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Office
5600 Nathan Shock Dr
Baltimore, MD 21224Phone+1 410-558-8202Fax+1 410-558-8150
Education & Training
- Johns Hopkins UniversityResidency, Internal Medicine, 1975 - 1976
- MedStar Health/Georgetown-Washington Hospital CenterFellowship, Cardiovascular Disease, 1974 - 1975
- University of RochesterResidency, Internal Medicine, 1970 - 1972
- Georgetown University School of MedicineClass of 1970
Certifications & Licensure
- MD State Medical License 1973 - 2026
- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Cardiovascular Disease
Awards, Honors, & Recognition
- Elected Member The American Society for Clinical Investigation, 1984
Clinical Trials
- Vascular Aging: The Link That Bridges Age to Atherosclerosis (The VALIDATE Study) Start of enrollment: 2004 Jun 22
- REVEAL: Reduction of Infarct Expansion and Ventricular Remodeling With Erythropoietin After Large Myocardial Infarction Start of enrollment: 2005 Sep 01
Publications & Presentations
PubMed
- Ca/Calmodulin-Dependent Protein Kinase II (CaMKII) Regulates Basal Cardiac Pacemaker Function: Pros and Cons.Tatiana M Vinogradova, Edward G Lakatta
Cells. 2024-12-25 - Basic Science and Pathogenesis.Carla Rocha Dos Santos, Mackenzie J Barnett, Ross A McDevitt, Wen Wei, Valentina I Zernetkina
Alzheimer's & Dementia. 2024-12-01 - Basic Science and Pathogenesis.Mackenzie J Barnett, Mahdi Haghkar, Carla Rocha Dos Santos, Ross A McDevitt, Valentina I Zernetkina
Alzheimer's & Dementia. 2024-12-01
Journal Articles
- The Dilemma of Coronavirus Disease 2019, Aging, and Cardiovascular DiseaseMajd Alghatrif, Oscar Cingolani, Edward G Lakatta, JAMA Cardiology
Authored Content
- The Dilemma of Coronavirus Disease 2019, Aging, and Cardiovascular DiseaseMay 2020
- The Dilemma of Coronavirus Disease 2019, Aging, and Cardiovascular DiseaseApril 2020
- The Dilemma of Coronavirus Disease 2019, Aging, and Cardiovascular DiseaseApril 2020
Grant Support
- Mitochondrial-Sr CA2+ Cycling Interaction In Cardiac Pacemaker CellsNational Institute On Aging2011
- Beat To Beat Ca2+-Dependent Regulation Of Pacemaker Cell Rate And RhythmNational Institute On Aging2011
- Adenylyl Cyclase And Phosphodiesterase In Lipid Rafts Of Pacemaker CellsNational Institute On Aging2011
- The Reveal StudyNational Institute On Aging2010–2011
- Protein Phosphatase1 Regulates Normal Automaticity Of Heart Pacemaker Node CellsNational Institute On Aging2010–2011
- Biochemistry And Signaling Of Receptor For Advanced Glycation END ProductsNational Institute On Aging2010–2011
- Are Sanc From The Center Or Periperal Area Of The Sinoatrial Node Different?National Institute On Aging2010–2011
- Soluble Receptor For Advanced Glycation END Products For Therapeutic ApplicationNational Institute On Aging2009–2011
- Phosphodiesterases Restrict Spontaneous Beating Of Cardiac Pacemaker CellsNational Institute On Aging2009–2011
- Phosphodiesterases 3 And 4 Regulate Local CA2+ Releases And Beating Of PacemakerNational Institute On Aging2009–2011
- Matching ATP Supply And Demand In Cardiac Pacemaker CellsNational Institute On Aging2009–2011
- Genome-Wide Association Study Of Cardiovascular Traits In 6142 SardiniansNational Institute On Aging2009–2011
- Effects Of Aging On Experimental Atherosclerosis In Nonhuman PrimatesNational Institute On Aging2009–2011
- Effects Of Age And Conditioning Status On REST And Exercise Cardiac PerformanceNational Institute On Aging2009–2011
- Effect On Metalloprotease Inhibition On Age-Associated Arterial RemodelingNational Institute On Aging2009–2011
- Decreased Pacemaker Activity In Aged Sinoatrial NodeNational Institute On Aging2009–2011
- Cultured Adult Rabbit Pacemaker Cells For Gene Transfer StudiesNational Institute On Aging2009–2011
- Calpain-1 Activity And Central Arterial AgingNational Institute On Aging2009–2011
- Both PKA And Camkii Phosphorylation Drive Pacemaker Cell AutomaticityNational Institute On Aging2009–2011
- Age-Associated Changes In Arterial Proteome And Aortic Smooth Muscle SignalingNational Institute On Aging2009–2011
- Age Associated Changes In Structural And Functional Cardio-Vascular PropertiesNational Institute On Aging2009–2011
- A PUFA Dietary Intervention For Heart RateNational Institute On Aging2009–2011
- Suppression Of Beta-Arrestin1 Phosphorylation And Function By Beta-Arrestin2National Institute On Aging2010
- RGS2 Constitutes A Negative Regulator Of Beta2-Adrenergic GI SignalingNational Institute On Aging2010
- Agonist Stereochemistry Determines Beta2-Adrenergic G Protein CouplingNational Institute On Aging2010
- Dilated Cardiomyopathy With Increased SR CA2+ Loading In The Alpha 1ctg MouseNational Institute On Aging2009–2010
- Cholinergic Regulation Of Pka-Dependent CA2+ Cycling In Pacemaker CellsNational Institute On Aging2009–2010
- Ca2+-Stimulated Basal Adenylyl Cyclase Activity Localization In Membrane LipidNational Institute On Aging2009–2010
- Phosphodiesterases Restrict Spontaneous Beating Of Cardiac Pacemaker CellsNational Institute On Aging2008
- Phosphodiesterases 3 And 4 Regulate Local CA2+ Releases And Beating Of PacemakerNational Institute On Aging2008
- Effects Of Aging On Experimental Atherosclerosis In Nonhuman PrimatesNational Institute On Aging2008
- Effect On Metalloprotease Inhibition On Age-Associated Arterial RemodelingNational Institute On Aging2008
- Dilated Cardiomyopathy With Increased SR CA2+ Loading In The Alpha 1ctg MouseNational Institute On Aging2008
- Defining Unique Cardiac Proteome: Comparing Sino-Atrial Node, Atria, VentricleNational Institute On Aging2008
- Cholinergic Regulation Of Pka-Dependent CA2+ Cycling In Pacemaker CellsNational Institute On Aging2008
- Calpain-1 Activity And Central Arterial AgingNational Institute On Aging2008
- Both PKA And Camkii Phosphorylation Drive Pacemaker Cell AutomaticityNational Institute On Aging2008
- Age-Associated Changes In Arterial Proteome And Aortic Smooth Muscle SignalingNational Institute On Aging2008
- Age Associated Changes In Structural And Functional Cardio-Vascular PropertiesNational Institute On Aging2007–2008
- Progress In The Intracellular Clock That Drives The Heart'S PacemakerNational Institute On Aging2007
- Central Arterial Aging: Humans To MoleculesNational Institute On Aging2006–2007
- Progress In The Intracellular Clock That Drives The HearNational Institute On Aging2006
- Age Associated Changes In Vascular Stiffness PropertiesNational Institute On Aging1992–2002
- Activation Of Distinct Camp- And Cgmp-Dependent Pathways By NO In CardiomyocytesNational Institute On Aging1998–2000
- Ion Transport MechanismsNational Institute On Aging1999
- Mechanism For Signal Transduction Of Opioid Receptor Stimulation Of MyocytesNational Institute On Aging1992–1993
- Age Associated Changes In Vascular PropertiesNational Institute On Aging1991
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