Eric Albert Mellon MD PhD

PubMed

• Stereotactic radiosurgery for multiple small brain metastases using gamma knife versus single-isocenter VMAT: Normal brain dose based on lesion number and size.
  Abram Abdou, Timoteo Almeida, Elizabeth Bossart, Irene Monterroso, Eric A Mellon
  Journal of Applied Clinical Medical Physics. 2025-03-19
• Magnetic Resonance Imaging Relaxometry for Glioblastoma Response Assessment During Radiation Therapy on a 0.35 T Magnetic Resonance Imaging Linear Accelerator.
  Natalia Lutsik, Siamak P Nejad-Davarani, Alessandro Valderrama, Janette Herr, Kaylie Cullison
  International Journal of Radiation Oncology, Biology, Physics. 2025-02-22
• T1 Gadolinium-Enhanced Magnetic Resonance Imaging of Glioblastoma: What You See Is Not What You Get.
  Jonathan B Bell, Eric A Mellon
  International Journal of Radiation Oncology, Biology, Physics. 2025-02-01

Journal Articles

• Dosimetric analysis of stereotactic body radiotherapy for pancreatic cancer using MR-guided Tri-60Co unit, MR-guided linac, and conventional linac based plans  
  Ramey SJ, Padgett KR, Lamichhane N, Neboori HJ, Kwon D, Mellon EA, Brown K, Duffy M, Victoria J, Dogan N, Portelance L, Pract Radiat Oncol, 1/1/2018
• Automated inverse optimization facilitates lower doses to normal tissue in pancreatic stereotactic body radiotherapy Automated inverse optimization facilitates lower d...  
  Mihaylov IB, Mellon EA, Yechieli R, Portelance L, PLoS One, 1/1/2018
• Impact of sarcopenia in borderline resectable and locally advanced pancreatic cancer patients receiving stereotactic body radiation therapy  
  Jin WH, Mellon EA, Frakes JM, Murimwa GZ, Hodul PJ, Pimiento JM, Malafa MP, Hoffe SE, J Gastrointest Oncol, 1/1/2018
• Assessment of the radiotherapy model in the Dominican Republic and its impact on the Caribbean islands  
  Gajjar SR, Mellon EA, Castaneda SA, Zoghbi SR, Llorente R, DeGennaro V, Grover S, Ventura NC, Int J Radiat Oncol Biol Phys, 1/1/2018
• Daily tracking of glioblastoma resection cavity, cerebral edema, and tumor volume with MRI-guided radiation therapy  
  Mehta S, Gajjar SR, Padgett KR, Asher D, Stoyanova R, Ford JC, Mellon EA, Cureus, 1/1/2018
• Stereotactic ablative radiotherapy in the treatment of liver tumors  
  Spieler BO, Portelance L, Mellon EA, Appl Radiat Oncol, 1/1/2018
• Analysis of magnetic resonance image signal fluctuations acquired during MR-guided radiotherapy  
  Breto AL, Padgett KR, Ford JC, Kwon D, Chang C, Fuss M, Stoyanova R, Mellon EA, Cureus, 1/1/2018
• Optimization of the Prescription Isodose Line for Gamma Knife Radiosurgery Using the Shot Within Shot Technique  
  Eric Mellon, Maria I Monterroso, BioMed Central
• Frequency of whole breast radiation therapy following intraoperative radiation therapy due to criteria identified by lumpectomy  
  Mellon EA, Orman A, Montejo ME, Laronga C, Joya LE, Lee MC, Hoover SJ, Khakpour N, Kubal PF, Diaz R, Brachytherapy, 1/1/2017
• CB-CHOP: A simple acronym for evaluating a radiation treatment plan  
  Dean M, Jimenez R, Mellon E, Fields E, Yechieli R, Mak R, Appl Radiat Oncol, 1/1/2017
• Predictors and survival for pathologic tumor response grade in borderline resectable and locally advanced pancreatic cancer treated with induction chemotherapy and neo...  
  Mellon EA, Jin W, Hodul PJ, Frakes JM, Strom TJ, Chuong MD, Centeno BA, Springett GM, Shridhar R, Malafa MP, Hoffe SE, Acta Oncologica, 1/1/2017
• A genome-based model for adjusting radiotherapy dose (GARD): a retrospective, cohort-based study  
  Scott JG, Berglund A, Mihaylov I, Fulp WJ, Yue B, Welch E, Caudell JJ, Ahmed K, Strom TS, Mellon EA, Venkat P, Johnstone P, Foekens J, Lee J, Schell M, Brenner D, Dalt..., Lancet Oncol, 1/1/2017
• Transarterial yttrium-90 radioembolization treatment of patients with liver dominant metastatic renal cell cancer  
  Kis B, Shah J, Choi J, El-Hadded G, Sweeney J, Biebel B, Mellon EA, Frakes JM, Hoffe SE, Fishman MN, Shridhar R, J Vasc Interv Radiol, 1/1/2017
• FOLFIRINOX for locally advanced pancreatic cancer: a systematic review and patient-level meta-analysis  
  Suker M, Beumer BR, Sadot E, Marthey L, Faris JE, Mellon EA, El-Rayes BF, Wang-Gillam A, Lacy J, Hosein PJ, Moorcraft SY, Conroy T, Hohla F, Allen PJ, Taieb J, Hong TS..., Lancet Oncol, 1/1/2016
• Outcomes in patients with brain metastasis from esophageal carcinoma  
  Kothari N, Mellon EA, Hoffe SE, Frakes J, Shridhar R, Pimiento J, Meredith K, Tran N, Saeed N, Almhanna K, J Gastrointest Oncol, 1/1/2016
• Favorable perioperative outcomes after resection of borderline resectable pancreatic cancer treated with neoadjuvant stereotactic radiation and chemotherapy compared w...  
  Mellon EA, Strom TJ, Hoffe SE, Frakes JM, Springett GM, Hodul PJ, Malafa MP, Chuong MD, Shridhar R, J Gastrointest Oncol, 1/1/2016
• Health-Related Quality of Life Changes due to High-Dose-Rate Brachytherapy, Low-Dose-Rate Brachytherapy, or Intensity Modulated Radiation Therapy for Prostate Cancer  
  Strom TJ, Cruz AA, Figura NB, Shrinath K, Nethers K, Mellon EA, Fernandez DC, Saini AS, Hunt DC, Heysek RV, Wilder RB, Brachytherapy, 1/1/2015
• Quality of life after high-dose-rate brachytherapy monotherapy for prostate cancer  
  Contreras J, Wilder RB, Mellon EA, Strom TJ, Fernandez DF, Biagioli MC, Int Braz J Urol, 1/1/2015
• Dosimetric coverage of the prostate, normal tissue sparing, and acute toxicity with high-dose-rate brachytherapy for large prostate volumes  
  Yang G, Strom TJ, Wilder RB, Shrinath K, Mellon EA, Fernandez DC, Biagioli MC, Int Braz J Urol, 1/1/2015
• A dosimetric study of polyethylene glycol hydrogel in 200 prostate cancer patients treated with high-dose rate brachytherapy � intensity modulated radiation therapy  
  Strom TJ, Wilder RB, Fernandez DC, Mellon EA, Saini AS, Pow-Sang JM, Spiess PE, Sexton WJ, Poch MA, Biagioli MC, Radiother Oncol, 1/1/2015
• High-dose-rate brachytherapy with or without intensity modulated radiation therapy as salvage treatment for an isolated, gross local recurrence of prostate cancer post...  
  Strom TJ, Wilder RB, Fernandez DC, Mellon EA, Saini AS, Hunt DC, Biagioli MC, Brachytherapy, 1/1/2013
• Stereotactic body radiation therapy for locally advanced and borderline resectable pancreatic cancer is effective and well tolerated  
  Chuong MD, Springett GM, Freilich JM, Park CK, Weber JM, Mellon EA, Hodul PJ, Malafa MP, Meredith KL, Hoffe SE, Shridhar R, Int J Radiat Oncol Biol Phys, 1/1/2013
• Measurement of creatine kinase reaction rate in human brain using magnetization transfer image-selected in vivo spectroscopy (MT-ISIS) and a volume 31P/1H radiofrequen...  
  Jeong EK, Sung YH, Kim SE, Zuo C, Shi X, Mellon EA, Renshaw PF, NMR Biomed, 1/1/2011
• NMR metabolic and physiological markers of therapeutic response  
  Lee SC, Poptani H, Delikatny EJ, Pickup S, Nelson DS, Schuster SJ, Nasta SD, Svoboda J, Goldstein SC, Wallace SG, Loevner LA, Mellon EA, Reddy R, Glickson JD, Adv Exp Med Biol, 1/1/2011
• Mapping of cerebral oxidative metabolism with MRI  
  Mellon EA, Beesam RS, Reddy SG, Reddy A, Reddy R, Proc Natl Acad Sci, 1/1/2010
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Books/Book Chapters

• Radiation Therapy for Liver Cancer 
  Chapter: Radiation Therapy for Liver Tumors: Future Directions. 
  Mellon EA, Murimwa G, Hoffe SEEditors: Meyer, J and Schefter, T.Springer Publishing2017
• Honors Medical Students: Becoming America�s Best and Brightest 
  Chapter: Becoming a Radiation Oncology Resident. 
  Mellon EA, Orellana C, Orellana A. Dr. Eric MellonEditors: Orellana, C and Orellana, A.MedicalSchoolReport.com Publishing2012

Abstracts/Posters

• A Feasibility Study of Radiation Therapy Dose Escalation Guided by Spectroscopic Magnetic Resonance Imaging in Patients with Glioblastoma.
  Mellon EA, Gurbani S, Sheriff S, Goryawala M, Schriebmann E, Kleinberg L, Shu HK, Maudsley A, Shim H, Society for NeuroOncology, New Orleans, LA, 1/16/2018
• Evaluation of Hyperarc SRS planning for linacs with standard and micro MLC: comparison with Gamma Knife.
  Bossart E, Monterroso M, Elsayyad N, Mellon E, Dogan N, Med Phys, 1/1/2018
• Adaptive versus non-adaptive MRI-guided radiation treatments for pancreatic cancer: A dosimetric study.
  Spieler BO, El Bared N, Padgett K, Brown KM, Portelance L, Mellon EA, J Clin Oncol; GI Symposium -- American Society of Clinical Oncology, San Francisco, CA, 1/1/2018
• A feasibility study of radiation therapy dose escalation guided by spectroscopic MRI in patients with glioblastoma.
  Gurbani S, Mellon E, Weinberg B, Schreibmann E, Maudsley AA, Sheriff S, Barker PB, Kleinberg L, Cooper LAD, Shu HG, Shim H, International Society of Magnetic Resonance in Medicine, Paris, France, 1/1/2018
• Dosimetric Analysis of Stereotactic Body Radiation Therapy for Pancreatic Cancer using MR-Guided Tri-60Co Unit, MR-Guided LINAC, and Conventional LINAC Based Plans.
  Ramey SJ, Padgett KR, Lamichhane N, Neboori H, Kwon D, Mellon EA, Brown K, Duffy M, Victoria JR, Dogan N, Portelance L, Int J Radiat Oncol Biol Phys; American Society for Radiation Oncology, San Antonio, TX, 1/1/2018
• Effect of Radiation Therapy Duration on Overall Survival in Anal Squamous Cell Carcinoma: A National Analysis.
  Mehta S, Ramey SJ, Kwon D, Rich BJ, Wolfson AH, Yechieli R, Portelance L, Mellon EA, Int J Radiat Oncol Biol Phys; American Society for Radiation Oncology, San Antonio, TX, 1/1/2018
• Assessment of Radiotherapy Resources in the Dominican Republic.
  Gajjar S, Balogun O, Castaneda SA, DeGennaro V, Grover S, Llorente R, Mehta S, Mellon EA, Zoghbi SER, Ventura NC, Int J Radiat Oncol Biol Phys; American Radium Society, Orlando, FL, 1/1/2018
• Combined use of radiosurgery with concurrent PD-1/PD-L1 inhibition for metastatic brain lesions of NSCLC.
  Azzam G, Park W, Mellon E, Markoe A, Elsayyad N, Lopes G, Portelance L, Int J Radiat Oncol Biol Phys; American Radium Society, Orlando, FL, 1/1/2018
• Interfraction variation in stomach volume increase dose to stomach and duodenum in pancreas stereotactic body radiotherapy and is mitigated by daily adaptive magnetic ...
  Spieler BO, El Bared N, Padgett K, Brown KM, Portelance L, Mellon EA, Int J Radiat Oncol Biol Phys, 1/1/2018
• Rates of whole breast radiation therapy following intraoperative radiation therapy using 2009 and 2016 ASTRO consensus guidelines.
  Mellon EA, Diaz R, Montejo ME, Laronga C, Lee MC, Hoover SJ, Khakpour N, Kubal PF, Orman AGB, American Society for Radiation Oncology, San Diego, CA, 1/25/2017
• Spectroscopic MRI predicts recurrence patterns in glioblastoma.
  Gurbani S, Kleinberg L, Zhong J, Olson J, Mellon E, Maudsley A, Shu H, Shim H, Neuro-Oncology; Society for NeuroOncology, San Francisco, CA, 1/1/2017
• Rates of Whole Breast Radiation Therapy Following Intraoperative Radiation Therapy Using 2009 and 2016 ASTRO Consensus Guidelines.
  Mellon EA, Diaz R, Montejo ME, Laronga C, Lee MC, Hoover SJ, Khakpour N, Kubal PF, Orman AGB, Int J Radiat Oncol Biol Phys, 1/1/2017
• Experience with MRI-guided stereotactic ablative radiotherapy (SABR) for the treatment of spinal metastases.
  Llorente R, Yechieli R, Samuels M, Takita C, Ford JC, Brown K, Mellon EA, Int J Radiat Oncol Biol Phys; American Society for Radiation Oncology, San Diego, CA, 1/1/2017
• Outcomes of adjuvant radiotherapy and lymph node harvest in elderly patients with pancreatic cancer.
  Frakes JM, Shridhar R, Mellon E, Hoffe SE, Almhanna K, Malafa MP, Springett G, Meredith KL, J Am Coll Surg; American College of Surgeons Clinical Congress, San Diego, CA, 1/1/2017
• Can total psoas area predict toxicity after stereotactic body radiation therapy in borderline resectable and locally advanced pancreatic cancers?
  Jin W, Mellon EA, Frakes JM, Murimwa G, Hodul PJ, Pimiento JM, Soares HP, Kim RD, Malafa MP, Hoffe SE, J Clin Oncol; GI Symposium -- American Society of Clinical Oncology, San Francisco, CA, 1/1/2017
• Impact of duodenal invasion on outcomes in patients with pancreatic cancer treated with stereotactic body radiotherapy.
  Murimwa G, Mellon EA, Frakes JM, Hodul PJ, Pimiento JM, Kim RD, Soares HP, Malafa MP, Hoffe SE, J Clin Oncol; GI Symposium -- American Society of Clinical Oncology, San Francisco, CA, 1/1/2017
• Adjuvant chemotherapy and outcomes in esophageal carcinoma.
  Saeed N, Mellon EA, Meredith KL, Hoffe SE, Shridhar R, Frakes JM, Fontaine JP, Pimiento JM, Kothari N, Almhanna K, J Clin Oncol; GI Symposium -- American Society of Clinical Oncology, San Francisco, CA, 1/1/2017
• Does metabolic tumor volume predict tumor regression grade after neoadjuvant therapy for borderline resectable pancreatic cancer?
  Jin W, Mellon EA, Hoffe SE, Frakes JM, Springett GM, Centeno BA, Kim R, Mahipal A, Pimiento JM, Malafa MP, Latifi K, American Society for Radiation Oncology, Boston, MA, 1/26/2016
• Predictors and survival for pathologic tumor response grade in borderline resectable and locally Advanced Pancreatic Cancer Treated with Induction Chemotherapy and Neo...
  Mellon EA, Hoffe SE, Frakes JM, Strom TJC, Springett GM, Shridhar R, Centeno B, Malafa MP, Hodul PJ, American Society for Radiation Oncology; GI Symposium -- American Society of Clinical Oncology, San Francisco, CA, 2016; Boston, MA, 2016, 1/26/2016
• Variability in Guidelines Effects Rates of Whole Breast Radiation Therapy Following Intraoperative Radiation Therapy.
  Mellon EA, Diaz R, Montejo ME, Laronga C, Lee MC, Hoover SJ, Khakpour N, Kubal PF, Orman A, American Society for Radiation Oncology, Boston, MA, 1/26/2016
• A patient-level meta-analysis of FOLFIRINOX for locally advanced pancreatic cancer.
  Suker M, Beumer BR, Sadot E, Marthey L, Faris JE, Mellon EA, El-Rayes B, Wang-Gillam A, Lacy J, Hosein PJ, Moorcraft SY, Conroy T, Hohla F, Allen P, Taie J, Hong TS, S..., Pancreatology, 1/1/2016
• Outcomes in patients with brain metastasis from esophageal carcinoma.
  Saeed N, Kothari N, Mellon EA, Hoffe SE, Frakes JM, Shridhar R, Pimiento JM, Meredith KL, Tran ND, Almhanna K, J Clin Oncol; GI Symposium -- American Society of Clinical Oncology, San Francisco, CA, 1/1/2016
• Predictors and survival for pathologic tumor response grade in borderline resectable and locally advanced pancreatic cancer treated with induction chemotherapy and neo...
  Mellon EA, Hoffe SE, Frakes JM, Strom TJC, Springett GM, Shridhar R, Centeno B, Malafa MP, Hodul PJ, J Clin Oncol, 1/1/2016
• A genomic framework for precision radiation therapy.
  Scott JG, Torres-Roca JF, Harrison LB, Berglund AE, Schell M, Mihaylov IB, Fulp WJ, Yue B, Welsh EA, Caudell JJ, Ahmed KA, Strom T, Mellon EA, Venkat PS, Johnstone PA,..., Int J Radiat Oncol Biol Phys; American Society for Radiation Oncology, 1/1/2016
• Post-stereotactic body radiation therapy (SBRT) neutrophil-to-lymphocyte ratio (NLR) in patients with borderline resectable pancreatic cancer (BRPC) may be a prognosti...
  Pearson AL, Jin W, Mellon EA, Frakes JM, Strom T, Springett GM, Kim R, Mahipal A, Hodul PJ, Pimiento JM, Shridhar R, Malfa MP, Hoffe SE, Int J Radiat Oncol Biol Phys; American Society for Radiation Oncology, Boston, MA, 1/1/2016
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Lectures

• Evaluation of Hyperarc SRS planning for linacs with standard and micro MLC: comparison with Gamma Knife. 
  Nashville, TN - 1/29/2018
• Spectroscopic MRI-guided Dose Escalation for GBM. 
  Fort Lauderdale, FL - 1/26/2018
• Burnout and Work-Life Balance in Radiation Oncology. 
  San Antonio, TX - 1/24/2018
• A feasibility study of radiation therapy dose escalation guided by spectroscopic MRI in patients with glioblastoma. 
  Paris, France - 1/21/2018
• Interfraction variation in stomach volume increase dose to stomach and duodenum in pancreas stereotactic body radiotherapy and is mitigated by daily adaptive magnetic ... 
  Orlando, FL - 1/6/2018
• Proposed Phase I/II trial of five fraction FSRT for large brain metastases. 
  Chicago, IL - 1/2/2018
• Magnetic Resonance Metabolic Biomarkers of CNS Malignancies. 
  William Beaumont Hospital, Royal Oak, MI - 1/15/2016
• MRI-Guided Radiation Therapy: Technology for the Next Generation of Image Guidance. 
  Crawley, England - 1/22/2015
• Favorable perioperative and survival outcomes after resection of borderline resectable pancreatic cancer treated with neoadjuvant stereotactic radiation and chemothera... 
  San Antonio, TX - 1/21/2015
• Experimental MR Techniques for Early Detection of Cancer Therapy Response. 
  Crawley, England, 2015; University of Miami Sylvester Comprehensive Cancer Center, Miami, FL, 2015 - 1/18/2015
• Stereotactic body radiation therapy (SBRT) for borderline resectable and locally advanced pancreatic cancer is effective and well tolerated. 
  Boston, MA - 1/28/2012
• In vivo NMR spectroscopy of difficult to detect metabolites. 
  University of South Florida Moffitt Cancer Center, Tampa, FL - 1/14/2011
• Mapping of cerebral oxidative metabolism with MRI. 
  Chicago, IL - 1/1/2010
• Estimation of the Regional Cerebral Metabolic Rate of Oxygen Consumption with MRI During the First 60 Seconds of 17O2 Inhalation in Swine. 
  Toronto, Ontario, Canada - 1/9/2008
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Other

• Spectroscopic MRI for dose-escalated radiation therapy. Siemens Magnetom World MReadings: MR in RT. 
  Gurbani SS, Mellon E, Weinberg B, Schreibmann E, Maudsley AA, Cooper LAD, Shu HKG, Shim H, 4th Edition ESTRO
  https://www.healthcare.siemens.com/magnetic-resonance-imaging/magnetom-world/hot-topics/mri-in-radiation-therapy
  1/1/2018
• MR-linac based radiation treatments � prospects in radiation medicine. 
  Goldwein J, Mellon EA, Elekta White Paper
  1/1/2016
• FOLFIRINOX Plus Radiation Renders Some Locally Advanced Pancreatic Cancer Patients Resectable. Magazine article. 
  Mellon EA, ASCO Post
  1/25/2015
• Pancreatic Cancer: Neoadjuvant Chemo-RT Found to Increase the Number of Patients Eligible for Life-Extending Surgery. Magazine article. 
  Mellon EA, Oncology Times
  1/23/2015
• MRI-guided radiation therapy. 
  Mellon EA, European CE Mark and FDA
• External beam radiation therapy for skin conditions. 
  Mellon EA, Strom TJ, Harrison LB, European CE Mark and FDA
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