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Office
820 S Wood St
m/c 808
Chicago, IL 60612Phone+1 312-413-1984Fax+1 312-996-4238
Summary
- Dr. Frank González is a Professor of Obstetrics and Gynecology and a board certified Reproductive Endocrinologist at the University of Illinois at Chicago in Chicago, Illinois. He provides comprehensive care to couples with infertility and manages hormonal imbalances that affect menstrual function. Dr. González is an internationally recognized expert on Polycystic Ovary Syndrome (PCOS), the most common hormonal imbalance in reproductive age women.
Dr. González is a formally trained NIH-funded physician-scientist and his lab is an integral part of his translational research program. The González lab focuses on nutrient-induced inflammation in the development of key endocrine and metabolic abnormalities present in Polycystic Ovary Syndrome (PCOS); namely, ovarian dysfunction, insulin resistance, β-cell dysfunction and atherogenesis. Dr. González spearheads the focus by combining his clinical expertise in the care of women with PCOS, and his knowledge of clinical study design, endocrine and metabolic dynamic testing, and human subject recruitment with his formal training to oversee a basic research laboratory and troubleshoot basic research techniques. Dr. González designs translational studies that combine clinical research protocols for human subject interventions in a clinical research center setting with basic research techniques that evaluate inflammation at the molecular level in a laboratory setting. The overall aim is to provide clinical relevance to basic laboratory findings that bring innovation from the bench to the bedside.
Dr. González is a nine-time recipient of the “Star Award” for more than 10 years of contributions to research for the American Society for Reproductive Medicine, and is ranked in the top 0.23% of 26,440 published authors worldwide on PCOS by Expertscape.
Education & Training
- Case Western Reserve University/University Hospitals Cleveland Medical CenterFellowship, Reproductive Endocrinology and Infertility, 1987 - 1989
- Rochester General HospitalResidency, Obstetrics and Gynecology, 1983 - 1987
- Lewis Katz School of Medicine at Temple UniversityClass of 1983
- Harvard UniversityB.A, Biochemistry and Molecular Biology, 1975 - 1979
Certifications & Licensure
- IL State Medical License 2016 - 2026
- IN State Medical License 2010 - 2025
- MN State Medical License 2006 - 2025
- OH State Medical License 1987 - 2025
- NY State Medical License 1984 - 2001
- American Board of Obstetrics and Gynecology Obstetrics & Gynecology
- American Board of Obstetrics and Gynecology Reproductive Endocrinology/Infertility
Awards, Honors, & Recognition
- Castle Connolly Top Doctor Peer-nominated designation based on professional qualifications, education, hospital and faculty appointments, research leadership and professional reputation, 2022-2024
- Expertscape World Expert Ranked in the top 0.23% of 26,440 published authors worldwide on Polycystic Ovary Syndrome.
- Star Award American Society for Reproductive Medicine, Awarded to members for presenting during the annual meeting at postgraduate courses/seminars, scientific program symposia, oral and/or poster abstracts for at least nine of the previous ten years, 2013-2022
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Clinical Trials
- Evaluation of Oral Lipid Ingestion in Relation to Ovarian Androgen Secretion in Polycystic Ovary Syndrome (PCOS) Start of enrollment: 2012 Feb 01
- Treating Inflammation in Polycystic Ovary Syndrome to Ameliorate Ovarian Dysfunction Start of enrollment: 2018 Dec 05
Publications & Presentations
PubMed
- 341 citationsCirculating inflammatory markers in polycystic ovary syndrome: a systematic review and metaanalysisHéctor F. Escobar-Morreale, Manuel Luque-Ramírez, Frank González
Fertility and Sterility. 2011-03-01 - 27 citationsInflammation Triggered by Saturated Fat Ingestion Is Linked to Insulin Resistance and Hyperandrogenism in Polycystic Ovary SyndromeFrank J. Gonzalez, Robert V. Considine, Ola A Abdelhadi, Anthony J. Acton
The Journal of Clinical Endocrinology and Metabolism. 2020-06-01 - 121 citationsThe HNF-1 target Collectrin controls insulin exocytosis by SNARE complex formationKenji Fukui, Qin Yang, Yang Cao, Noriko Takahashi, Hiroyasu Hatakeyama
Cell Metabolism. 2005-12-01
Journal Articles
- Adrenal involvement in polycystic ovary syndrome.González F, Sem Reprod Endocrinol 1997, 15:137-157.
- Adrenal morphologic considerations in polycystic ovary syndrome.González F, Speroff L, Obstet Gynecol Survey 1990, 45:491-508
- Adrenal and ovarian steroid hormone responses to gonadotropin releasing hormone agonist treatment in women with polycystic ovary syndrome.González F, Hatala DA, Speroff L, Am J Obstet Gynecol 1991, 195:535-545
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Books/Book Chapters
Abstracts/Posters
- Androgen administration induces the expression of NFkB, TNFalpha and IL-1beta in mononuclear cells of normal reproductive-age women.González F, Daniels JK, Schimke JM, Nair KS, 8th meeting of the Androgen Excess and Polycystic Ovary Syndrome Society, Program pg 31, Munich, Germany
- Insulin sensitivity and hyperandrogenism in polycystic ovary syndrome are related to activated nuclear factor KB from mononuclear cells in the fasting stateGonzález F, Rote NS, Minium J, Kirwan JP, 89th meeting of the Endocrine Society, Program pg 142, Toronto, Ontario, Canada
- HDL cholesterol is a strong predictor of insulin resistance in older Caucasian adults.Yassine H, Marchetti CM, Brooks LM, Krishnan RK, González F, Kirwan JP, 67th Scientific Sessions of the American Diabetes Association, Diabetes 56 (2 Suppl):A626, Chicago, IL
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Lectures
- Surgical Management of Obesity to Ameliorate Metabolic Syndrome in Polycystic Ovary Syndrome.64th Annual Meeting of the American Society for Reproductive Medicine, San Francisco, CA
- Hyperglycemia-Induced Oxidative Stress and TNF alpha Release in Polycystic Ovary Syndrome.University Hospitals of Cleveland, Dept. of Ob-Gyn, Research Seminar, Cleveland, OH
- The Role of Nutrition in the Management of Polycystic Ovary Syndrome.MetroHealth Medical Center, Dept. of Nutrition, Annual Nutrition Seminar for Dietitians, Cleveland
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Press Mentions
- Research Study – Do You Have PCOS?August 26th, 2019
- Does Chronic Inflammation Contribute to PCOS?October 10th, 2017
- Detailed AgendaMarch 15th, 2016
Grant Support
- Reproductive Medicine Collaborative Consortium: A Randomized Placebo-Controlled Trial of EGCG to Improve Fertility in Women with Uterine FibroidsNational Institutes of Health2019–2024
- Treating Inflammation to Ameliorate Ovarian Dysfunction in PCOSNational Institutes of Health2016–2024
- Inflammation: Effect on Insulin Resistance in PCOSNational Institutes of Health2006–2010
Professional Memberships
- American College of Obstetricians and Gynecologists - ACOGFellow
- Fellow
- American Society for Reproductive Medicine - ASRMMember
- Society for Reproductive Investigation - SRIMember
- The Endocrine Society - ENDOMember
- Androgen Excess and PCOS Society - AE-PCOSMember
- American Association of Gynecologic Laparoscopists - AAGLMember
- Society for Reproductive Endocrinology and Infertility - SREIMember
- Society of Reproductive Surgeons - SRSMember
Other Languages
- Spanish
External Links
- UIC Faculty Webpagehttps://chicago.medicine.uic.edu/departments/academic-departments/obstetrics-and-gynecology/obgyn-faculty/frank-gonzalez/
- Google Scholarhttp://scholar.google.com/citations?hl=en&user=-OkrP3sAAAAJ
- Research Gatehttps://www.researchgate.net/profile/Frank_Gonzalez4
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