Elizabeth Rachel Seaquist MD

Endocrinology•Minneapolis, MN

Diabetes, Lipid Metabolism

Professor, Medicine, University of Minnesota Medical School

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909 Fulton Ave SEM Health FairviewMinneapolis, MN 55455
Phone+1 612-625-8690

Education & Training

University of MinnesotaFellowship, Endocrinology, Diabetes, and Metabolism, 1985 - 1989
University of MinnesotaResidency, Internal Medicine, 1983 - 1985
University of MinnesotaInternship, Internal Medicine, 1982 - 1983
University of Minnesota Medical SchoolClass of 1982

Certifications & Licensure

MN State Medical License 1983 - 2025
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Endocrinology, Diabetes and Metabolism

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013
Super Doctor SuperDoctors.com

Clinical Trials

Measurement of Glucose/Glycogen Metabolism in Humans Using Magnetic Resonance at 4 or 7 Tesla Start of enrollment: 2004 Dec 01
Completed
Phase 2
Measurement of Glucose Metabolism in Humans Using Magnetic Resonance at 4 Tesla. Substudy: Hypoglycemia Unawareness Start of enrollment: 2007 Dec 01
Completed
Naltrexone and Hypoglycemia in Type 1 Diabetes Start of enrollment: 2009 Oct 01
Completed
Phase 1, Phase 2
A Comparative Effectiveness Study of Major Glycemia-lowering Medications for Treatment of Type 2 Diabetes Start of enrollment: 2013 May 01
Completed
Phase 3
Restoration of Retinal Vascular Responses in Type 1 Diabetic Patients Start of enrollment: 2016 Jul 01
Completed
Phase 1
PK/PD Study of U-500 Regular Insulin Start of enrollment: 2015 Jul 01
Completed
Phase 2
Clinical Usability of Intranasal Glucagon in Treatment of Hypoglycemia Start of enrollment: 2014 May 01
Completed
Phase 3
A Randomized Double Blinded Study to Examine the Use of N-acetyl Cysteine for the Prevention and Treatment of HAAF in Patients With Type 1 Diabetes Start of enrollment: 2015 Feb 01
Completed
Phase 1, Phase 2
Cerebral Responses to Insulin Induced Hypoglycemia Start of enrollment: 2004 Jan 01
Completed
Not Applicable
Naloxone, Hypoglycemia and Exercise Start of enrollment: 2017 Sep 18
Completed
Phase 2
Recurrent Hypoglycemia in Type 1 Diabetes (Aim 1) Start of enrollment: 2018 May 24
Completed
Not Applicable
Recurrent Hypoglycemia in Type 1 Diabetes (Aim 2) Start of enrollment: 2020 Aug 12
Active, not recruiting
Not Applicable
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Publications & Presentations

PubMed

2 citations
Development and Validation of an Electronic Health Record-Based Risk Assessment Tool for Hypoglycemia in Patients With Type 2 Diabetes Mellitus.
Sisi Ma, Alison Alvear, Pamela J Schreiner, Elizabeth R Seaquist, Thomas Kirsh
Journal of Diabetes Science and Technology. 2025-01-01
6 citations
Association of Baseline Factors With Glycemic Outcomes in GRADE: A Comparative Effectiveness Randomized Clinical Trial.
W Timothy Garvey, Robert M Cohen, Nicole M Butera, Erin J Kazemi, Naji Younes
Diabetes Care. 2024-04-01
1 citations
Nasal Glucagon Reverses Insulin-induced Hypoglycemia With Less Rebound Hyperglycemia: Pooled Analysis of Clinical Trials.
Elizabeth Seaquist, Marga Giménez, Yu Yan, Munehide Matsuhisa, Christi Yuting Kao
Journal of the Endocrine Society. 2024-02-19

Lectures

Hypoglycemia in Diabetes
ENDO 2018: 100th Endocrine Society Annual Meeting - Chicago, Illinios - 03/18/2018
Naltrexone for Treatment of Hypoglycemia Unawareness in Type 1 Diabetes: A Randomized Clinical Trial
Minneapolis, MN - 6/16/2014
President, Medicine & Science Address--Stop Diabetes--It's Up to Us
Elizabeth R. Seaquist, MD - 6/15/2014
Hippocampal Neurochemical Profile of Subjects with Type 1 Diabetes (T1D) as Measured by ¹H - Magnetic Resonance Spectroscopy (MRS)
Minneapolis, MN - 6/15/2014
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Press Mentions

New Clinical Practice Guideline Offers Recommendations to Manage Hypoglycemia in People with DiabetesDecember 7th, 2022
Counting Covid-19 Cases Doesn’t Capture the Pandemic’s ImpactJanuary 26th, 2022
U.S. Death Rate Soared 17% in 2020, Final CDC Mortality Report ConcludesDecember 22nd, 2021
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Grant Support

University of Minnesota Clinical Center for the Restoration of Impaired Awareness of Hypoglycemia in Type 1 DiabetesUNIVERSITY OF MINNESOTA2022–2027
Markers Of Beta Cell Dysfunction And Hypoglycemia In AccordNational Institute Of Diabetes And Digestive And Kidney Diseases2011
Measurement Of Glucose Homeostasis In Human Brain By NMRNational Center For Research Resources2009–2011
Measurement Of Glucose Homeostasis In Human Brain By NMRNational Institute Of Neurological Disorders And Stroke1997–2011
Training Grant In Diabetes Endocrinology &MetabolismNational Institute Of Diabetes And Digestive And Kidney Diseases2008–2010
Measurement Of Glucose In Human Brain By NMR: The Effect Of Islet Cell TransplanNational Center For Research Resources2009
Measurement Of Glucose Homestatsis In Human Brain By NMRNational Institute Of Neurological Disorders And Stroke2006–2009
NMR Measurements Of Human Brain Glycogen MetabolismNational Center For Research Resources2006–2009
In Vivo Magnetic Resonance Studies Of Glucose Metabolism In Humans At 4 Tesla USNational Center For Research Resources2006–2009
Endocrine Pancreatic Function In Recipients Of Pancreas Islet TxNational Center For Research Resources2004–2009
Action To Control Cardiovascular Risk In Diabetes (ACCORD)National Center For Research Resources2004–2009
Insulin Redu BOLD RESP But Is W/O Effect On The VEP Of A Visual TASK In HumanNational Center For Research Resources2008
White Matter Structure/Function In DiabetesNational Center For Research Resources2006–2008
Brain Glucose Transport In Subjects &Patients With Diabetes Following HypoglycNational Center For Research Resources2005–2008
Cerebral Responses To Insulin-Induced Hypoglycemia-Aim 3National Center For Research Resources2006–2007
Cerebral Responses To Insulin-Induced Hypoglycemia-Aims 1 &2National Center For Research Resources2005–2006
Cerebral Responses To Insulin-Induced Hypoglycemia-Aim 4National Center For Research Resources2005–2006
Cerebral Responses To Insulin-Induced HypoglycemiaNational Institute Of Diabetes And Digestive And Kidney Diseases2002–2006
NMR Studies Of Human Brain Glucose MetabolismNational Center For Research Resources2004–2005
The Effect Of Recurrent Hypoglycemia On Cerebral Glucose MetabolismNational Center For Research Resources2004
Cerebral Responses To Insulin-Induced HypoglycemiaNational Center For Research Resources2004
Pancreas &Islet Transplantation In HumansNational Center For Research Resources2001–2002
Pancreas Transplantation--Endocrin Pancreatic Function In Recipients And DonorsNational Center For Research Resources1998–2002
In Vivo Magnetic Resonance (MR) Studies Of Glucose Metabolism In HumansNational Center For Research Resources1996–2002
Use Of Hypoglycemic Clamp In Assessment Of Pituitary FunctionNational Center For Research Resources1998–2000
Genetic Markers In Families With Maturity Onset Diabetes Of YouthNational Center For Research Resources1996–1999
Neural Regulation Of Glucagon SecretionNational Center For Research Resources1996–1997
Glucose Transport In Human BrainNational Center For Research Resources1996
PGE2, G Proteins, And Insulin SecretionNational Institute Of Diabetes And Digestive And Kidney Diseases1989–1993
Assessment Of CAMP In Glucose-Induced Insulin SecretionNational Institute Of Diabetes And Digestive And Kidney Diseases1988