EdwardHowardKaplanMD

Oncology • Morton Grove, IL

Breast Cancer, Cancer Genetics/Cancer Risk Assessment, Gastrointestinal Cancer, Hematologic Oncology

City of Hope- Chicago Medical Oncology; Director of GI oncology

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Office
9300 Waukegan Road
Morton Grove, IL 60053
Phone+1 847-675-3900

Fax+1 847-675-3930

Summary

Dr. Kaplan practices at Hematology / Oncology of the North Shore, which has recently joined City of Hope, a leader in cancer research and treatment

Education & Training

McGaw Medical Center of Northwestern UniversityFellowship, Hematology and Medical Oncology, 1988
McGaw Medical Center of Northwestern UniversityResidency, Internal Medicine, 1982 - 1985
Loyola University Chicago Stritch School of MedicineClass of 1982
University of Illinois College of Medicine at UrbanaB.S., Biology, 1978

Certifications & Licensure

IL State Medical License 1983 - 2026
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

Teaching and Service Award, finalist Rush-Presbyterian-St. Luke’s Med. Ctr, 1991
Bill Veek Fellow Northwestern University Medical School, 1987
Galter Fellow Northwestern University Medical School, 1986
Phi Eta Sigma University of Illinois, 1974
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Clinical Trials

Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer Start of enrollment: 1998 Oct 01
Completed
Phase 3
Combination Chemotherapy in Treating Patients With Stage III Colon Cancer Start of enrollment: 1999 May 01
Completed
Phase 3
Study of Tamoxifen and Raloxifene (STAR) for the Prevention of Breast Cancer in Postmenopausal Women Start of enrollment: 1999 May 01
Completed
Phase 3
Topotecan Hydrochloride in Treating Children With Meningeal Cancer That Has Not Responded to Previous Treatment Start of enrollment: 2000 Apr 01
Completed
Phase 2
S0008: Chemotherapy Plus Biological Therapy in Treating Patients With Melanoma Start of enrollment: 2000 Aug 01
Completed
Phase 3
S0016 Combination Chemotherapy With Monoclonal Antibody Therapy in Newly Diagnosed Non-Hodgkin's Lymphoma
ACTIVE_NOT_RECRUITING
PHASE3
Combination Chemotherapy in Treating Children With Refractory or Relapsed Hodgkin's Lymphoma Start of enrollment: 2001 May 01
Completed
Phase 2
Combination Chemotherapy in Treating Patients With Stage III or Stage IV Ovarian Epithelial Cancer or Primary Peritoneal Cancer Start of enrollment: 2001 Jan 01
Completed
Phase 3
Carboxypeptidase-G2 in Treating Nervous System Toxic Effects in Patients Given an Overdose of Intrathecal Methotrexate Start of enrollment: 1993 Nov 01
Completed
Not Applicable
Comparison of Chemotherapy Regimens in Treating Children With Relapsed or Progressive Rhabdomyosarcoma Start of enrollment: 2001 Nov 01
Completed
Phase 2
Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for Ependymoma Start of enrollment: 2003 Aug 01
Completed
Phase 2
Arsenic Trioxide in Treating Men With Germ Cell Cancer Start of enrollment: 2002 Apr 01
Completed
Phase 2
Combination Chemotherapy and Bevacizumab in Treating Patients With Locally Advanced, Metastatic, or Recurrent Colorectal Cancer Start of enrollment: 2004 Apr 01
Terminated
Phase 3
Dexamethasone Compared With Prednisone During Induction Therapy and Methotrexate With or Without Leucovorin During Maintenance Therapy in Treating Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia Start of enrollment: 2003 Dec 29
Completed
Phase 3
Gemcitabine, Carboplatin, and Bortezomib in Advanced or Recurrent Non-Small Cell Lung Cancer Start of enrollment: 2004 Jan 01
Completed
Phase 2
Carboplatin, Vincristine, and Temozolomide in Treating Children With Progressive and/or Symptomatic Low-Grade Glioma Start of enrollment: 2004 Jul 01
Completed
Not Applicable
Genetic Analysis in Identifying Late-Occurring Complications in Childhood Cancer Survivors Start of enrollment: 2004 Mar 25
ACTIVE_NOT_RECRUITING
Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma Start of enrollment: 2004 Apr 30
COMPLETED
PHASE3
Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas Start of enrollment: 2005 Mar 21
Completed
Phase 2
Radiation Therapy in Treating Young Patients With Gliomas Start of enrollment: 2006 Nov 01
Completed
Phase 2
Ixabepilone in Treating Young Patients With Refractory Solid Tumors Start of enrollment: 2006 Apr 01
Completed
Phase 2
Combination Chemotherapy, Radiation Therapy, and/or Surgery in Treating Patients With High-Risk Kidney Tumors Start of enrollment: 2006 Jun 01
Completed
Phase 2
Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma Start of enrollment: 2007 Feb 05
Completed
Phase 3
Vincristine, Dactinomycin, and Doxorubicin With or Without Radiation Therapy or Observation Only in Treating Younger Patients Who Are Undergoing Surgery for Newly Diagnosed Stage I, Stage II, or Stage III Wilms' Tumor Start of enrollment: 2006 Nov 06
Active, not recruiting
Phase 3
Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma Start of enrollment: 2006 Dec 26
Completed
Phase 3
Bevacizumab, Sorafenib Tosylate, and Temsirolimus in Treating Patients With Metastatic Kidney Cancer Start of enrollment: 2007 Sep 14
Completed
Phase 2
Combination Chemotherapy With or Without Radiation Therapy in Treating Young Patients With Newly Diagnosed Stage III or Stage IV Wilms' Tumor Start of enrollment: 2007 Feb 26
Active, not recruiting
Phase 3
Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma/PNET Start of enrollment: 2007 May 23
ACTIVE_NOT_RECRUITING
PHASE3
TroVax Renal Immunotherapy Survival Trial Start of enrollment: 2006 Sep 01
Completed
Phase 3
Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma Start of enrollment: 2007 Jan 22
ACTIVE_NOT_RECRUITING
PHASE3
Risk-Group Classification of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Start of enrollment: 2003 Dec 01
Completed
BETH Study: Treatment of HER2 Positive Breast Cancer With Chemotherapy Plus Trastuzumab vs Chemotherapy Plus Trastuzumab Plus Bevacizumab Start of enrollment: 2008 Apr 01
Terminated
Phase 3
Study of Macitentan (ACT-064992) on Morbidity and Mortality in Patients With Symptomatic Pulmonary Arterial Hypertension Start of enrollment: 2008 May 01
Completed
Phase 3
Clinical Study to Assess the Long-term Safety and Tolerability of ACT 064992 in Patients With Symptomatic Pulmonary Arterial Hypertension Start of enrollment: 2008 Oct 17
Completed
Phase 3
Rheumatological Evaluation of Anastrozole and Letrozole as Adjuvant Treatment in Post-menopausal Women With Breast Cancer Start of enrollment: 2008 Mar 01
Completed
Phase 4
Safety and Exploratory Efficacy of Kanglaite Injection in Pancreatic Cancer Start of enrollment: 2008 Aug 01
Completed
Phase 2
A Study to Evaluate the Efficacy and Safety of Lenalidomide as Maintenance Therapy for Patients With B-Cell Chronic Lymphocytic Leukemia (CLL) Following Second Line Therapy Start of enrollment: 2009 Jan 27
Completed
Phase 3
Collecting and Storing Samples of Bone Marrow and Blood From Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma Start of enrollment: 2006 Sep 25
Completed
Study of Kidney Tumors in Younger Patients Start of enrollment: 2006 Feb 27
ACTIVE_NOT_RECRUITING
Collecting and Storing Biological Samples From Young Patients With Hodgkin?s Lymphoma Start of enrollment: 2006 Oct 23
Completed
Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma Start of enrollment: 2000 Nov 06
Recruiting
Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma Start of enrollment: 1999 Mar 15
Completed
Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors Start of enrollment: 2004 Feb 16
Completed
Safety Study of Cetuximab in Combination With Cisplatin and Vinorelbine to Treat Advanced Non-small Cell Lung Cancer Start of enrollment: 2010 Jul 01
Completed
Phase 2
Randomized Study of ON 01910.Na in Refractory Myelodysplastic Syndrome Patients With Excess Blasts Start of enrollment: 2010 Nov 01
Completed
Phase 3
A Study of ChemoFx® Chemoresponse Assay in Solid Tumors - ChemoFx® Registry Study Start of enrollment: 2010 Nov 01
Terminated
NBRST: Prospective Neo-adjuvant REGISTRY Trial Start of enrollment: 2011 Jul 01
Completed
Study of Glembatumumab Vedotin (CDX-011) in Patients With Metastatic, gpNMB Over-Expressing, Triple Negative Breast Cancer Start of enrollment: 2013 Nov 01
Completed
Phase 2
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Publications & Presentations

PubMed

34 citations
A Randomized, Open-Label, Safety and Exploratory Efficacy Study of Kanglaite Injection (KLTi) plus Gemcitabine versus Gemcitabine in Patients with Advanced Pancreatic ...
Lee S. Schwartzberg, Francis P. Arena, Bryan J. Bienvenu, Edward H. Kaplan, Luis H. Camacho
Journal of Cancer. 2017-07-03
13 citations
Importance and relevance of pulmonary symptoms among patients receiving second- and third-line treatment for advanced non-small-cell lung cancer: support for the conte...
Susan Magasi, Rajiv Mallick, Karen Kaiser, Jyoti D. Patel, Thomas E. Lad
Clinical Lung Cancer. 2013-05-01
1416 citations
Measuring fatigue and other anemia-related symptoms with the Functional Assessment of Cancer Therapy (FACT) measurement system
Suzanne B. Yellen, David Cella, Kimberly Webster, Carol Blendowski, Edward Kaplan
Journal of Pain and Symptom Management. 1997-02-01

Journal Articles

Magasi S, Mallick R, Menendez B, Patel J, Johnson ML, Kaplan E, Cella D, J Supp Onc, 1/1/2013
Magasi S, Mallick R, Kaiser K, Patel J, Lad T, Johnson M, Kaplan EH, Cella D, Clin Lung Cancer, 1/1/2013
Butts CA, Bodkin D, Middleman EL, Englund CW, Ellison D, Alam Y, Kreisman H, Graze P, Maher J, Ross HJ, Ellis PM, McNulty W, Kaplan E, Pautret V, Weber MR, and Shephe..., Journal of Clinical Oncology, 1/20/2007
Seifert SA, Dart RC and Kaplan EH, J Toxicol Clin Toxicol, 1/1/1998
Yellen SB, Cella DF, Webster K, Blendowski C, Kaplan EH, and Sarokhan B, Journal of Pain and Symptom Management, 1/1/1997
Martenson JA, Lipsitz S, Wagner H, Kaplan EH, Otteman LA, Schuchter LM, Mansour EG, Talamonti MS, and Benson AB III, Int J Radiat Oncol Biol Phys, 1/1/1996
Cella DF, Bonomi AE, Lloyd SR, Tulsky DS, Kaplan EH, and Bonomi P, Lung Cancer, 1/1/1995
Taylor MA, Reddy S, Lee MS, Bonomi P, Taylor SG, Kaplan EH, Faber LP, Warren W, and Hendrickson FR, Cancer, 1/1/1994
Kaplan EH and Leslie WT, Current Opinion in Oncology, 1/1/1993
Kahn D, Weiner GJ, Huston M, Dowlatshahi K, Feole J, Kaplan EH, Grossman SJ, Joyce JM, and Acierno JB, Antibody, Immunoconjugates, and Radiopharmaceuticals, 1/1/1993
Cella DF, Tulsky DS, Gray G, Sarafian B, Lloyd S, Linn E, Bonomi A, Silberman M, Yellen SB, Wincour P, Brannon J, Eckberg K, Purl S, Blendowski C, Goodman M, Barnicle ..., Journal of Clinical Oncology, 1/1/1993
Collier BD, Abdel-Nabi H, Doerr RV, Harwood SJ, Olsen J, Kaplan EH, Winzelberg GG, Grossman SJ, Krag DN, Mitchell EP, Radiology, 1/1/1992
Reddy S, Lee MS, Bomoni P, Taylor SG IV, Kaplan EH, Gale M, Faber LP, Warren W, Kittle CF, and Hendrickson FR, Int J Radiation Oncology Biol Phys, 1/1/1992
Kaplan EH, Rosen ST, Norris DB, Roenigk HH, Saks SR, Bunn PA, Journal of the National Cancer Institute, 1/1/1990
Zimmer AM, Kazikiewicz JM, Kaplan EH, Lurain J, Miller DS, Webber DI, Goldman-Leiken R, Manzel L, Gilyon K, Radosevich JA, Spies WG, Spies SM, Rosen ST, J Nuclear Med, 1/1/1989
Rosen St, Zimmer AM, Goldman-Leikin R, Kazikiewicz, Dykewicz MS, and Kaplan EH, International Journal of Nuclear Medicine and Biology, 1/1/1989
Zimmer AM, Kazikiewicz JM, Canade AB, Goldman-Leikin RJ, Kaplan EH, Spies SM, Rosen ST, Antibody Immunoconjugates and Radiopharmaceuticals, 1/1/1989
Zimmer AM, Kaplan EH, Kazikiewicz JM, Goldman-Leikin R, Gilyon KA, Dykewicz MS, Spies WG, Silverstein EA, Spies SM, Rosen ST, Antibody Immunoconjugates and Radiopharmaceuticals, 1/1/1988
Spies WG, Zimmer AM, Robinson PG, LoCicero J, Radosevich JA, Kaplan EH, Canade AB, Manzel L, Spies SM, Maguire RT, Rosen ST, Radiology, 1/1/1988
Goldman-Leikin RE, Kaplan EH, Zimmer AM, Kazikiewicz J, Rosen ST, Experimental Hematology, 1/1/1988
Rosen ST, Kaplan EH, Zimmer AM, Immunopathology and Immunotherapy Letter, 1/1/1988
Zimmer AM, Rosen ST, Spies SM, Goldman-Leikin R, Kazikiewicz JM, Kaplan EH, Journal of Nuclear Medicine, 1/1/1988
Rosen ST, Zimmer AM, Goldman-Leikin R, Gordon L1, Kazikiewicz JM, Kaplan EH, Variakojis D, Marder RJ, Dykewicz MS, Piergies, Journal of Clinical Oncology, 1/1/1987
Citrin DL, Wallermark C, Nadler R, Geiger C, Tuttle K, Kaplan EH, Hauk W, Cancer, 1/1/1986
Citrin DL, Kies MS, Wallermark C, Khandekar J, Kaplan EH, Comacho F, Lind R, Cancer, 1/1/1985
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Books/Book Chapters

Chapter: Oncology: D, Systemic Therapy
Page 261 - 267Kaplan, Edward and Velasco, Jose MEditors: Bines, S. et al.Saunders/ Elsevier, Inc.Edition 4th,2006
Chapter: Monoclonal antibodies in the treatment of lymphoreticular and solid tumors
Page 579 - 583Kaplan EH, Duda RB, Zimmer AM, Rosen STEditors: Economou SG, et al..Lea & Febiger1991
Chapter: Neoadjuvant preoperative chemotherapy and concurrent split-course radiotherapy in stage III non-small cell lung cancer: Improved response rate when Etoposide is added to Cisplatin and infusional 5-flu
Page 138 - 144Kaplan EH, Bonomi PD, Gale M, Taylor IV SG, Reddy S, Lee MS, Purl S, Faber LPEditors: Salmon SE.W.B. Saunders Co.1990
Chapter: Current status of monoclonal antibodies in cancer therapy
Page 86 - 109Kaplan EH, Goldman-Leikin RE, Radosevich JA, Rosen STSpringer Publishing Co.1989
Chapter: The diagnostic and therapeutic use of monoclonal antibodies in colorectal cancer-current status
Page 125 - 134Kaplan EHEditors: Harris SE and Levin B.1989
Chapter: Oncology, Systemic Therapy
Kaplan EHEditors: Economou SG, Deziel DJ, Witt TR, et al.WB Saunders Co.Edition 2nd,1988
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Abstracts/Posters

Tagliaferri MA, Schwartzberg LS, Chen MM, Camacho LH, Kaplan EH, Arena FP, Bienvenu BJ, North SE, Li D, and Patel H, ASCO.org and JCO.org, 1/1/2013
Blackwell KL, Kaplan EH, Franco SX, Marcom PK, Maleski JE, Sorensen MJ, and Berger MS, Proc Amer Soc Clin Oncol, 1/1/2004
Kaplan EH, Jones CM, and Berger MS, Proc Amer Soc Clin Oncol, 1/1/2003
Kaplan E, Kleinman M, Patel A, Kozloff M, Tangonan C, and Cowan M, Proc Amer Soc Clin Oncol, 1/1/2001
O’Brien TM, Anupama R, Venugopal P, Kaplan EH, Gupta-Burt S, Foster GS and Gregory SA, Blood, 1/1/1999
Kaplan EH, Kleinman MB, Rhoades D. Wechsler J and Yale K, Journal of Pain and Symptom Management, 1/1/1999
Kleinman MB, Kaplan EH, Rhoades DR, Zats S and Wechsler JB, Blood, 1/1/1999
Soff G. Hong J, Fishman D, Kleinman MB, Kaplan EH, Zagzag D, Shultz R, Cundiff D, Park S, Enghild J, Sharon-Stack M and Gately S. Angiostatin, Blood, 1/1/1998
Lindemann K and Kaplan EH, Oncology Nursing Forum, 1/1/1998
Lindemann K, Brodell C and Kaplan EH, ONS Congress, San Francisco, CA, 1/1/1998
Lindemann K and Kaplan EH, ONS, 1/1/1997
Kaplan EH, Gerish R, Lindemann K and Eisenstein M, Proc Amer Soc Clin Oncol, Denver, CO, 1/1/1997
Yellen S, Cella D and Kaplan EH, Proc Amer Soc Clin Oncol, 1/1/1995
Cella DF, Bonomi AE, Lloyd S, Tulksy D, Bonomi P, Kaplan EH, 7th World Conference on Lung Cancer, Colorado Springs, CO, 1/1/1994
Bonomi P, Gayle M, Faber LP, Reddy S, Kaplan EH, Lincoln S, Purl S, Proc Amer Soc Clin Oncol, Orlando, FL, 1/1/1993
Cobleigh MA, Tracy DM, Kleinman MD, Walsh NM, and Kaplan EH, Proc Amer Soc Clin Onc., Orlando, FL, 1/1/1993
Cobleigh MA and Kaplan EH, 15th Annual San Antonio Breast Cancer Symposium, San Antonio, TX, 1/1/1992
Bonomi P, Gale M, Faber LP, Reddy SG, Kaplan EH, Purl S, Taylor SG IV, Lee MS, Phillips A, Warren W, Kittle CF, Proc Amer Soc Clin Onc, San Diego, CA, 1/1/1992
Bonomi P, Gale M, Taylor SG, Kaplan EH, Purl S, Reddy S, Lee MS, Phillips A, Kittle CF, Warren W, Faber LP, Proc Amer Soc Clin Onc, Washington, DC, 1/1/1990
Thomas C, Bonomi P, Gale M, Taylor SG, Kaplan EH, Rowland K, Reddy S, Lee MS, Phillips A, Kittle CF, Warren W, Faber LP, Proc Amer Soc Clin Onc, Washington, DC, 1/1/1990
Kaplan EH, Bonomi P, Gale M, Taylor SG, Reddy S, Lee MS, Purl S, Faber LP, International Conference on the Adjuvant Therapy of Cancer, 1/1/1990
Kaplan EH, Hardmann DD, Fordham EW, Rayudu GVS, Proc Amer Soc Clin Oncol, Washington, DC, 1/1/1990
Thomas C, Purl S, Bonomi PD, Murthy A, Kaplan EH, 12th Annual San Antonio Breast Cancer Symposium, 1/1/1989
Kaplan EH, Bonomi P, Faber LP, Reddy S, Phillips A, Lee MS, Purl S, Taylor SG IV, Proc Am Soc Clin Oncol, San Francisco, CA, 1/1/1989
Kaplan EH, Kazikiewicz JM, Zimmer AM, Goldman-Leikin RE, Rosen ST, Fourth International Conference on Monoclonal Antibody Immunoconjugates for Cancer, San Diego, CA, 1/1/1989
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