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Gerald Shulman, MD, Endocrinology, New Haven, CT

GeraldIShulmanMDPhD, MACP, MACE, FRCP

Endocrinology • New Haven, CT

Diabetes, Lipid Metabolism

George R. Cowgill Professor of Medicine (Endocrinology) and Professor of Cellular & Molecular Physiology; Investigator Emeritus, Howard Hughes Medical Institute, Co-Director, Yale Diabetes Research Center

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  • Office

    789 Howard Ave
    Bldg
    New Haven, CT 06519
    Phone+1 203-737-1932
    Fax+1 203-785-3588

Summary

  • Dr. Gerald Shulman is a physician scientist and the George R. Cowgill Professor of Medicine and Cellular & Molecular Physiology at Yale School of Medicine and an Investigator Emeritus of the Howard Hughes Medical Institute. He received his medical degree from Wayne State University School of Medicine, and did his residency training in internal medicine at Duke University Medical Center and fellowship training in endocrinology/metabolism at the Mass General Hospital/Harvard Medical School. He has been in practice 38 years and specializes in diabetes and lipid metabolism.

Education & Training

  • Massachusetts General Hospital
    Massachusetts General HospitalResidency, Internal Medicine, 1981 - 1986
  • Duke University Hospital
    Duke University HospitalResidency, Internal Medicine, 1979 - 1981
  • Wayne State University School of Medicine
    Wayne State University School of MedicineClass of 1979

Certifications & Licensure

  • CT State Medical License
    CT State Medical License 1986 - 2025
  • American Board of Internal Medicine Internal Medicine
  • American Board of Internal Medicine Endocrinology, Diabetes and Metabolism

Awards, Honors, & Recognition

  • Elected Member National Academy of Sciences, 2007
  • Elected Member Institute of Medicine, 2005
  • Elected Member The American Society for Clinical Investigation, 1990
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Publications & Presentations

PubMed

Journal Articles

  • Metformin Inhibits Gluconeogenesis via a Redox-Dependent Mechanism in Vivo  
    Kitt F Petersen, Daniel F Vatner, Gerald I Shulman, Nature

Lectures

  • MR Imaging Glucose and Fat 
    ENDO 2018: 100th Endocrine Society Annual Meeting - Chicago, Illinios - 03/19/2018
  • An Extended-Release Mitochondrial Protonophore Reverses Nonalcoholic Fatty Liver Disease, Insulin Resistance, and Diabetes 
    New Haven, CT - 6/13/2014
  • Argininosuccinate Synthetase Regulates Hepatic AMPK Activity Linking Protein Catabolism and Ureagenesis to Hepatic Glucose Metabolism 
    New Haven, CT - 6/15/2014

Press Mentions

  • Fatty Liver Disease: The Process Behind the Benefit of Weight Loss Drugs
    Fatty Liver Disease: The Process Behind the Benefit of Weight Loss DrugsSeptember 17th, 2024
  • Meet Yale Internal Medicine: Mireille Serlie, MD, PhD, Professor of Medicine (Endocrinology)
    Meet Yale Internal Medicine: Mireille Serlie, MD, PhD, Professor of Medicine (Endocrinology)February 14th, 2023
  • Semglee Pen Recall; Prader-Willi Syndrome Drug Rejected; Resilience Good for Sex
    Semglee Pen Recall; Prader-Willi Syndrome Drug Rejected; Resilience Good for SexJanuary 24th, 2022
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Grant Support

  • Mechanisms Of Lipid-Induced Hepatic Insulin ResistanceNational Institute Of Diabetes And Digestive And Kidney Diseases2012
  • Cellular Mechanisms Of Insulin Resistance In HumansNational Institute Of Diabetes And Digestive And Kidney Diseases2000–2012
  • Genetic And Cellular Mechanisms Of Nafld And Hepatic Insulin ResistanceNational Institute Of Diabetes And Digestive And Kidney Diseases2010–2011
  • Mechanisms Of Fat Induced Insulin ResistanceNational Institute Of Diabetes And Digestive And Kidney Diseases2007–2011
  • Yale Mouse Metabolic Phenotyping CenterNational Institute Of Diabetes And Digestive And Kidney Diseases2001–2011
  • Role Of Mitochondrial Dysfunction In Insulin ResistanceNational Institute Of Diabetes And Digestive And Kidney Diseases2004–2008
  • Mitochrondrial Dysfunction: Role In Metabolic SyndromeNational Institute Of Diabetes And Digestive And Kidney Diseases2004–2008
  • Mechanisms Of Fatty Acid Induced Insulin ResistanceNational Institute Of Diabetes And Digestive And Kidney Diseases2003–2006
  • Liver Lipid And Carbohydrate Metabolism In Famial HypertriglyceridemiaNational Center For Research Resources2005
  • Differences Between Insulin Resistant And Non-Insulin Resistant IndividualsNational Center For Research Resources2005
  • Regulation Of UCP-3 Activity And Expression In MuscleNational Center For Research Resources2004–2005
  • Regulation Of Pathways Of Glycogen Repletion In Non, Pre, And Diabetic HumansNational Center For Research Resources2004
  • Regulation Of Brain Metabolite Synthesis By Ketones InNational Center For Research Resources2004
  • NMR Measurements Of Liver And Muscle Triglyceride Content In N/Ir StatesNational Center For Research Resources2004
  • Metabolic And Physiologic Differences Between Insulin Resistant And Non-InsulinNational Center For Research Resources2004
  • Metabolic And Endocrine Defects In Lean, Non-Diabetic Offspring Of NIDDM ParenNational Center For Research Resources2004
  • Fatty Liver /Hepatic Insulin Resistance From High Fat FENational Center For Research Resources2004
  • Effects Of FXR Activation On Hepatic Lipid And Carbohydrate MetabolismNational Center For Research Resources2004
  • Core--Clinical MetabolismNational Institute Of Diabetes And Digestive And Kidney Diseases1996–2002
  • In Vivo NMR Studies Of Carbohydrate MetabolismNational Institute Of Diabetes And Digestive And Kidney Diseases1989–2002
  • NMR Of Triglyceride Content Inmuscle In Insulin ResistanNational Center For Research Resources2000–2001
  • Metabolism/Physiology In Insulin&Noninsulin ResistantNational Center For Research Resources2000–2001
  • Epinephrine On Hepatic Glycogenolysis &GluconeogenesisNational Center For Research Resources2000–2001
  • Aspirin In Insulin Stimulated Carbohydrate MetabolismNational Center For Research Resources2000–2001
  • Quantitaion Of NET Hepatic Glycogenolysis And Gluconeogenesis With MetforminNational Center For Research Resources1998–2001
  • Hepatic Glucose Metabolism In IDDM (Type I) And NIDDM (Type Ii)National Center For Research Resources1998–2001
  • Cortical Glutamate, Glutamine &Gaba Levels In Hepatic EncephalopathyNational Center For Research Resources1998–2001
  • Mechanisms Of Insulin Resistance In Older PersonsNational Institute On Aging1997–2001
  • Metabolic And Endocrine Deficits In Lean Nondiabetic Offspring Of IDDM PatientsNational Center For Research Resources1997–2001
  • Mechanism Of Troglitazone Action In Type II Diabetes MellitusNational Center For Research Resources1997–2001
  • Regulation Of Pathways Of Glycogen Repletion In Prediabetics And DiabeticsNational Center For Research Resources1996–2001
  • Quantitation Of Hepatic Glycogenolysis And Gluconeogenesis During FastingNational Center For Research Resources1996–2001
  • Effects Of Fatty Acids On Muscle Glycogen SynthesisNational Center For Research Resources1996–2001
  • MRS Assessment Of Muscle Glycogen Utilization During Prolonged ExerciseNational Center For Research Resources1998–2000
  • Assessment Of Intracellular Free Glucose Consentration In Insulin ResistanceNational Center For Research Resources1998–2000
  • Core A--Clinical MetabolismNational Institute Of Diabetes And Digestive And Kidney Diseases1999
  • Effects Of Oral Fructose On Hepatic Glycogen Synthesis During Glucose IngestionNational Center For Research Resources1998–1999
  • Effects Of Glycogen Supercompensationon Insulin Sensitivity &Muscle GlycogenNational Center For Research Resources1998–1999
  • Effects Of Dietary Fat On Insulin Stimulated Muscle Glycogen SynthesisNational Center For Research Resources1998–1999
  • SIX Month, Double Blind Placebo Controlled, Multicenter Trial Of TroglitazonesNational Center For Research Resources1997–1999
  • NMR Studies Of Muscle Glycogen In Resting Subjects After Carbohydrate LoadingNational Center For Research Resources1997–1999
  • Human Amylin Analogue Ac137 VS Placebo On Hepatic Glucogen MetabolismNational Center For Research Resources1997–1999
  • Hepatic Gluconeogenesis In Normal, NIDDM, And Cirrhosis PatientsNational Center For Research Resources1996–1999
  • Epinephrine Effects On Muscle Glycogenolysis And Glycogen MetabolismNational Center For Research Resources1996–1999
  • Carbohydrate Metabolism In Supercompensated Muscle Using NMRNational Center For Research Resources1996–1999
  • NMR Studies Of Glycogen Metabolism In HumansNational Institute Of Diabetes And Digestive And Kidney Diseases1995–1999
  • Pharmacokinetics Of Bay27-9955National Center For Research Resources1998
  • Phase II Double Blind Placebo Controlled Multicenter Study Of TroglitazonesNational Center For Research Resources1996–1997
  • NMR Measurement Of Triglyceride In Insulin Resitant/Normal MuscleNational Center For Research Resources1996–1997
  • Human Amylin Analogue Ac137 VS Placebo On Hepatic Glucogen SynthesisNational Center For Research Resources1996–1997
  • Functional Imaging Of Ventromedial Hypothalmus In Normal, Diabetic,And Obese PTSNational Center For Research Resources1996–1997
  • Carbon 13 NMR Studies Of Liver And Muscle Glycogen TurnoverNational Center For Research Resources1996–1997
  • Pancreatic Insulin Secretion In Lean Offspring Of Parents With NIDDMNational Center For Research Resources1996
  • Intracellular Metabolism By Isotopes &Nmr SpectroscopyNational Institute Of Diabetes And Digestive And Kidney Diseases1987–1988
  • Intracellular Metabolism By Isotopes &Nmr SpectroscopyNational Institute Of Diabetes And Digestive And Kidney Diseases1986
  • Intracellular Metabolism By Isotopes &Nmr SpectroscopyNat Inst Of Arthritis, Diabetes, Digestive &Kidney Diseases1985

Professional Memberships

Dr. Gerald Shulman, Dr. Gerald Shulman, MD, Dr. G Shulman, Dr. Gerald I Shulman