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Office
5600 Nathan Shock Dr
Baltimore, MD 21224Phone+1 410-558-8202Fax+1 410-558-8150
Education & Training
- Johns Hopkins UniversityResidency, Internal Medicine, 1975 - 1976
- MedStar Health/Georgetown-Washington Hospital CenterFellowship, Cardiovascular Disease, 1974 - 1975
- University of RochesterResidency, Internal Medicine, 1970 - 1972
- Georgetown University School of MedicineClass of 1970
Certifications & Licensure
- MD State Medical License 1973 - 2026
- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Cardiovascular Disease
Awards, Honors, & Recognition
- Elected Member The American Society for Clinical Investigation, 1984
Clinical Trials
- Vascular Aging: The Link That Bridges Age to Atherosclerosis (The VALIDATE Study) Start of enrollment: 2004 Jun 22
- REVEAL: Reduction of Infarct Expansion and Ventricular Remodeling With Erythropoietin After Large Myocardial Infarction Start of enrollment: 2005 Sep 01
Publications & Presentations
PubMed
- Structure-Function Relationship of the Ryanodine Receptor Cluster Network in Sinoatrial Node Cells.Alexander V Maltsev, Valeria Ventura Subirachs, Oliver Monfredi, Magdalena Juhaszova, Pooja Ajay Warrier
Cells. 2024-11-14 - Lifelong longitudinal assessment of the contribution of multi-fractal fluctuations to heart rate and heart rate variability in aging mice: role of the sinoatrial node ...Motahareh Moghtadaei, Syevda Tagirova, Ismayil Ahmet, Jack Moen, Edward G Lakatta
Geroscience. 2024-10-01 - RelA-mediated signaling connects adaptation to chronic cardiomyocyte stress with myocardial and systemic inflammation in the ADCY8 model of accelerated aging.Vikas Kumar, Kevin Christian Bermea, Dhaneshwar Kumar, Amit Singh, Anjali Verma
Geroscience. 2024-10-01
Journal Articles
- The Dilemma of Coronavirus Disease 2019, Aging, and Cardiovascular DiseaseMajd Alghatrif, Oscar Cingolani, Edward G Lakatta, JAMA Cardiology
Authored Content
- The Dilemma of Coronavirus Disease 2019, Aging, and Cardiovascular DiseaseMay 2020
- The Dilemma of Coronavirus Disease 2019, Aging, and Cardiovascular DiseaseApril 2020
- The Dilemma of Coronavirus Disease 2019, Aging, and Cardiovascular DiseaseApril 2020
Grant Support
- Mitochondrial-Sr CA2+ Cycling Interaction In Cardiac Pacemaker CellsNational Institute On Aging2011
- Beat To Beat Ca2+-Dependent Regulation Of Pacemaker Cell Rate And RhythmNational Institute On Aging2011
- Adenylyl Cyclase And Phosphodiesterase In Lipid Rafts Of Pacemaker CellsNational Institute On Aging2011
- The Reveal StudyNational Institute On Aging2010–2011
- Protein Phosphatase1 Regulates Normal Automaticity Of Heart Pacemaker Node CellsNational Institute On Aging2010–2011
- Biochemistry And Signaling Of Receptor For Advanced Glycation END ProductsNational Institute On Aging2010–2011
- Are Sanc From The Center Or Periperal Area Of The Sinoatrial Node Different?National Institute On Aging2010–2011
- Soluble Receptor For Advanced Glycation END Products For Therapeutic ApplicationNational Institute On Aging2009–2011
- Phosphodiesterases Restrict Spontaneous Beating Of Cardiac Pacemaker CellsNational Institute On Aging2009–2011
- Phosphodiesterases 3 And 4 Regulate Local CA2+ Releases And Beating Of PacemakerNational Institute On Aging2009–2011
- Matching ATP Supply And Demand In Cardiac Pacemaker CellsNational Institute On Aging2009–2011
- Genome-Wide Association Study Of Cardiovascular Traits In 6142 SardiniansNational Institute On Aging2009–2011
- Effects Of Aging On Experimental Atherosclerosis In Nonhuman PrimatesNational Institute On Aging2009–2011
- Effects Of Age And Conditioning Status On REST And Exercise Cardiac PerformanceNational Institute On Aging2009–2011
- Effect On Metalloprotease Inhibition On Age-Associated Arterial RemodelingNational Institute On Aging2009–2011
- Decreased Pacemaker Activity In Aged Sinoatrial NodeNational Institute On Aging2009–2011
- Cultured Adult Rabbit Pacemaker Cells For Gene Transfer StudiesNational Institute On Aging2009–2011
- Calpain-1 Activity And Central Arterial AgingNational Institute On Aging2009–2011
- Both PKA And Camkii Phosphorylation Drive Pacemaker Cell AutomaticityNational Institute On Aging2009–2011
- Age-Associated Changes In Arterial Proteome And Aortic Smooth Muscle SignalingNational Institute On Aging2009–2011
- Age Associated Changes In Structural And Functional Cardio-Vascular PropertiesNational Institute On Aging2009–2011
- A PUFA Dietary Intervention For Heart RateNational Institute On Aging2009–2011
- Suppression Of Beta-Arrestin1 Phosphorylation And Function By Beta-Arrestin2National Institute On Aging2010
- RGS2 Constitutes A Negative Regulator Of Beta2-Adrenergic GI SignalingNational Institute On Aging2010
- Agonist Stereochemistry Determines Beta2-Adrenergic G Protein CouplingNational Institute On Aging2010
- Dilated Cardiomyopathy With Increased SR CA2+ Loading In The Alpha 1ctg MouseNational Institute On Aging2009–2010
- Cholinergic Regulation Of Pka-Dependent CA2+ Cycling In Pacemaker CellsNational Institute On Aging2009–2010
- Ca2+-Stimulated Basal Adenylyl Cyclase Activity Localization In Membrane LipidNational Institute On Aging2009–2010
- Phosphodiesterases Restrict Spontaneous Beating Of Cardiac Pacemaker CellsNational Institute On Aging2008
- Phosphodiesterases 3 And 4 Regulate Local CA2+ Releases And Beating Of PacemakerNational Institute On Aging2008
- Effects Of Aging On Experimental Atherosclerosis In Nonhuman PrimatesNational Institute On Aging2008
- Effect On Metalloprotease Inhibition On Age-Associated Arterial RemodelingNational Institute On Aging2008
- Dilated Cardiomyopathy With Increased SR CA2+ Loading In The Alpha 1ctg MouseNational Institute On Aging2008
- Defining Unique Cardiac Proteome: Comparing Sino-Atrial Node, Atria, VentricleNational Institute On Aging2008
- Cholinergic Regulation Of Pka-Dependent CA2+ Cycling In Pacemaker CellsNational Institute On Aging2008
- Calpain-1 Activity And Central Arterial AgingNational Institute On Aging2008
- Both PKA And Camkii Phosphorylation Drive Pacemaker Cell AutomaticityNational Institute On Aging2008
- Age-Associated Changes In Arterial Proteome And Aortic Smooth Muscle SignalingNational Institute On Aging2008
- Age Associated Changes In Structural And Functional Cardio-Vascular PropertiesNational Institute On Aging2007–2008
- Progress In The Intracellular Clock That Drives The Heart'S PacemakerNational Institute On Aging2007
- Central Arterial Aging: Humans To MoleculesNational Institute On Aging2006–2007
- Progress In The Intracellular Clock That Drives The HearNational Institute On Aging2006
- Age Associated Changes In Vascular Stiffness PropertiesNational Institute On Aging1992–2002
- Activation Of Distinct Camp- And Cgmp-Dependent Pathways By NO In CardiomyocytesNational Institute On Aging1998–2000
- Ion Transport MechanismsNational Institute On Aging1999
- Mechanism For Signal Transduction Of Opioid Receptor Stimulation Of MyocytesNational Institute On Aging1992–1993
- Age Associated Changes In Vascular PropertiesNational Institute On Aging1991
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