Efrat Dotan MD

Oncology•Philadelphia, PA

Gastrointestinal Cancer, Hematologic Oncology

Executive Medical Director Penn Medicine Ann B Barshinger Cancer Institute

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333 Cottman Ave# FoxPhiladelphia, PA 19111
Phone+1 215-728-6900
Fax+1 215-728-3639

Summary

I specialize in treatment of patients with gastrointestinal cancers with various chemotherapies. My goal is to provide each patient with cutting age therapy for therapy for their cancer, and supportive care necessary for tolerating treatment. I am specifically interested in caring for older adults with gastrointestinal cancers, while focusing on other factors that are not related to their cancer and complicates their care.

Education & Training

Temple University Hospital-Fox Chase Cancer CenterFellowship, Hematology and Medical Oncology, 2007 - 2010
Zucker School of Medicine at Hofstra/Northwell at Lenox Hill HospitalResidency, Internal Medicine, 2003 - 2006
Technion-Israel Inst of Technology Faculty of MedicineClass of 2002

Certifications & Licensure

PA State Medical License 2007 - 2026
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013

Clinical Trials

Chemoembolization Using Irinotecan in Treating Patients With Liver Metastases From Metastatic Colon or Rectal Cancer Start of enrollment: 2010 Oct 01
Terminated
Phase 1
The Hurria Older PatiEnts (HOPE) With Breast Cancer Study Start of enrollment: 2011 Sep 09
ACTIVE_NOT_RECRUITING
Study of Labetuzumab Govitecan in Participants With Metastatic Colorectal Cancer Start of enrollment: 2013 Feb 12
Terminated
Phase 1, Phase 2
Telomere Length in Predicting Toxicity in Older Patients With Stage III-IV Colorectal Cancer Undergoing Chemotherapy Start of enrollment: 2013 Oct 01
Terminated
Dose Escalation Study of OMP-54F28 in Combination With Nab-Paclitaxel and Gemcitabine in Patients With Previously Untreated Stage IV Pancreatic Cancer Start of enrollment: 2013 Nov 01
Completed
Phase 1
Irinotecan-Eluting Beads in Treating Patients With Refractory Metastatic Colon or Rectal Cancer That Has Spread to the Liver Start of enrollment: 2016 Jan 29
Terminated
Phase 1
Regorafenib in Metastatic Colorectal Cancer
COMPLETED
PHASE2
Improving the Approach to and Management of the Older Metastatic Breast Cancer Patient Start of enrollment: 2016 Nov 01
Completed
Not Applicable
Comparing Two Treatment Combinations, Gemcitabine and Nab-Paclitaxel With 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan for Older Patients With Pancreatic Cancer That Has Spread Start of enrollment: 2020 Aug 26
ACTIVE_NOT_RECRUITING
PHASE2
Improving the Approach to and Management of the Older Patient With Metastatic Gastric Cancer Start of enrollment: 2020 Sep 22
Recruiting
Not Applicable
Roles: Principal Investigator, Contact
PHL Treatment in Pancreatic Cancer Start of enrollment: 2021 Oct 20
RECRUITING
EARLY_PHASE1
Roles: Contact, Principal Investigator
Redefining FOLFIORINOX in Older Pancreatic Cancer Patients Start of enrollment: 2022 Apr 22
RECRUITING
PHASE2
Roles: Principal Investigator, Contact
A Study to Evaluate KIN-3248 in Participants With Advanced Tumors Harboring FGFR2 and//or FGFR3 Gene Alterations Start of enrollment: 2022 Apr 18
Active, not recruiting
Phase 1
Roles: Contact
A Study of CTX-009 in Combination With Paclitaxel in Adult Patients With Unresectable Advanced, Metastatic or Recurrent Biliary Tract Cancers (COMPANION-002) Start of enrollment: 2023 Jan 09
ACTIVE_NOT_RECRUITING
PHASE2, PHASE3
Roles: Contact, Principal Investigator
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Publications & Presentations

PubMed

Oncology: What You May Have Missed in 2024.
Zainab Ali Amer Al Maqrashi, Sze Wah Samuel Chan, Zeba Siddiqui, Efrat Dotan
Annals of Internal Medicine. 2025-04-01
"Start low, go slow," a strategy to tailor treatment dosing in older or vulnerable adults with advanced solid cancer: A systematic review and meta-analysis.
Gabriel Aleixo, Tej Patel, Julianne Ani, Will J Ferrell, Efrat Dotan
Journal of Geriatric Oncology. 2025-03-01
Racial/Ethnic Differences and Effects of Clinical/Socioeconomic Factors on Time from Diagnosis to Treatment in Pancreatic Cancer.
Anush Sridharan, Efrat Dotan, Marianna Dorta, Navya Vemula, Elizabeth Handorf
Journal of Gastrointestinal Cancer. 2025-02-15

Press Mentions

Geriatric Assessment, QoL Correlate with OS in Older Patients with Pancreatic CancerJanuary 26th, 2025
Penn Medicine Names New Cancer Institute LeaderNovember 15th, 2024