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Office
1515 Holcombe Blvd,
Unit 442
Houston, TX 77030Phone+1 713-792-2736
Education & Training
- University of Texas M D Anderson Cancer CenterResidency, Neurosurgical Oncology, 1995 - 1996
- NYU Grossman School of MedicineResidency, Neurological Surgery, 1989 - 1995
- NYU Grossman School of MedicineInternship, Surgery, 1988 - 1989
- Yale School of MedicineClass of 1988
Certifications & Licensure
- FL State Medical License 2021 - Present
- AZ State Medical License 2024 - 2026
- TN State Medical License 2024 - 2026
- GA State Medical License 2024 - 2025
- LA State Medical License 2024 - 2025
- MS State Medical License 2024 - 2025
- OK State Medical License 2020 - 2025
- American Board of Neurological Surgery Neurological Surgery
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Awards, Honors, & Recognition
- Listed on Texas Super Doctors List Super Doctors, 2020-2021
- 2020 Annual Andrew Connor Curtis Endowed Featured Speaker Leonard M. Miller School of Medicine, University of Miami, 2020
- Otis W. and Pearl L. Walters Faculty Achievement Award in Clinical Research The University of Texas MD Anderson Cancer Center, 2019
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Clinical Trials
- Gene Therapy in Treating Patients With Recurrent Malignant Gliomas Start of enrollment: 1999 Feb 25
- Surgery Versus Stereotactic Radiosurgery in the Treatment of Single Brain Metastasis: A Randomized Trial Start of enrollment: 1998 Jan 01
- DNX-2401 (Formerly Known as Delta-24-RGD-4C) for Recurrent Malignant Gliomas Start of enrollment: 2009 Feb 01
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Publications & Presentations
PubMed
- 418 citationsPhase I Study of DNX-2401 (Delta-24-RGD) Oncolytic Adenovirus: Replication and Immunotherapeutic Effects in Recurrent Malignant Glioma.Frederick F. Lang, Charles A. Conrad, Candelaria Gomez-Manzano, W. K. Alfred Yung, Raymond Sawaya
Journal of Clinical Oncology. 2018-02-12 - 136 citationsInsulin and insulin-like growth factor II permit nerve growth factor binding and the neurite formation response in cultured human neuroblastoma cells.Esperanza Recio-Pinto, Frederick F. Lang, Douglas N. Ishii
Proceedings of the National Academy of Sciences of the United States of America. 1984-04-01 - 1628 citationsComprehensive and Integrative Genomic Characterization of Hepatocellular CarcinomaAdrian Ally, Miruna Balasundaram, Rebecca Carlsen, Eric Chuah, Amanda Clarke
Cell. 2017-06-15
Abstracts/Posters
- Predicting glioblastoma recurrence with hyperpolarized magnetic resonanceSalzillo T, Gumin J, Lee J, Millward NZ, Gammon ST, Lang FF, Bhattacharya P, World Molecular Imaging Congress 2021 Meeting, Miami, FL, 10/2021
- 4th Ventricle Subependymoma: To operate or not to operate?Haider AS, Ene C, Fuller GN, Schomer DF, Gule-Monroe MK, DeMonte F, Ferguson SD, Lang FF, McCutcheon I, Prabhu S, Raza SM, Suki D, Weinberg JS, Sawaya R, Congress of Neurological Surgeons Annual Meeting, Austin, TX, 10/2021
- Predictors of overall survival (OS) in patients (Pts) with melanoma brain metastasis (MBM) in the modern eraHasanov M, Milton DR, Davies A, Sirmans E, Saberian C, Posada E, Gershenwald JE, Torres-Cabala CA, Huse JT, Tawbi HA, Glitza IC, Li J, Chung C, Yeboa DN, Opusunju S, K..., American Society of Clinical Oncology, Virtual, 6/2021
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Lectures
- Biological Therapies for Brain Tumors: Oncolytic Viruses & Bone Marrow Stem Cells'NYU Langone Health Neurosurgery Grand Rounds, New York, NY - 10/2021
- Neurosurgical Management of Low Grade Gliomas: Insular Tumors26th Annual Meeting of the Japanese Congress for Brain Tumor Surgery, Virtual - 9/2021
- Biological Therapies for Gliomas: Viruses and Stem CellsThe University of Texas at Austin Dell Medical School Dept. of Neurosurgery Grand Rounds - 8/2021
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Press Mentions
- Intratumoral Viral Delivery Improves Glioblastoma SurvivalMay 17th, 2023
- Combined Delivery of Engineered Virus with Immunotherapy Is Safe and Improves Outcomes in Subset of Patients with GlioblastomaMay 15th, 2023
- Physician-Scientist Focused on Improving Brain Metastases TreatmentFebruary 17th, 2023
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Grant Support
- Systematic Dissection of Function and Mechanism of Long Non-Coding RNAs in GlioblastomaNIH/NCI2021–2026
- Glioma Therapy with Oncolytic Adenoviruses and Immunometabolic AdjuvantsNIH/NCI2021–2026
- New Therapeutic Approaches for Stratified High-REST GBM SubtypeNIH/NINDS2020–2025
- Determining the Optimal Ion and Fractionation Scheme for the Treatment of GBM in a Comprehensive Human Organoid ModelNIH/NCI2020–2025
- A Novel Adenoviral-Permissive, Immunocompetent Hamster Model to Evaluate Oncolytic Adenoviral Therapy for GlioblastomaNIH/NCI2020–2025
- Combating Breast Cancer Brain Metastasis by Blocking the Two-Pronged Driver Kinase Function of CDK5NIH/NCI2019–2024
- SPORE Director, Project 1 Co-Leader, CEP, DRP, Administrative Core, Pathology and Biorepository Core DirectorsNIH/NCI2013–2024
- Cancer Center Support Grant (CCSG) Brain Cancer ProgramNIH/NCI2013–2024
- Counteracting Space Radiation by Targeting Neurogenesis in a Human Brain Organoid ModelNational Aeronautics and Space Administration (Subcontract with Baylor College of Medicine)2020–2023
- MSC-Derived Exosomes and microRNA in Glioma TherapyNIH/NCI2017–2022
- Glioblastoma Moonshot: Longitudinal CSF and Blood Monitoring of Genomic Alterations in Patients & Phase I Clinical Trial of Delta-24-RGD Using BM-hMSCsThe University of Texas MD Anderson Cancer Center2014–2022
- CE: Animal CoreNational Cancer Institute2008–2011
- Bone Marrow Stem Cells: Novel Treatment Of Human GliomaNational Cancer Institute2006–2010
- Regulation Of P53-Mediated Apoptosis In GliomasNational Cancer Institute2003–2007
- Radiosensitization By Antiras Scfv-Expressing AdenovirusNational Cancer Institute2000
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