GlennJLesserMD

Oncology • Winston Salem, NC

Neuro-Oncology

Professor of Hematology & Oncology, Wake Forest University

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Office
S Hawthorne Rd
Winston Salem, NC 27157
Phone+1 336-716-2255

Summary

Glenn Lesser, MD, is an oncologist based in Winston Salem, NC, who specializes in Neuro-Oncology and symptom science. He attended Pennsylvania State University College of Medicine and completed his residency at Wake Forest University Baptist Medical Center and his oncology fellowship at the Johns Hopkins Oncology Center. His practice is focused in the areas of neuro-oncology, symptom managemen, and general medical oncology. Dr. Lesser has over 180 publications and has been the principal investigator on over 120 clinical trials involving treatment for high-grade gliomas and symptom management for cancer survivors. He has received multiple awards, including America's Top Doctors from Castle Connolly for a period exceeding a decade.

Education & Training

Johns Hopkins UniversityFellowship, Hematology and Medical Oncology, 1991 - 1994
Wake Forest University Baptist Medical CenterResidency, Internal Medicine, 1987 - 1991
Pennsylvania State University College of MedicineClass of 1987

Certifications & Licensure

NC State Medical License 1995 - 2026
VA State Medical License 1994 - 2012
MD State Medical License 1991 - 1996
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2009-2024
America's Top Doctors for Cancer Castle Connolly, 2005-2021
CMS Meaningful Use Stage 1 Certification EpicCare Inpatient - Core EMR, Epic Systems Corporation, 2013

Clinical Trials

Pyrazoloacridine Followed by Radiation Therapy in Treating Adults With Newly Diagnosed Supratentorial Glioblastoma Multiforme Start of enrollment: 2000 May 01
Completed
Phase 1, Phase 2
Oxandrolone Compared With Megestrol in Preventing Weight Loss in Patients Receiving Chemotherapy for Cancer Start of enrollment: 2004 Mar 01
Completed
Phase 3
Thalidomide and Procarbazine in Treating Patients With Recurrent or Progressive Malignant Glioma Start of enrollment: 2004 Jan 01
Completed
Phase 2
Coenzyme Q10 in Relieving Treatment-Related Fatigue in Women With Breast Cancer Start of enrollment: 2004 Aug 27
Completed
Phase 1
Temozolomide and Radiation Therapy in Treating Patients With Gliomas Start of enrollment: 2005 Jan 01
Completed
Phase 2
Changes in Semen or Sperm Caused by Temozolomide in Patients With Newly Diagnosed, Progressive, or Recurrent Primary Malignant Brain Tumors Start of enrollment: 2004 Aug 01
Completed
Safety and Dose-Finding Study of TM-601 in Adults With Recurrent Malignant Glioma Start of enrollment: 2008 Feb 01
Unknown status
Phase 1
ABT-888, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme Start of enrollment: 2009 Jul 13
Completed
Phase 1
Ramucirumab or Anti-PDGFR Alpha Monoclonal Antibody IMC-3G3 in Treating Patients With Recurrent Glioblastoma Multiforme Start of enrollment: 2010 Jul 01
Completed
Phase 2
Erlotinib Hydrochloride and Isotretinoin in Treating Patients With Recurrent Malignant Glioma Start of enrollment: 2010 May 01
Terminated
Phase 1
Mibefradil Dihydrochloride and Temozolomide in Treating Patients With Recurrent Glioma Start of enrollment: 2012 May 31
Completed
Phase 1
A Study of Rindopepimut/GM-CSF in Patients With Relapsed EGFRvIII-Positive Glioblastoma Start of enrollment: 2011 Dec 01
Completed
Phase 2
Bovine Lactoferrin in Reducing Taste Disturbances in Patients With Colorectal Cancer Receiving Oxaliplatin-Based Chemotherapy Start of enrollment: 2013 Jan 01
Completed
Not Applicable
Adavosertib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma Start of enrollment: 2013 Aug 19
Active, not recruiting
Phase 1
Bovine Lactoferrin Supplement in Improving Taste in Patients With Cancer Receiving Chemotherapy Start of enrollment: 2014 Feb 01
Completed
Not Applicable
Sapanisertib Before and After Surgery in Treating Patients With Recurrent Glioblastoma Start of enrollment: 2014 Jul 02
Terminated
Phase 1
Electronic Medical Record Review in Monitoring the Effects of Adherence on Myelosuppression and Morbidity in Patients With Newly Diagnosed Brain Tumors Receiving Temozolomide and Radiation Therapy Start of enrollment: 2010 Oct 01
Completed
Terameprocol in Treating Patients With Recurrent High Grade Glioma Start of enrollment: 2018 May 03
Completed
Phase 1
Study of the Effect NT-I7 on CD4 Counts in Patients With High Grade Gliomas Start of enrollment: 2018 Oct 30
Terminated
Phase 1
Testing Ramipril to Prevent Memory Loss in People With Glioblastoma Start of enrollment: 2019 Mar 25
Active, not recruiting
Phase 2
Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer Start of enrollment: 2019 Sep 23
Recruiting
An Internet-based Program to Help Cancer Survivors Manage Pain Start of enrollment: 2021 May 13
Recruiting
Not Applicable
Pivotal, Randomized, Open-label Study of Optune® (Tumor Treating Fields) Concomitant With RT & TMZ for the Treatment of Newly Diagnosed GBM Start of enrollment: 2020 Dec 08
Active, not recruiting
Not Applicable
Roles: Contact
Multiple Doses of Neural Stem Cell Virotherapy (NSC-CRAd-S-pk7) for the Treatment of Recurrent High-Grade Gliomas Start of enrollment: 2023 May 02
Recruiting
Phase 1
Roles: Contact
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Publications & Presentations

PubMed

2 citations
The National Cancer Institute clinical trials planning meeting to address gaps in observational and intervention trials for cancer-related cognitive impairment.
Michelle C Janelsins, Kathleen Van Dyk, Sheri J Hartman, Thuy T Koll, Christina K Cramer
Journal of the National Cancer Institute. 2025-02-01
A multi-site feasibility study of a stepped-care telehealth intervention for depression and anxiety in post-treatment cancer survivors at community cancer clinics (WF-...
Suzanne C Danhauer, Gretchen A Brenes, Kathryn E Weaver, Emily V Dressler, Grace Westcott
Journal of Cancer Survivorship. 2025-01-14
Effectiveness of a Cardiovascular Health Electronic Health Record Application for Cancer Survivors in Community Oncology Practice: Results From WF-1804CD.
Kathryn E Weaver, Emily V Dressler, Heidi D Klepin, Simon C Lee, Brian J Wells
Journal of Clinical Oncology. 2025-01-01

Press Mentions

Study: Donepezil Does Not Improve Chemotherapy-Related Cognitive Impairment for Breast Cancer SurvivorsMay 20th, 2024
Cancer Researchers at Wake Forest Baptist Receive $25 Million from National Cancer InstituteSeptember 23rd, 2019
What Are the Symptoms of Glioblastoma? Brain Cancer Treatment, Survival RatesJuly 17th, 2019
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