EmmanuelKatsanisMD

PubMed

• 22 citations
  Outcomes after hematopoietic stem cell transplantation for children with I-cell disease.
  Troy C. Lund, Sara S. Cathey, Weston P. Miller, Mary Eapen, Martin Andreansky
  Biology of Blood and Marrow Transplantation. 2014-11-01
• 22 citations
  Exercise as a countermeasure for latent viral reactivation during long duration space flight
  Nadia H. Agha, Satish K. Mehta, Bridgette V. Rooney, Mitzi S. Laughlin, Melissa M. Markofski
  FASEB Journal. 2020-01-03
• 83 citations
  The immunological case for staying active during the COVID-19 pandemic.
  Richard J. Simpson, Emmanuel Katsanis
  Brain, Behavior, and Immunity. 2020-04-18

Journal Articles

• Tumor-infiltrating dendritic cells impair Treg generation.  
  Trad M, Janikashvili N, Fraszscak FE, Katsanis E, Larmonier N, Bonnotte B, (submitted)
• Tumor-derived CD4(+)CD25(+) regulatory T cell suppression of den-dritic cell function involves TGF-beta and IL-10.  
  Larmonier N, Marron M, Zeng Y, Cantrell J, Romanoski A, Sepassi M, Thompson S, Chen X, Andreansky S, Katsanis E, Cancer Immunol Immunother; 56(1):48-59. Epub 2006 Apr 13. PMID: 16612596
• Chaperone-rich cell lysate embedded with BCR-ABL peptide demonstrates enhanced anti-tumor activity against a murine BCR-ABL posi-tive leukemia.  
  Kislin KL, Marron MT, Li G, Graner MW, Katsanis E, FASEB J;21(9):2173-84. Epub 2007 Feb 27. PMID: 17327358
• A chaperone protein-enriched tumor cell lysate vaccine generates pro-tective humoral immunity in a mouse breast cancer model.  
  Li G, Andreansky S, Helguera G, Sepassi M, Janikashvili N, Cantrell J, Lacasse CL, Larmonier N, Penichet ML, Katsanis E, Mol Cancer Ther; 7(3):721-9. PMID: 18347157
• Imatinib mesylate suppresses CD4+CD25+ regulatory T cell activity and enhances ac-tive immunotherapy against BCR-ABL negative tumors.  
  Larmonier N, Janikashvili N, LaCasse C, Larmonier C, Cantrell J, Situ E, Li G, Bonnotte B, Kat-sanis E, J Immunol 181:6955-63. PMID: 18981115
• Allogeneic effector/memory Th-1 cells impair FoxP3 + regulatory T cells and synergize with chaperone-rich cell lysate vaccine to treat leukemia.  
  Janikashvili N, LaCasse C, Larmonier C, Trad M, Herrell A, Bustamante S, Har-Noy M, Larmonier N.* and Katsanis E.*, Blood;117(5):1555-64. Epub 2010 Dec 1. PMID: 2112382
• Immunological effects of rituximab on the human spleen in immune throm-bocytopenia.  
  Audia S, Samson M, Guy J, Janikashvili N, Fraszczak J, Trad M, Ciudad M, Leguy V, Berthier S, Petrella T, Aho-Glele S, Martin L, Maynadie M, Lorcerie B, Rat P, Cheyne..., Blood;118(16):4394-400. Epub 2011 Aug 29. PMID: 21876120
• T helper-1 lymphocytes induce the tumor killing function of dendritic cells by an interferon-γ-dependent mechanism.  
  LaCasse CJ, Janikashvili N, Larmonier C, Alizadeh D, Hanke NT, Kartchner J, Situ E, Centuori S, Bonnotte B, Katsanis E.* and Larmonier N.*, J Immunol;187(12):6310-7. Epub 2011 Nov 9. PMID: 22075702
• Tumor-induced myeloid-derived suppressor cells im-pair the differentiation of CD4 + CD25+ FoxP3 + regulatory T cells from naïve CD4 + CD25-FoxP3 -T lymphocytes.  
  Centuori S, Larmonier C, LaCasse CJ, Hanke NT, Kartchner J, Janikashvili N, Trad M, Alizadeh D, Bonnotte B, Larmonier N.* Katsanis E.*, J Leukoc Biol Epub 2012 Aug 13. PMID: 22891289
• The E3 SUMO ligase PIAS1 and STAT-3 cooperate to repress iNOS expression and cytotoxic activity of dendritic cells.  
  Hanke NT, LaCasse CJ, Janikashvilli N, Kartchner J, Herrell A, Larmonier C, Trad M, Bonnotte B, Katsanis E, Larmonier N, (submitted)
• Induction of BCR-ABL-specific immu-nity following vaccination with chaperone-rich cell lysates derived from BCR-ABL+ tumor cells.  
  Zeng Y, Graner MW, Thompson S, Marron M, Katsanis E, Blood;105(5):2016-22. Epub 2004 Sep 16. PMID: 15374884
• Aspects of prolactin pathophysiology in relation to prolactin secreting adenomas.  
  Tolis G, Montes J, Katsanis E, Bertrand G, Period Biol, 85(suppl 1): 29-36
• Recurrent epistaxis.  
  Am J Pediatr Hematol Oncol 1989Fall;11(3):360-7. PMID: 2675662, Pediatr Update Vol. 10, No. 12
• Immunobiology and biologic therapy of neuroblastoma. In Bertino J.R. ed.  
  Katsanis E, Ency-clopedia of Cancer, 1st ed., Academic Press, San Diego CA. 1142-1154
• Molecular chaperones: biology and prospects for pharmacol-ogical intervention.  
  Ency-clopedia of Cancer 1997, 1st ed., Academic Press, San Diego CA. 1142-1154, Pharmacol Rev; 50(4):493-514. PMID: 9860803
• The dendritic cell-regulatory T lymphocyte cross-talk contributes to tumor-induced tolerance.  
  Janikashvili N, Bonnotte B, Katsanis E, Larmonier N, Clin Dev Immunol 2011:430394. Epub 2011 Nov 3. PMID: 22110524
• Combining cancer vaccines and T lymphocyte modulation.  
  Katsanis E, Larmonier N, World Hell Biomed News 3(1):10-14
• Cytotoxic and antigen presenting functions of T helper-1-activated dendritic cells.  
  Larmonier N, Bonnotte B, Katsanis E, Oncoimmunol 1;1(4):566-568. PMID: 22754789
• Dendritic Cells for Cancer Immunotherapy.  
  Larmonier N, Katsanis E, In Emerging Trends in Cell and Gene Therapy Springer Science, New York / Heidelberg (in press)
• Interleukin-2 secretion by transduced and unselected BDL-2 lymphoma results in increased survival in mice with previ-ously established disseminated disease.  
  Orchard PJ, Katsanis E,Boyer M, May C, McIvor RS, Blazar BR, Cancer Biother Radiopharm; 11(2):155-64. PMID: 10851532
• A common hemoglobinopathy among children of Southeast Asian origin.  
  Katsanis E,Luke KH, Hsu E, Yates JR. Hemoglobin E, Can Med Assoc J;137(1):39-42. PMID: 3594333
• Prevalence and significance of mild bleeding dis-orders in children with recurrent epistaxis.  
  Katsanis E,Luke KH, Hsu E, Li M, Lillicrap D, J Pediatr;113(1 Pt 1):73-6. PMID: 3385532
• Influenza in children with cancer.  
  Kempe A, Hall CB, MacDonald NE, Foye HR, Woodin KA, Cohen HJ, Lewis ED, Gullace M, Gala CL, Dulberg CS, Katsanis E, J Pediatr 115: 33-39
• In-creased local antitumor effects of interleukin 2 liposomes in mice with MCA-106 sarcoma pul-monary metastases.  
  Anderson PM, Katsanis E,Leonard AS, Schow D, Loeffler CM, Goldstein MB, Ochoa AC, Cancer Res 15;50(6):1853-6. PMID: 2306737
• Thyroid dys-function following bone marrow transplantation: long-term follow-up of 80 pediatric patients.  
  Katsanis E,Shapiro RS, Robison LL, Haake RJ, Kim T, Pescovitz OH, Ramsay NK, Bone Marrow Transplant; 5(5):335-40. PMID: 2350628
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Abstracts/Posters

• Exogenous heat shock proteins provide adjuvant effects on enhancing the immunogenicity of apoptotic tumor cells and inducing anti-tumor im-munity.
  Feng H., Zeng Y., Graner M.W., Katsanis E, Presented at the American Association for Cancer Research, San Francisco, California
• Peptide-loaded chaperone-rich cell lysates may enhance the effectiveness of anti-cancer vaccines.
  Kislin K. L., Graner M.W., Katsanis E, American Association for Cancer Research, Orlando, Florida
• The immunosuppressive effects and biochemistry of tumor expressed albumin.
  Davis J.M., Romanoski M.A., Likhacheva A., Raymond A., Brandenberger J., Graner M.W., Kat-sanis E, Pre-sented at the American Association for Cancer Research Meeting. Proc Am Assoc Cancer Res 45:2172, Orlando, Florida
• Imatinib mesylate effectively combines with chaperone-rich cell lysate loaded dendritic cells to treat bcr-abl+ murine leukemia.
  Zeng Y., Graner M.W., Feng H., Li G., Katsanis E, Blood 102:322b
• Leukemia-derived chaperone-rich cell lysates (CRCL) provide bcr-abl specific immunity.
  Zeng Y., Graner M.W., Feng H., Katsanis E, American Society of Hematology, San Diego, California
• Tumor-derived chaperone-rich cell lysates activate dendritic cells and elicit therapeutic immunity against a wide variety of cancers.
  Graner M.W., Zeng Y., Feng H., Katsanis E, Presented at the 17 th Meeting of the Society of Biological Therapy, La Jolla, California
• Exogenous stress proteins enhance the immunogenicity of apoptotic tumor cells and stimulate anti-tumor immunity.
  Feng H., Zeng Y., Graner M.W., Likhacheva A., Katsanis E, 17 th Meeting of the Society of Biological Therapy, La Jolla, California
• Leukemia-derived chaperone-rich cell lysates acti-vate dendritic cells and elicit therapeutic immunity against murine leukemia.
  Graner M.W., Zeng Y., Feng H., Katsanis E, Presented at the 3 rd International Conference on Heat Shock Proteins in Immune Response, Farmington, Connecti-cut
• Tumor-derived multiple chaperone complexes are effective therapeutic vaccines against a variety of cancers.
  Graner M.W., Zeng Y., Feng H., Whitesell L., Katsanis E, Presented at the Cold Spring Harbor Meeting on Molecular Chaperones and the Heat Shock Response, Cold Spring Harbor, New York
• Dendritic cells loaded with tumor-derived multiple chaperone proteins enriched by free solution-isoelectric focusing induce significant protective immunity.
  Zeng Y., Feng H., Graner M.W., Katsanis E, Presented at the American Association for Cancer Research, San Francisco, Califor-nia
• Evidence for a novel, caspase 8-independent, Fas death domain-mediated apoptotic pathway.
  Feng H., Zeng Y., Graner M.W., Whitesell L., Katsanis E, Presented at the American Asso-ciation for Cancer Research, San Francisco, California
• Cytoreduction and immu-nostimulation: Properties of α-tocopheryl succinate that enhance the effectiveness of dendritic cells in treating established murine lung cancer.
  Akporiaye E., Ramanathapuram L., Kobie J.J., Katsanis E., Graner M, Presented at the American Institute for Cancer Research, Washington DC
• Tyrphostin AG1024-Mediated Inhibition of Cellular Prolif-eration and Induction of Apoptosis in Neuroblastoma Cells.
  BeliakoffJ., Katsanis E., Whitesell L, Presented at the American Associa-tion for Cancer Research, New Orleans, Louisiana
• Stressed Apoptotic Tumor Cells Express Membrane Heat Shock Proteins and Elicit Tumor Specific Immunity.
  Feng H., Zeng Y., Ramaiya K., Whitesell L., Katsanis E, Presented at the American Association for Cancer Research, New Orleans, Louisiana
• Dendritic cells mature in response to heat stressed apoptotic tumor cells and induce specific immunity in vivo.
  Zeng Y., Feng H., Whitesell L., Katsanis E, Presented at the American Associa-tion for Cancer Research, New Orleans, Louisiana
• Tumor-derived chaperone proteins as anti-cancer vaccines in multiple modality cancer therapy.
  Tyszka E., Davis N., Graner M.W., Katsanis E, Presented at the American Association for Cancer Research, New Orleans, Louisiana
• Tumor-derived multiple chaperone enrich-ment by free solution-isoelectric focusing yields potent anti-tumor vaccines.
  Graner M.W., Raymond A., Akporiaye E., Katsanis E, Presented at the 2 nd International Conference on Heat Shock Proteins in Immune Response, Farmington, Con-necticut
• Tumor-derived transforming growth factor-beta inter-feres with antigen-presenting functions of bone marrow-derived dendritic cells.
  Akporiaye E., Mack V., He L., Katsanis E, Presented at the Keystone Symposia on Cellular Immunity and Immunotherapy of Cancer, Santa Fe, New Mexico
• Augmentation of tumor lysate immunogenic-ity by enrichment of chaperone proteins using free solution isoelectric focusing.
  Katsanis E., Graner M., Raymond A., Akporiaye E, Presented at the Keystone Symposia on Cellular Immunity and Immunotherapy of Cancer, Santa Fe, New Mexico
• Successful autologous stem cell transplantation for high-risk pediatric solid tumors.
  Perentesis J., DeFor T.E., Neglia J.P., Katsanis E., Ramsay N.K, Presented at the American Society of Clinical Oncology, Atlanta, Georgia
• Busulfan and mel-phalan as preparative therapy for BMT in childhood leukemias.
  Graham M.L., Katsanis E., Shapiro T.W., Hutter J.J., Martin P., Kurtzberg J.A, Presented at the American Soci-ety of Hematology, Miami, Florida
• Chaperone-Rich Cell Lysate embedded with exogenous peptides demonstrates enhanced anti-tumor activity.
  Kislin K.L., Graner M.W., Li G., Marron M., Katsanis E, Presented at the Sixth Arizona Biosciences Research Symposium, Phoenix, Arizona
• Response of HER2+ breast cancer patients to allogeneic cell immunotherapy.
  Har-Noy M., Lausoontornsiri W., Or R., Katsanis E, J Clin Oncol 30, (suppl; abstr e13013)
• Th-1 lymphocytes promote dendritic cell tumoricidal activity.
  LaCasse C.J., Janikashvili N.,Katsanis E., Larmonier N, AACR Tumor Immunology: Basic and Clinical Advances conference, Miami, Florida
• Conversion inhibition of naive T lymphocytes into regulatory T cells by killer dentritic cells.
  Wright J., Larmonier N., Katsanis E, Journal of Investigative Medicine.  Volume: 58  Issue: 1  Page: 216,   #395
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Lectures

• Bendamustine with Total Body Irradiation Limits Murine Graft-Versus-Host Disease in Part Via Myeloid-Derived Suppressor Cells 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Chaperone rich cell lysate: Antigen, Ad-juvant, Activator. 
  Frontiers in Immunobiology and Immunopathogenesis
• Heat shock proteins as anticancer vaccines. 
  Frontiers in Medical Research Seminar
• Leukemia. 
  Pediatric Specialty Conference
• Finding your scholarship, College of Medicine. 
  Conversations with Colleagues
• Thrombocytopenias. 
  Pediatric Specialty Conference
• Clinical Updates in Oncology Symposium. 
  University of Arizona Cancer Center
• Tumor Immunology. 
  Frontiers in Medical Research Seminar
• BMT emergencies. 
  Pediatric Specialty Conference
• Bone marrow failure. 
  Pediatric Specialty Conference
• Acute Myelogenous Leukemia; chemotherapy and beyond. 
  Pediatric Grand Rounds
• Overview of stem cell transplantation. 
  Pediatric Hematology/Oncology/BMT Clinical Lecture Series
• Universal cancer vac-cine: both autologous and allogeneic. 
  Hematology Oncology Conference, University of Arizona Cancer Center
• Pediatric stem cell transplant overview. 
  Pediatric Specialty Conference
• BMT- Beware of Myths Taught - Be More Theoretical. 
  Pediatric Hematology/Oncology/BMT Clinical Lecture Series
• What oncology nurses always wanted to know about hematology but were afraid to ask. 
  Pediatric Hematology/Oncology/BMT Clinical Lecture Series
• Choosing a career in pediatric oncology. 
  College of Medicine Medical Student Hematology/Oncology Club
• Pediatric Hematology/Oncology emergencies. 
  Emergency Department Ask the Expert Series
• Phase I immu-notherapy trial for refractory leukemia. 
  Blood and Marrow Transplant Conference, University of Arizona Cancer Center
• The MD-PhD pathway. 
  Minority Access to Research Careers program
• Tumor-derived multiple chaperone complexes are effective therapeutic vaccines. 
  4th Annual Immunobiology of Cancer Workshop
• Dendritic cell based vaccines. 
  Cancer Vaccines Workshop, Tucson, Arizona
• Stress proteins and anti-tumor responses 
  Immuno-Designed Molecules (IDM) Inc, Paris, France
• Biologic therapy of cancer. 
  Grand Rounds, Phoenix Children’s Hospital, Phoenix, Arizona
• New immunobiologic ap-proaches for cancer. 
  American Society for Clinical Laboratory Science, Arizona/Nevada Division Symposium South-ern Arizon
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