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Office
800 Spruce St
Philadelphia, PA 19107Phone+1 215-829-3000Fax+1 215-829-7564
Education & Training
- University of Pennsylvania Health SystemFellowship, Blood Banking/Transfusion Medicine, 1990 - 1991
- University of Pennsylvania Health SystemResidency, Pathology-Anatomic and Clinical, 1987 - 1991
- Perelman School of Medicine at the University of PennsylvaniaClass of 1987
- Harvard UniversityPhD, Biophysics, 1977 - 1983
- Brown UniversityB.Sc., Biophysics, with Honors, 1973 - 1977
Certifications & Licensure
- PA State Medical License 1989 - 2024
- American Board of Pathology Clinical Pathology
Awards, Honors, & Recognition
- Elected to The Academy of Master Clinicians Penn Medicine, 2013
- Elected Fellow College of American Pathologists, 2013
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012
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Publications & Presentations
PubMed
- 50 citationsIntrathecal bivalent CAR T cells targeting EGFR and IL13Rα2 in recurrent glioblastoma: phase 1 trial interim results.Stephen J Bagley, Meghan Logun, Joseph A Fraietta, Xin Wang, Arati S Desai
Nature Medicine. 2024-05-01 - 836 citationsCRISPR-engineered T cells in patients with refractory cancerEdward A. Stadtmauer, Joseph A. Fraietta, Megan M. Davis, Adam D. Cohen, Kristy L. Weber
Science. 2020-02-28 - 1064 citationsDeterminants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemiaJoseph A. Fraietta, Simon F. Lacey, Elena Orlando, Iulian Pruteanu-Malinici, Mercy Gohil
Nature Medicine. 2018-04-30
Journal Articles
- Persistence of anti-desmoglein 3 IgG+ B-cell clones in pemphigus patients over yearsHammers, C., Chen, J., Lin, C., Kacir, S., Siegel, D.L., Payne, A.S., Stanley, J.R., J Invest Dermatol, 1/1/2014
- Carbohydrate sequence of the prostate cancer-associated antigen F77 assigned by a mucin O-glycome designer arrayGao, C., Liu, Y., Zhang, H., Zhang, Y., Fukuda, M.N., Palma, A.S., Kozak, R.P., Childs, R.A., Nonaka, M., Li, Z., Siegel, D.L., Hanfland, P., Peehl, D.M., Chai, W., Gr..., J Biol Chem, 1/1/2014
- The receptor for advanced glycation end products mediates lung endothelial activation by RBCsMangalmurti N.S., Friedman J.L., Wang L.C., Stolz D.B., Muthukumaran G., Siegel D.L., Schmidt A.M., Lee J.S., Albelda S.M., Am J Physiol - Lung Cell Mol Physiol, 1/1/2013
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Books/Book Chapters
Abstracts/Posters
- Successful red blood cell gemotyping from leukoreduced packed red blood cell segments.Azzato E., Gentile C., Carpenter H., Siegel D., Watt C., Annual Meeting of the Association for Molecular Pathology, National Harbor, MD, 1/1/2014
- Stem cell mobilization with Plerixafor + G-CSF in comparison to cyclophosphamide + G-CSF and time-to-progression after autologous stem cell transplantation for multipl...Garfall A.L., Dougherty A.L., Vogl D.T., Weiss B.W., Cohen A.D., Mangan P.A., O’Doherty U., Siegel D.L., Porter D.L., Stadtmauer E.A., Blood, 1/1/2013
- Deuterium-hydrogen exchange coupled with mass spectrometry revealed a novel autoantibody binding epitope and substrate recognition site in ADAMTS13 protease.Casina V., Wenbing H., Hanby H., Siegel D.L., Mayne L., Englander S.W., Zheng X.L., Blood, 1/1/2013
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Lectures
- High-Performance Hematology: Elite Athletes and Weekend Warriors60th American Society of Hematology Annual Meeting - 12/3/2018
- High-Performance Hematology: Elite Athletes and Weekend Warriors60th American Society of Hematology Annual Meeting - 12/1/2018
- Update on Hematopoietic Stem Cell TransplantationSan Diego, CA - 1/1/2014
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Other
- Methods for Isolation of Antibody Binding to Cells.Siegel D.L., United States Patent Office, #8,623,594 B2
1/7/2014 - Drug Delivery to Human Tissues by Single Chain Variable Region Antibody Fragments Cloned by Phage Display.Stanley J.R., Amagai M., Siegel D.L., United States Patent Office, #8,470,323 B2
1/25/2013 - Compositions, Methods, and Kits for Detection of an Antigen on a Cell and in a Biological Mixture.Siegel D.L., United States Patent Office, #8,586,293 B2
1/19/2013 - Join now to see all
Press Mentions
- Glioblastoma Multiforme Translational Center of ExcellenceMarch 1st, 2019
Grant Support
- Transfusion Medicine Research Training ProgramNational Heart, Lung, And Blood Institute2001–2011
- Phage Display Tools For Automated Blood TypingNational Heart, Lung, And Blood Institute2006–2007
- Phage Display Tools For Automated Blood TypingNational Heart, Lung, And Blood Institute2003–2004
- Monoclonal ITP Autoantibodies--Paradigm For AutoimmunityNational Heart, Lung, And Blood Institute1998–2002
- Cellular And Humoral Aspects Of ImmunomodulationNational Heart, Lung, And Blood Institute2000
- Characterization Of The Anti-Rh Alloimmune ResponseNational Heart, Lung, And Blood Institute1996–2000
- Biology Of Human Warm Autoimmune Hemolytic AnemiaNational Heart, Lung, And Blood Institute1991–1993
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