DennisMFrismanMDFCAP, FASCP

Anatomic Pathology, Clinical Pathology, Surgical Pathology

Senior Pathologist, Eisenhower Medical Center Medical Director, Qualtek Molecular Laboratories Consultant and Inventor of ImmunoQuery, Elsevier

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Office
39000 Bob Hope Dr
Rancho Mirage, CA 92270
Phone+1 760-340-3911

Fax+1 760-773-1587

Education & Training

University of CaliforniaB.S, 1976
Armed Forces Institute of PathologyResidency, Immunohistochemistry Director; Interim Head of Cytopathology, 1989 - 1990
Massachusetts General HospitalFellowship, Allergy and Immunology, 1987 - 1989
University of California (San Diego) Medical CenterResidency, Pathology-Anatomic and Clinical, 1984 - 1987
University of California (San Diego) Medical CenterResidency, Pathology-Anatomic and Clinical, 1983 - 1987
University of California (San Francisco)Internship, Pathology-Anatomic and Clinical, 1983 - 1984
University of California San Diego School of MedicineClass of 1983
N.I.H. Medical Scientist Trainee, University of CaliforniaPathology Research, 1977 - 1982

Certifications & Licensure

CA State Medical License 1985 - 2026
American Board of Pathology Anatomic Pathology & Clinical Pathology

Awards, Honors, & Recognition

Lectureship Award Loma Linda Pathology Group Swatek, 2004
College of American Pathologists President’s Award 2003
Defense Meritorious Medal 1992
Summa Cum Laude University of California, Los Angeles, 1976
Highest Honors in Biochemistry University of California, Los Angeles, 1976
Merck Award for Research in Biochemistry University of California, Los Angeles, 1976
Phi Beta Kappa University of California, Los Angeles, 1975
President's Fellowship University of California, Los Angeles, 1975
National Science Foundation Grant University of California, Los Angeles, 1975
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Publications & Presentations

PubMed

32 citations
Expression of the HER-2/neu proto-oncogene in serous ovarian neoplasms.
Jeffrey D. Seidman, Dennis M. Frisman, Henry J. Norris
Cancer. 1992-12-15
64 citations
Fetal rhabdomyoma of the head and neck: A clinicopathologic and immunophenotypic study of 24 cases
Silloo B. Kapadia, Jeanne M. Meis, Dennis M. Frisman, Gary L. Ellis, Dennis K. Heffner
Human Pathology. 1993-07-01
17 citations
Melanocytic activation in HIV-1 disease: HMB-45 staining in common acquired nevi
Kathleen J. Smith, Henry G. Skelton, William L. Heimer, Donald Baxter, Peter Angritt
Journal of the American Academy of Dermatology. 1993-10-01

Journal Articles

Cytotoxic activity of graft-infiltrating lymphocytes correlates with cellular rejection in cardiac transplant patients.
Frisman, D.M., Fallon, J.T., Hurwitz, A.A., Dec, W.G., Kurnick, J.T, Human Immunology 32:241-245
Ehrlichiosis mimicking thrombotic thrombocytopenic purpura: case report and pathological correlation.
Marty, A.M., Dumler, J.S., Imes, G., Brusman, H.P., Smrkovski, L.L., Frisman, D.M, Hum Pathol 26: 920-925
Immunohistochemical features in inflammatory linear verrucous epidermal nevi suggest a distinctive pattern of clonal dysregulation of growth.
Welch, M.L., Smith, K.J., Skelton, H.G., Frisman, D.M., Yeager, J., Angritt, P., Wagner, K.F, J Amer Acad Dermatol. 29: 242-248
Melanocytic activation in HIV-1 disease: HMB-45 staining in common acquired nevi.
Smith, K.J., Skelton, H.G., Heimer, W., Baxter, D., Angritt, P., Frisman, D., Wagner, K.F, J. Amer. Acad. Dermatol. 29:539-544
Clear cell sarcoma of tendons and aponeuroses: a clinicopathologic study of 58 cases with analysis of prognostic factors.
Montgomery, E.A., Meis, J.M., Ramos, A.G., Frisman, D.M., Martz, K.L, Int J Surg Pathol 1:89-100
Melanotic neuroectodermal tumor of infancy. Immunohistochemical and DNA Flow Cytometric study.
Kapadia, S.B., Frisman, D., Ellis, G., Hitchcock, C., Popek, E, Am J. Surg. Pathol. 17:566-573
Fetal rhabdomyomas of the head and neck. Clinicopathologic and immunophenotypic study.
Kapadia, S.B., Meis, J.M., Frisman, D.M., Ellis, G.L., Heffner, D, Human Pathology 24:754-765
Adult rhabdomyoma of the head and neck. Clinicopathologic and immunophenotypic study.
Kapadia, S.B., Meis, J.M., Frisman, D.M., Ellis, G.L., Hyams, V.J., Heffner, D.K, Human Pathology
Immunocytochemistry in the differential diagnosis of effusions: use of logistic regression analysis to select a panel of antibodies to distinguish adenocarcinomas fro...
Frisman, D.M., McCarthy, W., Schleiff, P., Buckner, S-B, Nocito, J.D., O'Leary, T., Modern Pathology 6:179-184
Histopathology and immunohistologic findings associated with inflammatory dermatoses in human immunodeficiency virus type I disease and their correlation with Walter R...
Smith K.J., Skelton, H.G., Yeager, J., Angritt, P., Frisman, D., Wagner, K.F., Baxter, D., James, W.D., Oster, C.N, J Amer Acad Dermatol 28: 174-184
Expression of the HER-2/neu proto-oncogene in serous ovarian neoplasms.
Seidman, J.D., Frisman, D.M., Norris, H.J, Cancer 70: 2857-2860
Verrucous lesions secondary to DNA viruses in patients infected with the human immunodeficiency virus in association with increased factor XIIIa-positive dermal dendri...
Smith, K.J., Skelton, H.G., Frisman, D.M., Angritt, P, J Am Acad Dermatol 27:943-950
Papular eruption of HIV disease: A review of the clinical, histologic, and immunohistochemical findings in forty-eight cases.
Smith, K.J., Skelton III, H.G., James, W.D., Frisman, D.M., Barrett, T.L., Angritt, P., Lupton, G.P, Am J of Dermatopathol 13:445-451
Affinity labeling of the subunits of the membrane-associated cholinergic receptor.
Weiland G., Frisman D., Taylor P, Molec Pharm 15:213-226
Clonal analysis of graft-infiltrating lymphocytes from renal and cardiac biopsies. Dominant rearrangements of TcR beta genes and persistence of dominant rearrangement...
Frisman, D.M., Hurwitz, A.A., Bennett W.T., Boyle L.A., Kurnick J.T, Human Immunology 28:208-215
AIDS-related Kaposi's Sarcoma displays differential expression of endothelial surface antigens.
Scully, P.A., Steinman H.K., Kennedy C., Trueblood K., Frisman D.M., Voland J.R, Am J Path 130:244-251
Expression of an endothelial surface antigen on activated human lymphocytes: Lymphocyte subset distribution and kinetics of antigen activation.
Voland J.R., Frisman D.M., Fan Q., Dutton R.W, Cell Immunol 110:197-208
Presence of an endothelial antigen on the syncytiotrophoblast of human chorionic villi. Detection by a monoclonal antibody.
Voland J., Frisman D.M., Baird S, Am J. Reprod Immunol 11:24-30
The use of monoclonal antibodies and flow cytometry to detect peripheral blood and bone marrow involvement of a diffuse poorly differentiated lymphoma.
Shawler D.L., Wormsley S.B., Dillman R.O., Frisman D.M., Baird S.M., Glassy M.C., Royston I, Int J Immunopharmacol 7:423-432
Characterization of a monoclonal antibody that reacts with activated/proliferating cells and subsets of leukemia cells.
Dillman R.O., Shawler D.L., Frisman, D.M., Fox, R.L., Royston, I, J Biol Response Mod 3:26-38
Altered cell surface antigen expression in bladder carcinoma detected by a new hemagglutinating monoclonal antibody.
Rearden A., Nachtsheim D.A., Frisman D.M., Chiu P., Elmajian D.A., Baird S.M, J Immunol 131:3073-3077
Immunohistologic analysis of lymphoid infiltrates in primary Sjogren's syndrome using monoclonal antibodies.
Adamson T.C. III, Fox R.I., Frisman D.M., Howell F.V, J Immunol 130:203-208
Analysis of B-cell antigens in normal reactive lymphoid tissue using four B-cell monoclonal antibodies.
Hofman F.M., Yanagihara E., Byrne B., Billing A., Baird S., Frisman D., Taylor C.R, Blood 62:775-783
Characterization of a monoclonal antibody that reacts with an activation antigen on human B cells: reactions on mitogen-stimulated blood lymphocytes and cells of norm...
Frisman D., Slovin S, Royston I., Baird S., Blood 62:1224-1229
Membrane antigen on Epstein-Barr virus-infected human B cells recognized by a monoclonal antibody.
Slovin S.F., Frisman D.M., Tsoukas C.D., Royston I., Baird S.M., Wormsley S.B., Carson D.A., Vaughan J. H, Proc Natl Acad Sci USA 79:2649-2653
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Books/Book Chapters

Immunomicroscopy: A Diagnostic Tool for the Surgical Pathologists.
Chapter: Immunohistology of the skin: melanoma, intermediate filaments
Frisman, D.M. and Taylor, C.REditors: C.R. Taylor.W.B. Saunders Company, Philadelphia, PAEdition 1,
Immunomicroscopy: A Diagnostic Tool for the Surgical Pathologists.
Chapter: Immunohistology of the skin: melanoma, intermediate filaments
Frisman, D.M. and Taylor, C.REditors: C.R. Taylor.Philadelphia, PAEdition 2,
Methods in Molecular Biology, Vol. 34: Immunocytochemical Methods and Protocols.,
Chapter: Overview of immunocytochemical approaches to the differential diagnosis of tumors. Diagnostic applications in the clinical laboratory
Frisman, D.MEditors: L.C. Javois.Humana Press, Inc, Totowa, NJ
Advanced Diagnostic Methods in Pathology: Principles, Practice, and Protocols.
Chapter: Antigens
Frisman, D.M. and O'Leary, T.JEditors: T.J. O'Leary.Saunders Company, Philadelphia, PA
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Abstracts/Posters

Characterization of lymphocyte populations in myocardial biopsies of human allografts.
Frisman, D.M, International Symposium on Inflammatory Heart Disease, Snowmass, CO
Sinonasal Hemangiopericytoma (SNHPC).
Kapadia, S.B., Meis, J.M., Frisman, D., Wenig, B.M., Heffner, D.K, Modern Pathology 6:81A
Adult rhabdomyoma (RM) of head and neck. A clinicopathologic and immunophenotypic study.
Kapadia, S., Meis, J.M., Frisman, D., Zimmer, G., Ellis, G., Hyams, V., Heffner, D, Modern Pathology 5:72A
Fetal rhabdomyoma (FRM) of the head and neck: A clinicopathologic and immunophenotypic study.
Kapadia, S., Meis, J.M., Frisman, D., Ellis, G., Hyams, V., Heffner, D, Modern Pathology 5:72A
Melanotic neuroectodermal tumor of infancy (MNTI). Immunohistochemical and flow cytometric study.
Kapadia, S., Frisman, D., Hitchcock, C., Ellis, G., Popek, E, Modern Pathology 5:71A
Malignant melanoma of soft parts (MMSP): A clinicopathologic study of 58 cases.
Montgomery, E.A., Meis, J.M., Ramos, A.G., Frisman, D., Martz, K.L, Modern Pathology 5:10A
Use of monoclonal antibody BER-EP4 in the diagnosis of effusions.
Frisman D.M., Buckner S.H., Nocito J.D., Marsella R., O'Leary T.J., Lab Invest 64:25a
Interactions among lymphocytes propagated from sequential human cardiac allograft biopsies,
Frisman, D.M., Fallon, J.T., Boyle, L.A., Kurnick, J.T, Poster, International Symposium on Inflammatory Heart Disease, Snowmass, CO
Evidence for Clonal Dominance among lymphocytes propagated from endomyocardial biopsies of human allografts.
Bennett, W.P., Frisman, D.M., Boyle, L.A., Leary, C.P., Fallon, J.T., Kurnick, J.T, Poster, International Symposium on Inflammatory Heart Disease, Snowmass, CO
Monoclonal antibody identification of an antigen on follicular center cells of normal and malignant lymph nodes.
Frisman D., Slovin S., Royston I., Baird S, Blood 58:158a
Endothelial surface markers on Kaposi's Sarcoma support a vascular origin for the tumor.
Scully P.A., Frisman D., Voland J, Lab Invest 58:82a
Characterization of a lymphocyte activation antigen present on syncytiotrophoblast and endothelium.
Voland J., Frisman D., Schmunk G., Baird S, Poster, Third International Congress of Reproductive Immunology, Toronto, Canada
Trophoblast-endothelial cross-reactive antigen detected by a monoclonal antibody.
Voland J., Frisman D., Baird S, Am J Reprod Immunol and MIcrobiol 131
Immunohistologic analysis of lymphoid infiltrates in Sjogren's Syndrome using monoclonal antibodies.
Adamson T.C. III, Howell F.V., Frisman D.M., Robinson C.A., Vaughan J.H., Fox R.I, American Rheumatism Association Western Regional Meeting
Identification of lymphocytes infiltrating synovial membrane in rheumatoid arthritis.
Fox R.I., Adamson T.C. III, Frisman D., Royston I., Vaughan J.H, Pan American Congress of Rheumatology
Specific red cell adherence test using a new hemagglutinating monoclonal antibody.
Rearden A., Nachtsheim D.A., Frisman D., Elmajian D., Chiu R., Baird S.M, Am Urol Assoc Annual Meeting, Las Vegas
Monoclonal antibody which recognizes an early B lymphocyte activation antigen on B lymphocytes.
Frisman D.M., Baird S.M, Proc 1st Internat Workshop on Human Leukocyte Differentiation Antigens, Paris, France
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