ElineTLuning PrakMD

PubMed

• 66 citations
  Tissue adaptation and clonal segregation of human memory T cells in barrier sites.
  Maya M L Poon, Daniel P Caron, Zicheng Wang, Steven B Wells, David Chen
  Nature Immunology. 2023-02-01
• 138 citations
  Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases
  Yun Li, Jin Li, Sihai Dave Zhao, Jonathan P. Bradfield, Frank D. Mentch
  Nature Medicine. 2015-09-08
• 128 citations
  B lymphocyte-directed immunotherapy promotes long-term islet allograft survival in nonhuman primates.
  Chengyang Liu, Hooman Noorchashm, Jennifer A. Sutter, Mina Naji, Eline T. Luning Prak
  Nature Medicine. 2007-11-01

Journal Articles

• B cell development in chromosome 22q112 deletion syndrome  
  Derfalvi, B., Maurer, K., McDonald, D.M., Zackai, E., Meng, W., Luning Prak, E.T. and K.E. Sullivan, Clinical Immunology, 1/1/2016
• Invited Review: the analysis of clonal expansions in normal and autoimmune B cell repertoires  
  Uri Hershberg and Eline T. Luning Prak, Phil. Trans. B, 1/1/2015
• Can immune thrombocytopenia be cured with medical therapy?  
  Cuker, A., Luning Prak, E.T. and D. B. Cines, Seminars in Thrombosis and Hemostasis, 1/1/2015
• Impaired receptor editing and heterozygous RAG2 mutation in a patient with systemic lupus erythematosus  
  Walter, J.E., Lo, M., Kis-Toth, K., Tirosh, I., Frugoni, F., Lee, Y.N., Abraham, R.S., Chen, K., Pillai, S., Dunham, J., Tsokos, G., Luning Prak, E.T. and L.D. Notaren..., Journal of Allergy and Clinical Immunology, 1/1/2015
• Genetic Sharing and Heritability of Pediatric Age of Onset Autoimmune Diseases  
  Li, Y.R., Zhao, S., Mohebnasab, M., Li, J., Bradfield, J., Steel, L., Abrams, D., Kobie, J., Mentch, F., Glessner, J., Guo, Y., Wei, Z., Cardinale, C., Bakay, M., Conn..., Nature Communications, 1/1/2015
• Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases  
  Li, Y.R., Li, J., Zhao, S.D., Bradfield, J.P., Mentch, F.D., Maggadottir, S.M., Hou, C., Abrams, D.J., Chang, D., Gao, F., Guo, Y., Wei, Z., Connolly, J.J., Cardinale,..., Nature Medicine, 1/1/2015
• Altered BCR and TLR signals promote enhanced positive selection of autoreactive transitional B cells in Wiskott-Aldrich Syndrome  
  Kolhatkar, N.S., Brahmandam, A., Thouvenel, C., Becker-Herman, S., Jacobs, H.M., Schwartz, M.A., Khim, S., Panigrahi, A.K., Luning Prak, E.T., Thrasher, A.J., Notarang..., Journal of Experimental Medicine, 1/1/2015
• RAG2 mutants alter DSB repair pathway choice in vivo and illuminate the nature of "alternative NHEJ"  
  V. Gigi, S. Lewis, O. Shestova, M. Mijuskovic, L. Deriano, W. Meng, E. T. Luning Prak and D. B. Roth, Nucleic Acids Research, 1/1/2014
• DH reading frame usage in the expressed human antibody repertoire is selected based upon amino acid content  
  . Benichou, J., Glanville, J., Luning Prak, E.T., Azran, R., Kuo, T.C., Pons, J., Desmarais, C., Tsaban, L. and Y. Louzoun, J. Immunol, 1/1/2013
• Improvement in beta-cell secretory capacity following human islet transplantation according to the CIT07 protocol  
  Rickels, M., Liu, C., Shlansky-Goldberg, R., Soleimanpour, S., Vivek, K., Kamoun, M., Min, Z., Markmann, E., Palangian, M., Dalton-Bakes, C., Fuller, C., Chiou, A., Ba..., Diabetes, 1/1/2013
• Antibodies that bind complex glycosaminoglycans accumulate in the golgi  
  Radic, M., Weigert, M., Khan, S.N., Han, J., Kalinina, O. and E.T. Luning Prak, Proc Natl Acad Sci USA, 1/1/2013
• TLR9 Promotes Tolerance by Restricting Survival of Anergic Anti-DNA B Cells Yet is Also Required for Their Activation  
  Nickerson, K.M., Christensen, S.R., Cullen, J.L., Meng, W., Luning Prak, E. T. and M. J. Shlomchik, J. Immunol, 1/1/2013
• Rituximab Therapy for Primary Sjogren's Syndrome: An Open-Label Clinical Trial and Mechanistic Analysis  
  St. Clair, E.W., Levesque, M.C., Luning Prak, E.T., Vivino, F.B., Alappatt, C.J., Spychala, M.E., Wedgwood, J., McNamara, J., Moser Sivils, K.L., Fisher, L. and P. Cohen, Arthritis and Rheumatism, 1/1/2013
• Global analysis of B cell selection using an immunoglobulin light chain-mediated model of autoreactivity  
  Andrews, S., Zhang, Q., Lim, S., Li, L., Lee, J-H, Zheng, N. Y., Huang, M., Taylor, W., Farris, A. D., Ni, D., Meng, W., Luning Prak, E. T. and P. Wilson, Journal of Experimental Medicine, 1/1/2013
• Altered B cell homeostasis is associated with Type I diabetes and carriers of the PTPN22 allelic variant  
  Habib, T., Funk, A., Rieck, M., Brahmandam, A., Dai, X., Panigrahi, A., Luning Prak, E., Meyer-Bahlburg, A., Sanda, S., Greenbaum, C., Rawlings, D. and J. Buckner, J. Immunol, 1/1/2012
• Restoring balance to B cells in ADA deficiency  
  Eline T. Luning Prak, J. Clin. Invest. Kathryn Claiborn, 1/1/2012
• Lenalidomide therapy in treatment refractory cutaneous lupus erythematosus: Histologic and circulating leukocyte profile and potential risk of a systemic lupus flare  
  Braunstein, I., Goodman, N.G., Rosenbach, M., Okawa, J., Shah, A., Krathen, M., Kovarik, C., Luning Prak, E.T. and V.P. Werth, Journal of the American Academy of Dermatology, 1/1/2012
• Adoptive transfer of autologous T cells improves T cell repertoire diversity and long-term B-cell function in pediatric patients with neuroblastoma  
  Grupp, S.A., Luning Prak, E.T., Boyer, J., McDonald, K.R., Shusterman, S., Thompson, E., Callahan, C., Jawad, A.F., Levine, B.L., June, C.H. and K.E. Sullivan, Clinical Cancer Research, 1/1/2012
• Sullivan: Rituximab-treated patients have a poor response to influenza vaccination  
  Eisenberg, R.A., Jawad, A.F., Boyer, J., Maurer, K., McDonald, K., Luning Prak, E.T. and K.E, J. Clin. Immunol, 1/1/2012
• B-cell tolerance defects in the B6Aec1/2 mouse model of Sjogren's syndrome  
  Meng, W., Li, Y., Xue, E., Satoh, M., Peck, A.B., Cohen, P.L., Eisenberg, R.A. and E. T. Luning Prak, Journal of Clinical Immunology, 1/1/2012
• B cell receptor editing in tolerance and autoimmunity  
  E. Luning Prak, M. Monestier and R. A. Eisenberg, Annals of the New York Academy of Sciences The Year in Immunology, 1/1/2011
• Transfer of Influenza Vaccine-Primed Co-stimulated Autologous T-Cells after Stem Cell Transplantation for Multiple Myeloma Leads to Reconstitution of Influenza Immunit...  
  Transfer of Influenza Vaccine-Primed Co-stimulated Autologous T-Cells after Stem Cell Transplantation for Multiple Myeloma Leads to Reconstitution of Influenza Immunit..., Blood, 1/1/2011
• Hypersensitivity to rabbit anti-thymocyte globulin in an islet transplant recipient: a case report  
  Rickels, M., Soleimanpour, S., Sekiguchi, D., LaRosa, D., Luning Prak, E. and A. Naji, Transplantation Proceedings, 1/1/2011
• Alternative Mechanism of Receptor Editing in Autoreactive B cells  
  O. Kalinina, C. Doyle-Cooper, J. Miksanek, W. Meng, E. Luning Prak and M. Wiegert, Proc. Natl. Acad. Sci. U.S.A, 1/1/2011
• Analysis of B cell subsets following pancreatic islet cell transplantation in a patient with type 1 diabetes by cytometric fingerprinting  
  Debora R. Sekiguchi, Jennifer A. Sutter, Michael R. Rickels, Ali Naji, Chengyang Liu, Kathleen J. Propert, Wade T. Rogers and Eline T. Luning Prak, J. Immunol. Methods, 1/1/2011
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Books/Book Chapters

• Arthritis Research and Therapy 
  Chapter: Persistence and selection of an expanded B cell clone in the setting of rituximab therapy for Sjogren's syndrome 
  Hershberg, U., Meng, W., Zhang, B., Haff, N., St. Clair, EW, Cohen, PL, McNair, PD, Li, L, Levesque, MC and ET Luning PrakEditors: Peter Lipsky.BioMed Central2014
• Frontiers in Immunology 
  Chapter: Trials and Tribulations with VH Replacement 
  W. Meng, S. Jayaraman, B. Zhang, G.W. Schwartz, R. Daber, U. Hershberg, A. Garfall, C. Carlson and E. T. Luning PrakEditors: Jason Zhang.Frontiers Medicine and Engineering2014
• Clinical Transplantation 
  Chapter: Antibody-mediated rejection in heart transplant recipients: potential efficacy of B cell depletion and antibody removal 
  Page 489 - 496Charlene Bierl, Barry Miller, Eline T. Luning Prak, Alison Gasiewski, Jane Kearns, Mariell Jessup and Malek KamounEditors: Terasaki.2006
• Clinical Transplants 
  Chapter: B cell monitoring of transplant patients treated with anti-CD20 
  Page 427 - 437Khaled O. Abdallah and Eline T. Luning PrakEditors: Terasaki.2006
• The Handbook of Transfusion Medicine 
  Chapter: Approach to the Platelet-Refractory Patient 
  Page 209 - 219Luning Prak, EAcademic Press, San Diego, CA2001
• Essentials of Basic Science in Surgery 
  Chapter: Nutrition. Essentials of Basic Science 
  Page 384 - 390Luketich, J. , D. Rigberg and E. Luning PrakEditors: Savage, Fishman and Miller.J.B. Lippincott & Co., Philadelhpia, PA1993
• Essentials of Basic Science in Surgery 
  Chapter: Biochemistry of Metabolism 
  Page 7 - 24Luketich, J. and E. Luning PrakEditors: Savage, Fishman and Miller.J.B. Lippincott & Co, Philadelhpia, PA1993
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Lectures

• B cells, antibodies and antibody repertoires 
  1/1/2016
• Antibody repertoire profiling in health and disease 
  Philadelphia, PA - 1/1/2015
• B cell autoimmunity 
  Spring House, PA - 1/1/2015
• Immunodiagnostic lab testing and implications for the rheumatologist 
  Philadelphia, PA - 1/1/2015
• B cell development and antibody production 
  Spring House, PA - 1/1/2014
• Genetics of the antibody repertoire in autoimmunity 
  Luebbeck, Germany - 1/1/2013
• Persistence and selection of an expanded B cell clone in the setting of rituximab therapy for Sjogren's Syndrome 
  Philadelphia, PA - 1/1/2013
• Advances in Targeting of B cell Survival Factors 
  Washington, DC - 1/1/2012
• Lymphocyte subset profiling in patients with autoimmunity 
  1/1/2011
• B cell tolerance checkpoints 
  Philadelphia, PA - 1/1/2011
• Immunology Studies on CIT patients at the University of Pennsylvania 
  Washington, DC - 1/1/2011
• Systemic Lupus Erythematosus: that's how B cells lose tolerance! 
  1/1/2007
• CAMB 510 
• High throughput sequencing of antibody genes 
  Philadelphia, PA
• CAMB510 B cell tolerance and autoimmunity 
• Laboratory Measurements course directed by Bruce Sachais 
• B-cell development and antibodies 
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