Eduardo Nunes Chini MD

PubMed

• Methylglyoxal Reshapes Hepatic and Adipose Tissue Metabolism and Increases Viability of Lymphocytes.
  Naiara Cristina Lucredi, Lucas Paulo J Saavedra, Silvano Piovan, Emanuele P Lima, Mariane Aparecida F Godoy
  Cellular Physiology and Biochemistry. 2025-04-21
• Reevaluating Anti-Inflammatory Therapy: Targeting Senescence to Balance Anti-Cancer Efficacy and Vascular Disease.
  Bernardo Casso-Chapa, Norma Alicia Vazquez González, Nhat-Tu Le, Nicolas L Palaskas, Kevin T Nead
  Arteriosclerosis, Thrombosis, and Vascular Biology. 2025-03-01
• 1 citations
  Liver X Receptors and Inflammatory-Induced C/EBPβ Selectively Cooperate to Control CD38 Transcription.
  Estibaliz Glaría, Pol Rodríguez Martínez, Joan Font-Díaz, Juan Vladimir De la Rosa, Antonio Castrillo
  Journal of Innate Immunity. 2025-01-01

Journal Articles

• HMG-CoA reductase inhibitors decrease hyperglycemia on animal model of Systemic inflammatory response Syndrome (SIRS)  
  Aksoy P, Brown MJ, Chini EN, Journal of Anesthesia and Clinical Research, 1/1/2011
• Cyclic ADP-ribose signaling in sea urchin gametes - metabolism in spermatozoa  
  Chini EN, Thompson MA, Chini CCS, Dousa TP, Am J Physiol Cell Physiol, 1/1/1997
• Different thermostabilities of sarcoplasmic reticulum (Ca2+ + Mg2+)-ATPases from rabbit and trout muscles  
  de Toledo FG, Albuquerque MC, Goulart BH, Chini EN, Comparative Biochemistry & Physiology. Part C Pharmacology, Toxicology, Endocrinology, 1/1/1995

Books/Book Chapters

• Molecular mechanisms of parasite invasion. 
  Chapter: Calcium regulation and signaling in apicomplexan parasites. 
  Page 1 - 12Nagamune K, Moreno SN, Chini EN, Sibley DLEditors: Burleigh B, Soldati D.Landes Bioscience2007
• Cellular signaling and apoptosis research. 
  Chapter: Nuclear calcium signalling: the nuclear envelope store and the regulation of transcription. 
  Page 201 - 219Escande C, Arbildi P, Chini E, Benech JCEditors: Demasi AR.Nova Biomedical Books, New York, NY2007
• Critical care medicine : perioperative management. 
  Chapter: Transfusion medicine for the intensivist. 
  Page 566 - 576Chini EN, Dietz NM, Faust RJEditors: Murray MJ, et al.Lippincott Williams & Wilkins, Philadelphia, PAEdition 2,2002
• Recent Research Developments in Biophysics and Biochemistry 
  Chapter: The new calcium-mobilizing nucleotides cyclic ADP-ribose and NAADP 
  Chini EN, De Toledo FGSResearch Signposts, Trivandrum, India2001
• Methods in Renal Toxicology. 
  Chapter: Microdissection and microanalysis of specific nephron segments from mammalian kidney. 
  Page 97 - 107Chini EN, Dousa TPEditors: Zalups RK, Lash LH.CRC Press, Boca Raton, FL1996
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Abstracts/Posters

• A fatal case of fat embolism
  Schafer JE, Chini EN, MARC Conference, Cincinnati, OH, 1/1/2010
• The role of the CD38/cADPR signaling pathway in oxytocin-induced contraction in human myometrium.
  Zielinska W, Chini E, Vasdev GM, Anesthesiology, 1/1/2007
• Agonist-induced CADPR production in airway smooth muscle (Abstract 767.12)
  Kip SN, Smelter M, Thompson MA, Hunter LW, Iyanoye A, Chini EN, Pabelick CM, Sieck GC, FASEB J, 1/1/2006
• CD38 overexpression influences [Ca2+]i regulation in airway smooth muscle (Abstract 767.11)
  Soares SM, White TA, Bailey JP, Chini EN, Prakash YS, Pabelick CM, Sieck GC, FASEB J, 1/1/2006
• The levels of mRNA encoding plasma membrane calcium pump (pmca) isoforms 2 and 3 in rat kidney cortex is selectively decreased during hypercalciuria.
  Caride AJ, Chini EN, Penniston JT, Dousa TP, J Am Soc Nephrol, 1/1/1998
• Synthesis of cyclic-ADP-ribose, a putative new second messenger, in liver mitochondria.
  Liang M, Chini EN, Dousa TP, Journal of Investigative Medicine, 1/1/1997
• Thyroid hormone increases ADP/ribosyl cyclase activity in rat myocardium.
  Chini EN, De Toledo FGS, Dousa TP, Journal of Investigative Medicine, 1/1/1997
• Administration of beta-estradiol (E2) stimulates generation of cyclic ADP ribose from NAD in rat uterus.
  Chini EN, De Toledo FGS, Dousa TP, Journal of Investigative Medicine, 1/1/1997
• Beta-estradiol (E2) stimulates synthesis of cyclic ADP ribose (CADPR) in rat uterus. (Abstract 1876)
  Chini EN, De Toledo FGS, Dousa TP, FASEB J, 1/1/1997
• Adrenomedullin (ADM) inhibits mesangial cell (MC) proliferation induced by PDGF but not by endothelin (ET-1)
  Chini EN, Chini CSC, Choi E, Burnett JCJ, Grande JP, Dousa TP, J Am Soc Nephrol, 1/1/1996
• Compartmentalization of cAMP signaling in renal mesangial cells (mc) by cAMP phosphodiesterase (PDE) isozymes pde4 and pde3. (Abstract 57)
  Grande JP, Chini CSC, Chini EN, Dousa TP, Mol Biol Cell, 1/1/1996
• Diversity of plasma membrane calcium pump isoforms (RPMCAs) along the rat nephron. (Abstract M-POS264)
  Caride A, Chini E, Homma S, Penniston J, Dousa T, Biophys J, 1/1/1996
• Formation of reactive oxygen metabolites in rat mesangial cells (mc) is selectively suppressed by rolipram, inhibitor of cAMP phosphodiesterase isozyme IV (PDE-IV. (Ab...
  Chini CS, Grande JP, Chini EN, Dousa TP, FASEB J, 1/1/1996
• Enzymatic synthesis of naadp by ADP-ribosyl cyclases. (Abstract 822).
  Chini EN, Thompson M, Dousa TP, FASEB J, 1/1/1996
• Compartmentalization of cAMP-protein kinase a (pKA) signaling by isozymes PDE-IV and PDE-III in rat mesangial cells.
  Dousa TP, Chini CSC, Chini EN, Tsuboi Y, Grande JP, Biochem Soc Trans, 1/1/1996
• Plasma membrane CA pump (RPMCA) mRNAs encoding isoforms 1B and 2B in segments of rat cortical tubules and their change in decreased CA reabsorption.
  Caride AJ, Chini EN, Penniston JT, Dousa TP, J Am Soc Nephrol, 1/1/1996
• Isozymes of cAMP phosphodiesterase (PDE) compartmentalize cAMP signaling pathways in mesangial cells (mc).
  Chini CSC, Grande JP, Chini EN, Dousa TP, J Am Soc Nephrol, 1/1/1996
• Synthesis and localization of adrenomedullin (ADM) in rat mesangial cells (mc).
  Chini EN, Grande JP, Jougasaki M, Burnett JC, Dousa TP, J Am Soc Nephrol, 1/1/1996
• Relationship between proteinuria and histopathologic changes in glomeruli in mesangioproliferative glomerulonephritis (MSGN) elicited by anti-thy-1.1-Monoclonal antibo...
  Grande JP, Shankland SJ, Walker HJ, Chini EN, Tsuboi Y, Johnson RJ, Dousa TP, J Am Soc Nephrol, 1/1/1996
• Localization of the calcium-sensing receptor along the rat nephron.
  Caride AJ, Chini EN, Homma S, Dousa TP, Penniston JT, J Am Soc Nephrol, 1/1/1995
• Suppression of rat mesangial cell (mc) proliferation by thyrphostins, the inhibitors of tyrosine protein kinase (PTK)
  Thompson MA, Chini EN, Grande JP, Dousa TP, J Am Soc Nephrol, 1/1/1995
• All trans-retinoic acid stimulates NA+-dependent phosphate (P) uptake and other NA+-dependent cotransporters in opossum kidney (OK) cells. (Abstract 1506)
  Beers KW, Toledo FGS, Chini EN, Dousa TP, FASEB J, 1/1/1995
• Nicotinic acid adenine dinucleotide phosphate: a novel calcium release messenger in sea urchin eggs. (Abstract TU-POS525)
  Chini E, Perez C, Beers K, Clapham DE, Dousa TP, Biophys J, 1/1/1995
• Inhibitors of cAMP phosphodiesterase (PDE) isoenzymes block mesangial cell production of monocyte chemo-attractant protein-1 (MCP-1).
  Grande JP, Chini CS, Chini EN, Melder DC, Radford MG, Dousa TP, Journal of Investigative Medicine, 1/1/1995
• Specific modulation of cyclic ADP-ribose induced Ca2+ release by polyamines. (Abstract no. 730)
  Chini EN, Beers KW, Chini CS, Dousa TP, FASEB J, 1/1/1995
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Lectures

• Cellular Metabolism in the Treatment of Pancreatic Cancer 
  1/1/2014
• Central Anesthesia M&M 
  Mayo Clinic, Rochester, MN - 1/1/2013
• Regulating the Regulator: Role of DBC1 in Epigenetics and Energy Metabolism 
  Yale University School of Medicine, New Haven, CT - 1/1/2013
• NAD Signaling Pathways: Key Roles in Metabolic Regulation in Health and Disease. 
  Rochester, MN - 1/1/2013
• Targeting NAD Metabolism in Pancreatic Cancer Cells: Role of SIRT1, Nampt, and CD38 in Therapy of Pancreatic Cancer 
  Rochester, MN - 1/1/2013
• Targeting NAD Metabolism in Pancreatic Cancer Cells: Role of SIRTUINS, CD38, and Nampt in Therapy of Pancreatic Cancer 
  Rochester, MN - 1/1/2013
• Physiology of Metabolic Syndrome 
  Rio de Janeiro, Brazil - 1/1/2013
• Current and Future Perspectives in Metabolic Syndrome Therapy 
  Rio de Janeiro, Brazil - 1/1/2013
• New Experimental Concepts in Obesity and Related Metabolic Dysfunction 
  Mayo Clinic, Rochester, MN - 1/1/2013
• New Experimental Concepts in Obesity and Age Related Metabolic 
  Mayo Clinic, Rochester, MN - 1/1/2013
• Anesthesia for Liver Transplant 
  Salvador, Brazil - 1/1/2012
• Is There a Role for Caloric Restriction (CR) and CR Mimetics for the Prevention and Treatment of Polycystic Kidney Disease? 
  Mayo Clinic, Rochester, MN - 1/1/2012
• Targeting NAD Metabolism in Cancer Cells 
  Rochester, MN - 1/1/2012
• Manipulating NAD Metabolism in Cancer 
  Rochester, MN - 1/1/2012
• Transfusion Medicine 
  Salvador, Brazil - 1/1/2012
• NAD(P) in Cell Signaling: from Calcium to Epigenetics. A Tale of Life, Death, and Everything In Between 
  Federal University of Minas Gerais, Belo Horizonte, Brazil - 1/1/2012
• Role of CD38 and DBC1 in the Regulation of SIRT1 
  University of South Florida, Tampa, FL - 1/1/2012
• Role of CD38 and DBC1 in the Regulation of SIRT 1 
  Ventura, CA - 1/1/2012
• Research in Anesthesiology; Transfusion Medicine for the Anesthesiologist 
  Wayne State University, Detroit, MI - 1/1/2012
• Can We Stop Aging with NAD? 
  University of Rio de Janeiro, Rio de Janeiro, Brazil - 1/1/2011
• NAD Metabolism for Everyone 
  Mayo Clinic, Rochester, MN - 1/1/2011
• Molecular Biology of Aging for the Anesthesiologist 
  Walter Reed Medical Center, Washington, DC - 1/1/2011
• Role of NAD Metabolism in Regulation of Cell Function 
  Los Angeles, CA - 1/1/2011
• Role of the NAMPT-CD38-SIRT1-NAD Axis in Pancreatic Cancer 
  Rochester, MN - 1/1/2011
• CD38 and DBC1 as Regulator of SIRT1: Regulating the Regulator 
  Northwestern University, Chicago, IL - 1/1/2010
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