Eric Stephen White MD MS

PubMed

• Effects of nintedanib on circulating biomarkers of idiopathic pulmonary fibrosis.
  R Gisli Jenkins, Vincent Cottin, Yasuhiko Nishioka, Imre Noth, Eric S White
  ERJ Open Research. 2024-11-01
• Assessing How Patients Feel, Function, and Survive in Idiopathic Pulmonary Fibrosis: The Best Is the Enemy of the Good.
  Susanne Stowasser, Gregory P Cosgrove, Eric S White
  American Journal of Respiratory and Critical Care Medicine. 2024-08-01
• 2 citations
  Circulating biomarkers and progression of idiopathic pulmonary fibrosis: data from the INMARK trial.
  Toby M Maher, R Gisli Jenkins, Vincent Cottin, Yasuhiko Nishioka, Imre Noth
  ERJ Open Research. 2024-07-01

Journal Articles

• Repair and Regeneration of the Respiratory System: Complexity, Plasticity, and Mechanisms of Lung Stem Cell Function  
  BL Hogan, CE Barkauskas, HA Chapman, JA Epstein, R Jain, CC Hsia, L Niklason, E Calle, A Le, SH Randell, J Rock, M Snitow, M Krummel, BR Stripp, T Vu, ES White, JA Whi..., Cell Stem Cell, 8/1/2014
• Association Between Lung Microbiome and Disease Progression in IPF: A Prospective Cohort Study  
  MK Han, Y Zhou, S Murray, N Tayob, I Noth, VN Lama, BB Moore, ES White, KR Flaherty, GB Huffnagle, FJ Martinez for the COMET Investigators, Lancet Resp Med, 7/1/2014
• miR-92a regulates TGF-Beta1-induced WISP1 expression in pulmonary fibrosis  
  Berschneider B, Ellwanger DC, Baarsma HA, Thiel C, Shimbori C, White ES, Kolb M, Neth P, Konigshoff M, Int J Biochem & Cell Biol, 6/19/2014
• Prostaglandin E2 Inhibits Aplah-Smooth Muscle Actin Transcription During Myofibroblast Differentiation via Distinct Mechanisms of Modulation of Serum Response Factor a...  
  Penke LR, Huang SK, White ES, Peters-Golden M, J Biol Chem, 6/13/2014
• Matrix Biology of Idiopathic Pulmonary Fibrosis: A Summary from a National Heart, Lung and Blood Institute Workshop  
  VJ Thannickal, CA Henke, JC Horowitz, PW Noble, J Roman, PJ Sime, Y Zhou, RG Wells, ES White, DJ Tschumperlin, Am J Physiology: Lung Cell Mol Phys, 6/1/2014
• A Randomized Double-Blind, Placebo-Controlled Trial of Soluble Tumor Necrosis Factor Receptor: Enbrel (Etanercept) for the Treatment of Idiopathic Pneumonia Syndrome F...  
  GA Yanik, MM Horowitz, DJ Weisdorf, BR Logan, VT Ho, RJ Soiffer, SL Carter, J Wu, JR Wingard, NL Difronzo, JL Ferrara, S Giralt, DK Madtes, R Drexler, ES White, KR Cooke, Biol. Blood Marrow Transplant, 6/1/2014
• Arsenic trioxide inhibits transforming growth factor-Beta1-induced fibroblast to myofibroblast differentiation in vitro and bleomycin induced lung fibrosis in vivo  
  F Luo, Y Zhuang, MD Sides, CG Sanchez, B Shan, ES White, JA Lasky, Resp Res, 4/24/2014
• Fibrotic extracellular matrix activates a profibrotic positive feedback loop  
  MW Parker, D Rossi, M Peterson, K Smith, K Sikstrom, ES White, JE Connett, CA Henke, O Larsson, PB Bitterman, J Clin Invest, 4/1/2014
• Future Directions in Idiopathic Pulmonary Fibrosis Research: An NHLBI Workshop Report  
  TS Blackwell, AM Tager, Z Borok, BB Moore, DA Schwartz, KJ Anstrom, Z Bar-Joseph, P Bitterman, MR Blackburn, W Bradford, KK Brown, HA Chapman, HR Collard, GP Cosgrove,..., Am J Respir Crit Care Med, 1/15/2014
• Fibronectin EDA Promotes Chronic Cutaneous Fibrosis Through Toll-Like Receptor Signaling  
  Bhattacharyya S, Tamaki Z, Wang W, Hinchcliff M, Hoover P, Getsios S, White ES, Varga J, Sci Transl Med, 1/1/2014
• Chitinase 3-like 1 Suppresses Injury and Fibroproliferative Responses in Pulmonary Fibrosis  
  Y Zhou, H Peng, HX Sun, XY Peng, C Tang, Y Gan, XC Chen, AM Mathur, B Hu, M Slade, RR Montgomery, AC Shaw, RJ Homer, ES White, CM Lee, MW Moore, M Gulati, CG Lee, JA E..., Sci Transl Med, 1/1/2014
• Maternal infection with Schistosoma japonicum induces a pro-fibrotic response in neonates  
  EA McDonald, L Cheng, B Jarilla, MJ Sagliba, A Gonzal, AJ Amoylen, R Olveda, L Acosta, D Baylink, ES White, JF Friedman, JD Kurtis, Infect Immun, 1/1/2014
• Upregulation of Heparan Sulfate 6-O-Sulfation in Idiopathic Pulmonary Fibrosis  
  J Lu, L Auduong, ES White, X Yue, Am J Resp Cell Mol Biol, 1/1/2014
• Human iPS cell-derived alveolar epithelium repopulates lung extracellular matrix  
  M Ghaedi, EA Calle, JJ Mendez, AL Gard, J Balestrini, A Booth, PF Bove, L Gui, ES White, LE Niklason, J Clin Invest, 11/1/2013
• X-Linked Inhibitor of Apoptosis regulates lung fibroblast resistance to Fas-mediated apoptosis  
  IO Ajayi, TH Sisson, PDR Higgins, AJ Booth, RL Sagana, SK Huang, ES White, JE King, BB Moore, JC Horowitz, Am J Resp Cell Mol Biol, 7/1/2013
• Schistosoma japonicum soluble egg antigens attenuate invasion in a first trimester human placental trophoblast model  
  EA McDonald, JF Friedman, S Sharma, L Acosta, S Pond-Tor, L Cheng, ES White, JD Kurtis, PLoS Negl Trop Dis, 6/6/2013
• Histone modifications are responsible for decreased Fas expression and apoptosis resistance in fibrotic lung fibroblasts  
  SK Huang, AM Scruggs, J Donaghy, JC Horowitz, Z Zaslona, S Przybranowski, ES White and M Peters-Golden, Cell Death and Disease, 5/2/2013
• The Myofibroblast Matrix: Implications for Tissue Repair and Fibrosis  
  F Klingberg, B Hinz, and ES White, J Pathol, 1/1/2013
• Periostin promotes fibrosis and predicts progression in patients with Idiopathic Pulmonary Fibrosis  
  PK Naik, PD Bozyk, JK Bentley, AP Popova, CM Birch, CA Wilke, CD Fry, ES White, TH Sisson, N Tayob, B Carnemolla, KR Flaherty, MB Hershenson, S Murray, FJ Martinez, BB..., Am J Physiol-Lung Cell Mol Phys, 12/1/2012
• Acellular Normal and Fibrotic Human Lung Matrices as a Culture System for In Vitro Investigation  
  AJ Booth, R Hadley, AM Cornett, AA Dreffs, SA Matthes, JL Tsui, K Weiss, JC Horowitz, VF Fiore, TH Barker, BB Moore, FJ Martinez, LE Niklason, ES White, Am J Resp Crit Care Med, 11/1/2012
• Soluble Tumor Necrosis Factor Receptor: Enbrel (etanercept) for Sub-Acute Pulmonary Dysfunction Following Allogeneic Stem Cell Transplantation  
  GA Yanik, S Mineishi, JE Levine, CL Kitko, ES White, MT Vander Lugt, AC Harris, T Braun, and KR Cooke, Biol Blood Marrow Transpl, 7/1/2012
• IL-17 Drives Pulmonary Eosinophilia Following Repeated Aspergillus fumigatus Conidia Exposure  
  BJ Murdock, AB Shreiner, AS Akha, NR Falkowski, RA McDonald, ES White, GB Toews, and GB Huffnagle, Infect Immun, 4/1/2012
• Recipient-Derived EDA Fibronectin Promotes Cardiac Allograft Fibrosis  
  AJ Booth, SC Wood, G Lu, AF Muro, ES White, and DK Bishop, J Pathol, 3/1/2012
• PTEN Directly Activates the Actin Depolymerization Factor Cofilin-1 During PGE2-Mediated Inhibition of Phagocytosis of Fungi  
  CH Serezani, S Kane, AI Medeiros, AM Cornett, SH Kim, MM Marques, SP Lee, C Lewis, E Bourdonnay, MN Ballinger, ES White, M Peters-Golden, Sci Signal, 2/7/2012
• Fibrotic and sclerotic manifestations of chronic graft-versus-host disease  
  CL Kitko, ES White, K Baird, Biol Blood Marrow Transplant, 1/1/2012
• Join now to see all

Books/Book Chapters

• Interstitial Pulmonary and Bronchiolar Disorders. Lung Biology in Health and Disease Series, Vol. 227 
  Chapter: Pulmonary Sarcoidosis. 
  JP Lynch III, MC Fishbein, and ES WhiteEditors: J.P. Lynch.Informa Healthcare USA, New York, NY2008
• Sarcoidosis. Lung Biology in Health and Disease Series, Vol. 210 
  Chapter: Corticosteroid therapy for sarcoidosis. 
  Page 689 - 716ES White, DA Zisman, DT Keena, and JP Lynch, IIIEditors: R.P. Baughman, Claude Lenfant.Marcel Dekker, New York, NY2006
• Eur Resp Mon 
  Chapter: Pulmonary Sarcoidosis. 
  Page 105 - 129JP Lynch III and ES White2005
• Idiopathic Pulmonary Fibrosis. Lung Biology in Health and Disease Series, Vol. 185 
  Chapter: The role of polymorphonuclear leukocytes in the pathogenesis of idiopathic pulmonary fibrosis. 
  Page 341 - 357ES White and TJ StandifordEditors: J. P. Lynch III, Claude Lenfant.Marcel Dekker, New York, NY2004
• Join now to see all

Abstracts/Posters

• "Models of ECM in Lung Research."
  Eric Stephen White, MD, Extracellular Matrix in Lung Disease Workshop, NHLBI, Bethesda, MD, 9/17/2014
• "Pulmonary fibrosis: receptors, signalling pathways and mesenchymal cells."
  Eric Stephen White, MD, European Respiratory Society International Congress, Munich, Germany, 9/6/2014
• "Fibroblasts and the Abnormal Matrix as the Central Player in IPF Pathogenesis."
  Eric Stephen White, MD, Scientific Symposium "ATS Mythbusters: Repetitive Micro-Injuries Drive IPF Progression", American Thoracic Society International Conference, San Diego, CA, 5/20/2014
• "Can't Sarcoidosis Look like ANYTHING?"
  Eric Stephen White, MD, University of Michigan Department of Medicine 2nd Annual Update in Internal Medicine, Ann Arbor, MI, 5/9/2014
• Relationships between Quantitative FDG PET Parameters, Treatment and Disease Activity in Cardiac Sarcoidosis.
  VL Murthy, EP Ficaro, J Meden, ES White, JR Corbett, Society of Nuclear Medicine & Molecular Imaging Annual Meeting, St. Louis, MO, 1/1/2014
• Acellular Normal Lung Matrices As A Long-term Human Amniotic Fluid Stem Cell Culture System.
  O Garcia, A Petrosyan, G Turcatel, D Warburton, ES White, B Driscoll, L Perin, American Thoracic Society International Conference, San Diego, CA, 1/1/2014
• Critical Roles Of Krupple-Like Factor 4 And Forkhead Box O3A In Regulating Lung Fibroblast Proliferation.
  LRK Penke, SK Huang, SH Wettlaufer, ES White, M Peters-Golden, American Thoracic Society International Conference, San Diego, CA, 1/1/2014
• Growth-Factor Driven Down-Regulation Of Secreted Frizzled-Related Protein 1 (Sfrp1) Augments Fibroblast Invasion.
  B Oehrle, G Burgstaller, M Irmler, S Dehmel, A Cornett, T Hwang, J Beckers, S Krauss-Etschmann, ES White, S Meiners, O Eickelberg, American Thoracic Society International Conference, San Diego, CA, 1/1/2014
• No Evidence For Epigenetic Regulation Of PTEN In IPF Lung Fibroblasts.
  E Speelmon, SK Huang, R Sagana, ES White, American Thoracic Society International Conference, San Diego, CA, 1/1/2014
• "The NIH Lung Repair and Regeneration Consortium (LRRC): An Update." Chair, Scientific Symposium
  Eric Stephen White, MD, American Thoracic Society International Conference, Philadelphia, PA, 5/21/2013
• "The Role Of Lung ECM In Driving Cellular Phenotype During Lung Repair and Regeneration."
  Eric Stephen White, MD, Scientific Symposium "The NIH Lung Repair and Regeneration Consortium (LRRC): An Update.", American Thoracic Society International Conference, Philadelphia, PA, 5/21/2013
• "Proteomic analysis of the lung ECM: applications to help understand disease."
  Eric Stephen White, MD, Scientific Symposium "Exciting Technological Advances for Understanding the Extracellular Matrix", American Thoracic Society International Conference, Philadelphia, PA, 5/20/2013
• "Understanding The Role of The ECM In Lung Regeneration And Repair."
  Eric Stephen White, MD, Scientific Symposium "Exciting Technological Advances for Understanding the Extracellular Matrix", American Thoracic Society International Conference, Philadelphia, PA, 5/20/2013
• The Use of Early Spirometric Changes and IGF-1 Levels for the Detection of Patients At Risk for BOS.
  S Abedin, G Yanik, J Magenau, A Pawarode, S Goldstein, C Kitko, ES White, DR Couriel, American Society for Blood and Marrow Transplantation Tandem Meetings, Salt Lake City, UT, 1/1/2013
• Biomarkers of Extracellular Matrix Remodeling in Chronic GVHD.
  C Kitko, R Saliba, SW Choi, P Reddy, SC Goldstein, J Magenau, A Pawarode, M Kennel, JE Levine, ES White, DR Couriel, American Society for Blood and Marrow Transplantation Tandem Meetings, Salt Lake City, UT, 1/1/2013
• Biomarkers of Extracellular Matrix Remodeling in Chronic GVHD.
  C Kitko, R Saliba, SW Choi, P Reddy, SC Goldstein, J Magenau, A Pawarode, M Kennel, JE Levine, ES White, DR Couriel, European Group For Blood and Marrow Transplantation, London, UK, 1/1/2013
• Randomized, Double Blind, Placebo-Controlled Trial of a TNF inhibitor (etanercept) for the Treatment of Idiopathic Pneumonia Syndrome (IPS) after Allogeneic Stem Cell ...
  GA Yanik, VT Ho, M Horowitz, DJ Weisdorf, BR Logan, J Wu, RJ Soiffer, JR Wingard, JE Levine, JLM Ferrara, SA Giralt, ES White, SL Carter, N DiFronzo, KR Cooke, American Society for Blood and Marrow Transplantation Tandem Meetings, Salt Lake City, UT, 1/1/2013
• Competitive TNF Inhibitor (etanercept) for the Treatment of Idiopathic Pneumonia Syndrome (IPS) Following Allogeneic Stem Cell Transplantation (SCT). A Joint Pediatric...
  GA Yanik, S Grupp, MA Pulsipher, JE Levine, KR Schultz, ES White, DA Wall, B Langholz, CC Dvorak, K Alangaden, KR Cooke, American Society for Blood and Marrow Transplantation Tandem Meetings, Salt Lake City, UT, 1/1/2013
• Overexpression Of Heparan Sulfate 6-O-Sulfotransferases In Idiopathic Pulmonary Fibrosis.
  J Lu, L Auduong, ES White, X Yue, American Thoracic Society International Conference, Philadelphia, PA, 1/1/2013
• Utility Of Transbronchial Biopsy Versus Surgical Lung Biopsy In The Diagnosis Of Patients With Suspected Idiopathic Interstitial Pneumonia.
  J Votava, J Belperio, EA Kazerooni, A Lagstein, JL Myers, RH Simon, TH Sisson, B Sundaram, ES White, D Zisman, KR Flaherty, American Thoracic Society International Conference, Philadelphia, PA, 1/1/2013
• Clinical Outcomes In Patients With Idiopathic Pulmonary Fibrosis: Data From COMET.
  JP Scott, N Tayob, MK Han, FJ Martinez, S Murray, ES White, KR Flaherty, American Thoracic Society International Conference, Philadelphia, PA, 1/1/2013
• Characterization Of Lung Epithelial Phenotypes In Cells Cultured Within Normal And Fibrotic Human Acellular Lung Matrices.
  R Hadley, A Booth, A Cornett, ES White, American Thoracic Society International Conference, Philadelphia, PA, 1/1/2013
• The Role Of Plakoglobin In Idiopathic Pulmonary Fibrosis.
  S Matthes, T LaRouere, BB Moore, JC Horowitz, ES White, American Thoracic Society International Conference, Philadelphia, PA, 1/1/2013
• TLR4 As A Receptor For EDA-Containing Fibronectin.
  A Booth, Z Breslin, B Mitchell, ES White, American Thoracic Society International Conference, Philadelphia, PA, 1/1/2013
• Serum Osteopontin, Type I Collagen Telopeptide, And Pro-Collagen I Carboxy-Terminal Peptide Are Potential Predictors Of Longitudinal DLCO Changes In Idiopathic Pulmona...
  Y Bauer, ES White, J Kurtis, FJ Martinez, B Renault, A Trebaul, P Groenen, S Roux, I Leconte, A Morganti, O Nayler, American Thoracic Society International Conference, Philadelphia, PA, 1/1/2013
• Join now to see all

Lectures

• "The Future of IPF Basic Science Research." 
  Mont Tremblant, Canada - 9/24/2014
• Fibronectin isoforms in lung fibrosis." Invited Speaker 
  Munich International Autumn School, Munich, Germany - 9/4/2014
• "The Extracellular Matrix in Pulmonary Fibrosis: More Than Just an Endpoint." Visiting Professor 
  Weill Cornell Medical College, New York, NY - 8/28/2014
• "Extracellular Matrix-Pathogenic and Prognostic in IPF." Visiting Professor 
  National Jewish Health, Denver, CO - 7/24/2014
• "Extracellular Matrix Stiffness and Fibroblast Function." 
  Aspen, CO - 6/5/2014
• "ATS Program of Research." 
  San Diego, CA - 5/18/2014
• "The Aging Lung Matrix." 
  San Diego, CA - 5/17/2014
• "Anatomy and cellular differences-reagents and models needed." Workgroup Chair 
  Louisville, KY - 4/27/2014
• Grand Rounds: "Registries, Biorepositories, and Biomarkers: The Future of Interstitial Lung Disease Research." 
  Danbury, CT - 4/17/2014
• "Extracellular Matrix in Pulmonary Fibrosis: Not just an Endpoint." Visiting Professor 
  Louisiana State University Health Science Center Department of Physiology, New Orleans, LA - 3/20/2014
• "Grantsmanship" Panelist 
  1/1/2014
• "Fibrosis-Therapeutic Target or Inevitable Outcome?" Invited Speaker 
  New York Academy of Sciences, New York, NY - 10/22/2013
• "Standardization of animal models of IPF across centers-scientific necessity or ethical mandate?" Invited Speaker 
  Paris, France - 10/4/2013
• "The Scientific Process as it Relates to Human Lung Disease Research." 
  Philadelphia, PA - 8/24/2013
• Grand Rounds: "Idiopathic Pulmonary Fibrosis: Where are we going?" 
  Danbury, CT - 8/19/2013
• "The Extracellular Matrix in Pulmonary Fibrosis: More Than Just an Endpoint." Invited Speaker 
  Giessen, Germany - 6/27/2013
• "Extracellular Matrix in Interstitial Lung Disease: Pathogenic and prognostic?" Visiting Professor 
  University of Pittsburgh Division of Pulmonary, Allergy, and Critical Care Medicine, Pittsburgh, PA - 6/4/2013
• "Modeling Human Lung Disease: A Toolbox for Meaningful Measurements." Chair, Post-Graduate Course 
  Philadelphia, PA - 5/17/2013
• "Human Lung Extracellular Matrix: Defining the Substrate." 
  Hilton Head, SC - 3/20/2013
• "Extrapulmonary Sarcoidosis-Diagnosis and Management." 
  The University of Michigan - 3/1/2013
• Research in Progress: "Extracellular matrix biomarkers in IPF and other fibrotic disorders" 
  Division of Pulmonary and Critical Care Medicine, The University of Michigan - 2/1/2013
• "Sarcoidosis Basics." 
  The University of Michigan - 1/1/2013
• "Lung ECM in Development, Homeostasis, and Disease." 
  1/1/2013
• "Role of Extracellular Matrix in Lung Fibrosis and Regeneration" 
  The University of Michigan - 10/1/2012
• "Acellular Human Lung to Examine the Role of Extracellular Matrix in Lung Fibrosis." 
  Ann Arbor, MI - 9/13/2012
• Join now to see all

Other

• Sarcoidosis: diagnosis and management 
  ES White, Audio-Digest Internal Medicine, Volume 61, Issue 34, ISSN 0271-1303
  9/14/2014
• Brain and Nerves. 
  PD Bozyk and ES White, Sarcoidosis: A Primer, American College of Chest Physicians Patient Education Guide (Editors: LS Eff
  1/1/2013
• Lungs. 
  PD Bozyk and ES White, Sarcoidosis: A Primer, American College of Chest Physicians Patient Education Guide (Editors: LS Eff
  1/1/2013