Emmanuel C. Besa MD

PubMed

• 9 citations
  Spliceosome mutations are common in persons with myeloproliferative neoplasm-associated myelofibrosis with RBC-transfusion-dependence and correlate with response to po...
  Onima Chowdhury, Jennifer O'Sullivan, Nikolaos Barkas, Guanlin Wang, Gemma Buck
  Leukemia. 2021-04-01
• 21 citations
  Myelodysplastic syndromes with 5q deletion: pathophysiology and role of lenalidomide.
  Mahmoud R. Gaballa, Emmanuel C. Besa
  Annals of Hematology. 2014-03-14
• 143 citations
  Deferasirox Reduces Serum Ferritin and Labile Plasma Iron in RBC Transfusion–Dependent Patients With Myelodysplastic Syndrome
  Alan F. List, Maria R. Baer, David P. Steensma, Azra Raza, Jason Esposito
  Journal of Clinical Oncology. 2012-04-30

Journal Articles

• Hematologic problems in pregnancy. II Aplastic Anemia in pregnancy: Analysis of 5 cases and review of pertinent literature.  
  Borromeo V, Besa E, Caviles AP, Philippine Journal of Internal Medicine
• Primary adenocarcinoma of the jejunum.  
  Besa EC, Acta Medica Philippina
• Immunoadsorption of IgG molecules from the plasma of multiple myeloma and autoimmune hemolytic anemia patients. Proceedings of the Haemonetics Research Institute for A...  
  Ray PK, Idiculla A, Rhoades JE, Jr., Besa EC, Bassett JG, Cooper DR, Journal of Plasma Therapy
• Myelodysplastic syndromes: Recent advances in the biology and therapy of this complex disease.  
  Besa EC, Cancer Therapeutics
• Metastasis of an esophageal carcinoma to the soft tissue in the elbow.  
  Kumar A, Kulkarni R, Besa EC, Oncology Spectrums; Lung Cancer
• Unusually prolonged complete remission with fludarabine and cyclophosphamide followed by Rituximab in refractory, previously treated, CLL—a case report.  
  Kulkarni R, Kumar A, Besa EC, Oncology Spectrums
• Aberrant Blood Grouping Results in a Patient with Splenomegaly and Thrombocytopenia.  
  Sapanara NL, Swami V, Besa EC, Laboratory Medicine
• A Chronic Myelomonocytic Leukemia (CMML) with t(9;12)(q22;p12).  
  Mahmoodi M, Punett HH, Besa EC, Swami VK, Current Opinion in Hematology
• Deferasirox Reduces Serum Ferritin and Labile Plasma Iron in Red Blood Cell Transfusion Dependent Patients with Myelodysplastic Syndrome.  
  List AF, Baer MR, Steensma DP, Raza A, Esposito J, Martinez-Lopez N, Paley C, Feigert J, and Besa E, J Clin Oncology
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Books/Book Chapters

• Aplastic Anemia. 
  Chapter: Treatment of Refractory Anemia with Etiocholanolone and Prednisolone (Etio-Pred). Initial clinical experience 
  Page 415 - 424Gardner FH, Besa EC, Dale DC, Wolff SMEditors: S. Hibino, F, Tanaka, and N.T. Shahidi.University Park Press, Baltimore
• Hematologic Problems in Renal Disease. 
  Chapter: Sickle Cell Anemia and the Kidney 
  Page 69 - 101Besa EC, Jepson JHEditors: JH Jepson.Addison-Wiley Publishing Co, MA
• Medullary Aplasia. 
  Chapter: The Effects of Steroids and Metabolites on Bone Marrow Function 
  Page 197 - 203Gardner FH, Besa ECEditors: Y Najean.Masson Publishing USA, Inc, New York, NY
• Fundamentals of Internal Medicine. 
  Chapter: Chapter 60. Introduction to Anemia and Approach to Patients with Anemia. Chapter 61. Megaloblastic Anemia., Chapter 62. Bone Marrow Failure, Sideroblastic Anemia, and Myelophthisic Anemia 
  Page 297 - 310Besa ECEditors: D Kaye and LF Rose.C. V. Mosby Co, St Louis
• Internal Medicine for Dentistry. 
  Chapter: Chapter 60. Introduction to Anemia and Approach to Patients with Anemia. Chapter 61. Megaloblastic Anemia., Chapter 62. Bone Marrow Failure, Sideroblastic Anemia, and Myelophthisic Anemia 
  Page 311 - 323Besa ECEditors: LF Rose and D Kaye.C.V. Mosby Co, St. Louis
• Vitamins and Cancer- Human Cancer Prevention by Vitamins and Micronutrients. 
  Chapter: Clinical trials and In Vitro Studies of 13 Cis Retinoic Acid in the Myelodysplastic Syndrome 
  Page 453 - 469Besa EC, Hyzinski M, Nowell PC, Abrahm JLEditors: FL Meyskens and KN Prasad.Humana Press Inc, New Jersey
• Hematology, The National Medical Series for Independent Study. 
  Besa EC, Catalano PM, Kant JA, Jeffries LCHarwall Publishing Company, Malvern, Pennsylvania, Williams & Wilkens, Baltimore, MD
• Hematology and Coagulation, ASCP CaseSet. 
  Chapter: Myelodysplastic Syndrome, Unclassifiable, Case Studies 
  Page 370 - 375Besa EC, Kandra AEditors: G Gulati, J Filicko-O’Hara, JR Krause.
• Hematology and Coagulation, ASCP CaseSet. 
  Chapter: Paroxysmal Nocturnal Hemoglobinuria, Case Studies 
  Page 187 - 188Besa EC, Kandra AEditors: G Gulati, J Filicko-O’Hara, JR Krause.
• Taurine in Nutrition and Neurology. 
  Chapter: The Sulphur-containing Amino Acid Pathway in Normal and Malignant Cell Growth 
  Page 127 - 141Baskin SJ, Wakayama K, Knight T, Jepson JH, Besa ECEditors: RJ Huxtable and H. Pasantes-Morales.Plenum Publishing Co, New York
• Current Topics in Hematology. 
  Chapter: Physiologic Mechanisms and the Hematopoietic Effects of the Androstanes and their Derivatives 
  Page 124 - 195Gardner FH, Besa ECEditors: S Piomelli and S Yachnin.Alan R Liss Inc, New York
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Abstracts/Posters

• Medical therapy for five common cancers.
  Kim PW, Besa EC, Resident & Staff Physician
• The effect of nandrolone decanoate on the stem cell pool.
  Besa EC, Jepson JH, Gorshein D, Hait WN, Gardner FH, Clinical Research
• Rapid stem cell differentiation induced by nandrolone decanoate.
  Gorshein D, Hait WN, Besa EC, Jepson JH, Gardner FH, Proceedings of the American Association for Cancer Research; Clinical Research
• Effect of androgens on blood volumes in normal and anemic patients.
  Besa EC, Gorshein D, Gardner FH, Clinical Research
• Blood volume changes in normal and various anemic states in man following androgens.
  Besa EC, Gorshein D, Gardner FH, Annals of Internal Medicine
• Increased stem cell response to erythropoietin induced by androgens.
  Hait WN, Gorshein D, Jepson JH, Besa EC, Gardner FH, Journal of Clinical Investigation
• Effective erythropoiesis by steroid metabolites in primates.
  Besa EC, Gorshein D, Hait WN, Gardner FH, Blood
• Effect of steroid metabolites on the hematopoietic stem cell pool.
  Hait WN, Besa EC, Gorshein D, Jepson JH, Gardner FH, 15th Annual Meeting of the American Society of Hematology, Hollywood, Florida
• Effect of hyperoxia on the hematopoietic stem cell.
  Fishman DR, Leonard RA, Gorshein D, Hait WN, Besa EC, Jepson JH, Gardner FH, Clinical Research
• The effect of hyperoxia and androgen administration on erythrocyte 2,3-diphosphoglycerate level and oxygen affinity in mice.
  Gorshein D, Tyree W, Hait WN, Besa EC, Gardner FH, Delivoria-Papadopoulos M, Clinical Research
• Enhanced erythropoietic response in steroid-treated mice.
  Leonard RA, Hait WN, Gorshein D, Besa EC, Jepson JH, Gardner FH, Clinical Research
• Enhanced regeneration of erythropoietin-sensitive cells in steroid-treated mice.
  Leonard RA, Jepson JH, Gorshein D, Besa EC, Gardner FH, Clinical Research
• Stimulation and inhibition of erythropoiesis by nucleotides.
  Norris A, Gorshein D, Leonard R, Besa EC, Gardner FH, Clinical Research
• Hematopoietic stem cell damage induced by hyperoxia.
  Hait WN, Gorshein D, Fishman DR, Besa EC, Jepson JH, Gardner FH, Experimental Hematology
• A hematologic response to etiocholanolone-hydrocortisone combination in a patient with myelofibrosis.
  Besa EC, Dale DC, Gorshein D, Wolff S, Gardner FH, Clinical Research
• The role of nucleotides in erythropoiesis.
  Norris A, Besa EC, Gardner FH, Clinical Research
• Treatment of refractory anemia with etiocholanolone and prednisolone (Etio-Pred). Initial clinical experience in 8 patients.
  Besa EC, Dale DC, Wolff S, Gardner FH, Blood
• Effects of cyclic nucleotides on proliferation and differentiation of hemopoietic stem cells.
  Norris A, Besa EC, D'Silva H, Gardner FH, 18th Annual Meeting of the American Society of Hematology, Dallas, Texas
• Stimulation and inhibition of erythropoietin (ESF) production by cyclic nucleotides.
  Norris A, Besa EC, Gardner FH, Clinical Research
• Therapy of refractory anemias with Etiocholanolone-Prednisolone mixture.
  Gardner FH, Besa EC, Dale DC, Wolff S, International Symposium on Aplastic Anemia, Kyoto, Japan
• Refractory states in steroid (Androgen) induced hematopoiesis.
  Gardner FH, Besa EC, 16th International Congress of Hematology, Kyoto, Japan
• The androgen receptor in erythropoiesis. I. Studies in normal and androgen-insensitive mice.
  Besa EC, Bullock LP, Gardner FH, Bardin CW, Blood
• Comparison of erythropoietic effects of different androgen preparations on normal volunteers.
  Besa EC, Catalano PM, Gardner FH, 19th Annual Meeting of the American Society of Hematology, Boston MA
• The role of oxygen-hemoglobin affinity in the control of erythropoiesis.
  Besa EC, Pollack TW, Fisher C, Miller LD, Blood
• Prolonged remission in a case of leukemic reticuloendotheliosis (LRE) after etiocholanolone and prednisone (Etio-Pred) therapy.
  Besa EC, Gardner FH, Blood
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Lectures

• Therapeutic strategies based on new molecular concepts in myelodysplastic syndromes. 
  Central Pennsylvania Oncology Group, Harrisburg, Pennsylvania
• Repurposing HyperBlood to Run with Four Different Videodiscs. 
  University of Utah School of Medicine, Salt Lake City, Utah
• The Medical College of Pennsylvania Breast Cancer Teaching Module. 
  Philadelphia, Pennsylvania
• Designing an Integrated Self-Learning Computer Program for Effective Cancer Teaching. 
  University of Virginia School of Medicine, Charlottesville, Virginia
• Tracking Student Use of Required Computer Aided Instruction Software in Curriculum. 
  Thomas Jefferson Univarsity, Philadelphia, Pennsylvania
• Tracking Systems for Student Computer Use. 
  Burnaby, British Columbia, Canada
• You Can Lead the Horse to Water–Tracking Students’ Use of CAI. 
  Burnaby, British Columbia, Canada
• Evaluation of a computer-based learning program by a built-in tracking software using scores in quizzes and management of case-simulated patients. 
  Copenhagen, Denmark
• Bone marrow and plasma levels of all-trans-retinoic acid in normal and myelodysplastic syndrome patients. 
  American Society of Hematology 38th Annual Meeting, Orlando, Florida
• Current Status in the Treatment of Chronic Myelogenous Leukemia. 
  Plaza Hotel, MetroManila, Philippines
• Biology, Current and Investigative Therapy of Multiple Myeloma. 
  Plaza Hotel, MetroManila, Philippines
• Diagnosis and Current Management of Chronic Lymphocytic Leukemia. 
  Plaza Hotel, MetroManila, Philippines
• Early Data on a New Combination Chemotherapy Using Topotecan, Fludarabine, Ara-C, and G-CSF for Aggressive Myelodysplastic Syndromes in the Elderly. 
  5Th International Symposium on Myelodysplastic Syndromes, Prague, Czech Republic
• Prolonged survival in chronic phase chronic myelogenous leukemia (CP-CML) using maximally tolerated doses of interferon-alpha (IFN-A). 
  American Society of Clinical Oncology, 35th Annual Meeting, Atlanta, Georgia
• Which Platform to Design For? 
  University of Utah School of Medicine, Salt Lake City, Utah
• Towards a Peer-Reviewed and Updated Image and Case Bank by the American Society of Hematology. 
  Slice of Life Workshop and Computers in Healthcare Education Symposium, Salt Lake City, Utah
• An Update on Treatment of Myelodysplastic Syndrome and Transformed Leukemias. 
  Hershey Hotel, Hershey, Pennsylvania
• Topotecan, Adriamycin and Decadron (TAD) –A new combination for relapsed multiple myeloma. 
  VIIIth International Myeloma Workshop, Banff, Alberta, Canada
• Is Free and Accurate Medical Information on the Internet Possible in the New Economy? New Ways to Survive the Dot Com Age. 
  Slice of Life For Medial Multimedia Developers and Educators, University of Toronto, Toronto, Canada
• A Library of Teaching Cases for Hematology Course Directors in Case Bank of the American Society of Hematology (ASH). 
  Slice of Life For Medial Multimedia Developers and Educators, University of Toronto, Toronto, Canada
• Management of Thrombocytopenia and Update in the Treatment of Myelodysplastic Syndrome. 
  University of the Philippines – Philippine General Hospital
• Delayed Response to Lenalidomide in International Prognostic Scoring System (IPSS) Low Risk Myelodysplastic Syndrome (MDS). 
  American Society of Hematology 49th Annual Meeting & Exposition, Atlanta, GA
• Update on Treatment of Acute Myelogenous Leukemia. 
  Philippine General Hospital, University of the Philippines, College of Medicine, Manila, Philippines
• Current Perspective in the Biology and Treatment of MDS. 
  Hacettepe University, Institute of Oncology, Department of Basic Oncology, Ankara- Turkey
• Treating Serious Hematologic Malignancies in the Philippines. 
  Mandaluyong, Metro Manila, Philippines
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Other

• Polycythemia, Secondary. 
  Besa, EC and Woermann U, EMedicine from Web MD
  http://emedicine.medscape.com/article/205039-overview
• Myelodysplastic Syndrome. 
  Besa, EC and Woermann U, EMedicine from Web MD
  http://emedicine.medscape.com/article/207347-overview
• Paroxysmal Nocturnal Hemoglobinuria. 
  Besa, EC and Woermann U, EMedicine from Web MD
  http://emedicine.medscape.com/article/207347-overview
• Bone Marrow Failure. 
  Besa, EC and Woermann U, EMedicine from Web MD
  http://emedicine.medscape.com/article/199003-overview
• Polycythemia Vera. 
  Besa, EC and Woermann U, EMedicine from Web MD
  http://emedicine.medscape.com/article/205114-overview
• Chronic Myeloid Leukemia. 
  Besa, EC and Woermann U, EMedicine from Web MD
  http://emedicine.medscape.com/article/204647-overview
• Myelophthisic Anemia. 
  Besa, EC and Woermann U, EMedicine from Web MD
  http://emedicine.medscape.com/article/204647-overview
• Hairy Cell Leukemia. 
  Besa, EC and Woermann U, EMedicine from Web MD
  http://emedicine.medscape.com/article/200580-overview
• Acute Promyelocytic Leukemia. 
  Besa, EC and Woermann U, EMedicine from Web MD
  http://emedicine.medscape.com/article/1495306-overview
• Chronic Myelogenous Leukemia. 
  Besa EC
  http://emedicine.medscape.com/article/199425-overview
• Paroxysmal Nocturnal Hemoglobinuria. 
  Besa EC
  http://emedicine.medscape.com/article/207468-overview
• Secondary Polycythemia. 
  Besa EC
  http://emedicine.medscape.com/article/205039-overview
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