EricaBEsrickMD

Pediatric Hematology & Oncology • Boston, MA

Physician

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Office
300 Longwood Ave
Boston, MA 02115
Phone+1 617-355-6000

Education & Training

Boston Children’s Hospital/Boston Medical CenterFellowship, Pediatric Hematology/Oncology, 2007 - 2010
Boston Children’s Hospital/Boston Medical CenterResidency, Pediatrics, 2005 - 2007
Harvard Medical SchoolClass of 2003

Certifications & Licensure

MA State Medical License 2010 - 2025
IL State Medical License 2004 - 2014
American Board of Pediatrics Pediatric Hematology-Oncology

Clinical Trials

Pilot and Feasibility Trial of Plerixafor for Hematopoietic Stem Cell (HSC) Mobilization in Patients With Sickle Cell Disease Pilot and Feasibility Trial of Plerixafor for Hematopoietic Stem Cell (HSC) Mobilization in Patients With Sickle Cell Disease Start of enrollment: 2017 Jan 01
Completed
Phase 1
Gene Transfer for Sickle Cell Disease Start of enrollment: 2018 Feb 13
Active, not recruiting
Phase 1

Publications & Presentations

PubMed

191 citations
Post-Transcriptional Genetic Silencing of BCL11A to Treat Sickle Cell Disease
Erica B. Esrick, Leslie Lehmann, Alessandra Biffi, Maureen Achebe, Christian Brendel
The New England Journal of Medicine. 2021-01-21
288 citations
Highly efficient therapeutic gene editing of human hematopoietic stem cells.
Yuxuan Wu, Jing Zeng, Benjamin P. Roscoe, Pengpeng Liu, Qiuming Yao
Nature Medicine. 2019-03-25
236 citations
Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing.
Jian Xu, Cong Peng, Vijay G. Sankaran, Zhen Shao, Erica B. Esrick
Science. 2011-11-18

Abstracts/Posters

Preliminary Results of a Phase 1/2 Clinical Study of Zinc Finger Nuclease-Mediated Editing of BCL11A in Autologous Hematopoietic Stem Cells for Transfusion-Dependent B...
Erica B. Esrick, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019

Press Mentions

ASGCT News: Hematologist David Williams Wins 2023 ASGCT Founder’s AwardMay 17th, 2023
What Caused the Blood Malignancies Linked to Gene Therapy for Sickle Cell Disease?February 15th, 2022
7 Incredible Health Breakthroughs Worth Celebrating in 2020November 28th, 2020
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