DushyantPurushottamPurohitMD

PubMed

• 20 citations
  Genome-wide association study and functional validation implicates JADE1 in tauopathy.
  Kurt Farrell, SoongHo Kim, Natalia Han, Megan A. Iida, Elias M. Gonzalez
  Acta Neuropathologica. 2021-11-01
• 39 citations
  Predictors of cognitive impairment in primary age-related tauopathy: an autopsy study
  Megan A. Iida, Kurt Farrell, Jamie M. Walker, Timothy E. Richardson, Gabriel A. Marx
  Acta Neuropathologica Communications. 2021-08-05
• 73 citations
  Single-nucleus transcriptome analysis of human brain immune response in patients with severe COVID-19.
  John F. Fullard, Hao-Chih Lee, Georgios Voloudakis, Shengbao Suo, Behnam Javidfar
  Genome Medicine. 2021-07-19

Journal Articles

• Cell cycle checkpoint abnormalities during dementia: A plausible association with the loss of protection against oxidative stress in Alzheimer's disease [corrected]  
  Katsel P, Tan W, Fam P, Purohit DP, Haroutunian V, PLoS One, 1/1/2013
• Characterizing Cognitive Deficits and Dementia in an Aging Urban Population in India  
  Nair G, Van Dyk, U. Shah, D. P. Purohit, C. Pinto, A. B. Shah, H. Grossman, D. Perl, V. Ganwir, S. Shanker, and M. Sano, Int J Alzheimer's Dis, 1/1/2012
• Serum lipids are related to Alzheimer’s pathology in nursing home patients  
  Lesser GT, Haroutunian V, Purohit DP, Schnaider Beeri M, Schmeidler J, Honkanen L, Neufeld R, Libow LS, Dement Geriatr Cogn Disord, 1/1/2009
• Parkinson’s disease dementia: a diminished role for the Lewy body  
  Libow LS, Frisina PG, Haroutunian V, Perl DP, Purohit DP, Parkinsonism Relat Disord, 1/1/2009
• Less Alzheimer’s disease neuropathology in medicated hypertensive than normotensive persons  
  Hoffman LB, Schmeidler J, Lesser GT, Beeri MS, Purohit DP, Grossman HT, Haroutunian V, Neurology, 1/1/2009
• Clinical dementia rating performed several years prior to death predicts regional Allzheimer's neuropathology  
  Schnaider Beeri M, Silverman JM, Schmeidler J, Wysocki M, Grossman HZ, Purohit DP, Perl DP, Haroutunian V, Dement Geriatr Cogn Disord, 1/1/2008
• Role of neuropathology of Alzheimer’s disease in dementia in the oldest old  
  Haroutunian V, Schnaider-Beeri M, Schmeidler J, Wysocki M, Purohit DP, Perl DP, Libow LS, Lesser GT, Maroukian M, Grossman HT, Arch Neurol, 1/1/2008
• Pituicytoma presenting with spontaneous hemorrhage: Case report  
  Benveniste RJ, Purohit D, Byun H, Pituitary, 1/1/2006
• Coronary artery disease is associated with Alzheimer’s disease neuropathology in APOE 4 carriers  
  Beeri MS, Rap M, Silvrman J, Schmeidler J, Grossman HT, Fallon JT, Purohit DP, Perl, DP. Siddiqui A, Lesser G, Rssendorff, C, Haroutunian, V, Neurology, 1/1/2006
• Microglia activation in the brain as inflammatory biomarker of Alzheimer's disease neuropathology and clinical dementia  
  Xiang Z, Haroutunian V, Ho L, Purohit D, Pasinetti GM, Dis Markers, 1/1/2006
• Type 2 diabetes is negatively associated with Alzheimer's disease neuropathology  
  Beeri MS, Silverman JM, Davis KL, Marin D, Grossman HZ, Schmeidler J, Purohit DP, Perl DP, Davidson M, Mohs RC, Haroutunian V, J Gerontol A Biol Sci Med Sci, 1/1/2005
• Isolated autonomic failure as an initial presentation of Parkinson’s disease and dementia with Lewy bodies  
  Kaufmann H, Nahm K, Purohit D and Wolfe D, Neurology, 1/1/2004
• Depression in AutopsyConfirmed Dementia with Lewy Bodies and Alzheimer's Disease  
  Samuels SC, Brickman AM, Burd JA, Purohit DP, Qureshi PQ, Serby M, Mt Sinai J Medicine, 1/1/2004
• Co-occurrence of essential tremor and Parkinson’s disease: Clinical study of a large kindred with autopsy findings  
  Yahr MD, Orosz D, Purohit DP, Parkinsonism and Related Disorders, 1/1/2003
• Cognitive burden and excess Lewy body formation in the Lewy body variant of Alzheimer Disease  
  Serby M, Brickman AM, Haroutunian V, Purohit DP, Marin, D, Lantz M, Mohs RC, Davis, KL, Am J Geriatric Psychiatry, 1/1/2003
• Severe generalized dystonia due to primary putaminal degeneration: Case report and review of the literature  
  Walker RH, Purohit DP, Good P, Perl DP, Brin, MF, Movement Disorders, 1/1/2002
• Altered synapsin a-type but not b-type isoform in brain of patients at high risk for Alzheimer's disease assessed by DNA-microarray technique  
  Ho, L, Guo, Y, Spielman, L, Haroutunian, V, Purohit DP, Czernik, A, Yemul, S, Aisen, PS, Mohs, R, Pasinetti, GM, Neurosci Lett, 1/1/2001
• Intramedullary spinal enterogenous cysts: Case report and review of the literature  
  Lippman CR, Argineteau M, Purohit DP, Naidich TP, Camins MB, J Neurosurgery, 1/1/2001
• Plaques and Cognitive Decline  
  S Parvathy, Davies P, Haroutunian V, Purohit DP, Davis KL, Mohs RC, Park H, Moran TM, Chan JY, Buxbaum JD, Arch Neurol, 1/1/2001
• Neuronal cyclooxygenase-2 in the hippocampal formation as a function of the clinical progression of Alzheimer's disease  
  Ho L, Purohit DP, Haroutunian V, Luterman JD, Willis, F, Naslund J, Buxbaum, JD, Mohs RC, Aisen PS, Pasinetti, GM, Arch Neurol, 1/1/2001
• Cytokine gene expression as a function of the clinical progression of Alzheimer's disease dementia  
  Luterman JD, Haroutunian V,Yemul S, Ho L, Purohit DP, Aisen PS, Mohs R, Pasinetti GM, Arch Neurol, 1/1/2000
• Contribution of Lewy body inclusions to dementia in patents with and without Alzheimer’s disease  
  Haroutunian V, Serby M, Purohit DP, Perl DP, Marin D,, Lantz, M, Mohs RC, Davis KL, Arch Neurol, 1/1/2000
• Cholinergic markers are not decreased in early Alzheimer’s disease  
  Davis KL. Mohs RC, Marin DB, Purohit DP, Perl DP, Lantz M, Austin G, Haroutunian V, JAMA, 1/1/1999
• Regional distribution of neurofibrillary tangles in non-demented elderly and cases od very mild Alzheimer’s disease  
  Haroutunian V, Purohit DP, Perl DP, Marin D, Khan K, Lantz, M, Davis KL, Mohs RC, Arch Neurol, 1/1/1999
• Neuropeptide abnormalities in the patients with early Alzheimer Disease  
  Davis KL, Mohs RC, Marin DB, Purohit DP, Perl DP, Lantz, M, Austin G, Haroutunian V, Arch Gen Psychiatry, 1/1/1999
• Join now to see all

Books/Book Chapters

• Neuroimaging:The Essential 
  Chapter: Normal Anatomy of the Brain: What You Need to Know. 
  Page 16 - 39De Leary R, Fowkes ME, Yourtry TA, Habil M, Purohit D, Carpenter DM and Naidich TPEditors: Pina C. Sanelli, Pamela W. Schaefer and Laurie A. Loevner.Wolters Kluwer2015
• Cingulate Neurobiology and Disease 
  Chapter: Cingulate Subregional Neuropathology in Dementia with Lewy Bodies and Parkinson’s disease with Dementia. 
  Page 708 - 728Brent A. Vogt, Leslie Vogt, Purohit Dushyant P and Patrick R. HofEditors: Brent A Vogt.Oxford U. Press2009
• New Advances in Toxicology and Epidemiology. 
  Chapter: Amyotrophic lateral sclerosis in Caucasian Mainland U.S. born long-term resident on Guam - A case report including neuropathological examination in ALS. 
  Page 99 - 102Perl DP, Steele JC, Purohit DPEditors: F. Clifford Rose and Forbes H. Norris.Smith-Gordon, London1990

Abstracts/Posters

• Age-Related Cognitive Loss in Mumbai, India, A Research Partnership 2004-2012.
  Purohit DP, Sano M, Batheja P, Pinto, Deshpande J, Shah AB and Jashnani J, 10th Anniversary Brain Disorders in Developing Countries Symposium, NIH Campus, Bethesda, MD, 1/11/2014
• A Clinicopathological Correlation Study of Cognitive Status and Senile Plaques and Neurofibrillary Tangles in Clinically Well- Characterized Individuals of Extreme old...
  Purohit DP, FASEB Journal; Eighty-Fourth Annual Meeting of American Association of Neuropathologists, San Diego, CA, 1/1/2008
• Clinical and neuropathologic studies of age-related cognitive loss in Mumbai, India.
  Purohit DP, Alzheimer’s and Dementia; 10th International Conference on Alzheimer's Disease and related Disorders, Madrid, Spain, 1/15/2006

Lectures

• Type-2 Diabetes, Cognitive Impairment and Dementia 
  Sir HN Reliance Foundation Hospital and Research Center, Mumbai, India - 1/13/2015
• Single Episode of Severe Axonal Injury in Humans Can Lead to Tau Pathology Resembling Chronic Traumatic Encephalopathy. 
  Portland, OR - 1/12/2014
• Direct and Indirect Impacts of Research Collaborations in Developing Countries 
  NIH Campus, Bethesda, MD - 1/11/2014
• Review and Diagnostic Application of the NIA-AA Guidelines for Neuropathological Assessment of Alzheimer’s disease 
  Chicago, IL - 1/22/2012
• Advancement of Clinical Services and Research on Dementia in an Urban Setting in India through International Collaboration 
  Nairobi, Kenya - 1/4/2012
• Progress in Research Development on Dementia in NIH funded Project in Mumbai, India. 
  Nairobi, Kenya - 1/28/2007
• Neuropathology of Dementia in India. 
  Nairobi, Kenya - 1/22/2001
• Pathobiologic correlates of dementia. 
  Jewish Home & Hospital, Bronx, NY - 1/20/1999
• Alzheimer’s disease and allied dementing disorders. 
  Jewish Home and Hospital, New York, NY - 1/16/1999
• Diffuse plaque formation in the cerebral cortex of non-demented elderly and individuals with mild to moderate dementia. 
  Amsterdam, Netherlands - 1/1/1998
• Neuropathologic evidence for the existence of Alzheimer’s disease in an urban population of Bombay, India. 
  Vancouver, British Columbia, Canada - 1/1/1996
• Alzheimer’s disease and allied neurodegenerative Diseases: Neuropathological diagnosis. 
  New Delhi, India - 1/1/1995
• Pathology of Alzheimer’s disease: The significance of neuropathologic study of non-demented elderly. 
  Grant Medical College, Bombay, India - 1/1/1995
• Alzheimer's disease and related neurodegenerative diseases in elderly schizophrenic patients. 
  San Antonio, TX - 1/1/1995
•  
  Toronto, Ontario, Canada - 1/1/1994
• ALS/Parkinsonism complex of Guam among Filipino migrants to Guam. 
  St. Louis, MO - 1/1/1992
• Dementia in elderly schizophrenics: is it related to the superimposed Alzheimer's disease? 
  Baltimore, MD - 1/1/1991
• Primary cerebellar degeneration presenting as progressive familial dementia. 
  Toronto, Canada - 1/1/1990
• Alzheimer-type Pathology in Dentate Gyrus of the Hippocampus. 
  Dallas, TX - 1/1/1989
• Identification of an Atypical Senile Dementia Syndrome. 
  Newcastle upon Tyne, England - 1/5/1988
• Intracranial Hemorrhage in a Case of Neuro-syphilis. 
  London, England - 1/1/1986
• Neuropathology of Alzheimer’s disease. 
  Newcastle upon Tyne, England - 1/5/1985
• Pathological significance of neurofibrillary tangle formation in mid brain and brain stem nuclei in Alzheimer's disease. 
  Bristol, England - 1/1/1985
• Join now to see all