Edward Lewis Tobinick MD

PubMed

• Perispinal etanercept stroke trial design: PESTO and beyond.
  Edward Tobinick, Danielle Ucci, Kirsten Bermudo, Samantha Asseraf
  Expert Opinion on Biological Therapy. 2024-10-01
• 11 citations
  Rapid improvement in severe long COVID following perispinal etanercept.
  Edward Tobinick, Robert N Spengler, Tracey A Ignatowski, Manar Wassel, Samantha Laborde
  Current Medical Research and Opinion. 2022-12-01
• 7 citations
  Immediate Resolution of Hemispatial Neglect and Central Post-Stroke Pain After Perispinal Etanercept: Case Report
  Edward L Tobinick
  Clinical Drug Investigation. 2020-01-01

Journal Articles

• Immediate neurological recovery following perispinal etanercept years after brain injury  
  Tobinick E, Rodriguez-Romanacce H, Levine A, Ignatowski TA, Spengler RN, Clinical Drug Investigation, 1/1/2014
• The Cerebrospinal Venous System: Anatomy, Physiology, and Clinical Implications  
  Tobinick E, Medscape General Medicine, 1/1/2006
• TNF Modulation for Treatment of Alzheimer’s Disease: A Six Month Pilot Study  
  Edward Tobinick MD, H. Gross MD, A. Weinberger MD, H. Cohen MD FRCPC, Medscape General Medicine, 1/1/2006
• Rapid intracerebroventricular delivery of 64-Cu-DOTA-etanercept after peripheral administration demonstrated by PET imaging  
  Tobinick E, K Chen, X. Chen, BMC Research Notes, 1/27/2009
• Perispinal etanercept: a new therapeutic paradigm in neurology  
  Tobinick E, Expert Review of Neurotherapeutics, 1/1/2010
• Perispinal etanercept for post-stroke neurological and cognitive dysfunction: scientific rationale and current evidence.  
  Ignatowski TA, Spengler RN, Dhandapani KM, Folkersma H, Butterworth RF, Tobinick E., CNS Drugs, 8/1/2014
• Authors’ reply to Whitlock: Perispinal etanercept for post-stroke neurological and cognitive dysfunction:scientific rationale and current evidence  
  Ignatowski TA, Spengler RN, CNS Drugs, 1/1/2014
• Author’s reply to Page: “Selective TNF inhibition for chronic stroke and traumatic brain injury: an observational study involving 629 consecutive patients treated with...  
  Tobinick E, CNS Drugs, 1/1/2013
• New hope for survivors of stroke and traumatic brain injury  
  Clark, I., CNS Drugs, 1/1/2012
• Beneficial neurological effects observed in a patient with psoriasis treated with etanercept  
  Bassi, E. and C. De Filippi, Am J Clin Dermatol, 1/1/2010
• Perispinal etanercept for neuroinflammatory disorders  
  Tobinick E, Drug Discovery Today, 1/1/2009
• Tumor necrosis factor modulation for treatment of Alzheimer’s disease: rationale and current evidence  
  Tobinick E, CNS Drugs, 1/1/2009
• The value of drug repositioning in the current pharmaceutical market  
  Tobinick E, Drug News and Perspectives, 1/1/2009
• Rapid cognitive improvement in Alzheimer’s disease following perispinal etanercept administration  
  Edward Tobinick, Hyman Gross, J Neuroinflammation, 1/9/2008
• Rapid improvement in verbal fluency and aphasia following perispinal etanercept in Alzheimer’s disease  
  Edward Tobinick, Hyman Gross, BMC Neurology, 1/1/2008
• P4-266: Modification of synaptic plasticity by TNF and sphingomyelinase: Implications for cognitive impairment in Alzheimer’s disease  
  Wang, Y., Alzheimer’s and Dementia, 1/1/2008
• Perispinal etanercept: potential as an Alzheimer therapeutic  
  Griffin, W.S., J Neuroinflammation, 1/1/2008
• Perispinal administration of anti-TNF agent results in rapid cognitive improvement in AD  
  Tobinick E, Nature Clinical Practice Neurolgy, 1/1/2008
• New horizons in the treatment of Alzheimer’s disease: Immunotherapeutics  
  Tobinick E, US Neurology, 1/1/2008
• Paradigm Shift: Excess TNF-alpha emerges as a key therapeutic target in Alzheimer’s disease  
  Tobinick E, Medscape General Medicine, 1/1/2007
• Resolution of chronic pain and fingertip ulceration due to hand-arm vibration syndrome following combination pharmacotherapy  
  Buell, C., E. Tobinick, K. Lamp, H, Arch Derm, 1/1/2007
• Perispinal etanercept for treatment of Alzheimer’s disease  
  Tobinick E, Current Alzheimer Research, 1/1/2007
• Spinal delivery of p38 and TNF-alpha inhibitors  
  Buell, C., E. Tobinick, K. Lamp, H, PLoS Medicine, 1/1/2006
• Efficacy of etanercept delivered by perispinal administration for chronic back and/or neck disc-related pain: a study of clinical observations in 143 patients  
  Edward Tobinick, MD, et. al., Current Medical Research and Opinion, 1/1/2004
• Perispinal TNF-alpha inhibition for discogenic pain  
  Edward Tobinick, MD, et. al., Swiss Med W, 1/1/2003
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Books/Book Chapters

• Skin Surgery, A Practical Guide 
  Usatine R, Tobinick E, Moy R,Siegel DMosby1998

Abstracts/Posters

• TNF modulation for treatment of Alzheimer’s disease
  Tobinick E, Inaugural Targeting Alzheimer’s with Novel Therapeutics Conference at the World Pharmaceutical Congress, Philadelphia, PA, 1/11/2009
• Perispinal etanercept produces rapid improvement in primary progressive aphasia
  Tobinick E, 11th International Conference on Alzheimer’s Disease, Chicago, IL, 1/30/2008
• TNF Modulation for Treatment of Alzheimer’s Disease: Effects on Verbal Function
  Tobinick E, Shirinyan D, Gross H, Days of Molecular Medicine Conference, Karolinska Institutet, Stockholm, Sweden, 1/27/2006
• Perispinal TNF-alpha inhibition for discogenic pain
  Tobinick E, 2nd Annual Restauracion Neurologica 2004 International Conference, Havana, Cuba, 1/27/2004
• Perispinal etanercept for Alzheimer’s Disease
  Tobinick E, Restauracion Neurologica 2009 International Conference, Havana, Cuba, 1/11/2009
• TNF antagonists for neurological disorders: from concept to the clinic
  Tobinick E, GTC bio’s 5th Modern Drug Discovery & Development Conference, San Diego, CA, 1/14/2009
• Neuroinflammation as a new therapeutic target in neurology
  Tobinick E, Medical Staff CME Lecture, University Hospital, Tamarac, FL, 1/10/2011
• Repurposing of Enbrel for Alzheimer’s Disease
  Tobinick E, Third Annual Drug Repositioning Summit, Boston, MA, 1/6/2008
• Perispinal etanercept for treatment of Alzheimer’s Disease
  Tobinick E, 7th International Conference on Alzheimer’s Disease Drug Discovery; Best Practices in the Continuum of Care: Advances in Alzheimer’s Disease Management conference, University of Arkansas for Medical Sciences, Little Rock, AR, 2008, 1/1/2008
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Lectures

• TNF inhibition for aphasia after stroke or brain injury 
  Fort Lauderdale, FL - 1/30/2015