FrancisJ.GilesMD

Oncology • San Antonio, TX

Hematologic Oncology

NMDTI

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Office
7979 Wurzbach Rd
San Antonio, TX 78229
Phone+1 210-450-1000

Fax+1 210-450-1150

Education & Training

National University of Ireland, GalwayClass of 1982

Certifications & Licensure

CA State Medical License 1997 - 2025
TX State Medical License 1998 - 2025
IL State Medical License 2013 - 2023
Royal College of PathologyHematology

Clinical Trials

6-Hydroxymethylacylfulvene in Treating Patients With Refractory Myelodysplastic Syndrome, Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, or Blastic Phase Chronic Myelogenous Leukemia Start of enrollment: 1999 Jul 01
Completed
Phase 1
Liposomal Daunorubicin and SU5416 in Treating Patients With Hematologic Cancer That Has Not Responded to Initial Therapy Start of enrollment: 2000 Mar 01
Completed
Phase 1, Phase 2
Troxacitabine in Treating Patients With Chronic Myelogenous Leukemia Start of enrollment: 2000 Dec 11
Completed
Phase 2
Study of ABT-751 in Patients With Refractory Hematologic Malignancies Start of enrollment: 2002 Dec 01
Completed
Phase 1
RAD001 in Relapsed or Refractory AML, ALL, CML in Blastic-Phase, Agnogenic Myeloid Metaplasia, CLL, T-Cell Leukemia, or Mantle Cell Lymphoma Start of enrollment: 2004 Apr 01
Completed
Phase 1, Phase 2
VNP40101M in Treating Patients With Acute Myelogenous Leukemia or High-Risk Myelodysplasia Start of enrollment: 2005 Nov 01
Completed
Phase 2
CCI-779 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndromes, or Chronic Myelogenous Leukemia in Blastic Phase Start of enrollment: 2004 Apr 01
Completed
Phase 2
CCI-779 in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia Start of enrollment: 2004 May 01
Terminated
Phase 2
Rebeccamycin Analog in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, Acute Lymphoblastic Leukemia, or Chronic Myelogenous Leukemia Start of enrollment: 2004 May 01
Completed
Phase 1
XK469R in Treating Patients With Refractory Hematologic Cancer Start of enrollment: 2004 Oct 01
Completed
Phase 1
Study for Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) Start of enrollment: 2005 Jul 01
Terminated
Phase 2
Phase I/II Trial of VELCADE Plus Zevalin in Patients With Relapsed or Refractory Follicular Lymphoma Start of enrollment: 2007 Jul 24
Terminated
Phase 1, Phase 2
A Phase I/II Study of CP-4055 in Patients With Refractory/Relapsed Hematologic Malignancies Start of enrollment: 2006 May 01
Completed
Phase 1, Phase 2
Nilotinib in Treating Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia Start of enrollment: 2008 Oct 01
Completed
Phase 2
Hydroxychloroquine + Vorinostat in Advanced Solid Tumors Start of enrollment: 2009 Nov 01
Completed
Phase 1
Study of Elacytarabine Versus Investigator's Choice in Patients With Late Stage Acute Myeloid Leukaemia (AML) Start of enrollment: 2010 Jun 01
Completed
Phase 3
NU-0129 in Treating Patients With Recurrent Glioblastoma or Gliosarcoma Undergoing Surgery Start of enrollment: 2017 May 25
Completed
Early Phase 1
9-ING-41 in Patients With Advanced Cancers Start of enrollment: 2019 Jan 04
Active, not recruiting
Phase 2
Actuate 1901: 9-ING-41 in Myelofibrosis Start of enrollment: 2020 Aug 20
Completed
Phase 2
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Publications & Presentations

PubMed

217 citations
Clinical Outcomes and Prognostic Factors in Patients With Richter's Syndrome Treated With Chemotherapy or Chemoimmunotherapy With or Without Stem-Cell Transplantation
Apostolia Maria Tsimberidou, Susan O'Brien, Issa F. Khouri, Francis J. Giles, Hagop M. Kantarjian
Journal of Clinical Oncology. 2006-05-20
98 citations
Fractionated cyclophosphamide, vincristine, liposomal daunorubicin, and dexamethasone plus rituximab and granulocyte‐macrophage–colony stimulating factor (GM‐CSF) alte...
Apostolia M. Tsimberidou, Hagop Kantarjian, Jorge Cortes, Deborah A. Thomas, Stefan Faderl
Cancer. 2003-04-01
65 citations
Nilotinib population pharmacokinetics and exposure-response analysis in patients with imatinib-resistant or -intolerant chronic myeloid leukemia
Francis J. Giles, Ophelia Q. P. Yin, William M. Sallas, Philipp le Coutre, Richard C. Woodman
European Journal of Clinical Pharmacology. 2013-04-01

Abstracts/Posters

Maintenance of Health-Related Quality of Life in the Phase 4 BYOND Study of Bosutinib for Pretreated Chronic Phase Chronic Myeloid Leukemia
Frank Giles, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
Efficacy of Bosutinib in Imatinib-Resistant Vs Dasatinib/Nilotinib-Resistant Chronic Phase Chronic Myeloid Leukemia: Results from the Phase 4 BYOND Study
Frank Giles, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
Moxetumomab Pasudotox-Tdfk in Heavily Pretreated Patients with Relapsed/Refractory Hairy Cell Leukemia (HCL): Long-Term Follow-up from the Pivotal Phase 3 Trial
Francis J. Giles, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
Efficacy of Bosutinib in Imatinib-Resistant Vs Dasatinib/Nilotinib-Resistant Chronic Phase Chronic Myeloid Leukemia: Results from the Phase 4 BYOND Study
Frank Giles, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
Analyses of Predictors of Durable Treatment-Free Remission in Patients with Chronic Myeloid Leukemia in Chronic Phase Following Frontline or Second-Line Nilotinib
Francis J. Giles, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
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Lectures

Treatment-free remission (TFR) following frontline (1L) nilotinib (NIL) in patients (pts) with chronic myeloid leukemia in chronic phase (CML-CP): 192-week data from t...
2019 ASCO Annual Meeting - 6/1/2019

Press Mentions

$Moxetumomab Pasudotox in Heavily Pre-Treated Patients with relapsed/refractory Hairy Cell Leukemia (HCL): Long-Term Follow-up from the Pivotal Trial$
Moxetumomab Pasudotox in Heavily Pre-Treated Patients with relapsed/refractory Hairy Cell Leukemia (HCL): Long-Term Follow-up from the Pivotal TrialFebruary 24th, 2021
9-ING-41, a Small Molecule Inhibitor of GSK-3beta, Potentiates the Effects of Anticancer Therapeutics in Bladder CancerDecember 27th, 2019
Estudio Descubre Nueva Manera De Hacer Más Eficaz a La Quimioterapia Contra El Cáncer PancreáticoSeptember 25th, 2019
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FrancisJ.GilesMD

Dr. Giles is on Doximity

Education & Training

Certifications & Licensure

Clinical Trials

Publications & Presentations

Press Mentions

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