S and Williams GHEditors: Robertson D, Biaggioni I, Burnstock G, Low PA and Paton JFR.Academic Press, LondonEdition 3rd,2012
• Pathophysiology of Heart Disease 
  Chapter: Hypertension 
  Page 301 - 323Lee CT, Williams GH, Lilly LSEditors: Lilly LS.Wolters Kluwer/Lippincott Williams & Wilkins, PhiladelphiaEdition 5th,2011
• Harrison's Endocrinology 
  Chapter: Disorders of the Adrenal Cortex 
  Page 113 - 150Williams GH and Dluhy RGEditors: Jameson JL.McGraw Hill, New York2006
• Williams Textbook of Endocrinology 
  Chapter: Endocrine Hypertension 
  Page 552 - 585Dluhy RG, Lawrence JE, Williams GHEditors: Larsen PR, Kronenberg HM, Melmed S, Polonsky KS.Saunders, PhiladelphiaEdition 10th,2003
• Pathophys of Heart Disease: A Collaborative Project of Medical Students and Faculty 
  Chapter: Hypertension 
  Page 289 - 310Malhotra R, Williams GH, Lilly LSEditors: Lilly LS.Lippincott, Williams and Wilkins, PhiladelphiaEdition 3rd,2003
• Harrison's Principles of Internal Medicine 
  Chapter: Hypertensive Vascular Disease 
  Williams GHEditors: Braunwald E, Fauci AS, Kasper DL, Hauser SL, Longo DL, Jameson JL.McGraw-Hill, New YorkEdition 15th,2001
• Harrison's Principles of Internal Medicine 
  Chapter: Approach to the patient with hypertension. 
  Williams GHEditors: Braunwald E, Fauci AS, Kasper DL, Hauser SL, Longo DL, Jameson JL.McGraw-Hill, New YorkEdition 15th,2001
• Heart Disease: A Textbook of Cardiovascular Medicine 
  Chapter: The heart in endocrine disorders. 
  Page 2151 - 271Williams GH, Seely EWEditors: Braunwald E, Zipes DP, Libby P.WB Saunders Company, PhiladelphiaEdition 6th,2001
• Harrison's Principles of Internal Medicine 
  Chapter: Disorders of the adrenal cortex. 
  Page 2084 - 2105Williams GH, Dluhy RGEditors: Braunwald E, Fauci AS, Kasper DL, Hauser SL, Longo DL, Jameson JL.McGraw-Hill, New YorkEdition 15th,2001
• Endocrinology 
  Chapter: Aldosterone action. 
  Page 1783 - 1790Mortensen RM, Williams GHEditors: DeGroot LJ, Jameson JL, Burger HG, Loriaux DL, Marshall JC, Melmed S, Odell WD, Potts JT, Jr., Rubenstein AH.WB Saunders Company, PhiladelphiaEdition 4th,2001
• Prin and Pract of Endo and Meta 
  Chapter: The cardiovascular system and endocrine disease. 
  Page 1857 - 1864Seely EW, Williams GHEdition 3rd,2001
• Heart Disease: A Textbook of Cardio Med 
  Chapter: The heart in endocrine disorders. 
  Page 2151 - 2171Seely EW, Williams GHEditors: Braunwald E, Zipes, Libby P.Edition 6th,2001
• Williams Textbook of Endocrinology 
  Chapter: Endocrine hypertension. 
  Dluhy RG, Williams GHEditors: Wilson JD, Foster DW, Larsen PR, Kronenberg H.Edition 9th,1998
• Cardiovascular Research 
  Chapter: Glucocorticoid-remediable aldosteronism. 
  Dluhy RG, Williams GHElsevier Science BV, Amsterdam1998
• Atlas of Heart Diseases, Volume 1: Hypertension: Mechanisms and Therapy 
  Chapter: Antihypertensive therapy: Compliance and quality of life. 
  Williams GHEditors: Hollenberg NK.Current Medicine, PhiladelphiaEdition 2nd,1998
• Current Therapy in Adult Medicine 
  Chapter: Primary aldosteronism. 
  Page 1230 - 1234Adler GK, Williams GHEditors: Kassirer JP, Greene HL II.Mosby-Year Book, Inc., St. LouisEdition 4th,1997
• Heart Disease: A Textbook of Cardiovascular Medicine 
  Chapter: The heart in endocrine and nutritional disorders. 
  Page 1887 - 1913Williams GH, Lilly LS, Seely EWEditors: Braunwald E.WB Saunders Company, PhiladelphiaEdition 5th,1997
• Current Practice of Medicine 
  Chapter: Aldosteronism and endocrine blood pressure syndromes. 
  Page 1 - 6Dluhy RG, Williams GHEditors: Bone RC.Philadelphia1996
• Endocrinology: Basic and Clinical Principles 
  Chapter: Kidney hormones. The kallikrein-kinin and renin-angiotensin system. 
  Page 393 - 404Williams GH, Chao J, Chao LEditors: Conn PM, Melmed S.Humana Press Inc., Totowa, NJ1996
• Cardiovascular Therapeutics: A Companion to Braunwald's Heart Disease 
  Chapter: Secondary hypertension: causes and treatment. 
  Page 536 - 537Williams GHEditors: Smith TW.WB Saunders Company, Philadelphia1996
• Aging, Health, and Healing 
  Chapter: Quality of life considerations in therapeutic decision making: Antihypertensive therapy as a model. 
  Page 257 - 266Williams GHEditors: Bergener M, Brocklehurst JC, Finkel SI.Springer Publishing Company, Inc., New York1995
• Hypertension: Pathophysiology, Diagnosis, and Management, 
  Chapter: Abnormal renal function, sodium-volume homeostasis and renin system behavior in normal-renin essential hypertension: The evolution of the non-modulator concept. 
  Page 1837 - 1856Hollenberg NK, Williams GHEditors: Laragh JH, Brenner BM.Raven Press, Ltd., New YorkEdition 2nd,1995
• Atlas of Heart Disease 
  Chapter: Antihypertensive therapy: compliance, quality of life and economic issues. 
  Williams GHEditors: Braunwald E.Current Medicine, Philadelphia1995
• Hypertension: Pathophysiology, Diagnosis and Management 
  Chapter: Abnormal renal function, sodium-volume homeostasis and renin system behavior in normal-renin essential hypertension: The evolution of the nonmodular concept. 
  Page 1837 - 1856Hollenberg NK, Williams GHEditors: Laragh JH, Brenner BM.Raven Press, Ltd., New YorkEdition 2nd,1995
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Other

• Non-invasive assessment of alterations in cardiovascular regulation and function and susceptibility to ventricular arrhythmias resulting from microgravity exposure. 
  Ramsdell CD, Sundby GH, Sherman D, Maa M, Baskin JL, Williams GH, Cohen RJ, Space Technology and Applications International Forum: American Institute of Physics (pp. 281-294)
  1/1/2000
• Steroid receptor specificity with reference to the estrogen receptor. 
  Williams GH, Estrogen and estrogen-like substances in Women's Health: Osteoporosis Int (Lindsay R, Meunier PJ, ed
  1/1/1997
• Nephropathy and neuropathy: Long-term complications of diabetic care. 
  Williams GH, Drug Therapy
  1/1/1993
• Quality of life as a therapeutic end-point: an analysis of therapeutic trials in hypertension. 
  Hollenberg NK, Testa M, Williams GH, Drug Safety
  1/1/1991
• A fully automated robotic system for the radioimmunoassay of steroid and peptide hormones using "coated tube" and "coated bead" techniques in an endocrine research lab... 
  Underwood RH, Bradwin GR, Williams GH, Proc 8th International Symposium on Laboratory Automation and Robotics
  Boston - 1/1/1990
• Quality of life of the hypertensive patient. 
  Williams GH, Am Osteopath Assoc
  1/1/1987
• Quality of life considerations in the hypertensive patient. 
  Williams GH, Drug Therapy
  1/1/1987
• Potassium-sparing diuretics: clinical pharmacology and therapeutic uses. 
  Shoback DM, Williams GH, Drug Therapy
  1/1/1982
• Adrenal causes of hypertension. 
  Dluhy RG, Williams GH, Medical Times
  1/1/1980
• Adrenal function as a consideration in anesthesia. 
  Williams GH, Weekly Anesthesiology Update
  1/1/1978
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