GeorgeKarpouzasMDFACR

PubMed

• 3 citations
  Inflammation and immunomodulatory therapies influence the relationship between ATP-binding cassette A1 membrane transporter-mediated cholesterol efflux capacity and co...
  George A Karpouzas, Bianca Papotti, Sarah R Ormseth, Marcella Palumbo, Elizabeth Hernandez
  Journal of Translational Autoimmunity. 2023-12-01
• 7 citations
  Lipoprotein oxidation may underlie the paradoxical association of low cholesterol with coronary atherosclerotic risk in rheumatoid arthritis.
  George A Karpouzas, Sarah R Ormseth, Nicoletta Ronda, Elizabeth Hernandez, Matthew J Budoff
  Journal of Autoimmunity. 2022-05-01
• 2 citations
  Cardiovascular risk in vasculitis.
  Durga Prasanna Misra, Aman Sharma, George A Karpouzas, George D Kitas
  Best Practice & Research. Clinical Rheumatology. 2023-03-01

Journal Articles

• Highly sensitive cardiac troponin-I predicts occult coronary plaque burden, composition and cardiovascular events in patients with rheumatoid arthritis  
  Karpouzas GA, Estis J, Rezaeian P, Todd J, Budoff MJ, Rheumatology (Oxford), 1/1/2018
• Reply  
  Grossman JM, McMahon MA, Fitzgerald JD, Karpouzas GA, Chen W, Hahn BH, Merrill JT, Wallace DJ, Yazdany J, Ramsey-Goldman R, Arthritis Care Res (Hoboken), 1/1/2012
• Shortness of Breath and Hemoptysis in a 35-Year-Old Man with Extensive Perihilar Infiltrates  
  Jung C, Stringer W, Karpouzas GA, Chest, 1/1/2005
• Regulation of autoantibody production by multiple mechanisms in immune tolerance  
  Hahn BH, Ebling F, Singh RR, Singh RP, Dubey S, Kalsi J, Karpouzas GA, La Cava A, Autoimmunity Reviews, 1/1/2004
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Books/Book Chapters

• Dubois� Lupus Erythematosus and Related Syndromes 
  Chapter: Chapter 34, Hematologic and Lymphoid Manifestations in Systemic Lupus Erythematosus. 
  Page 426 - 438Karpouzas GAEditors: Wallace and Hahn.ElsevierEdition 8th,2013
• Dubois Lupus Erythematosus 
  Chapter: Chapter 51, The mother in lupus pregnancy. 
  Page 992 - 1039Karpouzas GA, Kitridou RCEditors: Wallace and Hahn.Edition 7th,2007
• Kelley�s Textbook of Rheumatology 
  Chapter: Pathogenesis of SLE 
  Tsao BP, Karpouzas GA, and Hahn BHEditors: Budd, R.C..W.B. Saunders Company, Philadelphia, PA2003
• Targeted Therapies in Rheumatology 
  Chapter: Chapter 34, Systemic Lupus Erythematosus: Targets for innovative therapies. 
  Page 563 - 582Karpouzas GA, Hahn, B.H.Editors: Smolen and Lipsky.2002
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Abstracts/Posters

• Predictors of Change in Coronary Plaque Burden and Composition in Patients with Rheumatoid Arthritis
  Karpouzas G, Ormseth S, Hernandez E, Budoff M, Arthritis Rheumatol, 1/1/2018
• Implications of Coronary Artery Calcium Score and Its Change over Time As Markers of Coronary Plaque Vulnerability and Patient Risk in Rheumatoid Arthritis
  Karpouzas G, Ormseth S, Hernandez E, Budoff M, Arthritis Rheumatol, 1/1/2018
• Impact of Inflammation and Biologic Treatments on Generation and Progression to Advanced Calcified Coronary Plaques in Rheumatoid Arthritis
  Karpouzas G, Ormseth S, Hernandez E, Budoff M, Arthritis Rheumatol, 1/1/2018
• Low Inflammatory Burden and Statin Exposure Inhibit Progression and Induce Regression of Early Coronary Plaques in Rheumatoid Arthritis
  Karpouzas G, Ormseth S, Hernandez E, Budoff M, Arthritis Rheumatol, 1/1/2018
• Does preconsult Electronic exchange affect postconsult diagnosis?
  Miller GD, Chou B, Karpouzas GA, EULAR, 1/1/2017
• Change in self-reported pain reflects psychological and functional state rather than inflammatory burden in United States Latinos with established Rheumatoid arthritis.
  Karpouzas GA, Hernandez E, Cost C, Ormseth SR, EULAR, 1/1/2017
• Effect Size Comparison of Ultrasound Measures in Rheumatoid Arthritis.
  Ranganath VK, Elashoff DA, Brook J, Ben-Artzi A, Navarro J, Tatosyan L, Karpouzas GA, Martin W, Kermani T, Choi S, Kaeley G, Arthritis Rheumatol, 1/1/2017
• Long-Term Effect of Sirukumab, an Anti�IL-6 Cytokine Monoclonal Antibody, on Radiographic Progression in Patients with Active Rheumatoid Arthritis Despite Disease-Modi...
  Karpouzas GA, Takeuchi T, Thorne C, Sheng S, Kurrasch R, Fei K, Hsu B, Arthritis Rheumatol, 1/1/2017
• Discordant Patient-Physician Assessments of Disease Activity and its Persistence Adversely Impact Quality of Life and Work Productivity in United States Hispanics with...
  Karpouzas GA, Ramadan S, Cost C, Draper T, Hernandez E, Ormseth SR, Arthritis Rheumatol, 1/1/2017
• A Cluster Analysis approach to Patient-Physician Discordance in Rheumatoid Arthritis Activity Evaluations optimally differentiates and predicts Clinical, Functional an...
  Karpouzas GA, Ormseth SR, Arthritis Rheumatol, 1/1/2017
• Occult coronary plaque presence and burden predict Cardiovascular Events in patients with Rheumatoid Arthritis.
  Karpouzas GA, Estis J, Todd J, Budoff MJ, Arthritis Rheumatol, 1/1/2017
• Highly Sensitive Cardiac Troponin-I in peripheral blood predicts Cardiovascular Events in patients with Rheumatoid Arthritis.
  Karpouzas GA, Estis J, Todd J, Budoff MJ, Arthritis Rheumatol, 1/1/2017
• Improvements in measures of work productivity/ interference and general health status with sirukumab treatment in patients with active RA and inadequate response to di...
  T. Takeuchi, G. Karpouzas, C. Thorne, K. McQuarrie, S. Sheng, W. Xu, S. Peterson, R. Ganguly, C. Han, K. Fei, B. Hsu, Ann Rheum Dis, 1/1/2016
• Analysis of a Phase 3 Study Evaluating the Efficacy of Sirukumab, an Anti-IL-6 Cytokine Monoclonal Antibody, Across Subgroups in Patients with Active Rheumatoid Arthri...
  Thorne C, Karpouzas G, Takeuchi T, Sheng S, Xu W, Rao R, Fei K, Hsu B, Arthritis Rheumatol, 1/1/2016
• Reliability and validity of the Patient-Health Questionnaire-9 for assessment of depression in disadvantaged Latinos with Rheumatoid arthritis living in the United Sta...
  Ormseth S, Draper T, Hernandez E, Karpouzas GA, Arthritis Rheumatol, 1/1/2016
• Rates and determinants of persistent Patient-Physician Discordance in global assessment of disease activity in Latinos with Rheumatoid arthritis in the United States.
  Karpouzas GA, Hernandez E, Cost C, Ormseth S, Arthritis Rheumatol, 1/1/2016
• Contribution of patient global assessment on loss and gain of disease remission in patients with established Rheumatoid arthritis in clinical practice.
  Karpouzas GA, Hernandez E, Cost C, Ormseth S, Arthritis Rheumatol, 1/1/2016
• Prediction of Inhibition of Radiographic Progression By Sirukumab, an Anti�IL-6 Cytokine Monoclonal Antibody, in Patients with Active Rheumatoid Arthritis Despite Dise...
  Karpouzas G, Takeuchi T, Thorne C, Sheng S, Li X, Rao R, Fei K, Hsu B, Arthritis Rheumatol, 1/1/2016
• Treatment with Sirukumab, an Anti-IL6 Cytokine Monoclonal Antibody, Improves Fatigue and Health-Related Physical and Emotional Well Being in Patients with Active Rheum...
  Clifton Bingham C, Tanaka Y, Karpouzas G, Takeuchi T, Aletaha D, Thorne C, Sheng S, Xu W, Rao R, Fei K, Hsu B, Agarwal P, Popik S, Kurrasch R, Peterson S, Ganguly R, H..., Arthritis Rheumatol, 1/1/2016
• Efficacy and safety of Sirukumab in patients with active RA despite disease modifying anti-rheumatic drug treatment: Results of a randomized, double blind, placebo con...
  T. Takeuchi, C. Thorne, G. Karpouzas, S. Sheng, W. Xu, R. Rao, K. Fei, B. Hsu, Ann Rheum Dis, 1/1/2016
• Anti-b2Glycoprotein-1 IgA antibodies independently and differentially contribute to thrombotic risk in systemic lupus erythematosus above and beyond ACL and LA: Lesson...
  T. Aung, G. Miller, S. Ormseth, R. Moran, G. Karpouzas, Ann Rheum Dis, 1/1/2016
• An analysis of laboratory results from 2 randomized, double-blind studies of sirukumab in patients with active RA refractory to disease modifying anti-rheumatic drug t...
  G. Karpouzas, C. Thorne, T. Takeuchi, Y. Tanaka, H. Yamanaka, M. Harigai, T. Ota, S. Sheng, W. Xu, S. Xu, R. Kurrasch, K. Fei, B. Hsu, Ann Rheum Dis, 1/1/2016
• Health-related physical and emotional well-being and fatigue improve significantly with sirukumab treatment: Results of a phase 3 study in patients with active RA refr...
  G. Karpouzas, C. Thorne, T. Takeuchi, K. McQuarrie, S. Sheng, W. Xu, S. Peterson, R. Ganguly, C. Han, K. Fei, B. Hsu, Ann Rheum Dis, 1/1/2016
• RA-specific cardiovascular risk calculators are not superior to risk calculators established for the general population: A validation analysis in a cohort of RA patien...
  C.S. Crowson, S.E. Gabriel, A.G. Semb, P.L. van Riel, G. Karpouzas, P.H. Dessein, C. Hitchon, V. Pascual Ramos, G.D. Kitas, Ann Rheum Dis, 1/1/2016
• Favorable effects of Silukumab treatment on physical function and reductions in morning stiffness in patients with active RA and inadequate response to disease modifyi...
  C. Thorne, T. Takeuchi, G. Karpouzas, K. McQuarrie, S. Sheng, W. Xu, S. Peterson, R. Ganguly, C. Han, K. Fei, B. Hsu, Ann Rheum Dis, 1/1/2016
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Lectures

• Clinical Manifestations of Rapid Disease Progression in Moderate to Severe Rheumatoid Arthritis 
  Multiple Locations, 2017, 2018 - 1/1/2018
• Accelerated coronary Atherogenesis and cardiovascular risk stratification in Rheumatoid Arthritis, 
  UCLA Medical Center, Westwood, CA, 2014, 2018; Harbor-UCLA Medical Center, Torrance, CA, 2017 - 1/1/2018
• A New Treatment Option for Adult Patients with Moderately to Severely Actively Rheumatoid Arthritis 
  Multiple Locations, 2017, 2018 - 1/1/2018
• Biomarkers and risk of Rheumatoid Arthritis 
  Seattle, WA, 2017; Mission Viejo, CA, 2017 - 1/1/2017
• Physician and patient reported outcomes in Latinos with RA: Longitudinal trends and determinants of change. 
  Multiple Locations, 2016, 2017 - 1/1/2017
• New developments in understanding the IL-6 pathway and its role in Rheumatoid Arthritis 
  Chicago, IL, 2017; Seattle, WA, 2018; Bellevue, WA, 2018 - 1/1/2017
• Role of Rheumatoid Factor in the Immune System. 
  Loma Linda University, Loma Linda CA, 2016; Los Angeles, CA, 2016; Costa Mesa, CA, 2016 - 1/1/2016
• Principles for safe utilization of biologic agents in systemic autoimmune disease 
  Harbor-UCLA Medical Center, Torrance, CA - 1/1/2016
• Immunology of pregnancy and challenges in systemic autoimmune disease 
  Harbor-UCLA Medical Center, Torrance, CA - 1/1/2016
• ANCA-Associated Vasculitis: Clinical Manifestations and Immunopathogenesis 
  Multiple Locations, 2014, 2015, 2016 - 1/1/2016
• Development and Amplification of Immune Response in Rheumatoid Arthritis. 
  Multiple Locations, 2015, 2016 - 1/1/2016
• Emergencies in Rheumatology 
  Multiple Locations, 2007, 2008, 2009, 2011, 2015, 2016 - 1/1/2016
• From Prognosis to Pathogenesis: The Role of Autoantibodies in Rheumatoid Arthritis. 
  Multiple Locations, 2016 - 1/1/2016
• Pulmonary Hypertension in Systemic Sclerosis 
  Harbor-UCLA Medical Center, Torrance, CA, 2016; UCLA Medical Center, Westwood, CA, 2016 - 1/1/2016
• Early initiation of Abatacept in moderate to severe RA: Clinical evidence for use of Abatacept in patients with early, rapidly progressing disease and poor prognosis 
  Seattle, WA - 1/1/2015
• Pathophysiology of Rheumatoid Arthritis: The Role of Effector Immune Cells 
  Seattle, WA, 2015; Kaiser Permanente, Orange County, CA, 2015 - 1/1/2015
• Generation and Amplification of autoimmune response in RA 
  UCLA Medical Center, Westwood, CA, 2015; LAC-USC Medical Center, Los Angeles, CA, 2015 - 1/1/2015
• The Role of Autoantibodies in Rheumatoid Arthritis. 
  Loma Linda University, Loma Linda CA - 1/1/2015
• Coronary atherosclerosis and cardiovascular risk stratification in Rheumatoid arthritis 
  Los Angeles, CA, 2014; Harbor-UCLA Medical Center, Torrance, CA, 2015; UCLA Medical Center, Westwood - 1/1/2015
• Management of Comorbidities in Rheumatoid Arthritis 
  UCLA Medical Center, Westwood, CA - 1/1/2015
• The many faces of Rheumatoid Arthritis 
  UCLA Medical Center, Westwood, CA - 1/1/2015
• Rheumatoid Arthritis Therapeutics debate: TNFi cycling vs. MOA switch in RA 
  Tucson, AZ - 1/1/2015
• Rheumatology Board Review for the Internist: A smorgasbord of delights 
  Harbor-UCLA Medical Center, Torrance, CA - 1/1/2014
• Evolution of (auto)immune response in Rheumatoid arthritis: the pivotal role of TNFa 
  1/1/2014
• Ustekinumab (IL-12/23) blockade in Psoriatic Arthritis 
  Multiple Locations, 2014 - 1/1/2014
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Other

• Rheumatology circles: Role of Golimumab in the treatment of moderate to severe Rheumatoid arthritis 
  Karpouzas GA, Janssen National Faculty series National WebEx
  1/1/2012
• Thesis: ANCA vasculitis in Greece 
  Karpouzas GA
  National and Kapodistrian University of Athens, School of Medicine, Zografou, Greece - 1/1/1995