EduardoMarbanMDPhD
Cardiology • Los Angeles, CAExecutive Director, Smidt Heart Institute, Cedars-Sinai, Los Angeles CA
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Office
8700 Beverly Blvd
Suite 1090
Los Angeles, CA 90048Phone+1 310-423-7557Fax+1 310-423-3522
Summary
- My current research areas are using biologically based therapies for cardiac regeneration and biological pacemakers. The research using cardiosphere-derived cells has demonstrated that the cells are better in their functional repair capacity and in their angiogenic ability to secrete favorable paracrine factors that other cells in clinical use do not. The lab is studying various methods of delivering the cells and determining the immunogenicity of allogeneic stem cells in small and large animal models.
Education & Training
Johns Hopkins UniversityFellowship, Cardiovascular Disease, 1984 - 1985- Johns Hopkins UniversityResidency, Internal Medicine, 1981 - 1984
Yale-New Haven HospitalPost-Doctoral Fellowship, 1980 - 1981
Yale UniversityPh.D., Physiology, 1981
Yale School of MedicineClass of 1980- Wilkes CollegeB.S., Mathematics , Summa Cum Laude, 1970 - 1974
Certifications & Licensure
CA State Medical License 2007 - 2025
MD State Medical License 1983 - 2013- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Cardiovascular Disease
Awards, Honors, & Recognition
- Cedars-Sinai Medical Center Pioneer in Medicine Award 2017
- Johns Hopkins Society of Scholars 2017
- Distinguished Scientist Award American College of Cardiology, 2014
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Publications & Presentations
PubMed
- 119 citationsFibroblasts Rendered Antifibrotic, Antiapoptotic, and Angiogenic by Priming With Cardiosphere-Derived Extracellular Membrane Vesicles.Eleni Tseliou, Joseph Fouad, Heidi Reich, Leandro Slipczuk, Geoffrey de Couto
Journal of the American College of Cardiology. 2015-08-11 - 633 citationsExosomes as critical agents of cardiac regeneration triggered by cell therapy.Ahmed Ibrahim, Ke Cheng, Eduardo Marbán
Stem Cell Reports. 2014-05-06 - 503 citationsRelative Roles of Direct Regeneration Versus Paracrine Effects of Human Cardiosphere-Derived Cells Transplanted Into Infarcted MiceIsotta Chimenti, Rachel Ruckdeschel Smith, Tao-Sheng Li, Gary Gerstenblith, Elisa Messina
Circulation Research. 2010-03-19
Journal Articles
- Exosomes Secreted by Cardiosphere-Derived Cells Reduce Scarring, Attenuate Adverse Remodelling, and Improve Function in Acute and Chronic Porcine Myocardial InfarctionDaniel Luthringer, Ryan Middleton, Eduardo Marban, European Heart Journal
Press Mentions
Heart Attacks Can Be Silent: Signs to Watch Out ForSeptember 10th, 2022- Heart Attacks Can Be Silent: Signs to Look Out ForSeptember 9th, 2022
- Health News | Researchers Find Cell-Derived Therapy May Help Repair Abnormal Heart RhythmApril 12th, 2022
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Grant Support
- Dedifferentiation Of Cardiomyocytes Into Cardiac Progenitor CellsNational Heart, Lung, And Blood Institute2011–2012
- Electrophysiology And Cell Biology Of Cardiac Stem CellsNational Heart, Lung, And Blood Institute2007–2010
- Isolation &Characterization Of Human Cardiac Stem CellsNational Heart, Lung, And Blood Institute2007–2009
- Cellular Cardiomyoplasty For Acute And Chronic IschemicNational Heart, Lung, And Blood Institute2007–2009
- Structure Of Mitochondrial K+ ChannelsNational Heart, Lung, And Blood Institute2005–2009
- Electrophysiology And Cell Biology Of Cardiac Stem CellsNational Heart, Lung, And Blood Institute2006–2007
- Cellular Cardiomyoplasty For Acute And Chronic IschemicNational Heart, Lung, And Blood Institute2006
- Isolation &Characterization Of Human Cardiac Stem CellsNational Heart, Lung, And Blood Institute2005–2006
- Specialized Center Of Research In Sudden Cardiac DeathNational Heart, Lung, And Blood Institute2000–2004
- Metabolic Control Of Cardiac Ion ChannelsNational Heart, Lung, And Blood Institute1996–2004
- Cellular Mechanisms Of Cardiac Contractile DysfunctionNational Heart, Lung, And Blood Institute1990–2003
- Molecular Dissection Of Cardiac RepolarizationNational Heart, Lung, And Blood Institute2000–2002
- Molecular Pharmacology Of Cardiac Ion ChannelsNational Heart, Lung, And Blood Institute1994–2002
- Molecular Physiology Of Gating And Permeation In Sodium And Calcium ChannelsNational Heart, Lung, And Blood Institute1996–1999
- SCOR In Sudden Cardiac DeathNational Heart, Lung, And Blood Institute1995–1999
- Metabolic Control Of Cardiac Ion ChannelsNational Heart, Lung, And Blood Institute1995–1996
- CA Channel Regulation In Heart CellsNational Heart, Lung, And Blood Institute1986–1993
- Regulation Of CA Channels By CA2+ In Heart CellsNational Heart, Lung, And Blood Institute1988–1990
- CA Channel Regulation By (Ca2+)I In Heart CellsNational Heart, Lung, And Blood Institute1987–1988
- Regulation Of CA Channels By ?Ca2+? In Heart CellsNational Heart, Lung, And Blood Institute1986–1987
Professional Memberships
- Member
- Mark S. Siegel Family FoundationDistinguished Chair
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