FloydElliottBloomMD

Psychiatry • La Jolla, CA

Addiction, Neuropsychiatry, Psychopharmacology

Professor Emeritus, The Scripps Research Institute

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Office
10666 N Torrey Pines Rd
La Jolla, CA 92037
Phone+1 858-784-9730

Fax+1 858-784-8851

Education & Training

USPHS SpecialPost-Doctoral Fellowship, 1964 - 1966
Washington University/B-JH/SLCH ConsortiumResidency, Internal Medicine, 1960 - 1962
Washington University in St. Louis School of MedicineClass of 1960
Southern Methodist UniversityA.B, cum laude, 1956

Awards, Honors, & Recognition

Briggs Lecture Univ. Texas Health Science Center, San Antonio, 2010
Packard Memorial Lecture Uniform Services University of Health Sciences, 2010
Morell Lecture Rush University Medical School, 2009
Mysell Lecture Harvard Medical School, 2009
Chairman, Lashley Awards Committee American Philosophical Society, 2001, 2008, 2008
Co-Chairman Report Review Committee, NAS, 2004, 2008, 2008
J. Edward Berk Lecture Medal University California-Irvine, 2007
Rhoda and Bernard Sarnat International Prize in Mental Health Institute of Medicine, 2005
Southern Methodist University Distinguished Graduate Medal Dedman College, 2005
Senior Affliated Research Fellow The Neurosciences Institute, 2004
Walsh McDermott Medal Institute of Medicine, 2004
Honorary Member The American Neurological Association, 2004
Thomas William Salmon Medal for Psychiatry and Mental Hygiene New York Academy of Medicine, 2004
Erlanger Gasser Lecture Washington University, 2000
Council of Biology Editors Award for Meritorious Achievement 1999
Doctor of Science Washington University, 1998
Nathan R. Brewer Scientic Achievement Award American Association for Laboratory Animal Science, Cincinnati, Ohio, 1998
ACNP Hoch Award 1998
Board of Trustees Washington University, 1998
Gold Medal Award Society of Biological Psychiatry, 1997
Honorary Doctor of Science Thomas Jefferson Univ, 1997
Laquer Lecture Netherlands Brain Research Institute and Dutch Society for Endocrinology, 1997
Doctor of Science honoris causa, Mt. Sinai Sch of Med.NY, 1996
Golgi Medal University of Brescia, Italy, 1996
Invited Lecturer 3rd Princeton Conf. Drug Development, 1995
Lectura Magistralis Sardinia, Italy, 1995
Brookhart Lecturer University of Oregon, 1994
Ripley Lecturer Univ of Washington, 1994
Recipient Pythagora Prize, Rome, 1994
American Philosophical Society Invited Lecturer 1994
Decade of the Brain Lecturer Society for Neuroscience, 1994
Distinguished Research Award Soc of Addiction Medicine, 1993
First David Lester Lecturer Rutgers University, 1993
Salmon Lecturer New York State Psychiatric Society, 1991
Ninth annual Hermann von Helmholtz Award 1990
Chairman Institute of Medicine Committee on Policies for the Allocation of Resources for Biomedical Research, 1988, 1990, 1990
Secretary Class II National Academy of Sciences, 1986, 1989, 1989
Pasarow Award in Neuropsychiatry 1989
Janssen Award in Basic Sciences 1989
Erspamer Lecture FIDIA Inst. Neuroscience, Georgetown Univ., 1989
Board of Directors, Am Association for the Advancement of Science, 1985,1989, 1989
Member Scienti?c Advisory Board, Fondation pour l'etude du Systeme Nerveux Central et Peripherique, 1982, 1989, 1989
Foreign Member Royal Swedish Academy of Sciences, 1989
Co-Chairman Gordon Conference on Peptides, 1988
First John D. DeLuca Lecturer National Library of Medicine, 1988
George Klenk Lecturer and Medalist University of Cologne, 1987
Albert Dorfman Lecture University of Chicago, 1987
Distinguished Fellow American Psychiatric Association, 1986
Member Richard Lounsbery Award Jury, NAS, 1979, 1981, 1986, 1986
Chairman Neurobiology Section, NAS, 1979, 1983, 1985, 1986, 1986
Steven C. Beering Award for Advancement in Medical Science Indiana University School of Medicine, 1985
Doctor of Science hon. caus., Hahnemann Univ., Philadelphia, 1985
Doctor of Science hon. caus., Univ. of Rochester, New York, 1985
Fourth Marjorie Guthrie Lecture in Genetics NIH, 1984
Wellcome Visiting Professor Royal Society of Medicine, 1984
Doctor of Science hon. caus., Southern Methodist University, 1983
National Inst.Alcohol Abuse and Alcoholism Research Planning Panel 1983
Elected Member Institute of Medicine, 1982
Member NAS Institute of Medicine, 1982
Study Chairman National Academy of Sciences Third Five Year Outlook Report on Science and Technology, 1982
Adjunct Professor Step VIII Departments of Pharmacology and Psychiatry, University of California, Coll. Medicine, Irvine, 1982
Paul Lamson Lecture Recipient Vanderbilt University, 1982
The Harold Cummins Memorial Lectureship Recipient 1981
Member National Commission on Alcoholism and Other Alcohol Related Problems, 1980
Distinguished Alumnus Washington University, 1980
National Assoc. of Mental Health McAlpin 1980
Member National Advisory Mental Health Council, 1976, 1980, 1980
Visiting Professor College de France, 1979
Elected Member The American Society for Clinical Investigation, 1978
Member Research Work Grp, President's Commission on Mental Health, 1977
Member National Academy of Sciences, 1977
Adjunct Professor Department of Neurosciences and Department of Psychiatry, University of California, San Diego, 1977
Biological Sciences Washington Academy of Arts and Sciences, 1974
Mathilde Solowey 1973
Arthur S. Flemming 1972
A. Cressy Morrison 1971
A. E. Bennett 1971
Member Alan T. Waterman Award Committee, NSF, 1978, 1980, 1960
Whos Who in Medicine and Healthcare Marquis Whos Who
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Publications & Presentations

PubMed

100 citations
Rewarding properties of β-endorphin as measured by conditioned place preference
Marianne Amalric, E J Cline, Joe L. Martinez, Floyd E. Bloom, George F. Koob
Psychopharmacology. 1987-01-01
105 citations
Neurological abnormalities associated with feline immunodeficiency virus infection.
Tom R. Phillips, Oscar Prospéro-García, D. L. Puaoi, Danica L. Lerner, Howard S. Fox
The Journal of General Virology. 1994-05-01
1376 citations
Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle
Gary Aston-Jones, Floyd E. Bloom
The Journal of Neuroscience. 1981-08-01

Journal Articles

Kinetics of the negative afterpotential in frog single nerve ?bers.
Schoepf1e, G.M., Bloom, F.E., and Hellam, D., Am. J. Physiol.
Effects of cyanide and dinitrophenol on membrane properties of single nerve ?bers.
Schoep?e, G.M. and Bloom, F.E., Am. J. Physiol.
Studies on the kinetics of procaine-acetylcholine antagonism.
Bloom, F.E., Honors Thesis, Washington Univ. Sch. Med.
Kinetics of procaine-acetylcholine antagonism.
Bloom, F.E. and Schoep?e, G.M., Am. J. Physiol.
Response of individual rabbit olfactory nerve cells to microelectrophoretically administered chemical substances.
Baumgarten, R. von, Bloom, F.E., Oliver, A.P., and Salmoiraghi, G.C, P?ugers Archiv.
Microelectrophoretic studies on adrenergic mechanisms of rabbit olfactory bulb neurons.
Bloom, F.E., Baumgarten, R. von, Oliver, A.P., Costa, E., and Salmoiraghi, G. C, Life Sciences
Analysis of individual rabbit olfactory bulb neuron response to microelectrophoresis of acetylcholine, norepinephrine and serotonin synergists and antagonists.
Bloom, F.E., Costa, E., and Salmoiraghi, and G.C., Pharmacol
Adrenergic mechanisms in rabbit olfactory bulb.
Salmoiraghi, G.C., Costa, E., and Bloom, F.E., Am. J. Physiol.
Anesthesia and the responsiveness of individual neurons of the cat's caudate nucleus to acetylcholine, norepinephrine, and dopamine administered by microelectrophore...
Bloom, F.E., Costa, E., and Salmoiraghi, and and G.C, Pharmacol
Fine structural localization of noradrenaline in nerve ending vesicles of the autonomic nervous system.
Bloom, F.E. and Barrnett, R.J., Nature
Fine structural localization of acetylcholinesterase in the electroplaque of the electric eel.
Bloom, F.E. and Barrnett, R.J, J. Cell Biol.
Histochemical and functional relationships of catecholamines in adrenergic nerve endings: I. Participation of granular vesicles.
Van Orden, L.S., Bloom, F.E., Barrnett, R.J., and Giarman, N.J, Pharmacol
Electron-microscopic autoradiography of rat hypothalamus after intraventricular 3H- norepinephrine.
Aghajanian, G.K. and Bloom, F.E, Science
The uptake of 5-hydroxytryptamine from the cerebral ventricles: autoradiographic localization. Biochem.
Aghajanian, G.K., Bloom, F.E., Lovell, R.A., Sheard, M.H., and Freedman, D. X., Pharmacol
Cytochemistry of synapses: selective staining for electron microscopy.
Bloom, F.E. and Aghajanian, G.K., Science
Localization of tritiated serotonin in rat brain by electron microscopic autoradiography.
Aghajanian, G.K. and Bloom, F.E, Pharmacol
The failure of magnesium pemoline to affect RNA synthesis in brain.
Morris, N.R., Aghajanian, G.K., and Bloom, F.E., Science
Electron microscopic localization of 3H-norepinephrine in rat brain by electron microscopic autoradiography: effect of drugs.
Aghajanian, G.K. and Bloom, F.E, Pharmacol
The formation of synaptic junctions in developing rat brain: A quantitative electron microscopic study.
Aghajanian, G.K. and Bloom, F.E., Brain Res
An electron microscopic analysis of large granular synaptic vesicles of the brain in relation to monoamine content.
Bloom, F.E. and Aghajanian, G.K., Pharmacol
Fine structural and cytochemical analysis of the staining of synaptic junctions with phosphotungstic acid.
Bloom, F.E. and Aghajanian, and G.K., Ultr. Res
Light and heavy norepinephrine storage particles in the rat heart and in bovine splenic nerve.
Roth, R.H., Stjarne, L., Bloom, F.E., and Giarman, N.J., Pharmacol
An osmiophilic substance in brain synaptic vesicles not related to catecholamine content.
Bloom, F.E. and Aghajanian, G.K., Experientia
Lack of concentrating mechanism for norepinephrine in sympathetic nerve trunk.
Stjarne, L., Roth, R.H., Bloom, F.E., and Giarman, N.J., Pharmacol
Fine structural demonstration of nerve degeneration in the suprachiasmatic nucleus of the rat after lesions in raphe nuclei.
Aghajanian, G.K., Bloom, F.E., and Sheard, and M.H., Brain Res
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Books/Book Chapters

The Dana Alliance’s 2009 Progress Report on Brain Research.
Bloom, F.E. Coyle, JEditors: Choi,D..
Annals of the NY Academy of Sciences: Cocaine, effects on the Developing Brain
Chapter: Keynote Address
Bloom, F.E.Editors: J.A. Harvey and B.E. Kosofsky.
Fundamental Neuroscience.
Zigmond, M.J., Bloom, F.E., Landis, S.C., Roberts, J.L. and Squire, L.R.Academic Press, New York
Brain, Mind and Behavior.
Bloom, F., Nelson, C.A., Lazerson, A.Worth Publishers, New YorkEdition 3rd,
Fundamental Neuroscience.
Squire, L.R., Bloom, F.E., McConnell, S.K., Roberts, J.L., Spitzer, N.C., and Zigmond, M.JElsevier ScienceEdition 2nd,
The Biochemical Basis of Neuropharmacology.
Cooper, J.R., Bloom, F.E. and Roth, R.H.Oxford University PressEdition 8th,
The Dana Guide to Brain Health.
Bloom, F.E., Beal, M.F. and Kupfer, D.JThe Dana Press , New York
The Dana Guide to Brain Health.
Bloom, F.E., Beal, M.F. and Kupfer, D.J.The Dana Press , New YorkEdition 2nd,
The Best of the Brain from Scientific American.
Bloom and FEEditors: Bloom, FE.The Dana Press
Introduction to Neuropsychopharmacology.
Iversen, L.L., Iversen, S.D., Bloom, F.E., and Roth, R.H.Oxford University Press, New York
Progress in Brain Research.
Chapter: Neuroscience: From the Molecular to the Cognitive
Bloom, F.E.Elsevier Science Publishers, Amsterdam
Opportunities in Neuroscience for Future Army Applications.
Bloom and F.ENational Academy Press
Psychopharmacology: A Generation of Progress.
Chapter: Central noradrenergic systems: Physiology and Pharmacology.
Page 131 - 141Bloom, F.E., M.A. Lipton, A. DiMascioEditors: K.F. Killam.Raven Press, New York
Neural Peptides and Neuronal Communication.
Chapter: Oral loading with l- tryptophan may augment the simultaneous release of ACTH and beta-endorphin that accompanies periaqueductal stimulation in humans.
Page 563 - 570Hosobuchi, Y., Rossier, J. and Bloom, F.E.Editors: E. Costa and M. Trabucchi.Raven Press
Brain Mechanisms of Perceptual Awareness and Purposeful Behavior.
Chapter: Modulation of unit activity by chemically coded neurons
Page 431 - 448Siggins, G.R. and Bloom, F.E.Editors: O. Pompeiano and C.A. Marsan.Raven Press, New York
Molecular Biology of the Human Brain.
Chapter: Neuronal diversity in the mammalian brain: Molecular biological approaches.
Page 13 - 26Bloom, F.E., Milner, R.J., Sutcliffe, J.G., Morrison, J.H., Travis, G.H. and Miller, F.D.Editors: E.G. Jones, Alan R. Liss..Inc., New York
The Biochemical Basis of Neuropharmacology.
Cooper, J.C., Bloom, F.E., and Roth, R.H.Oxford Univ. Press, New YorkEdition 1th,
The Biochemical Basis of Neuropharmacology.
Cooper, J.R., Bloom, F.E.and Roth, R.H.Oxford University PressEdition 5th,
Handbook of Physiology, Section I: The Nervous System.
Chapter: Intrinsic Regulatory Systems of the Brain.
Bloom and F.EAmerican Physiological Society, Bethesda, MD
Neurosciences Research Program Bulletin.
Chapter: Amino Acids and Polypeptides in Neuronal Function
Page 122 - 251Bloom and F.E
Funding Health Sciences Research: A Strategy to Restore Balance.
Bloom, F.E. and Randolph, M.A.National Academy Press, Washington, D.C.
The Biochemical Basis of Neuropharmacology.
Cooper, J.R., Bloom, F.E.and Roth, R.H.Oxford University PressEdition 6th,
Psychopharmacology: The Fourth Generation of Progress.
Bloom, F.E. and Kupfer, D.J.Raven Press, Ltd., New York
The Biochemical Basis of Neuropharmacology.
Cooper, J.R., Bloom, F.E. and Roth, and R.H.Oxford University PressEdition 7th,
Neuromethods.
Chapter: Apoptosis Techniques and Protocols.
Geiger, K., Bloom, F.E. and Sarvetnick, NEditors: A.A. Boulton, G.B. Baker, and Judes Poirier.The Humana Press, Inc.
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Press Mentions

Joe L. Martinez Jr. (1944–2020)October 16th, 2020
Torgny Svensson, a Superb Mind and an Inspiring ColleagueSeptember 10th, 2020
Leslie L. Iversen, Ph.D., (1937–2020)August 19th, 2020
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Grant Support

Computer-Assisted Stereology For Mouse Brain DatabaseNational Institute Of Mental Health1999–2000
Core-VivariumNational Institute Of Mental Health1996–2000
Core--Cell CultureNational Institute Of Mental Health1996–2000
AIDS Dementia--Molecular And Cellular MechanismsNational Institute Of Mental Health1994–2000
Computer Assisted Stereology For Mouse Brain DatabasesNational Institute Of Mental Health1997
Pilot ComponentNational Institute On Alcohol Abuse And Alcoholism1996–1997
Neuronal Vulnerability And Informatics In Human DiseaseNational Institute Of Mental Health1994–1997
Neuropsychopharmacology - Multidisciplinary TrainingNational Institute On Alcohol Abuse And Alcoholism1992–1996
CNS Effects Of Alcohol--Cellular NeurobiologyNational Institute On Alcohol Abuse And Alcoholism1993–1995
Cellular Mechanisms In AIDS DementiaNational Institute Of Mental Health1994
Neuronal Vulnerability And Informatics In Human DiseaseNational Institute Of Mental Health1993–1994
Scientific And Technical Evaluation AwardNational Institute Of Mental Health1992–1994
CNS Effects Of Alcohol: Cellular NeurobiologyNational Institute On Alcohol Abuse And Alcoholism1990–1993
Molecular Characterization Of Neuronal SpecificityNational Institute Of Neurological Disorders And Stroke1990–1993
AIDS Dementia: Molecular And Cellular MechanismsNational Institute Of Mental Health1990–1993
Small Instrumentation GrantNational Institute On Alcohol Abuse And Alcoholism1991
Neuropsychopharmacology - MultidisciplinaryNational Institute On Alcohol Abuse And Alcoholism1989–1991
Asip-Scripps Clinic And Research FoundationNational Institute On Alcohol Abuse And Alcoholism1990
Molecular Characterization Of Neuronal SpecificityNational Institute Of Neurological Disorders And Stroke1986–1989
Core--Peptide Biology LaboratoryNational Institute On Alcohol Abuse And Alcoholism1985–1989
Core--Computer FacilityNational Institute On Alcohol Abuse And Alcoholism1985–1989
Core--Chronic Alcohol Administration ModelNational Institute On Alcohol Abuse And Alcoholism1985–1989
CNS Effects Of Alcohol: Cellular NeurobiologyNational Institute On Alcohol Abuse And Alcoholism1985–1989
Neuropsychopharmacology - MultidisciplinaryNational Institute On Alcohol Abuse And Alcoholism1987–1988
CNS Effects Of Alcohol: Cellular NeurobiologyNational Institute On Alcohol Abuse And Alcoholism1986–1987
Neuropsychopharmacology-MultidisciplinaryNational Institute On Alcohol Abuse And Alcoholism1985–1986

Other Languages

French, German