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Office
400 Parnassus Ave
# A808
San Francisco, CA 94143Phone+1 415-353-7500Fax+1 415-353-2889
Summary
- Dr. Ethan Winkler is a dual fellowship-trained cerebrovascular neurosurgeon who provides comprehensive endovascular and open microsurgical care for vascular disorders of the brain, neck or spine. These conditions include brain aneurysms, arteriovenous malformations, cavernous malformations, arteriovenous fistulas, Moyamoya disease, stroke, and carotid artery disease. Dr. Winkler's research focuses on understanding the biological basis of debilitating diseases that result in stroke with an emphasis on vascular malformations and aneurysms. He leads the Vascular Anomalies & Stroke Computation (VASC) Laboratory at UCSF. The lab brings together genomic, stem cell, and bioengineering technologies to understand the cell-specific genetic mechanisms that regulate the brain's vasculature in health and disease. To translate these findings back to the clinic, we are also developing new technologies, such as endovascular biopsy, to inform and to develop new, state-of-the-art precision therapeutics to reverse cerebrovascular pathology.
Education & Training
- Barrow Neurological Institute at St Joseph's Hospital and Medical CenterFellowship, Cerebrovascular & Skull Base Surgery, 2022 - 2023
- Barrow Neurological Institute at St Joseph's Hospital and Medical CenterFellowship, Neuroendovascular Intervention (Neurological Surgery), 2021 - 2022
- University of California (San Francisco)Residency, Neurological Surgery, 2014 - 2021
- University of Rochester School of Medicine and DentistryClass of 2014
Certifications & Licensure
- CA State Medical License 2015 - 2025
- AZ State Medical License 2022 - 2023
Publications & Presentations
PubMed
- 206 citationsLow-density lipoprotein receptor-related protein-1: a serial clearance homeostatic mechanism controlling Alzheimer's amyloid β-peptide elimination from the brain.Berislav V. Zlokovic, Rashid Deane, Abhay P. Sagare, Robert D. Bell, Ethan A. Winkler
Journal of Neurochemistry. 2010-12-01 - 448 citationsGLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degenerationEthan A. Winkler, Yoichiro Nishida, Abhay P. Sagare, Sanket V Rege, Robert D. Bell
Nature Neuroscience. 2015-04-01 - 143 citationsA single-cell atlas of the normal and malformed human brain vasculature.Ethan A Winkler, Chang N Kim, Jayden M Ross, Joseph H Garcia, Eugene Gil
Science. 2022-03-04
Press Mentions
- Arteriovenous Malformations (AVMs) | Surgical Treatment Options at UCSFAugust 22nd, 2024
- Mapping Cells to Understand Vascular DiseaseFebruary 25th, 2022
- Atlas of Brain Vasculature Identifies New Cell Types and Links Immune Cells with Hemorrhagic StrokeJanuary 28th, 2022
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