DukheeBettyLewMD

PubMed

• 28 citations
  Inherited GATA2 Deficiency Is Dominant by Haploinsufficiency and Displays Incomplete Clinical Penetrance
  Carmen Oleaga-Quintas, Edgar Borges de Oliveira-Júnior, Jérémie Rosain, Franck Rapaport, Caroline Deswarte
  Journal of Clinical Immunology. 2021-01-08
• 7 citations
  Questioning Cause and Effect: Children with Severe Asthma Exhibit High Levels of Inflammatory Biomarkers Including Beta-Hexosaminidase, but Low Levels of Vitamin A and...
  Amali E. Samarasinghe, Rhiannon R. Penkert, Julia L. Hurwitz, Robert E. Sealy, Kim S. LeMessurier
  Biomedicines. 2020-10-06
• Improving allergy skin testing proficiency.
  Rachna R. Dave, Catherine Hammond, Charles W. Stewart, D. Betty Lew
  Annals of Allergy, Asthma & Immunology. 2019-04-05

Journal Articles

• Complementary use of topical bitter melon for atopic dermatitis: A case report  
  D Park, NP Tran, JM Duncan and DB Lew, Alternative Medicine Studies, 1/1/2012
• Interaction between innate and adaptive immunity in asthma pathogenesis: new perspectives from studies on acute exacerbations  
  Pattanaik D, Katcher JS, Nozad CH, Robinson WS Jr, Tran NP, Michael CF, and Lew DB, J Allergy Clin Immunol, 1/1/2010
• Recurrent stridor in a 9-year-old child after a choking and aspiration [Vocal Cord Dysfunction]  
  Sternberg TG, Thompson JW, Schoumacher RA, Lew DB, Allergy Asthma Proc, 1/18/2009
• CME Examination, Management of Chronic Obstructive Pulmonary Disease: Moving Beyond the Asthma Algorithm  
  Michael CF, Katcher JS, Nozad CH, Tran NP, Robinson WS and Lew DB, J Allergy Clin Immunol, 1/1/2009
• Innate Microbial Sensors and their Relevance to Allergy  
  Michael CF, Nozad CH, Rohman E, Katcher JS and Lew DB, J Allergy Clin Immunol, 1/1/2008
• Lung remodeling in asthma  
  Lew DB and Lieberman PL, Allerg Clinical Immunol International, 1/1/2003
• Enzymatic methylation of arginyl residues in -Gly-Arg-Gly- peptides  
  Hyun Y-L, Lew DB, Park SH , Kim C-W, Paik WK, and Kim S, Biochem J, 1/1/2000
• Effect of dexamethasone on bovine airway smooth muscle cell proliferation  
  Dixon ER, Weinberg JA, and Lew DB, J Asthma, 1/1/1999
• Adverse reaction to prednisone in a patient with systemic lupus erythematosus  
  Lew DB, Higgins GC, Skinner RB, Snider MD, and Myers LK, Pediatr Dermatol, 1/1/1999
• Beta-Hexosaminidases: Potent mitogens of airway smooth muscle  
  Lew DB, Allergy Asthma Proc, 1/1/1998
• Anaphylaxis due to parenteral nutrition in a 4 yr old child  
  Market AD, Lew DB, Schropp KP, and Hak EB, J Pediatr Gastroent Nutrit, 1/1/1998
• Contribution of PKC to beta-hexosaminidase-induced airway smooth muscle proliferation  
  Lew DB, Brown ER, Dempsey BK, Wright HM, and Malik KU, Am J Physiol (Lung Cell Mol Physiol), 1/1/1997
• Ulcerative contact gingivitis due to the nickel component of stainless steel crowns  
  Barcroft B, Shen TJ, and Lew DB, Pediatr Asthma, Allergy & Immunol, 1/1/1997
• A mannose receptor mediates mannosyl-rich glycoprotein-induced mitogenesis in bovine airway smooth muscle cells  
  Lew DB, Songu-Mize E, Pontow SE, Stahl PD and Rattazzi MC, J Clin Invest, 1/1/1994
• Inflammatory mediators in airway muscle proliferation  
  Lew DB, Tran N and Weil ML, Pediatr Asthma, Allergy & Immunol, 1/1/1992
• Prostaglandin E2 synthesis elicited by adrenergic stimuli in guinea pig trachea is mediated primarily via activation of beta2 adrenergic receptors  
  Lew DB, Nadel GL and Malik KU, Prostaglandins, 1/1/1992
• Mitogenic effects of lysosomal hydrolases on bovine tracheal myocytes in culture  
  Lew DB, and Rattazzi MC, J Clin Invest, 1/1/1991
• The role of endogenously-derived leukotrienes in the regulation of lysosomal enzyme expression in macrophages exposed to beta 13-glucan  
  Lew DB, Leslie CC, Henson PM, and Riches DWH, J Leuk Biol, 1/1/1991
• The effect of adding atropine sulfate to a maximal dose of isoetharine inhalation in pediatric acute asthma  
  Lew DB, Herrod HG, and Crawford LV, Ann Allergy, 1/1/1990
• Induction of macrophage lysosomal hydrolase synthesis and secretion by beta 13-glucan  
  Lew DB, Leslie CC, Riches DWH, and Henson PM, Cell Immunol, 1/1/1986
• Effect of developmental stages on arginase and urea production in the liver of rat  
  Paik WK, Lew B, Farooqui J, and Kim S, Biochem Med, 1/1/1984
• Enzymatic methyl esterification of E coli ribosomal proteins  
  Kim S, Lew B and Chang FN, J Bacteriol, 1/1/1977
• Studies on the natural substrate for protein methylase II in mammalian brain and blood  
  Kim S, Wasserman L, Lew B, and Paik WK, J Neurochem, 1/1/1975
• Studies on the effect of hypophysectomy on protein methylase II of rat  
  Kim S, Wasserman L, Lew B, and Paik WK, FEBS Lett, 1/1/1975
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Books/Book Chapters

• Conn's Current Therapy 
  Chapter: Anaphylaxis and serum sickness. Section 12 
  Page 811 - 813Belleau J and Lew DBEditors: R.E. Rakel.W.B. Saunders Co., Orlando, FLEdition 55th,2003
• Atlas of Allergic Diseases 
  Chapter: Immunology Laboratory Techniques. Chapter 8 
  Page 63 - 69Lew DBEditors: Lieberman PL and Blaiss MS.Current Medicine Inc., Current Science Group, Philadelphia, PAEdition 1st,2001
• Comprehensive Pediatrics 
  Chapter: Allergic diseases. Chapter 27 
  Page 783 - 814Crawford LV and Lew DBEditors: J.G. Hughes and R.L. Summitt.C.V. Mosby Co., St. Louis, MOEdition 7th,1990
• Conn's Current Therapy 
  Chapter: Anaphylaxis and serum sickness. Section II 
  Page 661 - 663Lew DB and Herrod HGEditors: R.E. Rakel.W.B. Saunders Co.Edition 40th,1988
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Abstracts/Posters

• Skin Puncture Test Response Is Not Altered by Season of Testing.
  S. S. Warford, D. B. Lew, C. F. Michael, J. A. Lieberman, AAAAI Annual Meeting, Los Angeles, CA, 1/1/2016
• Induction of Krüppel-Like Transcription Factor (KLF4&5) by Baker’s Yeast Mannan in Human Bronchial Epithelial and smooth Muscle Cells.
  K. S. LeMessurier, Jeoung-Eun Park, Ae-Kyung Yi, C. Y. Song, K. U. Malik and D. B. Lew, 24th World Allergy Congress, Seoul, Korea, 1/1/2014
• Mucin Inhibition by Mannan from Saccharomyces (S.) cerevisiae in Allergic Mice.
  J. K. Patel, J. H. Chang, A. Samarasinghe, and D.B. Lew, Pediatric Research Day, Children’s Foundation Research Center, Le Bonheur Children’s Medical Center, 1/1/2013
• Chronic inflammatory demyelinating polyneuropathy in a patient with ADA deficient SCID: A case report.
  DA Petty, ME Conley, N Shah, DB Lew and CF Michael, Annals of Allergy, Asthma & Immunol; ACAAI Annual Meeting, Baltimore, MD, 1/1/2013
• Complement C8 deficiency presenting as urticaria and polyarthralgias: Case report.
  D. Park, LK Myers, ML Brown, DB Lew, Annals of Allergy, Asthma & Immunol; Annual ACAAI meeting, Boston, MA, 1/1/2011
• A Young Child with Hyper IgE syndrome (HIES)with a Novel Variant in Signal Transduction and Activator of Transcription (STAT3) and Disseminated Histoplasmosis.
  W Robinson, J Vickery, C Michael, S Arnold, R Schoumacher, R Chesney, K Lakin, J Ward, E Pivnick, D Lew, J Allergy Clin Immunol; the annual AAAAI meeting; Le Bonheur Children’s Hospital Research Day, Memphis, TN, 2010; San Francisco, CA, 2011, 1/1/2011
• Complementary use of topical bitter melon for atopic dermatitis: A case report.
  D Park, NP Tran, JM Duncan and DB Lew, Annals of Allergy, Asthma & Immunology; annual ACAAI meeting, Phoenix, AZ, 1/1/2010
• Ophthalmic Wegener’s granulomatosis (WG) with underlying allergic conjunctivitis.
  N Daher, DB Lew, CF Michael, JS Fahhoum, Eastern Allergy Conference, Palm Beach, FL, 1/1/2009
• Vancomycin Hypersensitivity Diagnosed by Lymphocyte Blast Transformation.
  Nguyen P. Tran, Jeremy Katcher, Erin Rohman, Mary Francis Hall, Christie F. Michael, and D. Betty Lew, Annals of Allergy, Asthma & Immunol; American College of Allergy, Asthma & Immunology Annual Meeting, Miami Beach, FL, 1/1/2009
• Vocal Cord Dysfunction
  precipitated by choking and aspiration event in a 9 yr male., Annal Alergy, Asthma, Immunol; ACAAI meeting, Seattle, WA, 1/1/2008
• Inhibition of airway Smooth Muscle (ASM) Remodeling by Mannan from Saccharomyces cerevisiae.
  A. Roberson, E. Rohman, C. Michael, T. Overbeck and D. Lew, J Allergy Clin Immunol; annual meeting of AAAAI, Philadelphia, PA, 1/1/2008
• Pivnick Family’s Fatal Mystery Disease Discovered to be IPEX Syndrome.
  A. Redding, M. Roberts, D. Lew, C. Michael, M. Conley, S. Dowell, J. Ward and E, Annals of Allergy; ACAAI annual meeting, Dallas, TX, 1/1/2008
• Saccharomyces (S.) cerevisiae Mannan Facilitates Airway Epithelial Repair
  C Michael, K Chapman, B Lew, C Waters, J Allergy Clin Immunol; annual meeting of AAAAI, San Diego, CA, 1/1/2007
• Omalizumab Downregulates the Expression of CD23 (FceRII) on Human Bronchial Smooth Muscle Cells (HBSMC) in Vitro
  M. R. Streck, J. Tole, R. K. Gandhi, T. M. Loun, C. W. Stewart, D.B. Lew, J Allergy Clin Immunol; annual meeting of AAAAI, Miami, FL, 1/1/2006
• Immunoregulatory Effects of Saccharomyces (S.) cerevisiae Mannan via Th2/Th3 Polarization in Mice.
  J Lehman, M Streck, A Tyagi, DB Lew, J Allergy Clin Immunol; annual meeting of AAAAI, Miami, FL, 1/1/2006
• Mannan from the Saccharomyces cerevisiae inhibits ovalbumin-induced allergic asthma in mice.
  T Overbeck, C Michael, WS Robinson, R Gandhi, L Waikart, J Lehman, J Smith and DB Lew, Allergy Clin Immunol Int: J World Allergy Org; XIXth World Allergy Organization Congress, Munich, Germany, 1/1/2005
• Susceptibility to asthma phenotype in human airway smooth muscle mannose receptor (huASM-MR) transgenic mice
  W Robinson, C Michael, T Overbeck, F Kirkland, E Bonten, A d’Azzo and B Lew, J Allergy Clin Immunol; annual meeting of AAAAI, San Francisco, CA, 1/1/2004
• Maintenance Asthma Treatment with Fluticasone/Salmeterol combination via Diskus: Effect on outcomes in inner city children enrolled in TennCare.
  C Stewart, W Nguyen, Fisher K, DB Lew, E Tolley, and T Self, J Allergy Clin Immunol; annual meeting of AAAAI, San Francisco, CA, 1/1/2004
• Beneficial effect of a elemental formula in eosinophilic pustuloderma associated with hyper IgE syndrome and cow’s milk allergy.
  V. Hernandez-Trujillo, J. T. Belleau, M. Jeng, M. E. Conley, and D. B. Lew, J Allergy Clin Immunol; annual meeting of AAAAI, Denver, CO, 2003; San Francisco, CA, 2004, 1/1/2003
• Mannose receptor mediated sustained activation of extracellular regulated kinase 1 & 2 (ERK1/2) is dependent on fibronectin synthesis in human airway smooth muscle cells.
  L. Young and D. B. Lew, J Allergy Clin Immunol; annual meeting of AAAAI, Denver, CO, 1/1/2003
• Regulation of CD23 expression in Human Airway smooth Muscle Cells.
  J. T. Belleau, N. Morelli, R. Gandhi, and D. B. Lew, J Allergy Clin Immunol; annual meeting of AAAAI, Denver, CO, 1/1/2003
• Effect of RBL-1 cell mediators on human airway smooth muscle (asm) cell proliferation
  Morelli N, Belleau JT, Lew DB, Ann Allergy; ACAAI meeting, San Antonio, TX, 1/1/2003
• Isolation and Expression of Full Length cDNA Clone of Human Airway Smooth Muscle Mannose Receptor (ASM-MR).
  Zhao Y, Bonten E, d'Azzo A, Lew DB, J Allergy Clin Immunol; AAAAI annual meeting, New York, NY, 1/1/2002
• Selective Mitogenic Effect of IL-13 on Bovine Airway Smooth Muscle Cells (ASMC) is due to the Lack of IL-2R gamma chain Expression.
  McPherson HM, Lyles DL, Zhao Y, Dempsey BK, Lew DB, J Allergy Clin Immunol; AAAAI annual meeting, New Orleans, LA, 1/1/2001
• Mitogenic effect of IL-13 in airway smooth muscle cells
  Lew DB, Lyles DL, Dempsey BK, Zhao Y, J Invest Med; AAAAI annual meeting; SSPR Annual Meeting, New Orleans, LA, 2000; San Diego, CA, 2000, 1/1/2000
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Lectures

• Xolair Therapy 
  University of Tennessee Health Science Center, Memphis, TN - 1/1/2014
• Mannan derived from Saccharomyces cerevisiae: A Potential Therapeutic for Asthma. 
  University of Tennessee Health Science Center, Memphis, TN - 1/1/2008
• Mannose Binding Protein 
  Philadelphia, PA - 1/1/2008
• Milk Protein Allergy and Eosinophilic Enterocolitis 
  Michigan State University, East Lansing, MI - 1/1/2006
• Evaluation and Management of Drug AllergyAnaphylaxis 
  Michigan State University, East Lansing, MI - 1/1/2006
• Smooth Muscle Remodeling in Asthma and Treatment Strategies 
  Michigan State University, East Lansing, MI - 1/1/2006
• The Great Asthma Raft Debate – Smooth Muscle 
  Boston, MA - 1/1/2004
• Yeast Mannan – Preclinical Trials 
  Memphis, TN - 1/1/2004
• The new asthma guidelines - will they improve care? 
  Memphis, TN - 1/1/2003
• Outpatient management and prevention of asthma 
  East Tennessee State Medical Center - 1/1/2003
• Systemic Anaphylaxis 
  East Tennessee State Medical Center - 1/1/2003
• Lung Remodeling – therapeutic Implications 
  East Tennessee State Medical Center - 1/1/2003
• Mechanisms of beta-Hexosaminidase-induced lung remodeling in asthma. 
  UTHSC - 1/1/2002
• Pediatric Asthma: Bench to Bedside. 
  Nassau University Medical Center, East Meadow, Long Island, NY - 1/1/2001
• Beta-Hexosaminidases: Potent mitogens of airway smooth muscle. 
  Palm Beach, FL - 1/1/1998
• Airway smooth muscle proliferation induced by mannosyl-rich glycoproteins. 
  Korea University, Seoul, Korea - 1/1/1997
• Chronic asthma care. 
  Le Bonheur Children's Medical Center - 1/1/1997
• Signal transduction mechanism of airway smooth muscle proliferation induced by mannosyl-rich glycoproteins. 
  UTHSC - 1/1/1995
• Mediators of asthma. 
  Nashville, TN - 1/1/1993
• Future therapeutic targets in asthma. 
  Memphis, TN - 1/1/1993
• Second messenger systems involved in beta-hexosaminidase-induced mitogenesis in bovine tracheal myocytes. 
  Cape Cod, MA - 1/1/1992
• Pathogenesis of Asthma 
  Ewha Woman's University, Seoul, Korea - 1/1/1991
• Outpatient Management of Asthma 
  Bisson Clinic, Memphis, TN - 1/1/1991
• Mitogenic effect of lysosomal hydrolases 
  Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA - 1/1/1990
• Mitogenic effect of lysosomal hydrolases. 
  Fairfield Glade, TN - 1/1/1990
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